Stresses In Cancellous Bone Research Articles

A Finite Element Analysis of Peri-implant Stresses Surrounding Zirconium and Titanium Dental Implants

ABSTRACT Introduction: Stresses tend to vary depending on the kind of implant material (titanium or zirconium) because of differences in their mechanical and physical characteristics. Objectives: The current research was done to assess the peri-implant stresses around zirconium and titanium dental implants using finite element analysis. Materials and Method: Three distinct implant configurations were used to create three-dimensional finite element models (M1, M2, and M3) using ANSYS (11.0 Version) software, a P4 CPU running at 3 GHz, and hardware with three gigabytes of RAM. These configurations are typical for zirconium and titanium implants. Under 250 N of axial force and 50 N of nonaxial load, the stress surrounding the implants was examined. Result: When compared to titanium implants, zirconium implants displayed higher strains in cancellous bone and lower stresses in cortical bone. Overall, titanium implants caused larger stresses in the bone than zirconium implants. Conclusion: Compared to titanium implants, zirconium implants resulted in reduced peri-implant stresses.

Optimizing functionally graded tibial components for total knee replacements: a finite element analysis and multi-objective optimization study

The optimal design of complex engineering systems requires tracing precise mathematical modeling of the system’s behavior as a function of a set of design variables to achieve the desired design. Despite the success of current tibial components of knee implants, the limited lifespan remains the main concern of these complex systems. The mismatch between the properties of engineered biomaterials and those of biological materials leads to inadequate bonding with bone and the stress-shielding effect. Exploiting a functionally graded material for the stem of the tibial component of knee implants is attractive because the properties can be designed to vary in a certain pattern, meeting the desired requirements at different regions of the knee joint system. Therefore, in this study, a Ti6Al4V/Hydroxyapatite functionally graded stem with a laminated structure underwent simulation-based multi-objective design optimization for a tibial component of the knee implant. Employing finite element analysis and response surface methodology, three material design variables (stem’s central diameter, gradient factor, and number of layers) were optimized for seven objective functions related to stress-shielding and micro-motion (including Maximum stress on the cancellous bone, maximum and mean stresses on predefined paths, the standard deviation of mean stress on paths, maximum and mean micro-motions at the bone-implant interface and the standard deviation of mean micro-motion). Then, the optimized functionally graded stem with 6 layers, a central diameter of 5.59 mm, and a gradient factor of 1.31, was compared with a Ti6Al4V stem for various responses. In stress analysis, the optimal stem demonstrated a 1.92% improvement in cancellous bone stress while it had no considerable influence on the maximum, mean, and standard deviation of stresses on paths. In micro-motion analysis, the maximum, mean, and standard deviation of mean micro-motion at the interface were enhanced by 24.31%, 39.53%, and 19.77%, respectively.

Study on mechanical properties of dual-channel cryogenic 3D printing scaffold for mandibular defect repair.

Mandibular defect repair has always been a clinical challenge, facing technical bottleneck. The new materials directly affect technological breakthroughs in mandibular defect repair field. Our aim is to fabricate a scaffold of advanced biomaterials for repairing of small mandibular defect. Therefore, a novel dual-channel scaffold consisting of silk fibroin/collagen type-I/hydroxyapatite (SCH) and polycaprolactone/hydroxyapatite (PCL/HA) was fabricated by cryogenic 3D printing technology with double nozzles. The mechanical properties and behaviors of the dual-channel scaffold were investigated by performing uniaxial compression, creep, stress relaxation, and ratcheting experiments respectively. The experiments indicated that the dual-channel scaffold was typical non-linear viscoelastic consistent with cancellous tissue; the Young's modulus of this scaffold was 60.1kPa. Finite element analysis (FEA) was employed performing a numerical simulation to evaluate the implantation effect in mandible. The stress distribution of the contact area between scaffold and defect was uniform, the maximum Mises stress of cortical bone and cancellous bone in defect area were 54.520MPa and 3.196MPa, and the maximum displacement of cortical bone and cancellous bone in defect area were 0.1575mm and 0.1555mm respectively, which distributed in the incisor region. The peak maximum Mises stress experienced by the implanted scaffold was 3.128 × 10-3MPa, and the maximum displacement was 6.453 × 10-2mm distributed near incisor area. The displacement distribution of the scaffold was consistent with that of cortical and cancellous bone. The scaffold recovered well when the force applied on it disappeared. Above all, the dual-channel scaffold had excellent bio-mechanical properties in implanting mandible, which provides a new idea for the reconstruction of irregular bone defects in the mandible and has good clinical development prospects.

Stress distribution pattern in all-on-four maxillary restorations supported by porous tantalum and solid titanium implants using three-dimensional finite element analysis.

Success/failure of dental implants depends on stress transfer and distribution at the bone-implant interface. This study aimed to assess the stress distribution pattern in all-on-four maxillary restorations supported by porous tantalum and solid titanium implants using three-dimensional (3D) finite element analysis (FEA). In this FEA, a geometric model of an edentulous maxilla, Zimmer screw-vent tantalum and solid titanium implants were modelled. Four models with the all-on-four concept were designed. The fifth model had 6 vertical implants (all-on-six). Two different implant types (porous tantalum and solid titanium) were modelled to yield a total of 10 models, and subjected to 200 N bilateral vertical load. Pattern of stress distribution and maximum von Mises stress values in cancellous and cortical bones around implants were analysed. In tantalum models, the effect of increasing the distal tilting of posterior implants was comparable to the effect of increasing the number of implants to 6 on von Mises stress values in cortical bone. However, in cancellous bone, the effect of increasing the tilting of posterior implants on stress was slightly greater than the effect of increasing the number of implants to 6. In solid titanium models, the effect of both of the abovementioned parameters was comparable on stress in cancellous bone; but in cortical bone, the effect of increasing the implant number was slightly greater on stress reduction. Despite similar pattern of stress distribution in bone around implants, higher maximum von Mises stress values around tantalum implants indicate higher stress transfer capacity of this type of implant to the adjacent bone, compared with solid titanium implants.

Investigating the Influence of All-Ceramic Prosthetic Materials on Implants and Their Effect on the Surrounding Bone: A Finite Element Analysis

This study aims to assess and compare the impact of Monolithic Zirconia (MZ) and In-Ceram Zirconia (ZP) superstructures on stress distribution within implants and D2/D4 bone densities under 200 N vertical and oblique occlusal loads using three-dimensional finite element analysis via ANSYS WORKBENCH R2. The analysis employed maximum and minimum von Mises stress values. Modeling an implant (4.2 mm diameter, 10 mm length) and abutment (0.47 mm diameter), with an 8 mm diameter and 6 mm length single crown, the research identified lower von Mises stresses in D2 cancellous bone with the MZ model under vertical loading. Conversely, under oblique loading, the ZP model exhibited maximum von Mises stresses in D4 bone around the implant. This underscores the critical need to consider physical and mechanical properties, beyond mere aesthetics, for sustained implant success. The findings highlight the effect of material composition and stress distribution, emphasizing the necessity of durable and effective implant treatments.

Biomechanical properties of lumbar vertebral ring apophysis cage under endplate injury: a finite element analysis

ObjectiveThis study aimed to compare the biomechanical properties of lumbar interbody fusion involving two types of cages. The study evaluated the effectiveness of the cage spanning the ring apophysis, regardless of the endplate's integrity.MethodsA finite element model of the normal spine was established and validated in this study. The validated model was then utilized to simulate Lateral Lumbar Interbody Fusion (LLIF) with posterior pedicle screw fixation without posterior osteotomy. Two models of interbody fusion cage were placed at the L4/5 level, and the destruction of the bony endplate caused by curetting the cartilaginous endplate during surgery was simulated. Four models were established, including Model 1 with an intact endplate and long cage spanning the ring apophysis, Model 2 with endplate decortication and long cage spanning the ring apophysis, Model 3 with an intact endplate and short cage, and Model 4 with endplate decortication and short cage. Analyzed were the ROM of the fixed and adjacent segments, screw rod system stress, interface stress between cage and L5 endplate, trabecular bone stress on the upper surface of L5, and intervertebral disc pressure (IDP) of adjacent segments.ResultsThere were no significant differences in ROM and IDP between adjacent segments in each postoperative model. In the short cage model, the range of motion (ROM), contact pressure between the cage and endplate, stress in L5 cancellous bone, and stress in the screw-rod system all exhibited an increase ranging from 0.4% to 79.9%, 252.9% to 526.9%, 27.3% to 133.3%, and 11.4% to 107%, respectively. This trend was further amplified when the endplate was damaged, resulting in a maximum increase of 88.6%, 676.1%, 516.6%, and 109.3%, respectively. Regardless of the integrity of the endplate, the long cage provided greater support strength compared to the short cage.ConclusionsCaution should be exercised during endplate preparation and cage placement to maintain the endplate's integrity. Based on preoperative X-ray evaluation, the selection of a cage that exceeds the width of the pedicle by at least 5 mm (ensuring complete coverage of the vertebral ring) has demonstrated remarkable biomechanical performance in lateral lumbar interbody fusion procedures. By opting for such a cage, we expect a reduced occurrence of complications, including cage subsidence, internal fixation system failure, and rod fracture.

Improving dental implant stability by optimizing thread design: Simultaneous application of finite element method and data mining approach

Lack of knowledge regarding the optimal design of thread configuration in dental implants, which can offer a satisfactory level of stability in the implant-bone construct, is a significant challenge in the field of dental biomechanics. The purpose of this finite element analysis study was to identify the optimal thread design by investigating the effects of thread parameters such as thread depth (TD), thread width (TW), and thread pitch (TP), as well as upper (α) and lower (β) thread angles, on the maximum principal stress in cancellous and cortical bone, maximum von Mises stress in the dental implant, and maximum shear stress at the implant-bone interface. A finite element model of an alveolar bone segment with a dental implant was developed. The Latin hypercube sampling method was used to generate a dataset of virtual experiments, which were analyzed by using the decision tree method to identify suitable thread designs that minimize mechanical stimuli. Additionally, the effectiveness of thread parameters on stress levels in the bone, implant, and their interface were assessed. The results of this study, verified by comparison with previous literature, indicated that TD, TW, and upper thread angle were the most effective parameters in promoting implant stability. By analyzing the decision trees, optimum ranges for all the thread parameters were determined as follows: 0.25<TD<0.34, 0.25≤TW≤0.28, 0.8≤TP≤0.88, 66.2≤α≤80, and β≤65.4, which led to the V-shape thread design.

TOPOLOGY OPTIMIZATION DESIGN AND MECHANICAL ANALYSIS OF A PERSONALIZED LUMBAR FUSION DEVICE

Objective: To reduce the shielding effect caused by the large elastic modulus of metal fusion devices after osteotomy for the treatment of scoliosis. Methods: A personalized fusion device was designed using reverse engineering techniques, three-dimensional modeling, topology optimization, and finite element analysis. A finite element model of the lumbar spine after orthopedic surgery was established from an actual case. A fusion device was implanted into the lumbar spine before and after the optimized design for simulation calculations, respectively. The similarities and differences in the mechanical properties of the different fusion devices and vertebrae were compared. Based on the topological optimization of the mechanical properties of the fusion system, a lightweight fusion device was designed and the stress-shielding effect on the lumbar vertebrae was improved. Results: The topologically optimized fusion device described in the current case was 60% lighter while maintaining the strength of the fusion. After optimization, the average strain of the fusion was increased by up to 200% and the stiffness was significantly decreased. The average equivalent stress of cancellous bone was increased by up to 9.55% for the PEEK fusion device. In contrast, the topologically optimized fusion can increase the average equivalent stress of cortical bone by 5.63% and reduce the stress-masking effect of vertebrae. Conclusion: Topologically optimized titanium alloy fusion devices can significantly reduce the mass of the implant as well as reduce fusion stiffness. Additionally, a topology-optimized titanium alloy fusion device can effectively improve the stress-shielding effect of cortical bone.

Is All-on-four effective in case of partial mandibular resection? A 3D finite element study

IntroductionThe aim of the work is to analyze stress distribution on 3D Finite Element (FE) models at bone, implant, and framework level of different designs for fixed implant-supported prostheses in completely edentulous patients, comparing results on whole and partially resected mandibles. Materials and methods3D anisotropic FE models of a whole and of a partially resected mandible were created using a TC scan of a cadaver's totally edentulous mandible. Two types of totally implant-supported rehabilitation were simulated, with four implants: parallel fixtures on whole mandible and on resected mandible, All-on-four-configured fixtures on whole mandible and on partially resected mandible. A superstructure comprising only metal components of a prosthetic framework were added, while stress distribution and its maximum values were analyzed at bone, implant, and superstructure level. ResultsThe results highlight that:(1) implant stresses are greater on the whole mandible than on the resected one;(2) framework and cancellous-bone stresses are comparable in all cases;(3) on the resected mandible, maximum stress levels at the cortical-bone/implant interface are higher than in whole-mandible rehabilitation. The opposite applies for maximum stresses on external cortical bone, measured radially with respect to the implant from the point of maximum stress at the interface. DiscussionOn the resected mandible, All-on-four configuration proved biomechanically superior to parallel implants considering radial stresses on implants and cortical bone. Still, maximum stresses increase at the bone/implant interface. A design with four parallel implants minimizes the stress on a resected mandible while, on the whole mandible, the All-on-four rehabilitation proves superior at all levels (bone, implant, and framework).

BIOMECHANICAL EVALUATION OF THE EFFECT OF VARYING MEGAPROSTHESIS LENGTHS IN PROXIMAL HUMERAL REPLACEMENT DURING AXIAL LOADING USING FINITE ELEMENT ANALYSIS

To analyse bone stresses in humerus-megaprosthesis construct in response to axial loading under varying implant lengths in proximal humeral replacement following tumour excision.CT scans of 10 cadaveric humeri were processed in 3D Slicer to obtain three-dimensional (3D) models of the cortical and cancellous bone. Megaprostheses of varying body lengths (L) were modelled in FreeCAD to obtain the 3D geometry. Four FE models: group A consisting of intact bone; groups B (L=40mm), C (L=100mm) and D (L=120mm) comprising of humerus-megaprosthesis constructs were created. Isotropic linear elastic behaviour was assigned for all materials. A tensile load of 200N was applied to the elbow joint surface with the glenohumeral joint fixed with fully bonded contact interfaces. Static analysis was performed in Abaqus. The bone was divided at every 5% bone length beginning distally. Statistical analysis was performed on maximum von Mises stresses in cortical and cancellous bone across each slice using one-way ANOVA (0-45% bone length) and paired t-tests (45-70% bone length). To quantify extent of stress shielding, average percentage change in stress from intact bone was also computed.Maximum stress was seen to occur distally and anteriorly above the coronoid fossa. Results indicated statistically significant differences between intact state and shorter megaprostheses relative to longer megaprostheses and proximally between intact and implanted bones. Varying levels of stress shielding were recorded across multiple slices for all megaprosthesis lengths. The degree of stress shielding increased with implant lengthening being 2-4 times in C and D compared to B.Axial loading of the humerus can occur with direct loading on outstretched upper limbs or indirectly through the elbow. Resultant stress shielding effect predicted in longer megaprosthesis models may become clinically relevant in repetitive axial loading during activities of daily living. It is recommended to use shorter megaprosthesis to prevent failure.

Finite element analysis of PMMA bone cement reinforced screw plate fixation for osteoporotic proximal humeral fracture

With the help of finite element analysis, to explore the effect of proximal humeral bone cement enhanced screw plate fixation on the stability of internal fixation of osteoporotic proximal humeral fracture. The digital model of unstable proximal humeral fracture with metaphyseal bone defect was made, and the finite element models of proximal humeral fracture bone cement enhanced screw plate fixation and common screw plate fixation were established respectively. The stress of cancellous bone around the screw, the overall stiffness, the maximum stress of the plate and the maximum stress of the screw were analyzed. The maximum stresses of cancellous bone around 6 screws at the head of proximal humeral with bone cement enhanced screw plate fixation were 1.07 MPa for No.1 nail, 0.43 MPa for No.2 nail, 1.16 MPa for No.3 nail, 0.34 MPa for No.4 nail, 1.99 MPa for No.5 nail and 1.57 MPa for No.6 nail. These with common screw plate fixation were:2.68 MPa for No.1 nail, 0.67 MPa for No.2 nail, 4.37 MPa for No.3 nail, 0.75 MPa for No.4 nail, 3.30 MPa for No.5 nail and 2.47 MPa for No.6 nail. Overall stiffness of the two models is 448 N/mm for bone cement structure and 434 N/mm for common structure. The maximum stress of plate appears in the joint hole:701MPa for bone cement structure and 42 0MPa for common structure. The maximum stress of screws appeared at the tail end of No.4 nail:284 MPa for bone cement structure and 240.8 MPa for common structure. Through finite element analysis, it is proved that the proximal humerus bone cement enhanced screw plate fixation of osteoporotic proximal humeral fracture can effectively reduce the stress of cancellous bone around the screw and enhance the initial stability after fracture operation, thus preventing from penetrating out and humeral head collapsing.

Reversed windshield-wiper effect leads to failure of cement-augmented pedicle screw: Biomechanical mechanism analysis by finite element experiment

The failure mode of cement-augmented pedicle screw (CAPS) was different from common pedicle screw. No biomechanical study of this failure mode named as “reversed windshield-wiper effect” was reported. To investigate the mechanisms underlying this failure mode, a series of finite element models of CAPS and PS were modified on L4 osseous model. Nine models were created according to the cement volume at 0.5 mL interval (range: 1–5 mL). Pullout load and cranio-caudal loads were applied on the screws. Stress and instantaneous rotation center (IRC) of the vertebra were observed. Under cranio-caudal load, the stress concentrated on the screw tip and pedicle region. The maximal stress (MS) at the screw tip region was +2.143 MPa higher than pedicle region. With cement volume increasing, the maximal stress (MS) at the screw tip region decreased dramatically, while MS at pedicle region was not obviously affected. As dose increased to 1.5 mL, the MS at pedicle region became higher than screw tip region and the maximal stress difference was observed at 3.5 mL. IRC of the vertebra located at the facet joint region in PS model. While IRC in CAPS models shifted anteriorly closer to the vertebral body with the increasing of cement volume. Under axial pull-out load, the maximal stress (MS) of cancellous bone in CAPS models was 29.53–50.04% lower than that 2.228 MPa in PS model. MS in the screw-bone interface did not change significantly with cement volume increasing. Therefore, the possible mechanism is that anterior shift of IRC and the negative difference value of MS between screw tip and pedicle region due to cement augmentation, leading to the screw rotate around the cement-screw complex as the fulcrum point.

Optimizing fixation methods for stable and unstable intertrochanteric hip fractures treated with sliding hip screw or cephalomedullary nailing: A comparative biomechanical and finite element analysis study

BackgroundDespite recent advances in implants and surgical techniques, catastrophic and clinical failures in the treatment of intertrochanteric fractures continue to occur, with dire consequences in an overall frail population subset. The aim of the current study is to evaluate the effect of the factors under the surgeons’ control, namely fracture reduction and implant selection, on the biomechanical behavior of fracture fixation constructs. Material-MethodsAn experimental protocol was conducted with the use of instrumented sawbones, in order to validate the finite element models. The implants used were the Gamma3®and DHS systems. Subsequently, a series of scenaria were considered, including various reduction and implant angle combinations. Data were retrieved concerning the peak cancellous bone stresses around the hip screw and the volume of cancellous bone in the femoral head stressed at critical levels, as well as implant stresses and stresses on the cortical bone of the distal fragment. ResultsAll stable fracture models displayed significantly decreased cancellous bone stresses and implant stresses compared to their unstable counterparts, regardless of implant used. The effect of increasing implant angle led to a decrease in implant stresses in all models studied, but had a beneficial effect on the stresses in the cancellous bone of the proximal fragment only in the subgroups of stable fractures with both implants and unstable fractures treated with a cephalomedullary nail (CMN). In unstable fractures anatomically reduced, the use of CMN led to significantly lower peak stresses in the cancellous bone and a smaller volume of bone stressed at critical levels. Increasing the reduction angle by 5 ° led to a significant decrease in both peak stresses and volume of bone stressed at critical levels, more prominent in the sliding hip screw (SHS) models. Decreasing the reduction angle into varus by 5 or 10 ° led to a significant increase in bone and implant stresses regardless of implant used. ConclusionsIn stable two-part (AO31.A2) fractures the use of the SHS appears to be biomechanically equivalent to CMN. In unstable, anatomically reduced fractures, the use of CMN leads to significantly reduced cancellous bone stresses and decreased rotation of the proximal fragment during loading.A reduction in varus should be avoided at all costs. In unstable fractures treated with SHS a reduction in slight valgus appears to be biomechanically beneficial. The highest implant angle that allows for proper screw position and trajectory in the femoral head should be used for stable fractures with both implants and unstable fractures treated with Gamma3®.

Evaluation of internal fixation techniques for extracapsular fracture: A finite element analysis and comparison

Background and objectivesThis study explored the optimal plates and screws fixation for extracapsular fracture by finite element analysis, and provided a biomechanical basis for clinical treatment. MethodsFour extracapsular fixation models were built and evaluated: A. One single straight four-hole plate with two bi-cortical screws on both sides and two mono-cortical screws in the middle; B. One single straight four-hole plate with four bi-cortical screws; C. Two straight four-hole plates, each with two bi-cortical screws on both sides and two mono-cortical screws in the middle; D. One L-shape four-hole plate in the back and one straight four-hole plate in the front, each with two bi-cortical screws on both sides and two mono-cortical screws in the middle. Displacements of fractured bone blocks and stress of plates, screws, cortical and cancellous bone and the deformation of plates were analyzed by finite element analysis to investigate their stability in clinical using. ResultsGroups A and B showed larger displacements of the fractured bone block, greater deformation of plates and higher risk of the plate breakage during masticatory motion. Groups C and D exhibited the minimum displacements of the fractured bone block, the stress distribution within the safe range and less deformation of the plates. In addition, double plates fixation and bi-cortical screws exceeded single plate fixation and mono-cortical screws in stability, respectively, while an L-shape plate exhibited no significant differences in the stress dispersion and the displacement reduction. ConclusionsDouble plates fixation of the extracapsular condylar fracture was a safe and stable way and bi-cortical screws should be selected as far as possible.

Biomechanical performance of the cemented acetabular cup with combined effects of bone quality, implant material combinations and bodyweight.

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Biomechanical influence of thread form on stress distribution over short implants (≤6mm) using finite element analysis.

The macro and micro design is essential to the biomechanical performance of a short implant. In this study, the implant thread parameters of short implants used in edentulous maxillae will be discussed. The aim of the study is to analyse biomechanical distinctions in different thread parameters over short implants by applying the vertical or oblique load of 130N on dental prosthesis. A 6*5mm implant will be used in posterior maxillae arch, where the molar region locates. The CAD model has been assembled by three parts, a crown, an implant system and a jaw. By applying the vertical or oblique load to the crown, the Von-Mises stresses of cortical bone and trabecular bone will be evaluated in pairs along the lines v1-v2 & a1-a2. The results showed that the reverse buttress thread would induce more stresses in cancellous bone whereas the buttress did the opposite. The trapezoidal thread (V-thread) is more favourable than thereverse buttress thread in accordance to the FEA result. The rectangle threads will induce more uneven stresses in cancellous bones.

The Effect of Implant Length and Diameter on Stress Distribution of Tooth-Implant and Implant Supported Fixed Prostheses: An In Vitro Finite Element Analysis Study.

The aim of this study is to evaluate the effectiveness of the implant diameter and length on force dissemination of tooth-implant and implant retained fixed restorations. A finite analysis model was used via a 3D simulation of a unilateral mandibular Kennedy Class I arch. Through thresholding the resultant assembly, a region of interest was selected from the computed tomography (CT) scan. Details of the diameter (D) and length (L) of implant were introduced. Ds used were 3.7, 4.7, and 5.7, while Ls used were 10, 11.5, and 13. The constant was the use of rigid connectors in both designs (implant-implant and implant-tooth fixed partial dentures [FPDs]) and the mesial implant (D 3.7 and L 11.5). Stress in cancellous bone around mesial abutment, which is the second premolar in tooth-implant FPD and mesial implant in the implant-implant FPD, revealed that the stress was significantly lower in tooth-implant FPD when compared with implant-implant FPD (21.1 ± 0.00 vs 46.1 ± 0.00, P < .001). Stress distribution in the bone around any implant depends on several factors such as diameter, length, and tooth-implant vs implant-implant support. The implant diameter was more significant for improved stress distribution than implant length. A moderate increase in the length of the implant consequently reduced stress.

Multiple Subchondral Bone Cysts Cause Deterioration of Articular Cartilage in Medial OA of Knee: A 3D Simulation Study.

AimsTo investigate the impact of subchondral bone cysts (SBCs) in stress-induced osseous and articular variations in cystic and non-cystic knee models using finite element analysis.Materials and Methods3D knee joint models were reconstructed from computed tomography (CT) and magnetic resonance imaging (MRI). Duplicate 3D models were also created with a 3D sphere mimicking SBCs in medial tibia. Models were divided into three groups. In group A, a non-cystic knee model was used, whereas in groups B and C, SBCs of 4 and 12 mm size were simulated, respectively. Cyst groups were further divided into three sub-groups. Each of sub-group 1 was composed of a solitary SBC in the anterior half of tibia adjacent to joint line. In sub-group 2, a solitary cyst was modeled at a lower-joint location, and in sub-group 3, two SBCs were used. All models were vertically loaded with weights representing double- and single-leg stances.ResultsDuring single-leg stance, increase in subchondral bone stress in sub-groups B-1 and B-3 were significant (p = 0.044, p = 0.026). However, in sub-group B-2, a slight increase was observed than non-cystic knee model (9.93 ± 1.94 vs. 9.35 ± 1.85; p = 0.254). All the sub-groups in group C showed significantly increased articular stress (p < 0.001). Conversely, a prominent increase in peri-cystic cancellous bone stress was produced by SBCs in groups B and C (p < 0.001). Mean cartilage shear stress in sub-groups B-1 and B-2 (0.66 ± 0.56, 0.58 ± 0.54) was non-significant (p = 0.374, p = 0.590) as compared to non-cystic model (0.47 ± 0.67). But paired cysts of the same size (B-3) produced a mean stress of 0.98 ± 0.49 in affected cartilage (p = 0.011). Models containing 12 mm SBCs experienced a significant increase in cartilage stress (p = 0.001, p = 0.006, p < 0.001) in sub-groups C-1, C-2, and C-3 (1.25 ± 0.69, 1.01 ± 0.54, and 1.26 ± 0.59), respectively.ConclusionThe presence of large-sized SBCs produced an increased focal stress effect in articular cartilage. Multiple cysts further deteriorate the condition by increased osseous stress effect and high tendency of peripheral cyst expansion in simulated cystic knee models than non-cystic knee models.

Biomechanical effects of corticotomy facilitated orthodontic anterior retraction: a 3-dimensional finite element analysis

The objective of this study was to assess the biomechanical effects of different corticotomy designs used for orthodontic anterior retraction through finite element analysis. Materials and methods: A basic finite element model simulating retraction of anterior teeth was built reversely from CBCT films of an adult patient with protruded maxillary anterior teeth. Another thirteen FE models were created according to different corticotomy designs varied with site width and the extent of incision. The initial displacement, Von Mises stress and pressure stress of dento-alveolar structures was computerized and analyzed. Results: Corticotomy can increase the initial displacement of anterior segment including teeth and surrounding alveolar bone, change the distribution of Von Mises stress in cancellous bone and the pressure stress in periodontal ligament of anterior teeth. When the incision was near the periphery of apical, the anterior segment showed the greatest displacement, the cancellous bone at either sockets or incision region showed the maximum stress. Bilateral incision combined with palatal incision showed approximate initial displacement and stress distribution with circumscribing incision. While the incision width increased, the biomechanical effects of corticotomy amplified. Conclusions: Varied corticotomy designs can change the biomechanical effects on dento-alveolar structures. The incision near the periphery of apical and bilateral incision combined with palatal incision may be the optimized design used for retraction of anterior teeth.

Implant stability in different implantation stages: Analysis of various interface conditions

Abstract After implant insertion, the functional loads enhance the integration between the implant and bone tissue. Analysis of load transfer in various stages of implantation is performed considering different types of contact conditions between implant and bone. An FE model of a threaded dental implant subjected to a buccolingual load of 100 N is developed. Different types of interface conditions, namely, frictionless, frictional, rough, and bonded are assessed to analyze peak stress and micromotions of implant and surrounding bones in different implantation stages. It is found that peak stress in implant, cortical bone, and cancellous bone decreases about 3%, 13%, and 29%, respectively, through the growth of friction coefficient from 0.05 to 0.7. Moreover, the maximum peak stress in implant and bones occurs in the frictionless type of contact. In this case, the force merely passes through under-pressure surfaces; therefore, it leads to intense stresses. The outcomes show that peak stress in cancellous bone is more sensitive to interface conditions than that in implant and cortical bone, so that its magnitude decreases approximately 68% by the change of contact condition from frictionless to bonded.