A three-dimensional (3D) video is a special video representation with an artificial stereoscopic vision effect that increases the depth perception of the viewers. The quality of a 3D video is generally measured based on the similarity to stereoscopic vision obtained with the human vision system (HVS). The reason for the usage of these high-cost and time-consuming subjective tests is due to the lack of an objective video Quality of Experience (QoE) evaluation method that models the HVS. In this paper, we propose a hybrid 3D-video QoE evaluation method based on spatial resolution associated with depth cues (i.e., motion information, blurriness, retinal-image size, and convergence). The proposed method successfully models the HVS by considering the 3D video parameters that directly affect depth perception, which is the most important element of stereoscopic vision. Experimental results show that the measurement of the 3D-video QoE by the proposed hybrid method outperforms the widely used existing methods. It is also found that the proposed method has a high correlation with the HVS. Consequently, the results suggest that the proposed hybrid method can be conveniently utilized for the 3D-video QoE evaluation, especially in real-time applications.