Street Children's Hospital Research Articles

Coordinated ultrasound screening of infants: Hungry experience

Objective: In 1990, three hospitals (the Madarász Street Children's Hospital in Budapest and the general hospitals in Cegléd and Zalaegerszeg) organised a coordinated ultrasound (US) screening programme. The screening was aimed at detecting a predefined series of developmental and acquired disorders. Material: In 9 years, a total of 46 858 infants were screened by the three hospitals: 20 185 in Budapest, 13 258 in Cegléd and 12 415 in Zalaegerszeg. Results: Disorders were detected in 4068 cases. Most (2885) involved abdominal or renal disorders; intracranial anomalies were found in 1062, and the remaining discoveries were of cysts or tumours in the liver, spleen or ovaries. Conclusions: Many disorders were detected (8.7%) needing either follow-up, or some form of treatment.

Charles Dickens' work to help establish Great Ormond Street Hospital,London

When teaching our students about the medical ramifications of poverty and the importance of child advocacy, we could do no better than to point them in the direction of Charles Dickens (figure 1), England's celebrated novelist and social reformer. The reading of just a few of his novels, and the biting essays he composed for his weekly magazines, Household Words (1850–58) and All the Year Round (1859–70), shows that rarely have children had a more eloquent or effective proponent. Here I shall discuss one example of Dickens' broad-based activism on behalf of children—the establishment of London's Great Ormond Street Children's Hospital. 1 Kosky J Mutual friends. Charles Dickens and the Great Ormond Street Children's Hospital. St Martin's Press, New York1989 Google Scholar I choose this episode from his life because it exemplifies so well his deep sense of civic responsibility, his love of children, and his keen understanding of the need for a special place to care for sick children. It is also an exemplary model of conduct in health-care advocacy for today's medical professional.

Chloroquine-Chlorpheniramine Interaction In Human Malaria

The purpose of this study was to examine the effect of chloroquine-chlorpheniramine (CQ-CP) combination therapy on the efficacy and disposition of chloroquine (CQ) in acute uncomplicated malaria. A 3-day standard treatment with 25 mg CQ base per kilogram body weight alone or in combination with chlorpheniramine (CP) was orally administered to 17 semi-immune Nigerian children with Plasmodium falciparum parasitemia, attending the Massey Street Children's Hospital, Lagos, Nigeria. Parasitemia was determined on thick blood films stained with Giemsa, and treatment failures were established following the WHO classification for CQ resistance. Whole blood CQ concentrations were monitored at pre-determined intervals during the 28 days of follow-up using blood dried on filter-paper. Treatment with CQ-CP combination resulted in a shorter parasite clearance time (2.0 ± 0.5 d) & a higher cure rate (87.5%) compared to treatment with CQ alone (3.5 ± 0.5 d; 66.7%). CQ pharmacokinetic parameters: maximum drug concentration (Cmax) and the area under the first-moment drug-concentration-time curve (AUMC) were significantly increased (p < 0.01; p < 0.001 respectively) by CP administration while the time to achieve the peak was reduced in the presence of CP. We conclude that administration of CP increased CQ uptake as judged by an increase in the maximum concentration (Cmax) and a decrease in the time to attain the concentration (Tmax), as well as an increase in the area under the curve, which signifies increased systemic availability of CQ in the presence of CP. Nigerian Quarterly Journal of Hospital Medicine Vol.9, No.3 (1999) pp. 225-230

Ultrasonography in the evaluation of neck abscesses in children.

A prospective study evaluating the benefits of preoperative ultrasonography of paediatric neck abscesses is presented. Twenty-three consecutive children who presented with suspected neck abscesses to the Accident and Emergency Department at the Temple Street Children's Hospital between 1990 and 1992 have been evaluated prospectively. On admission, ultrasonography showed a collection of pus in 11 children and these underwent incision and drainage. The other 12 had intravenous antibiotics. Six of these remained pyrexial and had a repeat ultrasound after 72 h revealing pus which was drained. The remaining were managed successfully with medical treatment. In this study there were no negative surgical interventions and we recommend ultrasonography for preoperative evaluation of children with suspected inflammatory neck abscesses.

Left sided appendiceal Mitrofanoff channel.

British Journal of UrologyVolume 78, Issue 1 p. 133-134 Left sided appendiceal Mitrofanoff channel D.T. Wilcox MD, FRCS, Senior Registrar., D.T. Wilcox MD, FRCS, Senior Registrar. Department of Paediatric Urology, Great Ormond Street Children's Hospital NHS Trust, London, UKSearch for more papers by this authorR. Ghavamian MD, Senior Registrar., R. Ghavamian MD, Senior Registrar. Department of Paediatric Urology, Great Ormond Street Children's Hospital NHS Trust, London, UKSearch for more papers by this authorP.G. Duffy MB, FRCS (I), Consultant., P.G. Duffy MB, FRCS (I), Consultant. Department of Paediatric Urology, Great Ormond Street Children's Hospital NHS Trust, London, UKSearch for more papers by this author D.T. Wilcox MD, FRCS, Senior Registrar., D.T. Wilcox MD, FRCS, Senior Registrar. Department of Paediatric Urology, Great Ormond Street Children's Hospital NHS Trust, London, UKSearch for more papers by this authorR. Ghavamian MD, Senior Registrar., R. Ghavamian MD, Senior Registrar. Department of Paediatric Urology, Great Ormond Street Children's Hospital NHS Trust, London, UKSearch for more papers by this authorP.G. Duffy MB, FRCS (I), Consultant., P.G. Duffy MB, FRCS (I), Consultant. Department of Paediatric Urology, Great Ormond Street Children's Hospital NHS Trust, London, UKSearch for more papers by this author First published: July 1996 https://doi.org/10.1046/j.1464-410X.1996.13128.xCitations: 1 Mr P.G. Duffy Department of Paediatric Urology, Great Ormond Street Children's Hospital NHS Trust, Great Ormond Street, London WC1N 3JH, UK. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article.Citing Literature Volume78, Issue1July 1996Pages 133-134 RelatedInformation

Jules Kosky, Mutual friends: Charles Dickens and Great Ormond Street Children's Hospital, London, Weidenfeld &amp; Nicolson, 1989, 8vo, pp. x, 245, illus., £14.95.

Jules Kosky, Mutual friends: Charles Dickens and Great Ormond Street Children's Hospital, London, Weidenfeld &amp; Nicolson, 1989, 8vo, pp. x, 245, illus., £14.95.