Stereoscopic Research Articles

Spatio-temporal dynamics of superstructures and vortices in turbulent Rayleigh–Bénard convection

Understanding turbulent thermal convection is essential for modeling many natural phenomena. This study investigates the spatiotemporal dynamics of the vortical structures in the mid-plane of turbulent Rayleigh–Bénard convection in SF6 via experiments. For this, a Rayleigh–Bénard cell of aspect ratio 10 is placed inside a pressure vessel and pressurized up to 1, 1.5, and 2.5 bar in order to reach Rayleigh numbers of Ra = 9.4×105,2.0×106, and 5.5×106, respectively. For all three cases, the Prandtl number is Pr =0.79 and ΔT≈7 K. Then, stereoscopic particle image velocimetry is conducted to measure the three velocity components in the horizontal-mid-plane for 5.78×103 free fall times. For the given aspect ratio, the flow is no longer dominated by the side walls of the cell and turbulent superstructures that show a two-dimensional repetitive organization form. These superstructures show diverse shapes with faster dissipation rates as Ra increases. Out-of-plane vortices are the main feature of the flow. As Ra increases, the number of these vortices also increases, and their size shrinks. However, their total number is almost constant for each Ra through the measurement period. Furthermore, their occurrence is random and does not depend on whether the flow is upward-heated, downward-cooled, or horizontally directed. Vortex tracking was applied to measure lifetime, displacement, and traveled distance of these structures. The relation between lifetime and traveled distance is rather linear. Interestingly, in the vortex centers, the out-of-plane momentum transport is larger in comparison to the bulk flow. Therefore, these vortices will play a major role in the heat transport in such flows.

Combining visual interpretation and image segmentation to derive canopy cover index from high resolution satellite imagery in functionally diverse coniferous forests

Forest canopy cover is one of the most significant structural parameters of the forest stand that can be estimated using of aerial and satellite remote sensing. Even though sub-pixel analysis can be used to estimate the index on low-resolution imagery, high-resolution imagery provides more accurate details on forest canopy variability for ecological and forestry applications. However, the high variability of the images demands a more advanced approach to canopy cover measurement than the visual interpretation of single images or stereo pairs. These traditional methods are inefficient and limited in providing a comprehensive and accurate canopy cover assessment. An improvement of the method could involve classifying high spatial resolution images, separating and extracting the areas corresponding to canopy gaps, and generating canopy cover maps. This study offers valuable insights and reveals key differences between three methods for estimating canopy cover: ground measurements, visual photo interpretation and automatic extraction from classified images using pixel and object-based methods. The texture analysis approach was used for separating the “shadow” objects corresponding to gaps in the canopy from the shades cast on the lower trees. The sample plot-based visual interpretation of the images revealed comparable results between ground and satellite image canopy cover values (correlation coefficient of 0.74 for all plots), with lower correlations (r = 0.39) for uneven-aged stands. The results encourage the use of the texture analysis method, with satisfying accuracy (forest canopy cover differences of maximum 0.06 between ground, photo interpreted and extracted datasets). The method could be further integrated with complementary data like LIDAR or hyperspectral images.

Performance of the Thies Clima 3D Stereo Disdrometer: Evaluation during Rain and Snow Events.

Imaging disdrometers are widely used in field campaigns to provide information on the shape of hydrometeors, together with the diameter and the fall velocity, which can be used to derive information on the shape-size relations of hydrometeors. However, due to their higher price compared to laser disdrometers, their use is limited to scientific research purposes. The 3D stereo (3DS) is a commercial imaging disdrometer recently made available by Thies Clima and on which there are currently no scientific studies in the literature. The most innovative feature of the 3DS is its ability in capturing images of the particles passing through the measurement volume, crucial to provide an accurate classification of hydrometeors based on information about their shape, especially in the case of solid precipitation. In this paper. the performance of the new device is analyzed by comparing 3DS with the Laser Precipitation Monitor (LPM) from the same manufacturer, which is a known laser disdrometer used in many research works. The data used in this paper were obtained from measurements of the two instruments carried out at the Casale Calore site in L'Aquila during the CORE-LAQ (Combined Observations of Radar Experiments in L'Aquila) campaign. The objective of the comparison analysis is to analyze the differences between the two disdrometers in terms of hydrometeor classification, number and falling speed of particles, precipitation intensity, and total cumulative precipitation on an event basis. As regards the classification of precipitation, the two instruments are in excellent agreement in identifying rain and snow; greater differences are observed in the case of particles in mixed phase (rain and snow) or frozen phase (hail). Due to the different measurement area of the two disdrometers, the 3DS generally detects more particles than the LPM. The performance differences also depend on the size of the hydrometeors and are more significant in the case of small particles, i.e., D < 1 mm. In the case of rain events, the two instruments are in agreement with respect to the terminal velocity in still air predicted by the Gunn and Kinzer model for drops with a diameter of less than 3 mm, while, for larger particles, terminal velocity is underestimated by both the disdrometers. The agreement between the two instruments in terms of total cumulative precipitation per event is very good. Regarding the 3DS ability to capture images of hydrometeors, the raw data provide, each minute, from one to four images of single particles and information on their size and type. Their number and coarse resolution make them suitable to support only qualitative analysis of the shape of precipitating particles.

An Epigenome-Wide Association Study of DNA Methylation and Proliferative Retinopathy over 28 Years in Type 1 Diabetes

To perform a prospective epigenome-wide association study of DNA methylation (DNAm) and 28-year proliferative diabetic retinopathy (PDR) incidence in type 1 diabetes (T1D). Prospective observational cohort study. The Pittsburgh Epidemiology of Diabetes Complications (EDC) study of childhood-onset (< 17 years) T1D. Stereoscopic fundus photographs were taken in fields 1, 2, and 4 at baseline, 2, 4, 6, 8, 16, 23, and 28 years after DNAm measurements. The photos were graded using the modified Airlie House System. In those free of PDR at baseline (n=265; mean T1D duration of 18 years at baseline), whole blood DNAm (EPIC array) at 683 597 CpGs was analyzed in Cox models for time to event. Associations between significant CpGs and clinical risk factors were assessed; genetic variants associated with DNAm were identified (methylation quantitative trait loci [meQTLs]). Mendelian randomization was used to examine evidence of causal associations between DNAm and PDR. Post hoc regional and functional analyses were performed. Proliferative diabetic retinopathy was defined as the first instance of a grade of ≥ 60 in at least 1 eye or pan-retinal photocoagulation for PDR. Follow-up time was calculated from the study visit at which DNAm data were available (baseline) until PDR incidence or censoring (December 31, 2018 or last follow-up). PDR incidence was 53% over 28-years' follow-up. Greater DNAm of cg27512687 (KIF16B) was associated with reduced PDR incidence (P=6.3×10-9; false discovery rate [FDR]: < 0.01); 113 cis-meQTLs (P<5×10-8) were identified. Mendelianrandomization analysis using the sentinel meQTL as the instrumental variable supported a potentially causal association between cg27512687 and PDR. Cg27512687 was also associated with lower pulse rate and albumin excretion rate and higher estimated glomerular filtration rate, but its association with PDR remained independently significant after adjustment for those factors. In regional analyses, DNAm of FUT4, FKBP1A, and RIN2 was also associated with PDR incidence. DNA methylation of KIF16B, FUT4, FKBP1A, and RIN2 was associated with PDR incidence, supporting roles for epigenetic regulation of iron clearance, developmental pathways, and autophagy in PDR pathogenesis. Further study of those loci may provide insight into novel targets for interventions to prevent or delay PDR in T1D. Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Tip Vortex Study of a Rotor with Double-Swept Blade Tips

An experimental aerodynamic study was conducted, analyzing the wake structure of a four-bladed model rotor with a forward-backward swept tip geometry inspired by the ONERA-DLR “Etude d´un Rotor Aéroacoustique Technologiquement Optimisé”-design. Similar tip designs are used on some modern helicopter main rotors. The experiments were conducted at the Rotor Test Facility Göttingen (RTG) in hover-like conditions using a stereoscopic high-speed particle image velocimetry system. The results are compared with those of a reference rotor using a conventional parabolic blade tip. The test parameters include both constant-pitch cases and pitch-oscillating cases with a cyclic swashplate input. The constant-pitch tests show a two-step stall behavior for the double-swept tip, with the first step characterized by a reduced thrust slope and a reduced rotor efficiency. This effect is explained by a repositioning and a structural change of the tip vortex generation. The pitch-oscillating cases show that the double-swept tip results in an earlier tip stall compared to the parabolic geometry while maintaining high thrust levels. The dynamic tip stall yields a break-down of the wake’s tip vortex system, which is replaced by a spanwise band with small-scale turbulent structures and trailed vorticity, but no large-scale vortices.

Impact of focus cue presentation on perceived realism of 3-D scene structure: Implications for scene perception and for display technology.

Stereoscopic imagery often aims to evoke three-dimensional (3-D) percepts that are accurate and realistic-looking. The "gap" between 3-D imagery and real scenes is small, but focus cues typically remain incorrect because images are displayed on a single focal plane. Research has concentrated on the resulting vergence-accommodation conflicts. Yet, incorrect focus cues may also affect the appearance of 3-D imagery. We investigated whether incorrect focus cues reduce perceived realism of 3-D structure ("depth realism"). Experiment1 used a multiple-focal-planes display to compare depth realism with correct focus cues vs. conventional stereo presentation. The stimuli were random-dot stereograms, which isolated the role of focus cues. Depth realism was consistently lower with incorrect focus cues, providing proof-of-principle evidence that they contribute to perceptual realism. Experiments2 and3 examined whether focus cues play a similar role with realistic objects, presented with an almost complete set of visual cues using a high-resolution, high-dynamic-range multiple-focal-planes display. We also examined the efficacy of approximating correct focus cues via gaze-contingent depth-of-field rendering. Improvements in depth realism with correct focus cues were less clear in more realistic scenes, indicating that the role of focus cues in depth realism depends on scene content. Rendering-based approaches, if anything, reduced depth realism, which we attribute to their inability to present higher-order aspects of blur correctly. Our findings suggest future general 3-D display solutions may need to present focus cues correctly to maximise perceptual realism.

Light Field Visualization for Training and Education: A Review

Three-dimensional visualization technologies such as stereoscopic 3D, virtual reality, and augmented reality have already emerged in training and education; however, light field displays are yet to be introduced in such contexts. In this paper, we characterize light field visualization as a potential candidate for the future of training and education, and compare it to other state-of-the-art 3D technologies. We separately address preschool and elementary school education, middle and high school education, higher education, and specialized training, and assess the suitability of light field displays for these utilization contexts via key performance indicators. This paper exhibits various examples for education, and highlights the differences in terms of display requirements and characteristics. Additionally, our contribution analyzes the scientific-literature-related trends of the past 20 years for 3D technologies, and the past 5 years for the level of education. While the acquired data indicates that light field is still lacking in the context of education, general research on the visualization technology is steadily rising. Finally, we specify a number of future research directions that shall contribute to the emergence of light field visualization for training and education.

A comprehensive review of image retargeting

With the development of display technologies, image retargeting plays a significant role in computer vision and pattern recognition communities currently. Image retargeting aims to display an image on a series of appliances with different resolutions and target aspect ratios. During the last decade, representative algorithms for image retargeting have been presented in the literature and achieved state-of-the-art performance. In this survey, we provide a comprehensive review of image retargeting, covering a wide variety of pioneering works for 2D image retargeting and stereoscopic image retargeting. 2D image retargeting focuses on preserving interesting regions when modifying the original image with arbitrary resolutions appropriately. Different from 2D image retargeting, stereoscopic image retargeting needs to preserve both the shape structure of salient objects and the depth consistency of 3D scenes simultaneously. In this survey, we start the first attempt to analyze the trends of 2D image retargeting and then summarize different types of stereoscopic image retargeting. Secondly, image retargeting quality assessment metrics for 2D images and stereoscopic images are introduced to evaluate retargeted images. Thirdly, we also investigate the evaluation datasets, and give the comparison results and analysis between different representative methods. Finally, the promising future research is thoroughly discussed to further improve the performance of 2D and stereoscopic image retargeting.

Effect of Freeze–Thaw Cycles on Microstructure and Hydraulic Characteristics of Claystone: A Case Study of Slope Stability from Open-Pit Mines in Wet Regions

The action of freeze–thaw (F–T) cycles of claystone exerts a profound impact on the slope stability of open-pit mines in water-rich regions. Microstructural changes are observed as a crucial factor in determining the hydraulic characteristics and mechanical behaviors of claystone. The present work integrates a micro-X-ray computed tomography (Micro-CT) scanner, equipped with image processing and three-dimensional (3D) reconstruction capabilities, employed to observe the microstructure of claystone under varying numbers of F–T cycles (0, 10, 20, 30, and 50). Furthermore, seepage numerical simulations based on Micro-CT measurements are conducted to evaluate the hydraulic characteristics. Through meticulous microscopic observation and mechanical analysis, the damage mechanism induced by F–T cycles is revealed and the evolutionary characteristics are analyzed. The two-dimensional (2D) images of 3D reconstructed models unveil the gradual initiation propagation and coalescence of an intricate fissuring network in claystone during the F–T cycles. As the number of F–T cycles increases from 0 to 50, the 3D porosity exhibits exponential growth. Additionally, the influence of F–T cycles substantially enhances the connectivity of fissures. The seepage numerical simulations demonstrate that the evolutionary progression of fissures substantially augments the number of flow paths and enhances permeability. The increase in permeability follows an exponential trend, reflecting the distribution and evolution of fissures under F–T cycles. The impact on permeability arises from a combination of micromechanical properties and the microstructure of claystones. The present research tries to elucidate the microscopic evolution of fissures and their corresponding hydraulic properties in water-saturated claystone, offering significant insights for investigating the slope stability of open-pit mines in regions.

Educational stereoscopic representation of a step-by-step brain white fiber dissection according to Klingler's method.

Understanding and teaching the three-dimensional architecture of the brain remains difficult because of the intricate arrangement of grey nuclei within white matter tracts. Although cortical area functions have been well studied, educational and three-dimensional descriptions of the organization of deep nuclei and white matter tracts are still missing. We propose herein a detailed step-by-step dissection of the lateral aspect of a left hemisphere using the Klingler method and provide high-quality stereoscopic views with the aim to help teach medical students or surgeons the three-dimensional anatomy of the brain. Three left hemispheres were extracted and prepared. Then, according to the Klingler method, dissections were carried out from the lateral aspect. Photographs were taken at each step and were modified to provide stereoscopic three-dimensional views. Gray and white structures were described: cortex, claustrum, putamen, pallidum, caudate nucleus, amygdala; U-fibers, external and internal capsules, superior longitudinal fasciculus, frontal aslant fasciculus, uncinate fasciculus, inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, corticospinal fasciculus, corona radiata, anterior commissure, and optic radiations. This educational stereoscopic presentation of an expert dissection of brain white fibers and basal ganglia would be of value for theoretical or hands-on teaching of brain anatomy; labeling and stereoscopy could, moreover, improve the teaching, understanding, and memorizing of brain anatomy. In addition, this could be also used for the creation of a mental map by neurosurgeons for the preoperative planning of brain tumorsurgery.

Generation of a Digital Terrain Model (DTM) Fusioning WV-2 Images and RTK-derived Topobathymetric Data

Digital terrain models (DTMs) are digital elevation models (DEMs) that represent the bare ground surface. They are created by multiple sources, including satellite remote sensing, aerial photography, and ground-based surveys, and are often combined with other data sources to create highly detailed models. As the demand for accurate and detailed information about the Earth's surface continues to grow, DTMs have become an increasingly important tool for researchers in different fields. This study aims to create a DTM with a spatial resolution of 0.50 m for São Caetano do Sul, São Paulo, Brazil, integrated with a topobathymetric map of three water courses running along the borders of the study area. For the conventional DTM generation, a WV-2 stereo pair was used. A total of 55 ground control points (GCPs) were collected using the GNSS-RTK method, being 60% used for model building and 40% employed for validation. The topobathymetric survey was accomplished using a GNSS-RTK device placed along the analyzed open streams. For validation purposes, we used bias and MAE metrics. Overall, the methodology presented in this article provides a useful approach for generating high-resolution DTMs that can be used in a range of applications, especially in urban hydrodynamic studies.

Stereo Visual Servoing Control of a Soft Endoscope for Upper Gastrointestinal Endoscopic Submucosal Dissection.

Quickly and accurately completing endoscopic submucosal dissection (ESD) operations within narrow lumens is currently challenging because of the environment's high flexibility, invisible collision, and natural tissue motion. This paper proposes a novel stereo visual servoing control for a dual-segment robotic endoscope (DSRE) for ESD surgery. Departing from conventional monocular-based methods, our DSRE leverages stereoscopic imaging to rapidly extract precise depth data, enabling quicker controller convergence and enhanced surgical accuracy. The system's dual-segment configuration enables agile maneuverability around lesions, while its compliant structure ensures adaptability within the surgical environment. The implemented stereo visual servo controller uses image features for real-time feedback and dynamically updates gain coefficients, facilitating rapid convergence to the target. In visual servoing experiments, the controller demonstrated strong performance across various tasks. Even when subjected to unknown external forces, the controller maintained robust performance in target tracking. The feasibility and effectiveness of the DSRE were further verified through ex vivo experiments. We posit that this novel system holds significant potential for clinical application in ESD surgeries.

Association between visceral fat area and diabetic retinopathy among people with type 2 diabetes mellitus: a cross-sectional study in Ningbo, Zhejiang Province, China.

The objective of this study is to investigate the relationship between visceral fat area (VFA) and diabetic retinopathy (DR) in the context of type 2 diabetes mellitus (T2DM) within Ningbo, China. The data of a total of 3,707 subjects with T2DM treated at The First Affiliated Hospital of Ningbo University were enrolled. The existence and severity of diabetic retinopathy were assessed by employing the 45° two-field stereoscopic digital photography. Subjects were categorized into four distinct groups: those without DR (NDR), individuals with mild non-proliferative DR (mild NPDR), people with moderate non-proliferative DR (moderate NPDR), and those suffering from vision-threatening DR (VTDR). Bio-electrical impedance was employed to estimate the Visceral fat area (VFA). Multinomial logistic regression models were utilized to evaluate the association between VFA and DR. The mean VFA in patients without diabetic retinopathy (NDR) was notably lower compared to that of patients with diabetic retinopathy (DR) (85.21 ± 37.78 vs. 97.37 ± 44.58 cm2, p < 0.001). As the severity of DR increased, VFA increased gradually but insignificantly (94.41 ± 43.13 cm2, 96.75 ± 40.82 cm2, 100.84 ± 49.34 cm2, p = 0.294). After adjusting the confounding factors, there was an association identified between VFA and the occurrence of DR (OR = 1.020, 95% CI = 1.016-1.024). It showed that regardless of BMI, whether it's less than 25 kg/m2 or greater than or equal to 25 kg/m2, a higher VFA (≥100 cm2) level came with a higher prevalence of DR (p < 0.001). The outcomes of this research indicate a modest association between VFA and the incidence of DR among Chinese patients who have been diagnosed with T2DM in Ningbo.

Measurement of Three‐Dimensional Bubble distributionVia Single‐Directional Capture Using a Light Field Camera

In water electrolysis, which converts electricity into hydrogen, the distribution of bubbles affects ion transport in the electrolyte. Therefore, measuring the three‐dimensional distribution of bubbles in the electrolysis cell can be effective in improving efficiency. However, the electrolysis cell contains electrodes and membranes, making it difficult to use conventional stereo photography to measure the three‐dimensional bubble distribution. Therefore, in this study, we investigated the measurement of the three‐dimensional distribution of bubbles in liquids using a light field camera that enables three‐dimensional imaging from one direction by using a microlens array. The study was conducted by performing imaging experiments of bubbles ejected from an axisymmetric nozzle using a light field camera and determining whether the measurement of the three‐dimensional distribution of bubbles was possible. As a result, we found that the axisymmetric bubble distribution can be measured in three dimensions and that a light field camera can be used for this measurement. © 2024 Institute of Electrical Engineer of Japan and Wiley Periodicals LLC.

Octonion-based transform moments for innovative stereo image classification with deep learning

Recent advances in imaging technologies have led to a significant increase in the adoption of stereoscopic images. However, despite this proliferation, in-depth research into the complex analysis of the visual content of these stereoscopic images is still relatively rare. The advent of stereoscopic imaging has brought a new dimension to visual content. These images offer a higher level of visual detail, making them increasingly common in a variety of fields, including medicine and industrial applications. However, exploiting the full potential of stereoscopic images requires a deeper understanding. By exploiting the capabilities of octonion moments and the power of artificial intelligence, we aim to break new ground by introducing a novel method for classifying stereoscopic images. The proposed method is divided into two key stages: The first stage involves data preprocessing, during which we strive to construct a balanced database divided into three distinct categories. In addition, we extract the stable Octonion Krawtchouk moments (SOKM) for each image, leading to a database of moment images with dimensions of 128 × 128 × 1. In the second step, we train a convolutional neural network (CNN) model using this database, with the aim of discriminating between different categories. Standard measures such as precision, accuracy, recall, F1 score, and ROC curves are used to assess the effectiveness of our method. These measures provide a quantitative assessment of the performance of our object classification approach for stereoscopic images.

Paintings in naked-eye virtual reality: a parallax view between the surface and volumetric depth

This article explores a subgenre of naked-eye virtual reality (VR) video that features two-dimensional paintings in a three-dimensional space and is circulated on the Chinese video streaming website Bilibili. In contrast to traditional VR, which requires the spectator to wear a head-mounted display, naked-eye VR offers a stereoscopic view on the screen, eliminating the need for VR glasses. The apparent incongruity between the screen’s physical flatness and the volumetric depth of the painting becomes even more pronounced when the naked-eye VR image emphasises the painting’s inherent two-dimensionality. Employing an interdisciplinary humanities’ method that connects media archaeology, film studies, art history, and the field of science, technology, and society, this paper delves into this distinctive juxtaposition between the painting’s flatness and the volumetric depth characteristic of naked-eye VR, a subgenre that remains mostly uncharted in the field of film and media studies. Taking a media archaeological perspective, this paper introduces a parallax media history, suggesting that the aesthetics of VR can be traced not only to the stereoscope but also to scroll paintings, which are paradoxically defined by their flat compositions. In addition, naked-eye VR references pictorial traditions by generating a spatial illusion that leads spectators to feel as if they are delving beneath the surface of a painting, transitioning from spatial extensivity on the x-y axis to perceived depth along the z-axis. This oscillation between surface and depth is engendered by the horizontal parallax rooted in binocular disparity, thereby positioning naked-eye VR as a “parallax media.” In analysing the illusion created by naked-eye VR, this paper proposes a paradigmatic shift in the framework of media study from conceiving of an image as a mirror to experiencing it as a door, representing the oscillation between volumetric depth and two-dimensional surface.

Multi-View Jujube Tree Trunks Stereo Reconstruction Based on UAV Remote Sensing Imaging Acquisition System

High-quality agricultural multi-view stereo reconstruction technology is the key to precision and informatization in agriculture. Multi-view stereo reconstruction methods are an important part of 3D vision technology. In the multi-view stereo 3D reconstruction method based on deep learning, the effect of feature extraction directly affects the accuracy of reconstruction. Aiming at the actual problems in orchard fruit tree reconstruction, this paper designs an improved multi-view stereo structure based on the combination of remote sensing and artificial intelligence to realize the accurate reconstruction of jujube tree trunks. Firstly, an automatic key frame extraction method is proposed for the DSST target tracking algorithm to quickly recognize and extract high-quality data. Secondly, a composite U-Net feature extraction network is designed to enhance the reconstruction accuracy, while the DRE-Net feature extraction enhancement network improved by the parallel self-attention mechanism enhances the reconstruction completeness. Comparison tests show different levels of improvement on the Technical University of Denmark (DTU) dataset compared to other deep learning-based methods. Ablation test on the self-constructed dataset, the MVSNet + Co U-Net + DRE-Net_SA method proposed in this paper improves 20.4% in Accuracy, 12.8% in Completion, and 16.8% in Overall compared to the base model, which verifies the real effectiveness of the scheme.

Association of Visceral Obesity Indices With Incident Diabetic Retinopathy in Patients With Diabetes: Prospective Cohort Study.

Visceral adipose tissue plays an active role in the pathogenesis of type 2 diabetes and vascular dysfunction. The lipid accumulation product (LAP), visceral adiposity index (VAI), and Chinese VAI (CVAI) have been proposed as simple and validated surrogate indices for measuring visceral adipose tissue. However, the evidence from prospective studies on the associations between these novel indices of visceral obesity and diabetic retinopathy (DR) remains scant. This study aimed to investigate the longitudinal associations of LAP, VAI, and CVAI with incident DR in Chinese patients with diabetes. This was a prospective cohort study conducted in Guangzhou in southern China. We collected baseline data between November 2017 and July 2020, while on-site follow-up visits were conducted annually until January 2022. The study participants consisted of 1403 patients with a clinical diagnosis of diabetes, referred from primary care, who were free of DR at baseline. The LAP, VAI, and CVAI levels were calculated by sex-specific equations based on anthropometric and biochemical parameters. DR was assessed using 7-field color stereoscopic fundus photographs and graded according to the modified Airlie House Classification scheme. Time-dependent Cox proportional hazard models were constructed to estimate the hazard ratios with 95% CIs. Restricted cubic spline curves were fitted to examine the dose-response relationship between the 3 indices of visceral obesity and new-onset DR. Subgroup analyses were performed to investigate the potential effect modifiers. The mean age of study participants was 64.5 (SD 7.6) years, and over half (816/1403, 58.2%) were female. During a median follow-up of 2.13 years, 406 DR events were observed. A 1-SD increment in LAP, VAI, or CVAI was consistently associated with increased risk for new-onset DR, with a multivariable‑adjusted hazard ratio of 1.24 (95% CI 1.09-1.41; P=.001), 1.22 (95% CI 1.09-1.36; P<.001), and 1.48 (95% CI 1.19-1.85; P=.001), respectively. Similar patterns were observed across tertiles in LAP (P for trend=.001), VAI (P for trend<.001), and CVAI (P for trend=.009). Patients in the highest tertile of LAP, VAI, and CVAI had an 84%, 86%, and 82% higher hazard of DR, respectively, compared to those in the lowest tertile. A nonlinear dose-response relationship with incident DR was noted for LAP and VAI (both P for nonlinearity<.05), but not for CVAI (P for nonlinearity=.51). We did not detect the presence of effect modification by age, sex, duration of diabetes, BMI, or comorbidity (all P for interaction>.10). Visceral obesity, as measured by LAP, VAI, or CVAI, is independently associated with increased risk for new-onset DR in Chinese patients with diabetes. Our findings may suggest the necessity of incorporating regular monitoring of visceral obesity indices into routine clinical practice to enhance population-based prevention for DR.

New Type Annihilator of π-Expanded Diketopyrrolopyrrole for Robust Photostable NIR-Excitable Triplet-Triplet Annihilation Upconversion.

Near-infrared light excitable triplet-triplet annihilation upconversion (NIR TTA-UC) materials have attracted interest in a variety of emerging applications such as photoredox catalysis, optogenetics, and stereoscopic 3D printing. Currently, the practical application of NIR TTA-UC materials requires substantial improvement in photostability. Here, we found that the new annihilator of π-expanded diketopyrrolopyrrole (π-DPP) cannot activate oxygen to generate superoxide anion via photoinduced electron transfer, and its electron-deficient characteristics prevent the singlet oxygen-mediated [2 + 2] cycloaddition reaction; thus, π-DPP exhibited superior resistance to photobleaching. In conjunction with the NIR photosensitizer PdTNP, the upconversion efficiency of π-DPP is as high as 8.9%, which is eight times of the previously reported PdPc/Furan-DPP. Importantly, after polystyrene film encapsulation, less than 10% photobleaching was observed for this PdTNP/π-DPP-based NIR TTA-UC material after four hours of intensive NIR light exposure. These findings provide a type of annihilator with extraordinary photostability, facilitating the development of NIR TTA-UC materials for practical photonics.

Spatial perception in stereoscopic augmented reality based on multifocus sensing

In many areas ranging from medical imaging to visual entertainment, 3D information acquisition and display is a key task. In this regard, in multifocus computational imaging, stacks of images of a certain 3D scene are acquired under different focus configurations and are later combined by means of post-capture algorithms based on image formation model in order to synthesize images with novel viewpoints of the scene. Stereoscopic augmented reality devices, through which is possible to simultaneously visualize the three dimensional real world along with overlaid digital stereoscopic image pair, could benefit from the binocular content allowed by multifocus computational imaging. Spatial perception of the displayed stereo pairs can be controlled by synthesizing the desired point of view of each image of the stereo-pair along with their parallax setting. The proposed method has the potential to alleviate the accommodation-convergence conflict and make augmented reality stereoscopic devices less vulnerable to visual fatigue.