Strong Coupling Conditions Research Articles

Agonist stimulation at human μ opioid receptors in a [35S]GTPγS incorporation assay: observation of “bell-shaped” concentration–response relationships under conditions of strong receptor G protein coupling

Context: The appearance of “bell”- (or “inverted U”-) shaped agonist concentration–response curves (CRCs) in in vitro pharmacological experiments is a frequently observed but poorly communicated phenomenon. In the context of G protein coupled receptor research, it is commonly attributed to the recruitment of secondary targets or to desensitization or feedback processes, but the concrete background of these observations often remains intriguing. Objective: Here, we addressed the subject of bell-shaped agonist CRCs at the µ opioid receptor (µOR) by testing the impact of experimental conditions favoring G protein coupling. Methods: G protein activation by recombinant human µORs heterologously expressed in CHO cells was assessed in [35S]GTPγS binding assays using the opioid ligands DAMGO, morphine, fentanyl and naloxone. Experimental conditions were varied by changing the NaCl (10–300 mM) and the GDP concentration (0.3–30 µM). Results: Both the sodium and the GDP concentration were inversely related to G protein coupling, as evident by an increase in basal [35S]GTPγS incorporation at low sodium and low GDP levels and by the concomitant appearance of the partial agonist activity of the µOR antagonist, naloxone. Bell-shaped CRCs were observed for the efficacious agonists DAMGO, fentanyl and morphine, and this phenomenon was promoted by low sodium as well as by low GDP concentrations. Conclusion: µOR agonist CRCs show a non-monotonic behavior with a decline of maximal stimulation under conditions of strong receptor-G protein coupling, and this behavior is visible at the level of G protein activation itself.

Whirl speeds of mistuned bladed rotors supported by isotropic stator

As an initial step toward understanding the fully coupled dynamics of mistuned bladed disk-shaft systems, this paper investigates the frequency characteristics of natural whirl speeds associated with the in-plain vibration of a rotating mistuned bladed disk mounted on an isotropic support. Through complex multi-blade coordinate transformation and modulation, a simplistic analysis model describing the essential in-plain whirling behavior of mistuned bladed rotor is derived in a typical form of linear differential equations with time-constant coefficients. By applying ordinary eigenvalue analysis for linear time-invariant systems, the whirl speeds of mistuned bladed rotor are examined for cases of weak and strong inter-blade coupling conditions. The mistuning effect on the whirl speeds of the bladed rotor is then explained by classifying the whirling modes into three types according to their cause of manifestation and the frequency relationship: namely, original, coupled multi-blade, and conjugate whirling modes.

Maximum Energy Efficiency Tracking for Wireless Power Transfer Systems

A method for automatic “maximum energy efficiency tracking” operation for wireless power transfer (WPT) systems is presented in this paper. Using the switched-mode converter in the receiver module to emulate the optimal load value, the proposed method follows the maximum energy efficiency operating points of a WPT system by searching for the minimum input power operating point for a given output power. Because the searching process is carried out on the transmitter side, the proposal does not require any wireless communication feedback from the receiver side. The control scheme has been successfully demonstrated in a two-coil system under both weak and strong magnetic coupling conditions. Experimental results are included to confirm its feasibility.

Controlling photon transport in the single-photon weak-coupling regime of cavity optomechanics

We study the photon statistics properties of few-photon transport in an optomechanical system where an optomechanical cavity couples to two empty cavities. By analytically deriving the one- and two-photon currents in terms of a zero-time-delayed two-order correlation function, we show that a photon blockade can be achieved in both the single-photon strong-coupling regime and the single-photon weak-coupling regime due to the nonlinear interacting and multipath interference. Furthermore, our systems can be applied as a quantum optical diode, a single-photon source, and a quantum optical capacitor. It is shown that this the photon transport controlling devices based on photon antibunching does not require the stringent single-photon strong-coupling condition. Our results provide a promising platform for the coherent manipulation of optomechanics, which has potential applications for quantum information processing and quantum circuit realization.

Optical Response of Hybrid Plasmon–Exciton Nanomaterials in the Presence of Overlapping Resonances

We consider a hybrid plasmon–exciton system comprising a resonant molecular subsystem and three Au wires supporting a dipole mode that can be coupled to a dark mode in controllable fashion by variation of a symmetry parameter. The physics of such a system under strong coupling conditions is examined in detail. It is shown that if two wires supporting the dark mode are covered with molecular layers, the system exhibits four resonant modes for a strong coupling regime due to asymmetry and lifted degeneracy of the molecular state in this case, while upon having molecular aggregates covering the top wire with a dipolar mode, three resonant modes appear. Pump–probe simulations are performed to scrutinize the quantum dynamics and find possible ways to control plasmon–exciton materials. It is demonstrated that one can design hybrid nanomaterials with highly pronounced Fano-type resonances when excited by femtosecond lasers.

Normal-Mode Splitting in the Coupled System of Hybridized Nuclear Magnons and Microwave Photons.

In the weak ferromagnetic MnCO_{3} system, a low-frequency collective spin excitation (magnon) is the hybridized oscillation of nuclear and electron spins coupled through the hyperfine interaction. By using a split-ring resonator, we performed transmission spectroscopy measurements of the MnCO_{3} system and observed avoided crossing between the hybridized nuclear magnon mode and the resonator mode in the NMR-frequency range. The splitting strength is quite large due to the large spin density of ^{55}Mn, and the cooperativity value C=0.2 (the magnon-photon coupling parameter) is close to the conditions of strong coupling. The results reveal a new class of spin systems, in which the coupling between nuclear spins and photons is mediated by electron spins via the hyperfine interaction.

Fano-like resonances in split concentric nanoshell dimers in designing negative-index metamaterials for biological-chemical sensing and spectroscopic purposes.

In this study, we investigated numerically the plasmon response of a dimer configuration composed of a couple of split and concentric Au nanoshells in a complex orientation. We showed that an isolated composition of two concentric split nanoshells could be tailored to support strong plasmon resonant modes in the visible wavelengths. After determining the accurate geometric dimensions for the presented antisymmetric nanostructure, we designed a dimer array that shows complex behavior during exposure to different incident polarizations. We verified that the examined dimer was able to support destructive interference between dark and bright plasmon modes, which resulted in a pronounced Fano-like dip. Observation of a Fano minimum in such a simple molecular orientation of subwavelength particles opens new avenues for employing this structure in designing various practical plasmonic devices. Depositing the final dimer in a strong coupling condition on a semiconductor metasurface and measuring the effective refractive index at certain wavelengths, we demonstrate that each one of dimer units can be considered a meta-atom due to the high aspect ratio in the geometric parameters. Using this method, by extending the number of dimers periodically and illuminating the structure, we examined the isotropic, polarization-dependent, and transmission behavior of the metamaterial configuration. Using numerical methods and calculating the effective refractive indices, we computed and sketched corresponding figure of merit over the transmission window, where the maximum value obtained was 42.3 for Si and 54.6 for gallium phosphide (GaP) substrates.

Impurity Effect of Asymmetric Gaussian Potential Quantum Well Qubit

On the condition of strong electron-LO phonon coupling in an asymmetrical Gaussian potential quantum well (AGPQW) with a hydrogen-like impurity at the origin of the coordinate, we calculate the eigenenergies and the eigenfunctions of the ground and the first excited states (GFES) by using a variational method of Pekar type. A single qubit can be realized in this two-level quantum system. We calculate the time evolution and the change of the coordinate of the electron’s probability density. When the electron is in the superposition state of the GFES, the electron’s probability density oscillates in the AGPQW with a certain period \(T_0 =20.716\) fs. It turns out that due to the presence of the asymmetrical Gaussian potential in the growth direction of the QW, the electron probability density shows a single peak configuration in the coordinate range of \(z>0\), whereas it equals to zero in the range of \(z 0.24\) nm. It has a minimum when \(R=0.24\) nm.

FPGA-Based Implementation of Multiple Modes in Near Field Inductive Communication Using Frequency Splitting and MIMO Configuration

Conventional near field inductive wireless power transfer theory shows that systems suffer from splitting frequency behaviors when strong coupling condition exists between the transmitter and the receiver. However, this characteristic has not been explored for communication. Our analysis demonstrates that the splitting behaviour of frequency creates multiple frequencies that support inductive communication in MIMO configuration. As a result, we implement a binary chirp modulation on an FPGA and validate two channel communication using splitting. This paper introduces the use of chirp signals to spread data and excite inductive MIMO systems. The simulation and experiment show that the splitting frequency depends on a quality factor and the flux coupling condition between the data source and receiver. In other words, the degree of mutual coupling defines the splitting mode. This paper proves that multi-channel communication using splitting can be used for data transmission. The results show that data rates of 50 Mbps or 69 Kbps can be achieved for each channel between the transmitters and receivers when the transmitter and receiver operate at the original resonant frequency of 13.56 MHz or 28 KHz, respectively and the distance between them varies from about 1 cm to 10 cm.

Strong coupling without touching

If an excited atom is put in between highreflectance mirrors, the light emitted by the atom can be bounced back and be re-absorbed and be re-emitted, again and again until the light leaks out of the mirrors or is re-emitted into a wrong direction. This coherent oscillation between atom and light, called vacuum Rabi oscillation, results from interference between two superposition states of the atom and the photon, which have different energies or frequencies, or vacuum Rabi splitting. The vacuum Rabi oscillation and splitting demonstrate the quantum nature of light. They also provide single-photon non-linearity for photonic applications. In recent years, these effects have been considered particularly useful for quantum information processing [1] since the oscillation presents a natural mechanism for information exchange between a stationary quantum bit carried by the atom and a flying quantum bit carried by the photon, making scalable and distributed quantum computing possible. Realization of the vacuum Rabi oscillation and splitting, however, is highly non-trivial. It requires the so-called strong coupling condition, that is, the exchange between the atom and the photon must be faster than the photon leaks out of the space enclosed by the mirrors, i.e. the cavity, and faster than the atom emits the light into a wrong direction. The technique to realize the strong coupling condition is to make the cavity small so that the photon is bounced back more frequently to the atom and to make the mirrors more reflective so that the photon can be bounced more times. That means to decrease the cavity volume V and to increase the quality factor Q. Remarkable progresses have been made to make optical microcavities with small V and high Q, facilitating observation of vacuum Rabi oscillation and splitting in highly dissipative solidstate systems [2,3]. However, there is no systematic method to reduce V/Q—the key factor for realizing strong coupling (see Fig. 1a). The reason appears to be fundamental. When the size of a cavity is made as small as comparable to the light wavelength, small deformation of the cavity would result in large evanescent wave and hence photon leakage [4]. A recent proposal by [5] provides a general solution, using a divide-andconquer strategy. A small cavitywith rela-

Long-distance radiative coupling between quantum dots in photonic crystal dimers

We study the mutual interaction between two identical quantum dots coupled to the normal modes of two-site photonic crystal molecules in a planar waveguide geometry, i.e. photonic crystal dimers. We find that the radiative coupling between the two quantum emitters is maximized when they are in resonance with either the bonding or the antibonding modes of the coupled cavity system. Moreover, we find that such effective interdot coupling is sizable, in the meV range, and almost independent from the cavities distance, as long as a normal mode splitting exceeding the radiative linewidth can be established (strong cavity-cavity coupling condition). In realistic and high quality factor photonic crystal cavity devices, such distance can largely exceed the emission wavelength, which is promising for long distance entanglement generation between two qubits in an integrated nanophotonic platform. We show that these results are robust against position disorder of the two quantum emitters within their respective cavities.

Control of optical properties of hybrid materials with chirped femtosecond laser pulses under strong coupling conditions.

The interaction of chirped femtosecond laser pulses with hybrid materials--materials comprised of plasmon sustaining structures and resonant molecules--is scrutinized using a self-consistent model of coupled Maxwell-Bloch equations. The optical properties of such systems are examined with the example of periodic sinusoidal gratings. It is shown that under strong coupling conditions one can control light transmission using chirped pulses in a spatiotemporal manner. The temporal origin of control relies on chirps non-symmetric in time while the space control is achieved via spatial localization of electromagnetic energy due to plasmon resonances.

All-optical electromagnetically induced transparency using one-dimensional coupled microcavities.

We report the first experimental realization of all-optical electromagnetically induced transparency (EIT) via a pair of coherently interacting SiO2 microcavities in a one-dimensional SiO2/Si3N4 photonic crystal consisting of a distributed Bragg reflector (DBR). The electromagnetic interactions between the coupled microcavities (CMCs), which possess distinct Q-factors, are controlled by varying the number of embedded SiO2/Si3N4 bilayers in the coupling DBR. In case of weak microcavity interactions, the reflectivity spectrum reveals an all-optical EIT resonance which splits into an Autler-Townes-like resonance under condition of strong microcavity coupling. Our results open up the way for implementing optical analogs of quantum coherence in much simpler one-dimensional structures. We also discuss potential applications of CMCs.

Functional Mode Electron-Transfer Theory.

A solid approach has been developed to ascertain the correlation of electron transfer with molecular vibration in a quantitative manner. Specifically, the reaction coordinate is identified by maximizing the linear Pearson's correlation coefficient between atomic displacement and the diabatic energy gap. In the limit of fast molecular vibration, the rates of electron transfer driven by multiple vibrational modes have been derived respectively under the strong and weak vibronic coupling conditions. Our functional mode electron-transfer theory is then justified by investigating the electron transfer of a betaine-30 molecule from its first excited state to its ground state when being solvated in glycerol triacetate. Among the 210 available vibrational modes of betaine-30, only seven are essential to the electron transfer by cumulatively accounting for more than 60% of the total reorganization energy. Because all essential vibrational modes are significantly faster than thermal fluctuation, the electron transfer is primarily driven by intramolecular quantum tunneling. Interestingly, the calculated reaction driving force of 1.95 eV is substantially greater than the reorganization energy of 0.58 eV, placing the reaction in the inverted Marcus region. Nevertheless, a sizable Franck-Condon factor of 1.58 × 10(-3) eV(-1) is still achieved due to the large vibronically weighted zero-point energy of the essential vibrational modes. After determining the electronic coupling strength as 0.14 eV by the constrained density functional theory, the overall electron-transfer rate at 300 K is found to be 0.30 ps(-1), which agrees nearly perfectly with experimental values.

The role of level anti-crossings in nuclear spin hyperpolarization

Nuclear spin hyperpolarization is an important resource for increasing the sensitivity of NMR spectroscopy and MRI. Signal enhancements can be as large as 3–4 orders of magnitude. In hyperpolarization experiments, it is often desirable to transfer the initial polarization to other nuclei of choice, either protons or insensitive nuclei such as 13C and 15N. This situation arises primarily in Chemically Induced Dynamic Nuclear Polarization (CIDNP), Para-Hydrogen Induced Polarization (PHIP), and the related Signal Amplification By Reversible Exchange (SABRE). Here we review the recent literature on polarization transfer mechanisms, in particular focusing on the role of Level Anti-Crossings (LACs) therein.So-called “spontaneous” polarization transfer may occur both at low and high magnetic fields. In addition, transfer of spin polarization can be accomplished by using especially designed pulse sequences. It is now clear that at low field spontaneous polarization transfer is primarily due to coherent spin-state mixing under strong coupling conditions. However, thus far the important role of LACs in this process has not received much attention. At high magnetic field, polarization may be transferred by cross-relaxation effects. Another promising high-field technique is to generate the strong coupling condition by spin locking using strong radio-frequency fields. Here, an analysis of polarization transfer in terms of LACs in the rotating frame is very useful to predict which spin orders are transferred depending on the strength and frequency of the B1 field. Finally, we will examine the role of strong coupling and LACs in magnetic-field dependent nuclear spin relaxation and the related topic of long-lived spin-states.

Lasing and phase transition in atomic system with dressed states

The problem of phase transitions in the system of high-density gas of two-level atoms non-resonantly interacting with a pump field in the presence of optical collisions (OCs) and placed in the cavity is studied. The OCs are considered in the framework of thermalization of atomic dressed state (DS) population. For the case of a strong atom-field coupling condition we analyze the problem of thermodynamic equilibrium superradiant phase transition for the order parameter representing real amplitude of cavity mode and taking place as a result of the atomic DS thermalization process. At the same time such a transition can be connected with condensed (coherent) properties of low branch DS-polaritons occurring in the cavity. Various aspects of non-equilibrium phase transition to laser field generation by using atomic DS levels are studied in detail. It is important that for positive atom-light detuning DS lasing can be obtained in the presence of quasi-equilibrium DS population that corresponds to a true two-level atomic system with inversion in perturbative limit.

Density functional theory calculations of continuum lowering in strongly coupled plasmas

An accurate description of the ionization potential depression of ions in plasmas due to their interaction with the environment is a fundamental problem in plasma physics, playing a key role in determining the ionization balance, charge state distribution, opacity and plasma equation of state. Here we present a method to study the structure and position of the continuum of highly ionized dense plasmas using finite-temperature density functional theory in combination with excited-state projector augmented-wave potentials. The method is applied to aluminium plasmas created by intense X-ray irradiation, and shows excellent agreement with recently obtained experimental results. We find that the continuum lowering for ions in dense plasmas at intermediate temperatures is larger than predicted by standard plasma models and explain this effect through the electronic structure of the valence states in these strong-coupling conditions.

Influences of temperature and impurity on excited state of bound polaron in the parabolic quantum dots

On the condition of strong electron-LO phonon coupling in parabolic quantum dot (QD), the first excited state energy, the excitation energy and the transition frequency between the first excited and the ground states of the bound polaron are calculated by using the linear combination operator and the unitary transformation methods. The variation of the above quantities with the temperature, the Coulombic impurity potential and the QD confinement strength are studied in detail. We find that (1) These physical quantities will increase with increasing temperature. (2) They are increasing functions of the confinement strength due to the existence of the Coulombic impurity potential between the electron and the hydrogen-like impurity. (3) We obtain three ways of tuning them via controlling the temperature, the Coulombic impurity potential and the confinement strength.

强耦合条件下内腔电磁诱导透明和正交模劈裂的研究

强耦合条件下内腔电磁诱导透明和正交模劈裂的研究

Lasing and high-temperature phase transitions in atomic systems with dressed-state polaritons

We consider the fundamental problem of high temperature phase transitions in the system of high density two-level atoms off-resonantly interacting with a pump field in the presence of optical collisions (OCs) and placed in the cavity. OCs are considered in the framework of thermalization of atomic dressed state (DS) population. For the case of a strong atom-field coupling condition we analyze the problem of thermodynamically equilibrium superradiant phase transition for the order parameter representing a real amplitude of cavity mode and taking place as a result of atomic DSs thermalization process. Such transition is also connected with condensed (coherent) properties of low branch (LB) DS-polaritons occurring in the cavity. For describing non-equilibrium phase transitions we derive Maxwell-Bloch like equations which account for cavity decay rate, collisional decay rate and spontaneous emission. Various aspects of transitions to laser field formation by using atomic DS levels for both positive and negative detuning of a pump field from atomic transition frequency are studied in detail. It is revealed, that for positive atom-light detuning DS lasing can be obtained in the presence of quasi-equilibrium DS population that corresponds to a true two-level atomic system with the inversion in nonresonant limit.