BackgroundRestoring medial knee pivot kinematics post-total knee arthroplasty is widely recognized to enhance patient satisfaction. Our study investigates the kinematics of patients who received posterior stabilized implants via robotic-arm assisted surgery, specifically analyzing effects of implant alignment and soft tissue balance on pivot location. MethodsTwelve high-functioning patients with unilateral posterior stabilizing knee implants underwent CT-guided robotic-arm assisted surgery. We then evaluated their knee kinematics using stereo radiography during gait, stair descent, lunge, seated knee extension and leg press. Femoral low-point condylar kinematics were used to calculate the transverse center of rotation, or pivot, using principal component analysis. Linear mixed effects regression was used to identify surgical parameters that influence pivot location across a flexion range. FindingsAcross all five activities a central pivot pattern emerged as the primary pivot location (40 %) followed by medial (25 %), no pivot (22 %) and lateral (14 %). Tibial medial resection depth and Tibial implant flexion-extension placement were significantly associated with shifting the pivot location laterally prior to cam-post engagement. Femoral implant external-internal implant placement, and medial compartment laxity in extension were significantly associated with shifting the pivot location laterally during the cam-post engagement, while femoral distal-lateral resection depth was associated with a medial shift. InterpretationCentral and medial pivot locations are predominant in patients with posterior stabilized total knee arthroplasty, facilitated by robotic-arm assisted surgery. Despite significant associations between surgical parameters such as tibial medial resection depth and lateral compartment laxity with medial pivot, these variables explained a small portion of the variability in pivot location. This suggests that while surgical precision influences pivot kinematics, individual patient factors may play a more critical role, suggesting a need for further research into patient-specific biomechanics to optimize post-surgical outcomes.