Strict Lockdown Research Articles

Eating behaviors and physical activity during the COVID-19 pandemic lockdown: Experiences of breast cancer patients on adjuvant hormonal therapy

Background/Aim. Since the coronavirus disease 2019 (COVID-19) pandemic led to a strict lockdown in Serbia, the population has experienced drastic lifestyle changes. Physical distancing, self-isolation, limited availability of essential food products, and the stress related to the availability of therapy during the pandemic particularly affected the lives of vulnerable groups, such as breast cancer (BrC) patients. The aim of this study was to examine the changes in eating behaviors and physical activity of postmenopausal BrC patients on adjuvant hormonal therapy under the COVID-19 lockdown conditions. Methods. This observational retrospective pre-post cohort study included 32 women treated with aromatase inhibitors (AIs) who responded to telephone interviews using a structured questionnaire. The questionnaire aims to collect data on eating habits (intake of certain foods on a daily/weekly basis, as well as changes in the usual choice of food), intake of supplements, changes in weight, and physical activity before and during the lockdown. Results. The results showed that, due to problems in obtaining groceries, the patients cooked and consumed homemade sweets and fruit more often (47% of the respondents), while fewer (31%) consumed fresh fish. Nearly 41% of patients reported increased food intake, and 88% reported decreased physical activity, which led to an increase in body weight in as many as 47% of subjects. The intake of supplements was doubled. Conclusion. The COVID-19 lockdown with home confinement exacerbated health risks and affected dietary patterns and physical activity, which may have had a negative impact on the long-term health of BrC patients treated with AIs.

Knowledge, Attitude, and Practice of COVID-19 among the Exposed Frontline Police Workers in Eastern Uttar Pradesh Region: An Exploratory Study

Background: The world has been hit by an unknown obstacle in the form of the COVID-19 pandemic. India also faced a never seen before situation in trying to contain the spread of COVID-19 by enforcing one of the most stringent lockdowns in the world. The billion-plus population of the country throws a severe challenge at the operational level in enforcing the measures. The frontline workers in these trying times such as the Police, Central Industrial Security Force, health-care workers, volunteers, and essential service workers have done a praiseworthy job under exceptionally hard conditions. Aim: The study aimed to investigate the awareness of COVID-19 among the frontline police workers who were posted during lockdown in our state. Materials and Methods: A questionnaire comprising 25 questions was randomly distributed among the police personnel who were on COVID-19 duty. The knowledge they had was assembled, assessed, and scrutinized. Results: A total of 150 police officers took part in the study. Mean age of 39.91 ± 9.96 years was seen. The majority of them had enough knowledge about the ongoing pandemic and they were seen to be taking good precautions to fight the virus. Conclusion: The joint effort of public and the frontline workers was the mainstream reason to bring our country back on track. Police had put their best efforts into controlling the spread of this contagion by maintaining a strict lockdown. They did immensely well and we as citizens should be grateful to them for protecting us from this pandemic.

Impact of Supply Chain Disruptions on Economic Growth: Insights From a Major Public Health Crisis.

Supply chain disruptions caused by major public health crises will severely impact the economic growth. The main purpose of this paper is to examine the above proposition, taking the strict lockdown policy and supply chain disruption in Hubei Province at the beginning of the COVID-19 epidemic as a case, to provide decision-making reference for the government in supply chain management under major public health crisis. To achieve this goal, this paper firstly measures the supply chain network of Hubei province via the multi-region and multi-sector value-added model; then empirically studies the impact of lockdown policy and supply chain disruption on provincial economic growth, with the monthly data of 31 provinces covering January 2018 to December 2022, by the Difference in Difference method. The results show that: the lockdown policy and supply chain disruption under the Covid-19 epidemic negatively affected provincial economic growth; moreover, supply chain disruptions make provinces closer to Hubei more vulnerable to economic shocks. The results are significant in the placebo test, and are further supported in the robustness test of alternative variables and data. We further discussed the Business Cycle Co-movement between Hubei and other provinces, and the probable impact mechanism of supply chain interruption on economic growth in the Covid-19 epidemic. This study shows that supply chain network plays an important role in the transmission of interregional economic shocks, as well as its importance for economic growth, especially in major public health crises.

Evaluation of a national program to distribute free face masks in Uganda: Evidence from Mbale District.

COVID-19 posed a major threat to countries around the world, but many nations in sub-Saharan Africa avoided large-scale outbreaks. In Uganda, the government first enacted strict lockdowns but later focused on public health policies like masking and distancing. The government also embarked on an ambitious campaign to deliver a free face mask to all Ugandan citizens (approx. 30 million masks). We test whether mask distribution, and public education and encouragement of mask use by community health volunteers, affected mask behavior. We collected data about mask behavior before and after masks were distributed in the Mbale district of Uganda. Trained enumerators directly observed mask wearing in public places and asked about mask use via phone surveys. We compared observed and self-reported mask behavior before and after masks were distributed. We also tested whether training volunteers from randomly selected villages to educate the public about COVID-19 and masks affected behavior, attitudes, and knowledge among mask recipients. We collected 6,381 direct observations of mask use at baseline (February 2021) and 19,855 observations at endline (April 2021). We conducted a listing of 9,410 households eligible for phone surveys and randomly selected 399 individuals (4.2%) at baseline and 640 (6.8%) at endline. Fewer than 1% of individuals were observed wearing masks at baseline: 0.9% were seen with a mask and 0.5% wore masks over mouth and nose. Mask wearing significantly increased at endline but remained low: 1.8% of people were observed with masks and 1.1% were seen wearing masks correctly after the distribution campaign. At the same time, a high proportion of people reported using masks: 63.0% of people reported using masks at baseline and 65.3% at endline when walking around their villages. When respondents were asked about mask use in public places, 94.7% reported using masks at baseline and 97.4% reported using masks at endline. We found no differences in knowledge, behavior, or attitudes among mask recipients in villages where volunteers were tasked with conveying information about COVID-19 and masks during distribution. Mask use remained low in Mbale district of Uganda during study observation period even after free masks were distributed. Encouraging new health behaviors may need to involve more intensive interventions that include reminders and address social norms.

Access to and Utilization of Maternal and Child Healthcare Services During COVID-19 Pandemic in Rural Bangladesh.

Geographically remote areas in lower-middle-income countries like Bangladesh experienced significant Maternal and Child Health (MCH) care shortages during the COVID-19 pandemic. These shortages were exacerbated by preexisting inadequate public health infrastructure and using existing health resources for pandemic management. The objective of this study was to assess the status of access to and utilization of maternal and child healthcare services among rural people during the outbreak of COVID-19. A community-based descriptive, exploratory, cross-sectional study was carried out from May to August 2020 among the rural people of the four districts of northern Bangladesh. A total of 639 women were included in the study with a sample random sampling technique, and multistage random sampling techniques were applied to select the study area. A pretested semi-structured questionnaire was used for data collection. SPSS Version 22 was used for the statistical analysis. The mean age of the respondents was 34.3 years with an SD ± 10 years. 37.7% of respondents belonged to the 21-30 year age group followed by the 31-40 years age group (34.9 %). Of the total 639 respondents, 59.5% were female. There were significant associations and moderate positive correlations between educational qualification, occupational status, and age group of the respondents (p=0.001). Most of the respondents (67.6%) indicated that they experienced health problems during COVID-19 with 70.6% of them specifically mentioning MCH-related problems. Out of them, only 33.1% mentioned they could access and utilize MCH services, whereas 66.9% of them could not access MCH Services. Major barriers to utilizing MCH services were the COVID-19 lockdown, lack of transport facilities, fear of being infected, shutdown of healthcare facilities, and unavailability of healthcare professionals. The differences in health facility usage before and during COVID-19 are statistically significant with p = < 0.001. During the COVID-19 pandemic, access to and utilization of MCH services was significantly hampered, particularly in Bangladesh's remote and rural regions during the strict lockdown times. The identified barriers were the COVID-19 lockdown, lack of transport facilities, fear of being infected, shutdown of healthcare facilities, and unavailability of healthcare professionals. Building strengthened health systems, capacity building of informal healthcare providers, backup plans, and alternate service delivery models are necessary to ensure access to maternity and child health. For future pandemics and natural disaster situations, the 'concerned officials should strategically have backup plans and alternative service delivery models to strengthen the health system. And, there should be collaborative efforts among the countries to support each other to address the crisis situations.

The effect of the COVID-19 pandemic on the trends and characteristics of natural and unnatural deaths in an urban Sri Lankan cohort viewed through retrospective analysis of forensic death investigations from 2019 to 2022.

The coronavirus disease 2019 (COVID-19) pandemic has had a severe impact on global health. Apart from the disease itself, the strict restrictions and lockdowns enforced to minimize its spread have also substantially disrupted personal and public health. An analysis of forensic autopsy investigations was conducted between 2019 and 2022 on a selected urban population in Colombo, Sri Lanka, assessing the effects of the COVID-19 pandemic on mortality within these communities. During the COVID-19 restrictions, there was a 2.5-fold increase in the total number of deaths, with a significantly higher percentage of female deaths than before. The majority of these deaths were due to cardiovascular causes, while COVID-19-related deaths ranked third overall. The highest proportion of COVID-19 deaths occurred among unvaccinated females. The monthly frequency of deaths from traffic accidents, poisoning, and asphyxiation decreased, while deaths from blunt trauma, sharp trauma, burns, and immersion increased. There was also a rise in blunt homicides and a greater number of femicides during the COVID-19 restrictions than in the pre-pandemic period. A significantly higher percentage of males who received the COVID-19 vaccine died from cardiovascular causes compared to those in the unvaccinated group. The significant changes in mortality demographics and causes of death within this community during the COVID-19 restrictions underscore the disruption in healthcare, healthseeking behavior, and social interactions during this period. The vulnerability of individuals residing in highly urbanized areas with lower socioeconomic status, particularly women, is brought into sharp focus.

Stereotype Belief on Feminism Jurisprudence: An Analysis to Aggression in Women

Despite measures being taken around the world to protect and value women, they remain vulnerable to oppression. At the height of the global pandemic many cases of abuse against women have been recorded especially domestic violence where the perpetrator and victim are together in their home due to strict lockdown. This study was conducted to find out the perspective of the female-victims on the root cause of their oppression from the hands of the aggressors and its continuing factor. The researcher used snowball sampling and descriptive research design triangulated by secondary and primary data. Thirty-four respondents from Nueva Ecija, Philippines answered the survey and were interviewed with the assistance of authorities. The study revealed that the most common violence experienced by women are psychological violence and sexual abuse and these stem from the superiority complex of the men and sexual desire to women. Respondents also described how women should be treated and it was revealed that all victims strongly agree with the highest level of conformity that the dignity of a woman should be respected. Further, the study proved that women’s silence and tolerance of abuse against them is a result of their belief in the superiority of men over women which becomes a constant factor in women’s oppression. The result of the study indicates the lack of power and futility of the law to protect women who chose to remain silent. The law to protect women is meaningless no matter how cruel it is when the victim’s silence precedes justice. No economic violence was found in this study which may be due to the women’s financial status as not a significant factor to experience oppression. Further researcher on the similar topic and purpose with more respondents with a qualitative method to find a more accurate and detailed result is recommended.

Hip fractures in Israel during the COVID-19 pandemic

Efforts to contain the COVID-19 pandemic temporarily changed socializing behaviors as well as health care, including orthopedic trauma care. The Israeli National Program for Quality Indicators (NPQI) has been monitoring the incidence, timeliness, and outcomes of Hip Fracture (HF) surgical repair in all Israeli hospitals since 2013. The aim of this study is to examine the effect of the COVID-19 outbreak on HF incidence, treatment, and outcomes. An NPQI Quality Indicator requires surgical repair within 48 h of hospitalization. Records from 2018 through 2021 were compared. We found annual HF incidence relatively stable, with a drop in 2020. The median Length of Stay (LoS) was shorter in 2020 than in the pre-pandemic period, as was the median admission-to-surgery time. However, in 2021, the LoS and admission-to-surgery times rebounded towards pre-pandemic values. There was a noticeable decline in HF incidence during the two strict lockdown periods, followed immediately by short-term relative rises. 30-day mortality, median age, and gender distribution remained stable over the study period. In conclusion, the COVID-19 pandemic lockdown periods had a noticeable impact on HF incidence in Israel, with a decrease during lockdowns followed by a rebound effect. Additionally, the pandemic situation had an effect on the timing of surgical repairs, with shorter LoS and time to surgery. In 2021, there was a gradual return to pre-pandemic values. These findings point to a need for continued monitoring and adaptation of healthcare systems to respond to changing circumstances and ensure optimal care for patients with HF. The fact that HF incidence decreased during strict lockdowns and rebounded afterward points to a need to adapt public places to be safer for the elderly.

Social restrictions, leisure and well-being

A wide-ranging public debate surrounds how pandemic lockdown measures differentially impacted individuals and which precise mechanisms – whether financial-, health-, or policy-driven – predominate in determining these effects. Using a nationally representative 24-h diary survey covering the first two years of the pandemic, we explore potential mechanisms underlying changes in well-being. We exploit the variation in the stringency of the social restrictions implemented by the UK government during this period and use an event-study methodology to net out the impact of social restrictions from other pandemic effects. We find that well-being dropped by 47 % (for men) and 71 % (for women) of a standard deviation during the strictest lockdown and that it took longer to revert to pre-pandemic levels than previously estimated. This finding holds after we account for financial conditions and changes in local infection and death rates, suggesting that the time use–related changes driven by social restrictions dominate financial and health shocks in driving the overall well-being effects during the pandemic. Our detailed data on time allocation and individual preferences over the activities undertaken throughout the day suggest that the drop in well-being was primarily associated to a drastic reduction in time spent in leisure with non–household members or outside the home, a category with greater weight in the well-being of women.

The impact of COVID-19-related restrictions on pregnancy and abortion rates in the Republic of Georgia

BackgroundThe Republic of Georgia implemented COVID-19-related restrictions starting on 31 March 2020, when it imposed a 1-month strict lockdown, after which the country continued with some form of restrictions for 1 year. These restrictions created barriers to healthcare access, affected healthcare services, caused severe economic degradation, and changed reproductive behavior. The aim of this study was to explore the impact of COVID-19-related restrictions on pregnancy and abortion rates in Georgia.MethodsInformation on pregnancy, abortion, and related variables was extracted from the Georgian Birth Registry from January 2018 through April 2022. The final study sample included 232,594 pregnancies and 86,729 abortions. We used interrupted time series analysis to study the impact of COVID-19-related restrictions.ResultsThere were slightly decreasing trends in pregnancy and abortion rates in the pre-pandemic period (1 January 2018-31 March 2020). During the 1-month strict lockdown (1 April-30 April 2020), pregnancy and abortion rates decreased in all investigated age groups. There were no substantial differences in pregnancy or abortion rates in the pandemic period (for pregnancies: 1 April 2020-30 June 2021; for abortions: 1 April 2020-30 April 2022) compared to the pre-pandemic period. The precision of all estimates suggested that both small increases and decreases in pregnancy and abortion rates are reasonably compatible with our data.ConclusionsDespite the 1-year-long COVID-19-related restrictions, our results did not indicate substantial long-term changes in pregnancy or abortion rates during the study period for any age group. This may indicate that the restrictions did not substantially influence access to contraception, abortion services, or reproductive behavior.

Insights from the 2-year-long human confinement experiment in Grand Cayman reveal the resilience of coral reef fish communities

In March 2020, the world went into lockdown to curb the spread of the novel coronavirus (SARS-CoV-2), with immediate impacts on wildlife across ecosystems. The strict 2-year long lockdown in Grand Cayman provided an unprecedented opportunity to assess how the ‘human confinement experiment’ influenced the community composition of reef fish. Using a suite of multivariate statistics, our findings revealed a stark increase in reef fish biomass during the 2 years of lockdown, especially among herbivores, including parrotfish, with drastic increases in juvenile parrotfishes identified. Additionally, when comparing baseline data of the community from 2018 to the 2 years during lockdown, over a three-fold significant increase in mean reef fish biomass was observed, with a clear shift in community composition. Our findings provide unique insights into the resilience of reef fish communities when local anthropogenic stressors are removed for an unprecedented length of time. Given the functional role of herbivores including parrotfish, our results suggest that reductions in human water-based activities have positive implications for coral reef ecosystems and should be considered in future management strategies.

COVID-19 and mental health in China: the effects of personality

BackgroundChina was the first country affected by the COVID-19 virus, and it is a very important case to study the effects of the virus and the consequent restrictions. However, national...

A Comparative Multicenter Cohort Study Evaluating the Long-Term Influence of the Strict Lockdown during the First COVID-19 Wave on Lung Cancer Patients (ARTEMISIA Trial).

The consequences of the strict health restrictions during the first wave of COVID-19 on lung cancer (LC) patients are not known. This cohort study evaluated the impact of the initial lockdown on management of and long-term outcome in LC patients. This exposed-unexposed-type study included two evaluation periods of 6 months each in non-selected patients; one began on the first day of lockdown in 2020, and the other in 2019 during the same calendar period. Various indicators were compared: clinical profiles, management delays and overall survival beyond 2 years. A total of 816 patients from 7 public or private centers were enrolled. The clinical characteristics of the patients in 2020 did not differ from those in 2019, except that the population was older (p = 0.002) with more non-smokers (p = 0.006). Delays for pre-therapeutic medical management were generally reduced after the first imaging in 2020 (1.28 [1.1-1.49]). In the multivariate analysis, being part of the 2020 cohort was correlated with better prognosis (HR = 0.71 [0.5-0.84], p < 0.001). The gain observed in 2020 mainly benefited non-smoking patients, along with ECOG PS 0-2 (p = 0.01), stage 4 (p = 0.003), squamous cell carcinoma (p = 0.03) and receiving systemic therapy (p = 0.03). In conclusion, the first lockdown did not exert any deleterious impact on LC patients.

Use of health services and medication use, new comorbidities, and mortality in patients with chronic diseases who did not contract COVID-19 during the first year of the pandemic: a retrospective study and comparison by sex

BackgroundThe restrictions introduced to stop the spread of the COVID-19 virus have also had a direct impact on people with chronic diseases and especially on diseases to which lifestyles are relevant in their control and management, such as diabetes, hypertension, chronic obstructive pulmonary disease (COPD), etc. The purpose of this paper is to conduct a longitudinal analysis of new comorbidities, mortality, medication use, and the use of health resources in patients with chronic diseases who did not contract COVID-19, comparing the six months before the strict lockdown to the 12 months following the end of the strict lockdown.MethodAn observational real world data pre-post study of 668,974 people was undertaken. The patients studied were over 16 years of age, had been receiving care from the Aragon Health Service (Northeastern Spain), were diagnosed with one or more chronic diseases, and had not contracted COVID-19. Sociodemographic, comorbidity, pharmacological and health resource use variables were collected during the six months before the onset of the lockdown and during the six and 12 months following the end of the lockdown. The comparisons by sex were carried out using a Student T-test or chi-squared test to analyse differences.ResultsDyslipidaemia (42.1%) followed by hypertension (35.1%) and anxiety and depression (34.6%) were the most prevalent chronic diseases among the study population. 78.% of patients had between one and four chronic illnesses. There was a decrease in new diagnoses of other chronic comorbidities in this population and a decrease in medications prescribed and the use of health services. Although women received more diagnoses of chronic diseases, the number of medications dispensed was lower, but the use of health services was higher. These figures were maintained throughout the pandemic.ConclusionOur results suggest an underdiagnosis of new chronic comorbidities and a decrease in mortality rates from causes unrelated to COVID-19 due to the closure of health centres in Aragón (Spain) during the lockdown. This trend was exacerbated in women. The underdiagnosis of new chronic comorbidities during confinement can cause the disease to worsen, with the consequent increase in symptoms and the worsening of chronic pathologies in patients with a severe evolution.

Impacts of irregular and strategic lockdown on air quality over Indo-Pak Subcontinent: Pre-to-post COVID-19 analysis

The COVID-19 pandemic has received enormous attention worldwide due to its environmental, and societal impacts. After the discovery of this novel virus in December 2019, the governmental bodies have suspended the social and economic activities and declare an unprecedented lockdown emergency. The present work sought to investigate the impact of COVID-19 containment measures on air quality in the region of Indo-Pak subcontinent (IPS). The satellite retrievals of aerosol optical depth (AOD), sulfur dioxide (SO2), nitrogen dioxide (NO2), and Ozone (O3) was used to estimate the spatial-temporal extent of major air pollutants in the region during lock down period (March–May 2020) in comparison to the pre-lockdown period (March–May 2015–2019) and post-lockdown (March–May 2021) across the IPS. From the results, a considerable reduction in air pollutants concentration has been observed during the lockdown phase that in turns significantly improved the regional air quality. Moreover, we have also done comparative analysis among meteorological parameters and ambient air pollutants and observed that meteorological factors were not the main reason for the dramatic reductions of pollutants in the atmosphere. In addition, backward trajectory analysis has been done through the Hybrid Single Particle Lagrangian Integrated Trajectory (HYSPLIT) model to find the path and direction of air particles parcels as large-scale atmospheric circulation is a critical factor in driving pollutant. Following the implementation of strict lockdown, reduction in anthropogenic activities led to a substantial decline in AOD, SO2 and NO2 whereas, a considerable increase in tropospheric O3 has been observed and well supported by other regional studies. Overall, the findings of this study are believed to be a useful addition to the regulatory authorities and will help the policymakers to formulate the air pollution mitigation strategies in a long-term perspective.

Food sharing in a pandemic: Urban infrastructures, prefigurative practices and lessons for the future

The outbreak of COVID-19 raised critical questions about the functionalities of urban infrastructures, and in particular, practices of food provision, consumption and distribution. This paper focuses on the actions of non-commercial collaborative food sharing practices in Dublin city, incorporating surplus food redistribution initiatives, community kitchens, and community gardens, during the first wave of the pandemic in 2020. Whilst initially curtailed under conditions of strict lockdowns, many of these food sharing initiatives became characterised as essential services as the crisis unfolded, offering infrastructures of mobility, accessibility and care. Focusing on urban food infrastructures, qualitative content analysis of online media debates around food sharing in Dublin during this period was conducted to explore how non-commercial food sharing initiatives have been affected by, and responded to, the COVID-19 outbreak in Dublin. The paper analyses forms of improvisation, institionalisation and impact that emerged through food sharing actions and reflects on whether food sharing initiatives prefigure more sustainable urban food systems.

The impact of COVID-19 pandemic on pet behavior and human-animal interaction: a longitudinal survey-based study in the United States

IntroductionAlthough multiple studies have explored behavioral changes in pets during the strict lockdown of the COVID-19 pandemic between May and July 2020, this longitudinal study uniquely investigated the phases beyond strict lockdown. The primary objective of this research was to evaluate the pandemic’s impact on pet behavior.MethodsTo achieve this goal, we conducted an online survey, completed by pet owners residing in the United States between June 2020 (including retrospective data for February and April 2020) and December 2021. The study encompassed four distinct pandemic phases: Pre-pandemic (data collected retrospectively), Strict lockdown, Prolonged lockdown, and Re-opening.Results and discussionThe data collected from surveys completed by 3,278 pet owners across one to six time points revealed declining trends in all investigated behavior problems of both dogs and cats. Concurrently, human-animal interaction activities also showed variations across different COVID-19 phases. The association between human-animal interactions and the occurrence of behavior problems underscored the importance of not only exercise quantity but also adherence to consistent schedules, particularly for dogs, in mitigating behavior problems. Interestingly, among cats, sleeping outside the bedroom was associated with a reduced occurrence of aggression, anxiety, fear, and physiological behavior changes. However, sleep location displayed limited or no association with behavior problems in dogs. In summary, this study highlights the importance of tailoring interventions to the unique needs of each species through human-animal interactions to mitigate the occurrence of behavioral problems and enhance human-animal relationships.

Protective factors for children with autism spectrum disorder during COVID-19-related strict lockdowns: a Shanghai autism early developmental cohort study.

COVID-19 lockdowns increased the risk of mental health problems, especially for children with autism spectrum disorder (ASD). However, despite its importance, little is known about the protective factors for ASD children during the lockdowns. Based on the Shanghai Autism Early Developmental Cohort, 188 ASD children with two visits before and after the strict Omicron lockdown were included; 85 children were lockdown-free, while 52 and 51 children were under the longer and the shorter durations of strict lockdown, respectively. We tested the association of the lockdown group with the clinical improvement and also the modulation effects of parent/family-related factors on this association by linear regression/mixed-effect models. Within the social brain structures, we examined the voxel-wise interaction between the grey matter volume and the identified modulation effects. Compared with the lockdown-free group, the ASD children experienced the longer duration of strict lockdown had less clinical improvement (β = 0.49, 95% confidence interval (CI) [0.19-0.79], p = 0.001) and this difference was greatest for social cognition (2.62 [0.94-4.30], p = 0.002). We found that this association was modulated by parental agreeableness in a protective way (-0.11 [-0.17 to -0.05], p = 0.002). This protective effect was enhanced in the ASD children with larger grey matter volumes in the brain's mentalizing network, including the temporal pole, the medial superior frontal gyrus, and the superior temporal gyrus. This longitudinal neuroimaging cohort study identified that the parental agreeableness interacting with the ASD children's social brain development reduced the negative impact on clinical symptoms during the strict lockdown.

Trends in the COVID-19 Pandemic in Italy during the Summers of 2020 (before Mass Vaccination), 2021 (after Primary Mass Vaccination) and 2022 (after Booster Mass Vaccination): A Real-World Nationwide Study Based on a Population of 58.85 Million People.

During the state of national health emergency and the Draghi government, the Civil Defense Department released the aggregate data coming from the Ministry of Health, the Higher Institute of Health, the Independent Provinces and the Italian Regions daily, in order to inform about the pandemic situation in Italy. Among these data there were the number of deaths, hospitalizations in intensive care units (ICU), non-ICU patients, contagions and performed swabs. By means of a team effort, we have collected and elaborated all these data, comparing the COVID-19 pandemic in Italy during the summers of 2020 (following the nationwide lockdown), 2021 and 2022. from the summer of 2020 to the summers of 2021 and 2022 all pandemic trend indicators have shown a sharp worsening in Italy. COVID-19 deaths increased by ≈298% and ≈834%, ICU hospitalizations by ≈386% and ≈310%, non-ICU hospitalizations by ≈224% and ≈600%, contagions by ≈627% and ≈6850% (i.e., ≈68.50 times), swabs by ≈354% and ≈370%, and the mean positivity rate passed from ≈1% to ≈2% and ≈20%, respectively. SARS-CoV-2 can be transmitted in any climate, including areas with hot and humid weather, and the emergence of variants adapted to hot-humid climates may result in summer COVID-19 outbreaks, even in neither tropical nor subtropical countries. Although COVID-19 vaccines can confer cross-protection against newly emerging variants, this cross-immunity is naturally not absolute but limited, considering that vaccine protection wanes significantly after 6 months. It follows that a subject vaccinated at the beginning of the winter will not be completely covered in the height of the summer, and we should not forget the unvaccinated. As a final remark, the long and strict nationwide lockdown made it possible to flatten SARS-CoV-2 circulation and, therefore, its negative impact on Italy during the summer of 2020.

Analyzing urban parks’ spatial integration in Budapest to understand changes in visitation patterns during the COVID-19 pandemic

Globally, dramatic changes in park visitation have accompanied the COVID-19 pandemic. In general, cities have experienced an overall increase in park visitation after strict lockdowns imposed in the pandemic’s first wave have been removed. However, previous research conducted in Hungary has demonstrated that park visitation varied across parks with different sizes and locations in the city. We hypothesized that the degree of the park’s integration into the urban fabric significantly affected changes in visitation. To test this hypothesis, we conducted a space syntax analysis. Findings show that community parks with an area of 10.01–50.00 hectares and a mean spatial integration of 83.37 experienced the highest increase in the number of visitors (based on mobile devices’ GNSS data). Surprisingly, large metropolitan parks providing highly complex ecosystem services lost many visitors during the pandemic, which might be due to their low spatial integration.