The purpose of this study is to forecast the spatial distribution of diagenetic facies (DF) of tight sandstone in the offshore sparse wells area. Analytical test data, rock physics experiment data and prestack seismic data were used to study the spatial distribution of seismic diagenetic facies (SEISDF) of tight sandstone of the second (H4b) submember of the fourth (H4) member of the Huagang (E3h) Formation in the N gas-field, Xihu Depression, East China Sea Basin. Based on diagenesis and diagenetic minerals, core-based DF of the H4b sandstone were divided into chlorite-coated facies (CHF), calcite-cemented facies (CAF), dissolution facies (DIF), tightly compacted facies (TIF), and quartz-cemented facies (QUF). Various seismic elastic parameters were obtained by prestack elastic parameter inversion method, and sensitive seismic elastic parameters were selected according to the seismic identification principle of DF. In order to predict the spatial distribution of DF, four DF and sensitive seismic elastic parameters were integrated to establish a SEISDF prediction model based on supervised learning, and obtain a diagenetic facies comprehensive index (DFCI) that can distinguish four DF. Then, the 90° phase conversion technique of seismic lithology was used to realize the consistency of the DFCI between isochronous stratigraphic interfaces with core-based DF. The stratal slicing technique of seismic geomorphology was used to make stratal slices of the DFCI between isochronous stratigraphic interfaces. Representative stratal slices were singled out, and the spatial distribution of the SEISDF was interpreted. This study shows that the H4b1 sublayer primarily develops the TIF, while the H4b2 and H4b3 sublayers chiefly develop the QUF, CHF, and DIF. Compared with the H4b2 and H4b3 sublayers, the areas of the QUF and DIF in the H4b4, H4b5, and H4b6 sublayers slightly increase. The QUF are mainly distributed in the subaqueous distributary channel and a small number of sheet sand and channel bar depositional facies in the form of continuous sheets. The CHF are primarily developed in lenticular shape in the channel bar and a small amount of sheet sand and subaqueous distributary channel depositional facies. The most favorable DIF are chiefly developed in the subaqueous distributary channel, channel bar, and sheet sand depositional facies near the fault, which are distributed in strips. This study proposes a very valuable method for the SEISDF prediction of tight sandstone, which can provide a reference for the study of DF of similar strata in other sedimentary basins.