Physical activity (PA) is known to be beneficial for mental health through decreasing depression and stress. In this study, we investigated the relationship between body composition, stress, depression, and self‐esteem with PA level. International Physical Activity Questionnaire (IPAQ)‐short form, Social Readjustment Rating Scale (SRRS), Stress Response Inventory (SRI), Beck Depression Inventory (BDI), and Self‐Esteem Scale (SES) were administered to perimenopausal women aged 45–55 and BMI≥23kg/m2. The PA level of the total group was 2406 MET‐min/week (n = 42). The PA level of overweight (23 kg/m2 ≤BMI<25 kg/m2) and obese (BMI≥ 25kg/m2) perimenopausal women was 1428 MET‐min/week and 2970 MET‐min/week (p<0.05), respectively. When three levels of PA (inactive, minimally active, and HEPA [Health‐enhancing physical activity] active) were analyzed, all levels consisted primarily of walking activities rather than vigorous activities. Within all groups, BDI, SRRS, and SRI scores were non‐significantly lower and SES was non‐significantly higher in HEPA active group versus other two groups. Anger (subscale of SRI) measures were lower among obese women and SES measures were higher in HEPA active group than others among overweight women (p<0.05). This study shows that the level of PA of Korean perimenopausal women was not insufficient, but the vigorous activity is thought to be necessary to enhance health. Health‐enhancing PA was related with high self‐esteem in overweight women and low anger in obese women. This study was supported by KyungHee University.