Alternate Room-Pillar Mining Method with Ascending Backfill is now used in deep mining of Sanshandao Gold Mine. In mining practice of the metal mines, the widths of the room and pillar vary from 6m to 15m. In order to improve the production capacity and solve the deep mining safety problems, a fuzzy optimization model containing 11 evaluation indexes was built to choose the optimal structural parameters among 8m×8m, 8m×10m, 10m×10m, 10m×12m and 12m×12m. The fuzzy comprehensive evaluation results prove that the optimal stope structural parameter is 10m×10m for safety and high efficiency mine operation.