We study the strong 12 October 2021, MW\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$M_W$$\\end{document}=6.4, offshore Zakros, Crete earthquake, and its seismotectonic implications. We obtain a robust location (azimuthal gap equal to 17∘\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$^{\\circ }$$\\end{document}) for the mainshock by combining all freely available local, regional and teleseismic phase arrivals (direct and depth phase arrivals). Based on our location and the spatial distribution of the poor aftershock sequence we parameterise the fault area as a 30 km ×\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\ imes $$\\end{document} 20 km planar surface, and using three-component strong motion data we calculate slip models for both earthquake nodal planes. Our preferred solution shows a simple, single slip episode on a NE-SW oriented, NW shallow-dipping fault plane, instead of a N-S oriented, almost vertical nodal plane. An anti-correlation of the aftershocks spatial distribution versus the maximum slip (∼\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\\sim $$\\end{document} 27 cm) of our model further supports this, although the accuracy of the aftershock hypocentral locations could be somewhat questionable. Coulomb stress changes calculated for both kinematic models do not show substantial differences, as the aftershock seismicity within the first 3 months after the mainshock is distributed along the stress shadow zone and over the stress enhanced areas developed at the southern fault edge, induced by the mainshock. The Kasos island tide gauge record analysis shows a small signal after the earthquake, but it can hardly demonstrate the existence of tsunami waves due to the low signal-to-noise ratio. Tsunami simulations computed for the two nodal planes do not yield conclusive evidence to highlight whether the causative fault plane is NE-SW oriented, NW shallow-dipping plane, or the N-S oriented plane, nevertheless, the power spectrum analysis of the NW shallow-dipping nodal plane matches the spectral peak at 8 s period and is overall closer to the spectrum of the tide gauge record. A USGS Shakemap was also produced with all available local strong motion data and EMSC testimonies. This was also investigated in an effort to document the responsible fault. The overall analysis in this study, slightly suggests a rather westward, shallow-dipping offshore fault zone, being antithetic to the main Zakros almost vertical normal fault which shapes the coast of eastern Crete and is perpendicular to the direction of Ptolemy Trench in this area. This result agrees with seismotectonic and bathymetric evidence which support the existence of approximately N-S trending grabens, east and northeast of Crete.