Event Abstract Back to Event Brain correlates of automatic stimulus-change detection in the visual modality: an fMRI study Helen Clery1*, P. Fonlupt2, N. Bruneau1 and M. Gomot1 1 CNRS FRE 2448, Université François Rabelais de Tours, CHRU de Tours, France 2 Inserm U821, Dynamique cérébrale et Cognition, Université Lyon I, France INTRODUCTION:Although the existence of an automatic detection of deviancy in the auditory system is recognized since several decades, the significance of its visual analog still contentious. Even if a number of studies support the presence of a visual MMN (vMMN), little is know about the brain generators involved in this processing. The present study was designed to localize the brain activations elicited by unattended visual deviant stimuli by fMRI. METHOD:Twelve healthy, right-handed adult volunteers participated in the study. The experiment consisted of an event-related fMRI paradigm in which stimuli consisted in the deformation of a circle into an ellipse either in the horizontal (standard) or in the vertical (deviant, p = 0,15) direction. In order to present the visual stimuli outside the focus of attention, a concurrent task was required in which subjects had to stare at the fixation cross and to respond to its random disappearance. RESULTS:Changes in BOLD response were evidenced bilaterally in different parts of the occipital cortex when deviant stimuli were presented to the subjects, but also in the superior parietal gyri and in the right frontal gyrus. CONCLUSION:This study allowed to evidence regional brain activity associated with passive detection of infrequently occurring visual deviant stimuli. Results showed activity in the modality-specific sensory cortex, but also in non specific areas involved in preattentional processing of changing events. Moreover these findings suggest the involvement of both the ventral and the dorsal visual pathway during such preattentive change-detection processing. Conference: MMN 09 Fifth Conference on Mismatch Negativity (MMN) and its Clinical and Scientific Applications, Budapest, Hungary, 4 Apr - 7 Apr, 2009. Presentation Type: Poster Presentation Topic: Poster Presentations Citation: Clery H, Fonlupt P, Bruneau N and Gomot M (2009). Brain correlates of automatic stimulus-change detection in the visual modality: an fMRI study. Conference Abstract: MMN 09 Fifth Conference on Mismatch Negativity (MMN) and its Clinical and Scientific Applications. doi: 10.3389/conf.neuro.09.2009.05.078 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 25 Mar 2009; Published Online: 25 Mar 2009. * Correspondence: Helen Clery, CNRS FRE 2448, Université François Rabelais de Tours, CHRU de Tours, Tours, France, helen.clery@inserm.fr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Helen Clery P. Fonlupt N. Bruneau M. Gomot Google Helen Clery P. Fonlupt N. Bruneau M. Gomot Google Scholar Helen Clery P. Fonlupt N. Bruneau M. Gomot PubMed Helen Clery P. Fonlupt N. Bruneau M. Gomot Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.