PurposeThe purpose of this study was to compare the predictive value of the valgus stress angle (SA), varus SA and varus-valgus SA difference (VVD) in predicting the degree of medial release in varus deformity during total knee arthroplasty (TKA).Materials and MethodsOne hundred eight TKAs (78 patients), which were performed in primary osteoarthritis with varus knee deformity, were retrospectively classified into three groups according to the degree of medial release (group A, mild release; group B, moderate release; and group C, severe release). Medical charts were reviewed, and long weight bearing standing anteroposterior radiographs and varus-valgus stress radiographs were evaluated.ResultsThe valgus SA was significantly different between group A and B and between group A and C. However, it was not significantly different between group B and C. The varus SA was significantly different between group B and C and between group A and C. However, it was not significantly different between group A and B. The VVD was significantly different in all intergroup comparisons.ConclusionsEvaluation of the VVD is more valuable in predicting the degree of medial release in TKA performed in varus knee deformity than evaluation of the simple valgus and varus SA.