The development of 0.67Hp gasoline generator cylinder block and the material optimization of the component using Taguchi Design and Finite Element Method were carried out successfully. The cylinder block is known to create an avenue for the piston to carry out its reciprocating effect on the crankshaft for onward transmission for the machine output. The designed cylinder block had an engine power of 5.11kw which drove piston through a bore and stroke length of 46.10mm and 51.20mm respectively. The determined clearance volume of 9.46cm 3 was contained in a cylinder wall thickness and block length of 3.04mm and 58.88mm respectively. The designed values were found to be in consonance with recommended values obtained in standard engineering text. The developed mathematical model was determined to be adequate with a statistical Coefficient of determination (R 2 ) of 98.62% and the Adjusted coefficient of determination (Adj R 2 ) was found to be 97.79%. The comparison of optimal values developed from the Taguchi design and genetic algorithm optimizations showed that obtained values from both methods were noticed to be very close as only a difference of about 0.0005 existed among the input parameters. The genetic algorithm result was seen as a kind of validation for the Taguchi design optimization. The Finite element analysis result showed that the temperature output result recorded the highest temperature of 100 o C around the cylinderical bore axis while the lowest temperature of 51.97 o C was found on the cooling fins of the component. Keywords: Optimization, Taguchi Design, Genetic Algorithm and Finite Element Analysis. DOI: 10.7176/JIEA/12-1-04 Publication date: March 31 st 2022