Strong Individual Preferences Research Articles

Performance on inhibitory tasks does not relate to handedness in several small groups of Callitrichids.

Brain lateralization, a trait ubiquitous in vertebrates and invertebrates, refers to structural differences between the left and right sides of the brain or to the left and right sides controlling different functions or processing information in different ways. Many studies have looked into the advantages of lateralized brains and discovered that cerebral lateralization confers a fitness advantage. Enhancing cognitive ability has been proposed as one of the potential benefits of the lateralized brain, however, this has not been widely validated. In this study, we investigated the handedness of 34 subjects from four groups of Callitrichids, as well as their performance in two inhibitory control tasks (the revised A-not-B task and the cylinder task). The subjects had strong individual hand preferences, and only a few zoo-born individuals were ambidextrous. Sex and generation influence the strength of hand preference. In the cylinder task, the subjects showed differences between groups, and the performance of the second-generation was better than that of the first-generation. We found that neither the strength of hand preferences (ABS-HI) or direction of hand preferences (HI) was linked with success on the two inhibitory tasks. That is, we were unable to support the enhanced cognitive function hypothesis. We believe that individual ontogeny and the type of cognitive task have an impact on the support of this hypothesis. The advantages of lateralized brain may be reflected in tests that require multiple cognitive abilities.

Flow of Light: Balancing Directionality and CCT in the Office Environment

ABSTRACT Human perception and vision have evolved in response to dynamic daylight, a combination of radiation from direct sunlight and diffuse skylight, which has created a flow of variations in light, in terms of direct:diffuse distribution, intensities and spectrum. This study investigates the qualities of the flow of light in an office after adding ceiling-mounted spotlights (32° tilt angle) to traditional diffuse ceiling panels. The intention is to create a flow of task light – a light-zone at each work-plane – complementing the directionality of the natural daylight inflow from the windows. An experiment was carried out in an office, in two parts. Four ratios of direct:diffuse light were tested by 30 people. Then one ratio was tested in five combinations of high, neutral and low color temperatures by 15 people in two daylight situations: overcast and clear sky. The visual light quality and perceived atmosphere of the office environment was tested through questionnaires, reaction cards and semi-structured interviews. The direct flow of light is recommended to be more than 15% of the total illuminance at the work-plane to provide the distinct visual appearance of modeling and a cozier atmosphere, which is preferable for socializing, and less than 45% to avoid glare and high contrast for visual tasks. Direct warm and diffuse cool lighting were perceived as the most natural but were not always preferred. There is an indication of slight preference for cooler ambient lighting in clear sky situations and warmer ambient lighting in overcast situations. Especially the preference in relation to sky conditions needs to be further investigated. A field study will implement these findings in a double dynamic lighting concept responding to daylight level and sky character. Strong individual preferences for combinations of color temperatures was identified, this open up new research areas for personalized flows of light in future dynamic lighting designs.

Quality Comparison of 3 Tesla multiparametric MRI of the prostate using a flexible surface receiver coil versus conventional surface coil plus endorectal coil setup

PurposeTo subjectively and quantitatively compare the quality of 3 Tesla magnetic resonance imaging of the prostate acquired with a novel flexible surface coil (FSC) and with a conventional endorectal coil (ERC).MethodsSix radiologists independently reviewed 200 pairs of axial, high-resolution T2-weighted and diffusion-weighted image data sets, each containing one examination acquired with the FSC and one with the ERC, respectively. Readers selected their preferred examination from each pair and assessed every single examination using six quality criteria on 4-point scales. Signal-to-noise ratios were measured and compared.ResultsTwo readers preferred FSC acquisition (36.5–45%) over ERC acquisition (13.5–15%) for both sequences combined, and four readers preferred ERC acquisition (41–46%). Analysis of pooled responses for both sequences from all readers shows no significant preference for FSC or ERC. Analysis of the individual sequences revealed a pooled preference for the FSC in T2WI (38.7% vs 17.8%) and for the ERC in DWI (50.9% vs 19.6%). Patients’ weight was the only weak predictor of a preference for the ERC acquisition (p = 0.04). SNR and CNR were significantly higher in the ERC acquisitions (p<0.001) except CNR differentiating tumor lesions from benign prostate (p=0.1).ConclusionAlthough readers have strong individual preferences, comparable subjective image quality can be obtained for prostate MRI with an ERC and the novel FSC. ERC imaging might be particularly valuable for sequences with inherently lower SNR as DWI and larger patients whereas the FSC is generally preferred in T2WI. FSC imaging generates a lower SNR than with an ERC.

Evidence of an emerging female preference for an artificial male trait and the potential for spread via mate choice copying in Poecilia latipinna

AbstractThe initial purpose of the project described herein was to assess the preference of female Poecilia latipinna for an artificial novel male trait—an orange‐colored distal fringe added to the caudal fin of an otherwise wild‐type conspecific. Analysis of the preliminary data revealed consistent individual differences in the strength of female preference for either orange‐tailed or wild‐type males. This finding inspired the study's second aim—to evaluate whether the preference for orange‐tailed males observed among a subset of females could spread via mate choice copying to others in the population that initially preferred wild‐type males. Two experiments and a control were conducted wherein females were simultaneously presented with an orange‐tailed and a wild‐type dummy male using a standard dichotomous choice design. In the first experiment, female preference was assessed on two separate occasions in order to characterize the variability and consistency in preference for orange‐tailed versus wild‐type males. The second experiment addressed mate choice copying: Female preference was again assessed on two separate occasions, but involved pairing a model female with the non‐preferred male for a period of time between preference tests. A third set of control tests were conducted using the same protocol as the copying experiment except that subject females were unable to see the model paired with the non‐preferred male. Results showed that, although females collectively preferred neither the orange‐tailed nor the wild‐type dummy male in the first round of preference tests, the majority showed relatively strong individual preferences. The subset of females that preferred the orange‐tailed over the wild‐type male in the first round of testing all maintained their preferences in the second round whether or not they had observed a model in association with the non‐preferred wild‐type male between tests. However, females that preferred the wild type over the orange male in the first round of testing copied the model's choice of the non‐preferred orange‐tailed male in their second round of preference testing. These results highlight the importance of recognizing the likelihood that only a subset of females will express a preference as it first emerges within a population. In such instances, the preference may not be detected at the population level—a point frequently overlooked in studies of mate choice. Additionally, these data highlight the importance of assessing the preferences of individual females and their capacity to drive evolutionary change within populations. Lastly, this study offers evidence of a possible mechanism by which a novel male trait might spread via mate choice copying by exploiting an emerging sensory bias within a subset of females in the population.

The importance of operator knowledge in evaluating virtual reality cue fidelity

Research, development, testing, and operator training of large agricultural harvesting equipment has become increasingly expensive and complex. Operational simulators can offset these costs, but it is critical to evaluate the fidelity of the simulator experience to ensure that it will lead to operator behaviors that match those in the real world. This research describes a validation process for new visual cues within simulators and focuses on the presentation and fidelity of cues in a combine harvest simulator. The fully functional immersive combine simulator in this work provides a mixed-reality interface that combines a physically accurate operator interface with displays of virtual reality (VR) combine header and grain. Grain combine operators participated to assess how well they perceived the VR cues as representing actual field and crop activity. Results showed that operators successfully identified 85% of the visual cues in the combine simulator and recognized when these cues indicated machine settings adjustment needs but that operators' ability to choose the correct action to take correlated with their knowledge of the combine. Results also showed wide variation in the number of the grain combine’s head reel adjustments made by operators, likely reflecting strong individual preferences or habits around reel adjustment. Operators' number of adjustment interactions with the reel was also significantly correlated with the number of correct actions chosen, suggesting that careful attention to the reel is related to good farming performance. This research demonstrates the importance of taking operator knowledge and preferences into account when designing new agricultural products and offers a systematic method of validating cues within an agricultural simulator.

Redistributive Preferences and Protests in Latin America

This article analyzes the role of individual redistributive preferences on protest participation. The article focuses on Latin America, a region that has experienced substantial protests and demonstrations in the last decade, making use of individual-level data on redistributive preferences and protest participation collected across eighteen countries in 2010, 2012, and 2014. The results show evidence for an association between strong individual preferences for redistribution and participation in protests motivated by the low quality of services and institutions, failures to reduce corruption, and perceived lower standards of living. The results are robust to alternative estimators, samples, and model specifications and not affected by endogeneity concerns.

What about the others? Consensus and equilibria in the presence of self-interest and conformity in social groups

This paper analyzes the decision-making processes of heterogeneous agents, when both individual preferences and group actions are taken into account. Under the assumptions of certain topologies of interactions and assuming cognitive and informational restrictions, an agent-based model is introduced to analyze the evolution of decisions over time. The results of the simulations show how social pressures can determine the relationship between individual and social preferences. Societies whose agents have strong individual preferences have outcomes with fragmentation processes that generates a higher number of groups. A minor importance of the individual preferences, results in a smaller proportion of individuals maximizing their individual utility. As well, the quantity of options available and the initial proportion of each alternative are significant variables to determine the proportion of individuals selecting a particular option. In addition, the study analyzes the existence of equilibrium of the dynamical system. To this aim, the notion of metastable equilibria is introduced and linked to the dynamic analysis.

Consensus and Equilibria in the Presence of Self-Interest and Conformity in Social Groups

This paper analyses the decision-making processes of heterogeneous agents, when both individual preferences and group actions are taken into account. Under the assumptions of certain topologies of interactions and assuming cognitive and informational restrictions, an agent-based model is introduced to analyze the evolution of decisions over time. The results of the simulations show how social pressures can determine the relationship between individual and social preferences. Societies whose agents have strong individual preferences have outcomes with fragmentation processes that generates a higher number of groups. A minor importance of the individual preferences, results in a smaller proportion of individuals maximizing their individual utility. As well, the quantity of options available and the initial proportion of each alternative are significant variables to determine the proportion of individuals selecting a particular option. In addition, the study analyses the existence of equilibrium of the dynamical system. To this aim, the notion of metastable equilibria is introduced and linked to the dynamic analysis.

Variations in Burn Excision and Grafting: A Survey of the American Burn Association.

It is unknown whether variations in burn care affect outcomes or affect the success of emerging therapeutics. The purpose of this study was to assess burn surgeons' preferences in excision and grafting to determine if surgical technique affects outcomes. A 71-item survey evaluating skin grafting techniques and preferences was emailed to members of the American Burn Association in July and August 2015. The survey was anonymous and voluntary. Relationships between variables were evaluated using Fisher's exact test. A P-value of ≤.05 was deemed statistically significant. The survey was sent to 607 burn surgeons, and the response rate was 24%. Clinical judgment is the most widely used method to determine depth of injury. Surgeons who practice in the United States and surgeons who are board certified in general surgery are more likely to determine depth of the burn based on clinical judgment alone (P < .001). Fifty-six percent of surgeons will perform excision as early as postburn day 1 and 73% will excise greater than 20% TBSA in one setting. Surgeons at centers with bed number of ≤10 (P = .024) or surgeons with board certification in plastic surgery (P = .008) are more likely to excise deep partial-thickness burns with an attempt to retain viable dermis. Geographic location, board certification, and burn unit size all contribute to variations in practice. Strong individual preferences make standardization of therapies challenging and may affect the success of new technologies. Burn surgery continues to be an art as much as a science, and accurate documentation of techniques and outcomes is essential for optimizing successes and documenting failures of new treatment methods.

Smartphone-Based System for Learning and Inferring Hearing Aid Settings.

Previous research has shown that hearing aid wearers can successfully self-train their instruments' gain-frequency response and compression parameters in everyday situations. Combining hearing aids with a smartphone introduces additional computing power, memory, and a graphical user interface that may enable greater setting personalization. To explore the benefits of self-training with a smartphone-based hearing system, a parameter space was chosen with four possible combinations of microphone mode (omnidirectional and directional) and noise reduction state (active and off). The baseline for comparison was the "untrained system," that is, the manufacturer's algorithm for automatically selecting microphone mode and noise reduction state based on acoustic environment. The "trained system" first learned each individual's preferences, self-entered via a smartphone in real-world situations, to build a trained model. The system then predicted the optimal setting (among available choices) using an inference engine, which considered the trained model and current context (e.g., sound environment, location, and time). To develop a smartphone-based prototype hearing system that can be trained to learn preferred user settings. Determine whether user study participants showed a preference for trained over untrained system settings. An experimental within-participants study. Participants used a prototype hearing system-comprising two hearing aids, Android smartphone, and body-worn gateway device-for ∼6 weeks. Sixteen adults with mild-to-moderate sensorineural hearing loss (HL) (ten males, six females; mean age = 55.5 yr). Fifteen had ≥6 mo of experience wearing hearing aids, and 14 had previous experience using smartphones. Participants were fitted and instructed to perform daily comparisons of settings ("listening evaluations") through a smartphone-based software application called Hearing Aid Learning and Inference Controller (HALIC). In the four-week-long training phase, HALIC recorded individual listening preferences along with sensor data from the smartphone-including environmental sound classification, sound level, and location-to build trained models. In the subsequent two-week-long validation phase, participants performed blinded listening evaluations comparing settings predicted by the trained system ("trained settings") to those suggested by the hearing aids' untrained system ("untrained settings"). We analyzed data collected on the smartphone and hearing aids during the study. We also obtained audiometric and demographic information. Overall, the 15 participants with valid data significantly preferred trained settings to untrained settings (paired-samples t test). Seven participants had a significant preference for trained settings, while one had a significant preference for untrained settings (binomial test). The remaining seven participants had nonsignificant preferences. Pooling data across participants, the proportion of times that each setting was chosen in a given environmental sound class was on average very similar. However, breaking down the data by participant revealed strong and idiosyncratic individual preferences. Fourteen participants reported positive feelings of clarity, competence, and mastery when training via HALIC. The obtained data, as well as subjective participant feedback, indicate that smartphones could become viable tools to train hearing aids. Individuals who are tech savvy and have milder HL seem well suited to take advantages of the benefits offered by training with a smartphone.

Self-fitting hearing aids reveal strong individual preferences in noisy rooms

Noisy restaurants are among the most challenging listening situations for listeners with hearing loss, but little data are available to optimize hearing aids for noisy situations. In addition, evidence suggests that listeners are less satisfied with hearing devices in noisy listening environments. New technology from EarMachine(c) allows for individuals with hearing loss to self-adjust hearing aid amplification parameters. Self-adjustment technology can provide data to empirically answer questions about listener preferences in noise. Results from 30 listeners demonstrated self-selected gain profiles that reveal very large individual preferences that are not well predicted by age, gender, or hearing loss. These results indicate that there are strong preferences for listening in noisy rooms that are not yet well understood. [Funding provided by NIDCD R01 DC013267.]

Cash only? Unveiling preferences for a PES contract through a choice experiment in Chiapas, Mexico

Payments for Ecosystem Services (PES) have been promoted worldwide as a means to incentivise biodiversity, forest conservation and sustainable forest management. Mexico has been at the forefront of PES implementation since 2003, and the country has now more than 2.6 million hectares under a variety of PES contracts. In this article, we perform a choice experiment with a group of 82 community forest owners who are receiving a payment for providing biodiversity-related ecosystem services in the state of Chiapas. Considering possible future evolutions in contract design, we explore individuals preferences over contract characteristics including who is involved in deciding the parcels to be included in the contract, the type of technical intermediary, the level of payment and the type of incentive (either in individual cash payments or in collective investments). Our results show a reluctance to decide collectively on issues related to forest conservation, as well as on dedicating a share of payments to collective projects. We find strong individual preferences for payments in cash, even when the amount of monetary compensation is lower than in the existing PES contract, and we show that most participants value positively the help received by external service providers in PES implementation. An analysis of preference heterogeneity suggests that community leaders play a key role in moderating individual preferences and enhancing participation structured around working groups. We thus argue that the willingness to accept a PES program is greatly dependent on local governance factors. As such, exploring ways for PES contractual options to match the diversity of local conditions and individual preferences – allowing a modular allocation of PES into cash or investment on an individual or collective basis- could further stimulate participation in Mexico’s PES programme.

Hand preference during bimanual coordinated task in northern pig-tailed macaques Macaca leonina.

In humans, handedness is one defining characteristic regardless of cultures and ethnicity. Population-level right handedness is considered to be related with the evolution of left hemisphere for manual control and language. In order to further understand evolutionary origins of human cerebral lateralization and its behavioral adaptation, standardized measures on hand preference are required to make reliable comparison in nonhuman primate species. In this study, we present the first evidence on hand preference during bimanual coordinated tasks in northern pig-tailed macaques Macaca leonina. The classical TUBE task was applied to examine hand preference among nine individuals from Tianjin Zoo of China. We recorded and made analysis on both frequency and bout data on manual laterality. The results consistently show that subjects displayed strong individual hand preferences, whereas no significant group-level handedness was found. There were no sex and age significant differences on both direction and strength of hand preference. The M. leonina preferred to use the index finger to extract the baited food inside the tube. Our findings fill the knowledge gap on primate handedness, and efficiently affirm the robustness of the TUBE task as one efficient measure of hand preference in primates.

High-Resolution 3-T Endorectal Prostate MRI: A Multireader Study of Radiologist Preference and Perceived Interpretive Quality of 2D and 3D T2-Weighted Fast Spin-Echo MR Images.

The goal of this study was to compare the perceived quality of 3-T axial T2-weighted high-resolution 2D and high-resolution 3D fast spin-echo (FSE) endorectal MR images of the prostate. Six radiologists independently reviewed paired 3-T axial T2-weighted high-resolution 2D and 3D FSE endorectal MR images of the prostates of 85 men in two sessions. In the first session (n = 85), each reader selected his or her preferred images; in the second session (n = 28), they determined their confidence in tumor identification and compared the depiction of the prostatic anatomy, tumor conspicuity, and subjective intrinsic image quality of images. A meta-analysis using a random-effects model, logistic regression, and the paired Wilcoxon rank-sum test were used for statistical analyses. Three readers preferred the 2D acquisition (67-89%), and the other three preferred the 3D images (70-80%). The option for one of the techniques was not associated with any of the predictor variables. The 2D FSE images were significantly sharper than 3D FSE (p < 0.001) and significantly more likely to exhibit other (nonmotion) artifacts (p = 0.002). No other statistically significant differences were found. Our results suggest that there are strong individual preferences for the 2D or 3D FSE MR images, but there was a wide variability among radiologists. There were differences in image quality (image sharpness and presence of artifacts not related to motion) but not in the sequences' ability to delineate the glandular anatomy and depict a cancerous tumor.

Why do - or don't - patients with urinary tract infection participate in a clinical trial? A qualitative study in German family medicine.

Background: Insufficient patient recruitment can impair the conduct of clinical trials substantially, not least because a significant number of eligible patients decline trial participation. Though barriers and motivational factors have been worked out for patients with cancer or chronic diseases, little is known about primary care patients’ perceptions towards trial participation when visiting their family practitioner (FP) with acute uncomplicated conditions. This study aims to assess primary care patients’ motivation and barriers to participate in trials, and to identify factors that optimize patient recruitment in future trials.Methods: This study was embedded in a drug trial comparing two treatment strategies for women with uncomplicated urinary tract infection in primary care. Semi-structured telephone interviews both with trial participants and decliners were conducted. The interview guideline focused on patients’ personal motivational or hampering factors. Further topics were study theme, FPs’ role, randomization, trial procedures, and potential motivational factors or barriers presumed to be relevant for other patients. Transcripts were analyzed by summarizing content analysis.Results: 20 interviews with trial participants and 5 interviews with trial decliners were conducted. Results show various reasons for trial participation from three categories: personal aspects, trial related aspects and patient-physician-relationship. A relevant trial topic and perceived personal benefit promotes participation as well as the wish to support research in general. Additionally, a maximum of safety concerning symptom relief reassures patients significantly. Trust in the FP plays also an important role in the decision process. Trial decliners show strong individual treatment preferences, which, together with individual reasons, lead to trial refusals.Conclusions: To optimize recruitment conditions for further clinical trials on acute and common conditions in family medicine, the following key issues should be considered: emphasizing patients’ personal benefit, featuring patient relevant trial topics, providing a maximum of safety, keeping effort by trial procedures comfortable.

Commentary on Forsyth et al. (2014): Subgroup differences in post‐release mortality—implications for access to diverse and effective treatments

In their cohort study of more than 42 000 individuals released from prisons in Queensland, Australia, Forsyth and colleagues 1 extend the existing literature on post-release health outcomes in two important ways. First, the study highlights alcohol as an important cause of death among indigenous people from prison. International studies have demonstrated an early elevated risk of drug-related death after release from prison 2, 3. However, compared to drugs, alcohol use as a contributor to poor post-release health outcomes has received relatively less attention by researchers and policymakers. As highlighted by the authors, interventions that focus exclusively on reducing the complications of drug use may not adequately address the needs of many at risk for complications of alcohol use. Secondly, time trends in mortality after release from prison vary by cause of death and population. For instance, Forsyth and colleagues show no clear early peak in alcohol-related deaths among non-indigenous people and only a small early elevation in alcohol-related deaths in indigenous people after release from prison. Differences in substance use patterns, economic circumstances, community and family support and access to community services vary by culture, ethnicity, gender and regional context. Interventions to address post-release morbidity and mortality may show the most benefit when tailored to the cultural backgrounds of people returning from prison and the specific contexts to which they return. Unfortunately, there is a notable paucity of evidence-based, effective interventions designed to prevent post-release morbidity and mortality. It is critical to develop and test novel interventions, particularly tailored interventions, to prevent poor outcomes among individuals coming out of prisons. It would be expected that the benefits of interventions may be heterogeneous across medical diagnoses, mental health conditions, substances involved, time relative to release and populations studied. Epidemiological findings on post-release mortality provide some guidance on the diversity of potential health outcomes to consider, when they should be assessed relative to release and in which populations of people leaving prisons. In the meantime, there are many evidence-based treatments for substance use disorders that are systematically denied to individuals in prison and to which those leaving prisons have limited access. While enforced abstinence may be relatively feasible in prison, this approach does not prepare people well for the post-release environment and life in the community. In the community, individuals are faced with numerous triggers to use alcohol and drugs 4. Pharmacologically supported treatments for alcohol, tobacco and other drugs should be made available to those who need and want them in prisons and during the transition back to the community. It is critical that people in prisons have access to a broad range of effective treatment options, given that they may have previously failed some, have experienced adverse effects of others and may have strong individual (or cultural) preferences for the types of treatment they want. Decisions about which treatments are available to people with criminal justice involvement cannot be made based on long-standing biases against medication-assisted treatment; nor should they be made based on simplistic cost estimates that fail to account for the high cost of incarceration and uncontrolled substance use disorders. People involved in the criminal justice system, often as a result of problems with alcohol and drugs, are the people who need the very best treatment options we have to offer—but are the least likely to get them 5-7. At the same time, community access to evidence-based treatment is one approach to preventing incarceration in the first place. Without universal access to evidence-based addiction treatment in the community, having a truly ethical justice system is out of reach. None.

Surgical Approaches to Invasive Adenocarcinoma of the Gastroesophageal Junction

Despite a plethora of data, the optimal surgical approach to invasive adenocarcinoma of the gastroesophageal (GE) junction remains controversial. To quote Dr. Valerie Rusch, "Strong individual preferences and some degree of surgical mystique often govern the selection of operation for resection of GE junction adenocarcinomas."1 The fırst of these controversies is whether the optimal open surgical approach should be via the transabdominal, transthoracic (two-incision Ivor Lewis or three-incision McKeown), or transhiatal route. Proponents of the transthoracic or transhiatal routes have voiced strong opinions on the potential advantages and disadvantages of each approach (Table 1). It is clear from most large retrospective series that, in experienced hands, excellent results can be achieved by either approach. The principal advantage of the transthoracic route is the ability to perform a radical mediastinal lymphadenectomy en bloc with the primary tumor, the theory being that a more aggressive lymph node dissection would be associated with an improved long-term outcome. To date, however, this association of a more aggressive lymphadenectomy with improved outcome has remained elusive in most gastrointestinal malignancies, including esophageal cancer. Proponents of the transhiatal approach cite similar lymph node retrieval rates, the potential for lower short-term morbidity, and the potential for similar long-term outcomes.2 With the advent of newer technology, the controversy regarding the optimal surgical approach to adenocarcinoma of the GE junction has evolved in yet another direction, with proponents of a minimally invasive approach, citing even lower perioperative morbidity and mortality, again with comparable or even superior long-term oncologic results.

Surgical Approaches to Invasive Adenocarcinoma of the Gastroesophageal Junction

Despite a plethora of data, the optimal surgical approach to invasive adenocarcinoma of the gastroesophageal (GE) junction remains controversial. To quote Dr. Valerie Rusch, "Strong individual preferences and some degree of surgical mystique often govern the selection of operation for resection of GE junction adenocarcinomas."1 The fırst of these controversies is whether the optimal open surgical approach should be via the transabdominal, transthoracic (two-incision Ivor Lewis or three-incision McKeown), or transhiatal route. Proponents of the transthoracic or transhiatal routes have voiced strong opinions on the potential advantages and disadvantages of each approach (Table 1). It is clear from most large retrospective series that, in experienced hands, excellent results can be achieved by either approach. The principal advantage of the transthoracic route is the ability to perform a radical mediastinal lymphadenectomy en bloc with the primary tumor, the theory being that a more aggressive lymph node dissection would be associated with an improved long-term outcome. To date, however, this association of a more aggressive lymphadenectomy with improved outcome has remained elusive in most gastrointestinal malignancies, including esophageal cancer. Proponents of the transhiatal approach cite similar lymph node retrieval rates, the potential for lower short-term morbidity, and the potential for similar long-term outcomes.2 With the advent of newer technology, the controversy regarding the optimal surgical approach to adenocarcinoma of the GE junction has evolved in yet another direction, with proponents of a minimally invasive approach, citing even lower perioperative morbidity and mortality, again with comparable or even superior long-term oncologic results.

Handedness in nature: first evidence on manual laterality on bimanual coordinated tube task in wild primates.

Handedness is a defining feature of human manual skill and understanding the origin of manual specialization remains a central topic of inquiry in anthropology and other sciences. In this study, we examined hand preference in a sample of wild primates on a task that requires bimanual coordinated actions (tube task) that has been widely used in captive primates. The Sichuan snub-nosed monkey (Rhinopithecus roxellana) is an arboreal Old World monkey species that is endemic to China, and 24 adult individuals from the Qinling Mountains of China were included for the analysis of hand preference in the tube task. All subjects showed strong individual hand preferences and significant group-level left-handedness was found. There were no significant differences between males and females for either direction or strength of hand preference. Strength of hand preferences of adults was significantly greater than juveniles. Use of the index finger to extract the food was the dominant extractive-act. Our findings represent the first evidence of population-level left-handedness in wild Old World monkeys and broaden our knowledge on evaluating primate hand preference via experimental manipulation in natural conditions.

Manual Laterality for Simple Reaching and Bimanual Coordinated Task in Naturalistic Housed Pan troglodytes

Researchers have shown renewed interest in the study of manual lateralization in chimpanzees. Currently there is no consensus confirming the presence or absence of manual dominance at a species level, mainly for populations in the wild and in semicaptivity. We aimed to evaluate the manual laterality in a group of chimpanzees in an intermediate setting (semicaptivity) via 2 tasks: one simple and unimanual (simple reaching) and the other complex and bimanual (tube task). We replicated the same experiments from Hopkins in a new and different sample of chimpanzees. In simple reaching, the hand is used to gather food and the type of grip and the posture are evaluated. The tube task assesses the hand used to extract food from the tube and the method of extraction (digital or instrumental). Through the handedness index we observed that the subjects show clear and strong individual preferences for both tasks (100% lateralized subjects in the tube task; 86% in simple reaching), although we did not detect population preferences for any of the tasks. However, considering both tasks jointly (multiple evaluation), it was possible to detect, for the first time, skilled manual dominance at a group level in semicaptive chimpanzees in one multitask index and borderline significance in a second multitask index.