AbstractFor the purpose of estimating the earthquake response, particularly the story drift demand, of reinforced concrete (R/C) buildings with proportional hysteretic dampers, an equivalent single‐degree‐of‐freedom (SDOF) system model is proposed. Especially in the inelastic range, the hysteretic behavior of an R/C main frame strongly differs from that of hysteretic dampers due to strength and stiffness degradation in R/C members. Thus, the proposed model, unlike commonly used single‐spring SDOF system models, differentiates the restoring force characteristics of R/C main frame and hysteretic dampers to explicitly take into account the hysteretic behavior of dampers. To confirm the validity of the proposed model, earthquake responses of a series of frame models and their corresponding equivalent SDOF system models were compared. 5‐ and 10‐story frame models were studied as representative of low‐ and mid‐rise building structures, and different mechanical properties of dampers—yield strength and yield deformation—were included to observe their influence on the effectiveness of the proposed model. The results of the analyses demonstrated a good correspondence between estimated story drift demands using the proposed SDOF system model and those of frame models. Moreover, the proposed model: (i) led to better estimates than those given by a single‐spring SDOF system model, (ii) was capable of estimating the input energy demand and (iii) was capable of estimating the total hysteretic energy and the participation of dampers into the total hysteretic energy dissipation, in most cases. Results, therefore, suggest that the proposed model can be useful in structural design practice. Copyright © 2010 John Wiley & Sons, Ltd.