The safety of aging structures over the course of their service life is given by structural reliability. Additionally, there is a lack of techniques available for processing raw structural health monitoring (SHM) data in a way that makes it possible to validate and/or update structural reliability. Along with the diagnosis of structural anomaly using SHM techniques, the prognosis of structural condition is also an important aspect. Field-measured strain responses can be used as an indication of structural safety and provide information regarding the load-carrying capacity of the structure. Reliability assessment can be conducted only if a more accurate digital analogue is obtained for the actual bridge and when the structural responses can be predicted accurately. This paper validates a digital model of a real-life railway truss bridge. Pamban bridge is a century-old railway bridge having one track and four internally statically determinate truss leaves. Electrical strain gauges are instrumented to measure the axial strain responses in 84 out of 92 members of the bridge. Strain responses of 1072 train movements that traversed the bridge from 1st January 2021 to 14th July 2021 are recorded, and root mean square error (RMSE) between these field-measured strain responses and analytically computed strain responses from the digital model are estimated. The stationary trend of the time history of RMSE values depicts constant structural reliability. A technique is also proposed to forecast structural strain responses, which is validated with field-measured strain responses.