Strong Positive Correlation Research Articles

The more self-control, the more anxious?- A network analysis study of the relationship between self-control and psychological anxiety among Chinese university students.

With the growing prevalence of anxiety symptoms among university students, self-control is an important potential influence. This study aims to understand the network structure of self-control and anxiety, and to identify the core symptoms within this network. It will provide a theoretical basis for the prevention and intervention of anxiety symptoms in university students. We used network analysis to study anxiety and self-control in 3,792 university students from six schools in Heilongjiang Province, China. We checked for linear connections in the networks using a restricted cubic spline. We conducted the analyses and made graphs using R software. (i) The total sample network showed that higher levels of self-control in university students were associated with lower anxiety levels and were validated by the restrictive cubic spline. (ii) There was the strongest negative correlation (edge weight = -0.42) between Without thinking (SC7) and Panic (A5), and the edge weight coefficients of this self-control component and anxiety symptoms were greater than those of other self-control components. (iii) Physical exertion (A6) and Scared (A7) were identified as the core symptoms of the overall network, with expected influence of 1.08 and 1.08 (Z-score). (iv) A significant difference was observed between the anxiety positive network structure and the total sample network structure, with the strongest positive correlation between Iron self-control (SC3) and Breathing difficulty (A2) (edge weight = 0.22), with the strongest negative correlation between Certain things (SC2) and Situations (A4) (edge weight = -0.35). (v) The self-control component Iron self-control (SC3) had only one positive edge in the rural network, and only two positive edges in not one child network. The present study offered a new perspective on the relationship between self-control and anxiety using network analysis for the first time. The control component Without thinking (SC7) was an important concept influencing the negative correlation of anxiety, and Physical exertion (A6) and Scared (A7) were core symptoms in the total network. Heterogeneity analyses showed a tendency for the more self-controlled to be more anxious in the anxiety positive sample. These results may be a potential target for preventing and intervening anxiety in university students.

Standardization of color measurement in the medical photography in clinical practice

BACKGROUND: For many medical specialties, photography is a routine element of work. Environmental factors equally and significantly influence the interpretation of colour light perception and the quality of photographic recording. Standardization of conditions in medical photography is necessary for subsequent quantitative assessment of the postoperative skin scar by analysing colour coordinates in the RGB system. AIM: To determine the impact of illumination and shooting distance at colour coordinates when studying unaltered skin. METHODS: Five volunteers without any skin diseases and no make-up on their facial skin were taken in the study. Skin type by the Fitzpatrick scale was II–III. Digital photography was made with a mobile device camera at distance 30 cm from the subject. For each participant, a series of digital photographs was taken at a distance of 20, 30, 40, 50, 60, 70 cm from the light source. Colour coordinates in the RGB system were measured in the digital graphics editor Adobe Photoshop CS6. Statistical analysis of the obtained data was carried out using Microsoft Office Excel 2019, Phyton 3.11. RESULTS: The analysis of variance by the ANOVA method was used as a statistical analysis. In order to determine a statistically significant difference between the sets, Tukey HSD test was performed. A total of 1764 coordinates of three colours were subjected to statistical analysis (R=588, G=588, B=588). When constructing a heat map of the cross-correlation of the absolute values of each colour at each distance, taking into account the type of light source among themselves, the data had a strong direct correlation, regardless of the study area. When constructing a linear graph, coordinates of any of the zones were located on the same straight line. CONCLUSION: Photography conditions were experimentally determined under which the color interpretation of light is constant. Results of the study should be taken into account during medical photography and subsequent color assessment of postoperative skin scars.

A Stepwise‐Clustered Precipitation Downscaling Method for Ensemble Climatic Projections in the Mediterranean Region

ABSTRACTPrecipitation changes dynamically in the Mediterranean region. Therefore, the projection of future precipitation and its historical distribution mechanism is essential for climate mitigation and adaptation. In this study, a stepwise clustered precipitation downscaling method (SCPD) was developed and adopted in the Mediterranean region to reveal the inherent variation rules and trends over the future 100 years under two SSP scenarios. A cutting and merging multivariate process is introduced to build a cluster tree for supporting further downscaling and projecting steps. The ensemble average from the global climate model (GCM) dataset is used for precipitation projections. The precipitation performance of SCPD, evaluated by R2, is fairly decent. The precipitation projections vary with the original rainfall patterns over the gauge stations. Dry places tend to become comparably drier in the future. Precipitation in the northern Mediterranean region shows a drier winter–spring and wetter summer–autumn. Opposite trends emerged in the southern part, with increasing winter precipitation and decreasing summer rainfall. The rising carbon dioxide concentration will further intensify the decrease in rainfall. However, the centres of these two EOFs are not identical. The contributions of NAO (positive) and Niño 3.4 (negative) to PC1 are relatively high. Accordingly, the strongest positive correlation with PC2 is SCAND, as well as negative correlations with AO, NAO and EAWR. Positive anomaly precipitation is attributed to PC1, whereas PC2 is responsible for most of the negative variance precipitation.

The Influence of Emotional Instability on Weight Fluctuations

This study examines the relationships between psychological factors, specifically mood fluctuations, short temper, and feelings of negativity, and their impact on weight gain or loss among individuals. The objective is to determine how these emotional states individually and collectively influence weight changes, focusing on understanding their predictive power. A quantitative, cross-sectional design was employed. The analysis involved correlation and multiple regression techniques to explore the relationships between the variables. Results revealed that moodiness has the strongest positive correlation with weight changes and is the most significant predictor, explaining a substantial portion of the variance. Short temper and feelings of negativity also contributed to body weight variations, though to a lesser extent. The model explained the variance in weight outcomes, highlighting the meaningful role of psychological factors in weight management. This study contributes to the growing body of research emphasizing the need to integrate mental health support in weight management programs and policy interventions, recognizing the critical role of mental well-being in influencing physical outcomes such as weight fluctuations. The findings have important implications for healthcare providers, policymakers, and wellness programs aiming to address health's psychological and physical aspects.

Laparoscopic surgery and mortality in perforated peptic ulcer (correlation and regression

Aim of the study is to evaluate the relationship between the number of laparoscopic operations and mortality in patients with perforated peptic ulcer. Materials and methods: The functional relationships between the number of performed laparoscopic operations and the levels of hospital and postoperative mortality were studied based on the analysis of the results of surgical treatment of patients with a perforated ulcer in 2018. Results: An analysis of the functional relationships between the number of laparoscopic operations performed and mortality was carried out based on the results of primary statistical information (2 189 patients with a perforated ulcer). Strong direct correlations have been established, which can be most reliably described within the framework of polynomial regression models (r2 = 0.917 and r2 = 0.889). Conclusion: An assessment of trends in the reduction in hospital and postoperative mortality with an increase in number of laparoscopic operations will be determined only with standardized approaches to the usage of minimally invasive technologies in all areas of the Russian Federation.

Interferon as an immunoadjuvant to enhance antibodies following influenza B infection and vaccination in ferrets

Despite annual vaccination, influenza B viruses (IBV) continue to cause significant morbidity and mortality in humans. We have found that IBV infection resulted in a weaker innate and adaptive immune response than influenza A viruses (IAV) in ferrets. To understand and overcome the weak immune responses to IBV in ferrets, we administered type-I or type-III interferon (IFN) to ferrets following infection or vaccination and evaluated their effects on the immune response. IFN signaling following viral infection plays an important role in the initial innate immune response and affects subsequent adaptive immune responses. In the respiratory tract, IFN lambda (IFNL) has regulatory effects on adaptive immunity indirectly through thymic stromal lymphopoietin (TSLP), which then acts on immune cells to stimulate the adaptive response. Following IBV infection or vaccination, IFN treatment (IFN-Tx) upregulated gene expression of early inflammatory responses in the upper respiratory tract and robust IFN, TSLP, and inflammatory responses in peripheral blood cells. These responses were sustained following challenge or vaccination in IFN-Tx animals. Serum IFNL and TSLP levels were enhanced in IFN-Tx animals following challenge/rechallenge over mock-Tx; however, this difference was not observed following vaccination. Antibody responses in serum of IFN-Tx animals following IBV infection or vaccination increased more quickly and to higher titers and were sustained longer than mock-Tx animals over 3 months. Following rechallenge of infected animals 3 months post treatment, antibody levels remained higher than mock-Tx. However, IFN-Tx did not have an effect on antibody responses following challenge of vaccinated animals. A strong direct correlation was found between TSLP levels and antibody responses following challenge-rechallenge and vaccination-challenge indicating it as a useful tool for predicting adaptive immune responses following IBV infection or vaccination. The effects of IFN on strengthening both innate and adaptive responses to IBV may aid in development of more effective treatments following infection and improved influenza vaccines.

The impact of weather patterns on inter-annual crop yield variability

Inter-annual variations in crop production have significant implications for global food security, economic stability, and environmental sustainability. Existing crop yield prediction models primarily using meteorological variables may not adequately encapsulate the full breadth of weather influences on crop development processes, such as compound or extreme events. Incorporating weather patterns into crop models could provide a more comprehensive understanding of the environmental conditions affecting growth, enabling more accurate and earlier yield predictions.Our study examines 30 distinct UK Met Office weather patterns (MO30) based on mean sea level pressure. We investigate their association with weather conditions that limit winter wheat yield in the UK (1990–2020). Blocked, negative North Atlantic Oscillation (NAO) patterns create the highest risk of temperatures that are below optimal for crop yield. However, the connection between weather patterns and yield is complex, with differing effects at a regional scale and even at which point in the growth cycle they appear. It was found that anticyclonic weather patterns during sowing, emergence, vernalisation, anthesis, and grain filling exhibit a relationship with good crop yields with a Spearman correlation coefficient of up to 0.55 for a single weather pattern (WP3 during vernalisation in South East England), whilst cyclonic patterns can help during the terminal spikelet phenological phase. The strongest positive correlations were during sowing, emergence, and vernalisation, whilst the largest negatives were observed in anthesis and grain filling.The potential of combining weather patterns with existing crop simulation models to produce earlier and more accurate yield predictions is shown. This would enable effective crop management and climate mitigation strategies, critical to strengthening food security. Projected changes in weather pattern occurrences in the late 21st century will likely reduce crop yields. This is due to increased cyclonic weather patterns, which bring warmer, wetter conditions during the wheat's vernalisation stage, followed by warmer, drier conditions during the anthesis and grain-filling phases.

Bioelectrical Impedance Analysis Demonstrates Reliable Agreement with Dual-Energy X-ray Absorptiometry in Identifying Reduced Skeletal Muscle Mass in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Hypertension.

Background/Objectives: Body composition (BC) affects the risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD) and hypertension (HTN). Currently, dual-energy X-ray absorptiometry (DEXA) is considered the gold standard for assessing BC, even though it has some limitations, including immobility, ionizing radiation, and patient weight restrictions. The aim of the study was to evaluate the correlations of BC parameters measured by bioelectrical impedance analysis (BIA) with those measured by DEXA in patients with MASLD and HTN. Methods: Overall, 78 patients with MASLD and HTN underwent the following study procedures: compilation of an anamnesis, physical examination of a patient, laboratory tests, abdominal ultrasound, BIA, DEXA, and anthropometric measurements. Results: The agreement between BIA and DEXA in diagnosing reduced skeletal muscle mass (SMM) in patients with MASLD and HTN was moderate (kappa values were 0.440 and 0.404 in males and females, respectively). Significant strong direct correlations were found between fat mass (FM) and body fat percentage measured by BIA with corresponding measurements by DEXA (p < 0.001 for both). The area under the receiver operating characteristic curves (AUC) of SMM to body weight ratios calculated using BIA data were 0.834 and 0.929 for reduced appendicular SMM determined by DEXA in males and females with MASLD and HTN, respectively. Conclusions: In conclusion, BIA is an easy-to-use and widely available tool for assessing SMM and FM in patients with MASLD and HTN, demonstrating reliable agreement with DEXA measurement results and completely free of its limitations.

EARLY MANIFESTATIONS OF HEART FAILURE AND ACTIVITY OF SYSTEMIC INFLAMMATION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION DEPENDING ON RISK FACTORS

Acute myocardial infarction and heart failure (HF) resulting from this condition remain complex and not fully understood problems in cardiology. It is important to detect early manifestations of HF and optimize treatment to prevent pathological myocardial remodeling and the occurrence of adverse events. The increase in systemic inflammation activity (SIA) and the presence of comorbidities in patients contribute to the development of HF. The aim of the study- to investigate the impact of risk factors (RF) such as arterial hypertension (AH), diabetes mellitus (DM), history of COVID-19, and obesity on the occurrence of HF and SIA in patients with ST-elevation myocardial infarction (STEMI) who underwent percutaneous coronary intervention. Materials and Methods. The study involved 50 patients from the cardiology and reperfusion therapy department of St. Panteleimon Hospital in Lviv (66,00 (52,43-78,35) % men and 34,00 (21,65-47,57) % women), with an average age of 62,01±10,30 years. Blood levels of NT-proBNP (a biomarker of HF) and C-reactive protein (CRP) (a biomarker of SIA) were analyzed on the day of hospitalization for STEMI (the first day from the onset of clinical symptoms, stenting of the infarct-related coronary artery). Results were evaluated using descriptive statistical analysis methods (mean and standard deviation; median and percentile, fractions and their 95 % confidence intervals, calculated by the Wald and Fisher methods), unpaired Student's t-test, and Pearson correlation analysis. Results. The average NT-proBNP levels in the studied patients were 0,50 (0,30; 2,60) ng/ml, and CRP levels were 10,50 (6,00; 20,80) IU/ml (p&lt;0,05, compared to normal parameters). NT-proBNP levels significantly (p&lt;0,05) exceeded the upper reference limit in the presence of AH (0,50 (0,30; 3,30) ng/ml); DM (0,61 (0,30; 4,37) ng/ml); history of COVID-19 (0,61 (0,32; 3,36) ng/ml) (as well as without this RF – 0,49 (0,15; 1,37) ng/ml); obesity (0,31 (0,19; 380) ng/ml). The average NT-proBNP levels in patients with a history of COVID-19 were significantly (p&lt;0,05) higher compared to those in patients without it. CRP levels in blood were significantly (p&lt;0,05) higher than normal values in patients with AH (11,05 (5,60; 25,90) IU/ml); DM (15,20 (7,06; 25,20) IU/ml) (as well as without this RF – 9,50 (5,54; 18,20) IU/ml); history of COVID-19 (12,52 (8,20; 19,65) IU/ml) (as well as without it in history – 9,99 (5,60; 20,06) IU/ml); obesity (9,63 (6,52; 35,00) IU/ml) (as well as without this RF – 10,50 (5,81; 18,40) IU/ml). Average CRP levels in patients with DM and a history of COVID-19 were significantly (p&lt;0,05) higher compared to those without these RFs. The correlation between NT-proBNP and CRP levels was direct – strong in the presence of DM (r=0,78; p=0,012) and history of COVID-19 (r=0,70; p=0,001), medium strength in patients with AH (r=0,55; p=0,0004). Conclusions. In patients with STEMI who underwent myocardial revascularization, early manifestations of HF and a significant increase in SIA occur within the first day of the disease, promoted by such risk factors as AH, DM, history of COVID-19, and obesity. In the presence of DM and history of COVID-19, CRP should be considered an early marker of HF occurrence alongside NT-proBNP, as indicated by a strong direct correlation between these indicators in this category of individuals.

Profiling mRNA and miRNA expression variations associated with cyclin-dependent kinase pathway in the low-grade luminal early breast cancer.

Luminal A and B subtypes of breast tumors have fluctuated in proliferation rates, which arise from cell cycle dysregulation in cancer. Besides, microRNAs can regulate various cell processes through integration with mRNA. miRNAs that target the cell cycle are significant because of their prediction capability of prognosis. The objective of this study is to discover the integration between miRNA-mRNA and miRNA-miRNA related to cyclin-dependent kinase. Thirty-four pairs of human primary breast cancer and tumor margin samples from luminal breast cancer patients were investigated to assess the expression levels of CCND1, E2F1, miR-124, miR-503, miR-449a, and miR-449b. Afterward, the expression levels of mRNAs and miRNAs were investigated by real-time PCR. Statistical analysis was conducted to compare the expression levels between breast cancer and corresponding normal tissues. The protein expressions of E2F1 and CCND1 were verified by western blotting. Further, the correlation between mRNAs and miRNAs was calculated. E2F1 was significantly increased in both luminal A and B patients, while CCND1 was upregulated only in luminal B. Significant differences in all miRNAs were detected in both luminal A and B biopsy specimens (p < 0.0001). The correlation analysis revealed a positive strong correlation between miR-124 and E2F1 in luminal A patient. Moreover, the correlation test confirmed the ability of miR-449a to increase the CCND1 gene in luminal B subtypes. Also, miRNA correlation exhibited the miRNA-miRNA interaction in luminal breast cancer. This study demonstrated the novel miRNA-mRNA and miRNA-miRNA interactions, providing new insights into the molecular integration in luminal A and B patients. The authors propose that this research could contribute to introducing valuable biomarkers for luminal cancerous cells.

Regulation of root-associated microbiomes and root exudates by different tobacco species

BackgroundThe root-associated microbiomes are crucial in promoting plant growth and development through symbiotic interactions with their hosts. Plants may shape their microbiomes by secreting specific root exudates. However, the potential mechanisms how plant species determine root exudates and drive microbiome assembly have been little studied. In this study, three wild tobaccos and one cultivated tobacco were used to investigate the commonalities and differences of both root-associated microbiomes and root exudates.ResultsAmplicon sequencing results suggested that tobacco species significantly affected microbial communities in both the rhizosphere and root endosphere, with the strongest impact on the fungal community in the root endosphere. The microbial networks of wild tobacco species were more stable than that of the cultivated tobacco, and fungal members played a more important role in the networks of wild tobacco species, while bacterial members did so in the cultivated tobacco. The rhizosphere bacteria of wild tobacco species showed a higher functional diversity than that of the cultivated tobacco, while the bacteria in the root endosphere presented a contrary pattern. Metabolomics analysis showed significant differences in the composition and abundance of root exudates among the four tobacco species, and the greatest difference was found between the three wild species and the cultivated one. Correlation analysis showed the strongest correlation between metabolites and rhizosphere bacteria, in which O-benzoic acid (2-methoxybenzoic acid) had the most positive correlations with rhizosphere bacteria, while β-ureidoisobutenoic acid had the most negative correlations with rhizosphere bacteria. The rhizosphere bacteria Streptomyces, Hydrophilus and Roseobacter had the strongest positive correlations with metabolites, and the rhizosphere bacterium Nitrobacter had the most negative correlations with metabolites.ConclusionThis study revealed the differences of microbial communities and root exudates in the rhizosphere and root endosphere of four tobacco species, which can further improve our understanding of plant–microbiome interactions during crop domestication.Graphical

Fecal zonulin as a prognostic marker of atopic march in children with food allergy

Introduction. The onset of allergic diseases most often occurs in early childhood with the onset of food allergies, which can subsequently lead to the implementation of the atopic march. Increased intestinal permeability with high production of zonulin, the main moderator of intestinal tight junctions, can be an important link in the development of comorbid allergic diseases.Material and methods. In order to study the significance of fecal zonulin as a marker for predicting the atopic march in children with food allergy, a cross-sectional retrospective study was conducted on 73 children aged 5 years who were diagnosed with food allergy (FA) to cow’s milk proteins in the first year of life. In all children, when the diagnosis was made in the first year of life, the content of zonulin in feces was determined using the ELISA method.Results. As a result of dynamic observation, all children with food allergy were divided into 2 groups: the first group consisted of children with food allergy who developed allergic rhinitis and/or bronchial asthma within 5 years (group I, n = 39), group 2 consisted of 34 children with food allergy who did not implement the atopic march within 5 years of observation (group II, n = 34). Our study showed statistically significant differences in the fecal zonulin level in the first year of life: group I Me = 2.39 ng/ml (Q1-Q3: 1.78–2.65 ng/ml), group II Me = 1.85 ng/ml (Q1-Q3: 0.49–0.91 ng/ml), p = 0.034. Strong direct correlations were found (Spearman correlation coefficient S = 0.681 (p &lt; 0.05)) between the zonulin level in feces at the onset of the disease and the development of allergic rhinitis and/or bronchial asthma up to 5 years of age, the data were confirmed by comparing the areas under the curves during ROC analysis, AUC in the study of fecal zonulin as a prognostic marker of the risk of atopic march in children is 0.887, the optimal threshold (cutoff point) is 1.94 ng/ml.Conclusions. Fecal zonulin level in children with food allergy can be an effective prognostic marker of atopic march development, its values in feces above 1.94 ng/ml allow us to predict with a high degree of probability the risk of atopic march development in children with food allergy to cow’s milk proteins within 5 years

Модуляція цілісності кишкового бар’єру курчат-бройлерів, асоційована зі змінами мікробіому

Cell adhesion proteins play a crucial role in ensuring the barrier function of the intestinal epithelium by forming intercellular tight junctions that prevent the invasion of harmful substances, microorganisms, and toxins into the organism’s internal environment. However, the comprehensive impact of SCFA-M on the modulation of these proteins and their connection with the microbiome of the duodenal intestine of broiler chickens has been overlooked by researchers, thus emphasizing the significance of these studies. The research was carried out on Cobb 500 broiler chickens in conditions of industrial poultry farming. The experimental group chickens were administered with SCFA-M in drinking water (1% solution of C-3 C-10). The results of the experiment revealed that the administration of SCFA-M to chickens was characterized by increased expression of E-cadherin, fibronectin, IFN-α, and decreased expression of IFN-γ in the duodenum of broiler. Specifically, SCFA-M administration to chickens was associated with an increase in the expression level of E-cadherin in the duodenal intestine by 25.8–30.4% (P≤0.001), fibronectin by 17.8–37.0% (P≤0.001), IFN-α by 21.0–71.6% (P≤0.001), and a decrease in the expression of IFN-γ by 13.5%–49.9% (P≤0.01–0.001) compared to the control group chickens. The correlations of molecular marker expression (E-cadherin, fibronectin, IFN-α, and IIFN-γ) in the duodenum of broiler chickens significantly varied throughout the technological cycle not only in magnitude but also in its trend. Obtained results demonstrated that the marker content was positively correlated with Escherichia coli content (r = 0.79–0.87) in 22-day-old broiler chickens. Contrary, marker content was negatively correlated with E. coli content (r = –0.84…–0.68), Staphylococcus spp. and Enterococcus spp. (r = 0.23–0.91) in 29-day-old chickens. Furthermore, this index was negatively correlated with Staphylococcus spp. content (r = –0.83…–0.51) in 45-day-old chickens. The exposure to SCFA-M induced the changes which associated with strong direct correlations of E-cadherin, fibronectin, IFN-α, and IFN-γ with Staphylococcus spp. content in the duodenum of 22-day-old broiler chickens (r = 0.81–0.91). Molecular markers content exhibited strong inverse correlation links with E. coli content in 36-day-old broiler chickens (r = –0.92…–0.80). Thus, the application of SCFA-M induced the beneficial effect on the modulation of molecular marker expression (E- cadherin, fibronectin, IFN-α, and IFN-γ) in the duodenum. The further research required to construct the optimized protocols for SCFA-M applying in poultry farming, which would replace or minimize the use of antibacterial drugs.

Effect of Mindfulness on Treatment Motivation in Patients with Substance Use Disorder

Objective: This research aimed to assess the mindfulness levels among individuals with substance use disorder (SUD) and investigate its influence on treatment motivation.&#x0D; Method: A descriptive and cross-sectional study was carried out involving 184 SUD patients. Data collection utilized a Personal Information Form, The Mindful Attention Awareness Scale (MAAS), and the Treatment Motivation Questionnaire (TMQ).&#x0D; Results: A strong positive correlation was identified between MAAS and TMQ levels (r: 0.796, p

The role of wise leadership in enhancing the dimensions of the smart organization: An analytical study of the opinions of a sample of employees at Tikrit University

The study aimed to clarify the concepts of the dimensions of the smart organization and the degree of their availability, study the role of this leadership at the University of Tikrit, and determine the impact of wise leadership in achieving the dimensions of the smart organization. A questionnaire was designed and distributed to A sample consisting of (280) administrators at the University of Tikrit. The descriptive analytical method was also adopted in Study, based on analysis. The study reached the following results: There is a type of strong, positive correlation and direct impact of wise leadership in enhancing the dimensions of the smart organization at the University of Tikrit. There is a strong correlation and positive impact of digital management in enhancing the performance of the smart organization Yes, there is a kind of strong correlation and significant positive effect of leadership skills on the dimensions of the organization. There is a strong direct correlation and a direct impact of wisdom in dealing with enhancing the dimensions of the smart organization. There is a kind of strong correlation and a direct impact of the ability to influence the dimensions of the smart organization. There is a strong correlation and impact of the strategic vision In the dimensions of the smart organization.

The Influence of Organisational Justice on Employee Performance in the Organised Private Sector of the Nigeria Economy

This study examined the Influence of Organisational Justice on Employee Performance in the Organised Private Sector of the Nigeria Economy. This study employs a quantitative research design, using a survey approach to collect data from 107 Respondents from the Organised Private Sector. The questionnaire was administered online, and participants were invited via email and social media. The analysis revealed a significant positive correlation (r = 0.674, p &lt; 0.000) between distributive justice and employees' performance. This indicates that when employees perceive that outcomes and rewards are distributed fairly within the organization, their performance improves. Also, Procedural justice showed an even stronger positive correlation with employees' performance (r = 0.718, p &lt; 0.000). This suggests that when employees believe that the processes and procedures used to make decisions are fair, their performance is significantly enhanced. Interactional justice also had a significant positive correlation with employees' performance (r = 0.681, p &lt; 0.000). The study recommended that organizations can improve employee performance by putting in place fair and transparent remuneration structures, assessing and modifying reward programmes regularly to align them with market norms and employee contributions, and creating recognition initiatives that honour and recognize staff members for their efforts and accomplishments.

Optical Coherence Tomography Angiography Analysis of Peripapillary Choroidal Microvascular Density in normal-tension Glaucoma and Primary open-angle Glaucoma.

Glaucoma patients had a reduction in the inner annulus peripapillary choroidal microvascular density (PCMD) that became worse as the glaucoma severity progressed, which might provide new evidence supporting the vascular theory. To compare PCMD among normal-tension glaucoma (NTG), primary open-angle glaucoma (POAG), and healthy controls using optical coherence tomography (OCT) angiography (OCTA). The study included 40 POAG, 25 NTG, and 33 healthy controls. All subjects underwent OCT and OCTA testing. Inner annulus and outer annulus PCMD, as well as peripapillary vessel density (VD), was calculated. One-way analysis of variance was used to compare the vascular parameters of the three groups. Pearson correlation analysis or Spearman correlation test was used to evaluate the correlation between PCMD and glaucomatous severity factors. The spatial positional relationship between PCMD and corresponding peripapillary retinal nerve fiber layer (RNFL) thickness and visual field (VF) mean deviation (MD) was also assessed. The average and four quadrants of the inner annulus PCMD and peripapillary VD in the two glaucomatous groups were significantly lower than in normal eyes (P<0.05). Strong correlations were found between inner annulus PCMD and VF MD, peripapillary VD, and RNFL in POAG patients. Similarly, the inner annulus PCMD in NTG patients was strongly correlated with peripapillary VD and RNFL (all r>0.5). Strong positional correlations were found between inner superior quadrantal PCMD and RNFL thickness in both POAG and NTG patients (r=0.566, r=0.731, respectively). Likewise, inner inferior quadrantal PCMD exhibited a strong correlation with RNFL thickness in POAG patients (r=0.608). Strong positional correlations were also found between inner superior PCMD and VF MD in both POAG and NTG patients (r=0.589, r=0.622, respectively). Inner inferior PCMD exhibited a moderate correlation with VF MD in both POAG and NTG patients (r=0.487, r=0.440, respectively). The study found that the inner annulus PCMD decreased to varying degrees in NTG and POAG patients. The inner annulus PCMD was closely related to the structural and visual function parameters of glaucoma in both NTG and POAG. Furthermore, inner PCMD demonstrated a spatial correlation with corresponding RNFL thickness and VF MD.

Results of electrocardiography in children born at very early preterm birth

Background. Children born at extremely early preterm birth (EPL) are at high risk of developing cardiovascular diseases, including heart rhythm disorders (HRDs) and conduction disorders throughout life.Objective: To study electrocardiographic features in children of the first year of life born at term SPR.Materials and methods. The main group consisted of 51 children born at term. Depending on body weight, the main group was divided into 2 subgroups. Subgroup 1 consisted of children weighing 500-750 g (n=15). Subgroup 2 — children weighing 751 g or more (n=36). The comparison group included 28 children born at a gestational age of 32-36 weeks. Children were examined at the ages of 6 and 12 months. Electrocardiography was performed on children at rest in 12 standard leads with a paper tape speed of 50 mm/sec. Analysis of ECG indicators was carried out using a Sicard electrocardiograph from Siemens AG, according to generally accepted methods.Results and discussion. In children born at gestational age during 1 year of life, clinical manifestations of impaired functional state of the cardiovascular system were observed in the form of vegetative-vascular dysfunction, NSR, and changes in the characteristics of heart sounds. According to the ECG results, NSR was identified in the form of sinus arrhythmia, sinus tachy- and bradycardia, extrasystole, atrial rhythm, pacemaker migration, supraventricular paroxysmal tachycardia, WPW syndrome, long QT interval syndrome, which amounted to 86.7% of cases in children of subgroup 1, in children of the 2nd subgroup 82.2% and 60.7% in children of the comparison group. A direct strong correlation has been established between the clinical manifestations of autonomic dysfunctions at the age of 12 months and the frequency of identified dysfunctions. By 12 months of life, the number of children with sinus bradycardia, sinus arrhythmia and ectopic rhythm increases. There is no positive trend in the frequency of detection of ECG phenomena during the first year of life.Conclusion. Children born at very early preterm birth require cardiac monitoring, including blood pressure measurement, electrocardiography and the development of personalized clinical follow-up programs.

Bioinformatics and experimental validation were combined to explore lactylation-related biomarkers in HBV-associated acute liver failure.

Currently, hepatitis B virus-related acute liver failure (HBV-ALF) has limited treatment options. Studies have shown that histone lactylation plays a role in the progression of liver-related diseases. Therefore, it is essential to explore lactylation-related gene (LRGs) biomarkers in HBV-ALF to provide new information for the treatment of HBV-ALF. Two HBV-ALF-related datasets (GSE38941 and GSE14668) and 65 LRGs were used. First, the differentially expressed genes (DEGs) were derived from differential expression analysis, the key module genes from weighted gene co-expression network analysis; and LRGs were used to intersect to obtain the candidate genes. Subsequently, the feature genes obtained from least absolute shrinkage and selection operator regression analysis and support vector machine analysis were intersected to obtain the candidate key genes. Among them, genes with consistent and significant expression trends in both GSE38941 and GSE14668 were used as biomarkers. Subsequently, biomarkers were analyzed for functional enrichment, immune infiltration, and sensitive drug prediction. In this study, five candidate genes (PIGM, PIGA, EGR1, PIGK, and PIGL) were identified by intersecting 6461 DEGs and 2496 key module genes with 65 LRGs. We then screened four candidate key genes from the machine learning algorithm, among which PIGM and PIGA were considered biomarkers in HBV-ALF. Moreover, the results of enrichment analysis showed that the significant enrichment signaling pathways for biomarkers included allograft rejection and valine, leucine, and isoleucine degradation. Thereafter, 11 immune cells differed significantly between groups, with resting memory CD4+ T cells having the strongest positive correlation with biomarkers. Methylphenidate hydrochloride is a potential therapeutic drug for PIGM. Two genes, PIGM and PIGA, were identified as biomarkers related to LRGs in HBV-ALF, providing a basis for understanding HBV-ALF pathogenesis.

Research Note: Dynamics of black grouse (Tetrao tetrix) infestation with various Eimeria species

The black grouse (Tetrao tetrix) is an endangered species facing challenges in breeding and reintroduction programs, including parasitic infestations. This study aimed to assess natural infestations by various Eimeria species and infestation dynamics in female, male, and young black grouse kept in a stationary aviary. Faecal samples were collected from adult grouses between April and the time of chicks' hatching and rearing (September). Faecal samples from young birds were collected from the hatching for a period of 1 year. The prevalence of Eimeria spp. was determined by a qualitative method (Fulleborn's flotation) and a quantitative method (McMaster's method with Raynaud's modification). The following Eimeria species were identified: E. lyruri, E. nadsoni and E. nonbrumpti. The average percentages of Eimeria spp. in the cock were 80.52%, 9.27%, and 10.21%, respectively; in the hen, they were 86.19%, 9.28%, and 4.53%, respectively; in the young black grouses they were 84.60%, 9.34% and 6.06%, respectively. The highest E. lyruri infestation was observed in the cock in June (144227 OPG) and July (129365 OPG). In the hen, the infestation intensity increased in May (304302 OPG) and then decreased in June (39583 OPG). Furthermore, an additional increase was observed in July (216533 OPG). Two increases in infestation intensity were also observed in young birds, with peaks in January (91387 OPG) and July (126178 OPG). A positive strong correlation was identified between Eimeria spp. in the cock and the young birds. A statistically significant positive correlation was identified in the hen between E. lyruri and E. nadsoni. No correlation was demonstrated between the infestation intensity and the age of the birds or season of the year in all the grouses under study. Despite some attempts, a comprehensive approach to the issue of coccidiosis in the black grouse as a disease that may affect the success of reintroduction has yet to be established. It seems crucial to monitor the level of Eimeria spp. invasion, and the proposed faecal sampling scheme is an important tool for achieving this goal.