Stone Score Research Articles

Percutaneous nephrolithotomy in patients with spinal cord injury: should all these patients be automatically assigned a Guy's stone score of 4?

To assess the complication and stone-free rates of PCNL in patients with spinal cord injury (SCI) and to evaluate whether this population should be assigned a Guy's stone score (GSS) of 4. A case-control study was conducted, and electronic charts were reviewed to search for patients with SCI, bladder dysfunction, and kidney stones who had undergone PCNL. Control cases were randomly selected from among patients with complete staghorn calculus (GSS = 4). One hundred and seventeen patients were included. Patients with SCI had a significant shorter operative time (119 vs. 141min; p = 0.018). There were no significant differences between the groups in terms of the patients' position, number of renal tracts, bleeding or transfusion rate; however, there was a significantly higher complication rate (23.1% vs. 7.8%; p = 0.009) and a longer hospital stay (5.8 vs. 3.1days; p = 0.002) among patients with SCI. With regards to the stone-free rate in patients with different grades of GSS patients with SCI who had a GSS of 1 had a stone-free rate of 85.7%, while those with a GSS of 2, 3, or 4 had 50%, 50%, and 31.5%, respectively (p = 0.024). Only patients with a GSS of 4 in the SCI group had outcomes that were similar to those of control patients (31.5% vs. 31.6%). Patients with SCI should not be automatically assigned GSS 4. Stone-free rate is related to stone burden in these patients, although they do show a higher complication rate and a longer hospital stay than non-neurological patients.

Percutaneous Nephrolithotomy in Paediatric Population: A Single Center Experience.

Management of paediatric stone disease is challenging as they are considered high risk group. Percutaneous nephrolithotomy is minimally invasive procedure with definite advantages in terms of higher stone clearance in single session and no long term effect in renal function. Retrospective study was done including all patients upto the age of 18 years who underwent Percutaneous nephrolithotomy from January 2010 to December 2018 in our center after taking approval from ethical committee. Data was collected regarding gender, operative side, operative time duration, hospital stay, post-operative decrease in hemoglobin, stone size, Guy's stone score and early post-operative complications with Clavien-Dindo grade. Percutaneous nephrolithotomy was done in 48 renal units in 44 patients. 28 patients were boys and 16 were girls with mean age of 10.91 ± 5.22 years and mean stone size 17.16 ± 6.43 mm. 91.6% of cases had Guy's stone score of 1 and 2. Standard percutaneous nephrolithotomy was done in 21 renal units, mini percutaneous nephrolithotomy in 24 renal units and supermini percutaneous nephrolithotomy was done in three renal units with total stone free rate of 93.4%. Three patients required extracorporeal shockwave lithotripsy for significant residual stone. Average post-operative hemoglobin drop was 1.2 gm%. Overall complications rate was 18.1% with 4.5% of complications being grade 1 and 2 whereas 13.6% were Grade 3. Percutaneous nephrolithotomy is safe and feasible in paediatric patients with large stone burden, complex anatomy or shock-wave lithotripsy failure with acceptable complication and stone free rate.

Pneumatic Lithotripsy versus Holmium Laser Lithotripsy in Percutaneous Nephrolithotomy for Patients with Guy’s Stone Score Grade IV Kidney Stone

Background and Objective: The aim of this study was to compare the efficacy and reliability of holmium (Ho:YAG) laser lithotripsy (HLL) and pneumatic lithotripsy (PL) in percutaneous nephrolithotomy (PCNL) in the treatment of patients with Grade IV kidney stones based on Guy’s Stone Score. Study Design/Materials and Methods: This retrospective study included 103 patients with Grade IV kidney stones out of 440 patients who underwent PCNL through HLL and PL in Second Affiliated Hospital of Shantou University Medical College, China, from January 2016 to December 2018. We analyzed preoperative, intraoperative, and postoperative variables of the patients to evaluate the efficacy and reliability of PCNL procedures. Results: Patients were categorized as Grade I, II, III, and IV, and the patients of each grade were 85 (19.32%), 39 (8.86%), 213 (48.41%), and 103 (23.41%), respectively. In Grade IV, the total operative time (min) for the PL and HLL groups was 137.7 ± 47.79 and 134.27 ± 53.38, respectively (p = 0.744). The variation in laboratory examination values including ΔHGB (g/L), ΔHCT, ΔPCT, and ΔCr (μmol/L) for PL and HLL groups was 19 ± 11.23/12 ± 15.42 (p = 0.012), 0.057 ± 0.034/0.038 ± 0.045 (0.009), 0.027 ± 0.034/0.026 ± 0.034 (0.702), and 3.07 ± 17.4/20.54 ± 65.93 (0.692), respectively. The postoperative hospitalization day was 8.94 ± 4.2 and 7.73 ± 2.75 (p = 0.015), respectively. As for the stone-free rate (SFR), the SFRs for PL and HLL were 48.15% (n = 39/81) and 59.09% (n = 13/22) (p = 0.363), respectively. Conclusions: HLL showed a comparable advantage of not only decreased postoperative hemoglobin and hematocrit but also fewer postoperative hospitalization days. Based on the results of our retrospective study, for those Grade IV kidney stone patients who have a risk of bleeding before PCNL operation, HLL can be a considerable treatment option. Besides, in consideration of reducing human care cost, HLL which showed fewer hospitalization days, would be more welcome by patients.

A Comprehensive Comparison of Guy’s Stone Score, CROES Nomogram, S.T.O.N.E. Nephrolithometry, and the Seoul Renal Stone Complexity Scoring System in Predicting Perioperative Outcomes after Percutaneous Nephrolithotomy

Background: Various nephrolithometry scoring systems (NSS) are proposed to determine the structural configuration of kidney stones. Nevertheless, evidence of the comparison among these scoring systems in anticipating postoperative outcomes after percutaneous nephrolithotomy (PCNL) are limited. Objective: To compare the correlation of four NSS with stone-free rates and perioperative results following PCNL. Materials and Methods: The authors examined a retrospective study of patients with kidney stones who received PCNL. One hundred seventy-two patients admitted for surgery at Ramathibodi Hospital were assessed. Four NSS were compared, Guy’s Stone Score (GSS), the Clinical Research Office of the Endourological Society nephrolithometric nomogram (CROES), S.T.O.N.E. Nephrolithometry (STONE), and the Seoul National University Renal Stone Complexity (S-ReSC) scoring system. The authors evaluated the correlations between these four scoring systems with stone-free rates and postoperative outcomes. Results: The stone-free status was 53.5%. There were significant differences in the mean scores of the four systems between the stone-free group and the not stone-free group (1.97 versus 3.70, p<0.05 in GSS; 242.40 versus 159.28, p<0.05 in CROES; 6.64 versus 9.08, p<0.05 in STONE; and 3.44 versus 8.41, p<0.05 in S-ReSC). Multivariate analysis revealed only S-ReSC as independent preoperative factors for PCNL success (p<0.001). Moreover, each scale had a significant correlation with blood loss, length of hospital stay, and operative time. Three scoring systems, all except STONE, were significantly associated with percentage change in estimated glomerular filtration rates (eGFR). There was no significant association among all four scoring systems with postoperative complications. Conclusion: All four NSS represent excellent predictors for stone-free rates and correlate well with surgical outcomes. Keywords: GSS, CROES, STONE, S-ReSC, Percutaneous nephrolithotomy

Preoperative risk factors for complications of percutaneous nephrolithotomy.

This study was conducted to evaluate preoperative risk factors for development of complications of percutaneous nephrolithotomy (PCNL). All consecutive patients aged ≥ 16years who underwent PCNL during 2015 were retrospectively reviewed. Non-contrast CT (NCCT) was performed for all patients to evaluate stone complexity. The technique of PCNL was the same for all patients. Intra-operative and postoperative complications were recorded and classified based on modified Clavien system. The differences in preoperative data (patients, renal and stone characteristics including Guy's and STONE scores) between complicated and uncomplicated cases were compared using univariate and multivariate statistical analyses for detection of independent risk factors. The study included 1178 patients (61% were males). Mean age was 50 ± 12years, and mean BMI was 30.7 ± 5.7kg/m2. Complicated group included 166 patients (14.1%). Independent risk factors on multivariate analysis were infected preoperative urine culture (RR: 2.098, P 0.001, 95%CI: 1.380-3.189), largest stones diameter 30mm or more (RR: 2.481, P > 0.001, 95%CI: 1.697-3.627) and number of calyces affected by the stones (RR: 2.431, P 0.002, 95%CI: 1.400-4.222 for affection of two calyces and RR: 2.778, P 0.005, 95%CI: 1.357-5.684 for affection of three calyces). While two scoring systems (Guy's and STONE) were not predictive of complications after PCNL, preoperative risk factors were infected preoperative urine culture, distribution of the stones or stone branches in two or three calyceal groups and stone size 30mm or more.

Safety of Upper Pole Puncture in Percutaneous Nephrolithotomy with the Guidance of Ultrasonography versus Fluoroscopy: A Comparative Study

Introduction: The aim of this study was to compare the safety of ultrasonography-guided (UG) puncture and fluoroscopy-guided (FG) upper pole access (UPA) in percutaneous nephrolithotomy (PCNL). Methods: Consecutive patients with a solitary UPA were enrolled into the study from 2012 to 2020 and analyzed in a retrospective manner. In total, 177 patients were divided into 2 groups according to the method during the puncture phase of the access: FG (n = 105) and UG (n = 72). The UG and FG groups were compared in terms of complications (i.e., pleural injury and blood transfusion rate) and surgical outcomes. Results: Gender, side, grade of hydronephrosis, type of access (i.e., supracostal vs. subcostal), Guy’s stone score, age, stone diameter, skin-to-stone distance, and stone density were similar in the 2 groups (p > 0.05). Only in 25.9% of cases, UPA was done using a subcostal approach. The overall complication rates were similar between the groups (p > 0.178). For the UG and FG groups, the rate of pleural injury (8.5 vs. 4.1%) and the blood transfusion rate (8.5 vs. 2.8%) were also similar (p > 0.05). The fluoroscopy time and mean hemoglobin drop were significantly lower in the UG group than in the FG group (134.2 vs. 82.2 s, respectively, p = 0.001; 20.8 ± 9.8 vs. 16.8 ± 7.9 g/L, respectively, p = 0.001). Stone-free rate (SFR) was also similar in the FG and UG groups (77.1 vs. 75.0%, respectively, p = 0.742). Conclusion: While it is commonly expected that the complication rates are lower in UG puncture for UPA in PCNL than they are in FG puncture, the present study failed to show this difference. However, the radiation exposure time seemed to be lower in UG puncture than FG puncture and had a similar stone-free rate (SFR) for UPA in PCNL.

External validation of STONE, modified STONE, and CHOKAI scores for the diagnosis of ureteral stones in the Turkish population

Background:Scoring systems seem to be effective in the management of patients with uncomplicated ureteral stones. However, their efficiency may differ by population.Objectives:We aimed to validate ...

External validation of STONE, modified STONE, and CHOKAI scores for the diagnosis of ureteral stones in the Turkish population

Background: Scoring systems seem to be effective in the management of patients with uncomplicated ureteral stones. However, their efficiency may differ by population. Objectives: We aimed to validate STONE, modified STONE, and CHOKAI scores for the diagnosis of ureteral stones in the Turkish population. Methods: We conducted a retrospective chart review between 01 February 2018 and 30 November 2018, in an academic emergency department. Demographics, laboratory findings, and radiologic tests of patients with flank pain were obtained. Computed tomography was used as the gold standard for the diagnosis of ureteral stones. STONE, modified STONE, and CHOKAI scores were calculated for each patient. The performance of the scoring systems was compared in terms of their specificity, sensitivity, positive likelihood ratio, negative likelihood ratio, negative predictive value, and positive predictive value. Results: A total of 157 patients were included in the study. The mean age was 38.47 ± 14.87 years, and 103 (65.6%) of the patients were males. The prevalence of ureteral stones was 84.0%, 88.9%, and 85.0% in the high-risk patients and 12%, 9.4%, and 22.7% in the low-risk patients for the STONE, modified STONE, and CHOKAI scores, respectively. Area under the curve values for the STONE, modified STONE, and CHOKAI scores were 0.776 (p = 0.001; 0.692–0.860 95% confidence interval), 0.825 (p < 0.001; 0.749–0.901 95% confidence interval), and 0.869 (p < 0.001; 0.806–0.932 95% confidence interval), respectively. The specificity and sensitivity values of STONE, modified STONE, and CHOKAI scores for the diagnosis of ureteral stones were 64.71, 71.70; 70.59, 87.74; and 66.67, 90.57, respectively. Conclusion: The CHOKAI score displayed the best performance compared to STONE and modified STONE in diagnosing ureteral stones in the Turkish population.

667 - Do the scoring systems predict the success of percutaneous nephrolithotomie for staghorn stones? Comparison of 4 scores: The Guy’s stone score, STONE Score, CROES nomogram and S-ReSC score

667 - Do the scoring systems predict the success of percutaneous nephrolithotomie for staghorn stones? Comparison of 4 scores: The Guy’s stone score, STONE Score, CROES nomogram and S-ReSC score

The Pros and cons of balloon dilation in totally ultrasound-guided percutaneous Nephrolithotomy

BackgroundTo evaluate the feasibility and safety of balloon dilation (BD) in totally ultrasound-guided percutaneous nephrolithotomy (PCNL).MethodsThe data of 95 patients underwent BD were collected in this retrospective study between August 2016 and December 2018. During the same period, telescopic metal dilation was used in 1161 patients. Ninety five patients were selected as the control group and matched at a 1:1 ratio to index balloon dilation (BD) cases in regards to Guy’s stone score, age, sex, BMI, degree of hydronephrosis and stone area. Peri-operative data were compared between the two groups.ResultsTotal operative time was significantly shorter in the BD group (62.2 ± 22.4 min vs. 70.2 ± 25.8 min, p = 0.024). Tract establishment time was significantly shorter in the BD group (3.4 ± 1.8 min vs. 4.3 ± 2.3 min, p < 0.001). The success rate of tract dilation by first attempt was higher in the TMD group compared with that of BD group; however the difference was not statistically significant. There was no significant difference between groups with regards to complication and stone-free rates. The cost of PCNL in the BD group was significantly higher than that of the TMD group (US $4831.4 ± 1114.8 vs. US $4328.4 ± 975.7, p = 0.012). Subsequent analysis revealed that mild or no hydronephrosis were risk factor for failure of balloon dilation under ultrasound.ConclusionsBD has acceptable complication and stone free rates compared with those in TMD; however, BD under ultrasound is not suggested for stone cases without hydronephrosis.

Novel prediction scoring system for simple assessment of stone-free status after flexible ureteroscopy lithotripsy: T.O.HO. score.

To develop a novel simple quantitative scoring model for predicting stone-free status after a flexible ureteroscopy lithotripsy procedure by standardizing the complexity of ureteral stone characteristics. We retrospectively reviewed 586 patients with renal or ureteral stones who underwent flexible ureteroscopy lithotripsy at Abiko Toho Hospital, Chiba, Japan, from 2015 to 2018. Multivariate regression was applied to examine the relationship between preoperative descriptors and stone-free status, and a nomogram was developed using significant predictors. Next, the individual components of the nomogram were assigned points to form a simple scoring system. The predictive performance of this new scoring system was compared with the STONE score at optimal cut-off values using receiver operating characteristic curve and area under the curve analyses. Multivariate logistic regression findings showed that factors associated with stone-free status were length, Hounsfield unit and stone location. A nomogram prediction model was developed with an area under the curve value of 0.845, then consequently used to develop a new simple score system termed the T.O.HO. score consisting of three stone characteristics: (T)allness (1-5points), (O)ccupied lesion (1-3points) and (HO)unsfield units evaluation (1-3points). The T.O.HO. score was significantly higher in stone remaining (7.66) than stone-free (5.27; P<0.001) cases. The area under the curve for the T.O.HO. score was 0.833 at an optimal cut-off value of 7, whereas that for the STONE score was 0.683 at an optimal cut-off value of 9, showing the superiority of this new scoring system. The T.O.HO. score is a useful tool for predicting stone-free status in patients who have undergone a flexible ureteroscopy lithotripsy procedure.

Evaluation of Nephrolithometric Scoring Systems to Predict Outcomes of Retrograde Intrarenal Surgery.

The aim of the study was to evaluate the predictive value of nephrolithometric scoring systems used to predict the complexity of renal stones for the outcomes of retrograde intrarenal surgery (RIRS). A total of 81 patients who underwent RIRS for nephrolithiasis between January 2013 and October 2017 were reviewed in this retrospective study. Guy's Stone Score (GSS), the S.T.O.N.E., Clinical Research Office of the Endourologic Society (CROES), and Seoul National University Renal Stone Complexity (S-ReSC) nephrolithometry scores were assessed by same researcher for each patient from preoperative non-contrast enhanced computed tomography scans. These nephrolithometric scores, stone characteristics and complications were compared in patients with/without residual stone. The median (IQR) age of patients (37 female/44 male) was 45 (20) years. The median (IQR) stone burden was 139.4 (125.4) mm2 and the mean Hounsfield unit (HU) value was 1034.46 ± 239.56. The stone burden, S.T.O.N.E. and S-ReSC scores were statistically significantly higher and the CROES score was significantly lower in patients with a residual stone (p < 0.001, for all). The incidence of residual stones was statistically significantly higher in patients with Grade 3 GSS (p = 0.018). While S.T.O.N.E., S-ReSC and CROES were significantly correlated with stone-free rates, GSS failed to correlate with stone-free status. According to the receiver operating characteristic (ROC) curve analysis, the predictive value of stone burden was higher for residual stones, compared to S-ReSC scoring (p < 0.05). Nephrolithometric scoring systems nomograms used to predict the PCNL success were not superior to stone burden in predicting the RIRS success.

Critical Application of Adult Nephrolithometric Scoring Systems to Children Undergoing Mini-Percutaneous Nephrolithotomy.

Objective: To evaluate and compare the ability of the Guy's stone score (GSS), the S.T.O.N.E. nephrolithometry, and the Clinical Research Office of the Endourology Society (CROES) nomogram to predict the outcome of mini-percutaneous nephrolithotomy (MPNL) in children, and to identify which of the predictors involved in these scoring systems can separately affect this outcome. Patients and Methods: All children younger than 14 years who had MPNL in our center over a period of 3 years were included prospectively. Bivariate analyses were done to evaluate the associations of the three scoring systems and the predictors composing them with single-session stone clearance and complications. Receiver operating characteristic (ROC) curve analyses of the three scoring systems were conducted to evaluate and compare their abilities to predict the outcomes. Decision curve analyses for the three scoring systems were conducted to evaluate the clinical benefit of using each of them to predict stone clearance. Results: We consecutively enrolled 92 renal units in 89 children with a median age of 9.5 years. Single-session stone clearance was achieved in 76 (82.6%) renal units. Complications occurred with 19 (20.7%) procedures. Stone multiplicity (p = 0.043), staghorn stone (p = 0.007), prior stone treatment (p < 0.001), number of calices involved (p = 0.006), stone burden (p = 0.003), GSS (p < 0.001), S.T.O.N.E. nephrolithometry (p = 0.012), and CROES nomogram (p < 0.001) had significant associations with stone clearance. Only stone attenuation was significantly associated with complications (p = 0.031). For prediction of stone clearance, CROES nomogram demonstrated the greatest area under the ROC curve and the greatest net benefit on decision curve analyses. Conclusions: For children undergoing MPNL, CROES nomogram is the best to predict stone clearance. However, none of the studied scoring systems predicted complications efficiently.

Guy’s Stone Score as a Predictor for Stone-Free Rate and Complications in Percutaneous Nephrolithotomy: A Single-Center Report from a Stone Belt Country

Objectives: To evaluate Guy’s Stone Score (GSS) as a grading system for the complexity of renal calculi before percutaneous nephrolithotomy (PCNL) and as a predictor for stone-free rate (SFR) and potential complications in the setting of a developing country with many cases of advanced complex stone disease. Patients and Methods: We performed a prospective study on 115 patients with renal stones who had PCNL between August 2017 and October 2018. Stone complexity was classified according to GSS using preoperative imaging. The rates of perioperative complications were assessed using the Clavien grading system, and the SFR was assessed in the 3rd postoperative week by abdominal X-ray and renal ultrasound. The χ² and one-way ANOVA tests were used for statistical analysis. A p value ≤0.05 was considered significant. Results: The study included 115 patients (77 males) with a mean age of 50.2 (±13.3) years. Cases were classified according to GSS into 4 grades; there were 24 (20.9%) grade I, 48 (41.7%) grade II, 25 (21.7%) grade III, and 18 (15.7%) grade IV cases. There was a significant inverse correlation between GSS grade and SFR (p < 0.001). The rate of complications using the Clavien grading system were significantly higher in GSS grades III and IV (p = 0.002). So were the rates of blood transfusion, the need for >1 access tract, and the duration of hospitalization. Conclusion: GSS is a simple and easily reproducible system to classify the complexity of renal stones. In our setting, it also proved an excellent tool to predict SFR, perioperative complications, and associated ancillary procedures. Ultimately, it can help surgeons and, above all, patients to make a more informed decision about their surgery.

MP63-06 PREDICTING THE POSTOPERATIVE OUTCOME OF PERCUTANEOUS NEPHROLITHOTOMY WITH MACHINE LEARNING SYSTEM: SOFTWARE VALIDATION AND COMPARATIVE ANALYSIS WITH GUY’S STONE SCORE AND THE CROES NOMOGRAM

You have accessJournal of UrologyStone Disease: Surgical Therapy VI (MP63)1 Apr 2020MP63-06 PREDICTING THE POSTOPERATIVE OUTCOME OF PERCUTANEOUS NEPHROLITHOTOMY WITH MACHINE LEARNING SYSTEM: SOFTWARE VALIDATION AND COMPARATIVE ANALYSIS WITH GUY’S STONE SCORE AND THE CROES NOMOGRAM Alireza Aminsharifi*, Dariush Irani, Sona Tayebi, Tayebeh Shabanian, and Mehdi Parsaei Alireza Aminsharifi*Alireza Aminsharifi* More articles by this author , Dariush IraniDariush Irani More articles by this author , Sona TayebiSona Tayebi More articles by this author , Tayebeh ShabanianTayebeh Shabanian More articles by this author , and Mehdi ParsaeiMehdi Parsaei More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000938.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To validate the output of a machine learning-based software as an intelligible interface for predicting multiple outcomes after percutaneous nephrolithotomy (PCNL). We compared the performance of this system with Guy’s stone score (GSS) and the Clinical Research Office of Endourological Society (CROES) nomogram. METHODS: Data from 146 adult patients (87 males, 59%) who underwent PCNL at our institute were used, and preoperative variables and postoperative outcomes were recorded. Stone-free status was determined by computed tomography scan postoperatively. Preoperative data were consecutively imported into the software and its output was extracted. To validate the system, accuracy of the software for predicting each postoperative outcome was compared to the actual outcome. Similarly, preoperative data were analyzed with GSS and CROES nomograms to determine stone-free status as predicted by these nomograms, and the predictive performance of these two systems was calculated. A receiver operating characteristic (ROC) curve was generated for each scoring system, and the area under curve (AUC) was calculated and used to assess the predictive performance of the nomograms versus ANN software. RESULTS: Overall stone-free rate (SFR) was 72.6% (106/146). Forty of 146 patients (27.4%) were scheduled for Forty-two ancillary procedures (shock wave lithotripsy (SWL) (n= 31) or repeat PCNL (n=11)) to manage residual renal stones. Overall, the machine learning system predicted the PCNL outcomes with an accuracy ranging between 80% and 95.1%. A higher GSS grade and lower CROES nomogram score were significantly associated with lower SFR (p=0.01 and p= 0.03, respectively). When ROC curves were plotted for each predictive model for stone-free status, the area under the ROC curve for ANN software (0.915) was significantly larger than the AUC for GSS (0.615) or CROES nomograms (0.621) (p<0.001) (Figure 1). CONCLUSIONS: At the internal institutional level, the machine learning-based software was a promising tool for recording, processing and predicting outcomes after PCNL. Validation of this system against an external dataset is highly recommended before its widespread application. Source of Funding: Shiraz University of Medical Sciences. © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e956-e956 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alireza Aminsharifi* More articles by this author Dariush Irani More articles by this author Sona Tayebi More articles by this author Tayebeh Shabanian More articles by this author Mehdi Parsaei More articles by this author Expand All Advertisement PDF downloadLoading ...

Application of decision rules on diagnosis and prognosis of renal colic: a systematic review and meta-analysis.

Renal colic is a prevalent emergency department presentation resulting from urolithiasis. Clinical decision rules for the diagnosis of urolithiasis were developed to help clinicians with better judgment. In this systematic review, we assessed the performance of prediction rules on urolithiasis diagnosis and prognosis. MEDLINE, Embase, Web of Science, and Scopus were searched for studies on the performance of a clinical decision tool for diagnosis or prognosis of urolithiasis. Performance and accuracy of the rules were the key outcomes of interest. Databases were searched from inception to March 2019. Of the 4980 articles reviewed, 28 studies were included in the present analysis. Twenty-one studies were on urolithiasis diagnosis (including eight studies on STONE rule), and 10 studies reported urolithiasis outcomes. Studies were at low to moderate risk of bias. The pooling of data on STONE showed that the prevalence of urolithiasis in low, moderate, and high risk groups were: 12% (95% confidence interval 9%-15%), 53% (95% confidence interval 43%-62%), and 83% (95% confidence interval 75%-91%), respectively. In the high risk score group, prevalence of clinically important alternative diagnosis was 1% (95% confidence interval 0%-2%) and 11% (95% confidence interval 8%-13%) of patients needed intervention. STONE scoring system is useful in estimating the prevalence of urolithiasis but high heterogeneity among the studies makes it unsuitable for application. Other decision tools were poorly studied and cannot be recommended for clinical use.

A New Simplified Biplanar (0-90°) Fluoroscopic Puncture Technique for Percutaneous Nephrolithotomy. Reducing Fluoroscopy Without Ultrasound. Initial Experience and Outcomes

ObjectiveTo present our simplified biplanar fluoroscopic puncture technique, its reduction in the fluoroscopic screening time as well as outcomes and the initial experience for percutaneous nephrolithotomy. MethodsWe performed a retrospective review of 136 patients operated with our simplified 0-90° puncture technique for percutaneous nephrolithotomy between 2015 and 2018. All patients were classified by stone complexity with Guy´s nephrolithometric stone score. The stone-free rate was evaluated by nonenhanced computerized tomography, and residual stones were defined as fragments ≥2 mm. Complications were divided according to the Clavien-Dindo classification. ResultsOne hundred and thirty-six patients were operated with our puncture technique; 121 patients were performed in supine and 15 in the prone position. Fifty-one were men, and 85 were women with an overall mean age of 44.36 ± 13.23 years. The overall stone-free rate was 62.5%, and 83.8 % after an ancillary procedure. The mean fluoroscopy screening time was 69.47 ± 7.1 and 6 ± 4.1 seconds for the total surgical procedure and the percutaneous puncture, respectively. Complications were present in 25.7%, and no grade IV and V complications were present. ConclusionOur first case series with the 0-90° simplified fluoroscopic puncture technique shows a similar stone-free rate and safety profile but a low fluoroscopic screening time compared to the most common previously reported fluoroscopic puncture techniques non-focused on low radiation protocols. Further studies are required to evaluate the reproducibility, external validation, and the learning curve of our simplified 0-90° technique.

Prediction of Surgical Outcome after Percutaneous Nephrolithotomy through Guy’s Score and Nephrolithometric Nomogram

Abstract Background Urolithiasis has a well documented common occurrence in the general population. Percutaneous nephrolithotomy (PCNL), has prevailed over other more morbid procedures, like open surgeries in the management of such stones PNL in complex renal stones is a challenging procedure because it requires considerable experience in gaining percutaneous tracts, performing delicate and judicious intrarenal manipulations, mastering all techniques of intracorporeal stone disintegration, and weighing the benefits of complete stone clearance against the risks of complications. Aim of the Work GSS and Nephrolithometric Nomogram. Scoring system in predicting PCNL outcomes. The ability of the GSS and STONE score to correlate with the post-operative change in the quality of life. Patients and Methods In a non-randomized prospective study we evaluated the two scoring systems Guy’s and S.T.O.N.E. nephrolithometry scoring systems in predicting the success rate of PCNl and the quality of life. This study included 100 patients with renal stones who were scheduled for PCNL at El Demerdash University Hospitals and Nasser institute hospital in the period from April 2017 to October 2018. Results Our study included 100 patients (34 were female, 66 were male) with a mean age of 46.16 (range from 28 to 68). The mean GUY score was 1.57± 0.73 and the mean STONE score was 5.76± 1.19.the overall stone free rate was 89% with a complication rate of 18% with a mean stone burden &amp;lt;400 mm.GUY and STONE score were able to predict SFR and complications after PCNL. Conclusion Both GSS and S.T.O.N.E Nephrolithometry Score can be used to stratify the complexity of renal stone before PCNL to predict the stone clearance and complication. Both can be valuable tools for providing uniformity for comparison of outcome, proper planning of the surgery and preoperative counseling of the patient.

Comparison of Stone Scoring Systems in Predicting Outcomes of Percutaneous Nephrolithotomy in Patients with Solitary Kidney

Comparison of Stone Scoring Systems in Predicting Outcomes of Percutaneous Nephrolithotomy in Patients with Solitary Kidney

Predicting the Postoperative Outcome of Percutaneous Nephrolithotomy with Machine Learning System: Software Validation and Comparative Analysis with Guy's Stone Score and the CROES Nomogram.

Purpose: To validate the output of a machine learning-based software as an intelligible interface for predicting multiple outcomes after percutaneous nephrolithotomy (PCNL). We compared the performance of this system with Guy's stone score (GSS) and the Clinical Research Office of Endourological Society (CROES) nomogram. Patients and Methods: Data from 146 adult patients (87 males, 59%) who underwent PCNL at our institute were used. To validate the system, accuracy of the software for predicting each postoperative outcome was compared with the actual outcome. Similarly, preoperative data were analyzed with GSS and CROES nomograms to determine stone-free status as predicted by these nomograms. A receiver operating characteristic (ROC) curve was generated for each scoring system, and the area under the ROC curve (AUC) was calculated and used to assess the predictive performance of all three models. Results: Overall stone-free rate was 72.6% (106/146). Forty of 146 patients (27.4%) were scheduled for 42 ancillary procedures (extracorporeal shockwave lithotripsy [SWL] [n = 31] or repeat PCNL [n = 11]) to manage residual renal stones. Overall, the machine learning system predicted the PCNL outcomes with an accuracy ranging between 80% and 95.1%. For predicting the stone-free status, the AUC for the software (0.915) was significantly larger than the AUC for GSS (0.615) or CROES nomograms (0.621) (p < 0.001). Conclusion: At the internal institutional level, the machine learning-based software was a promising tool for recording, processing, and predicting outcomes after PCNL. Validation of this system against an external dataset is highly recommended before its widespread application.