Stem-cement Interface Research Articles

The influence of proximal stem geometry and surface finish on the fixation of a double-tapered cemented femoral stem

In this study, the in vitro fixation of four otherwise identical double-tapered stem-types, varying only in surface finish (polished or matte) and proximal stem geometry (with or without flanges) were compared under two conditions. First, four specimens of each stem type were tested with initially bonded stem–cement interfaces, representing early post-operative conditions. Then, simulating conditions a few weeks to months later, stems were implanted in unused synthetic femurs, with a thin layer coating the stem to prevent stem–cement adhesion. Per-cycle motions were measured at both cement interfaces throughout loading. Overall, surface finish had the smallest relative effect on fixation compared to flanges. Flanges increased axial fixation by 22 μm per-cycle, regardless of surface finish ( P=0.01). Further, all stems moved under dynamic load at the stem–cement interface during the first few cycles of loading, even without a thin film. The results indicate that flanges have a greater effect on fixation than surface finish, and therefore adverse findings about matte surfaces should not necessarily apply to all double-tapered stems. Specifically, dorsal flanges enhance the stability of a tapered cemented femoral stem, regardless of surface finish.

Functional interface micromechanics of 11 en-bloc retrieved cemented femoral hip replacements

Background and purpose Despite the longstanding use of micromotion as a measure of implant stability, direct measurement of the micromechanics of implant/bone interfaces from en bloc human retrievals has not been performed. The purpose of this study was to determine the stem-cement and cement-bone micromechanics of functionally loaded, en-bloc retrieved, cemented femoral hip components.Methods 11 fresh frozen proximal femurs with cemented implants were retrieved at autopsy. Specimens were sectioned transversely into 10-mm slabs and fixed to a loading device where functional torsional loads were applied to the stem. A digital image correlation technique was used to document micromotions at stem-cement and cement-bone interfaces during loading.Results There was a wide range of responses with stem-cement micromotions ranging from 0.0006 mm to 0.83 mm (mean 0.17 mm, SD 0.29) and cement-bone micromotions ranging from 0.0022 mm to 0.73 mm (mean 0.092 mm, SD 0.22). There was a strong (linear-log) inverse correlation between apposition fraction and micromotion at the stem-cement interface (r2 = 0.71, p < 0.001). There was a strong inverse log-log correlation between apposition fraction at the cement-bone interface and micromotion (r2 = 0.85, p < 0.001). Components that were radiographically well-fixed had a relatively narrow range of micromotions at the stem-cement (0.0006–0.057 mm) and cement-bone (0.0022–0.029 mm) interfaces.Interpretatation Minimizing gaps at the stem-cement interface and encouraging bony apposition at the cement-bone interface would be clinically desirable. The cement-bone interface does not act as a bonded interface in actual use, even in radiographically well-fixed components. Rather, the interface is quite compliant, with sliding and opening motions between the cement and bone surfaces.

Femoral Stem Displacement During Closed Reduction of a Dislocated Bipolar Hemiarthroplasty of the Hip

This article describes a case of femoral stem displacement during closed reduction of a redislocated bipolar hemiarthroplasty of the hip in a 72-year-old woman who had undergone bipolar hemiarthroplasty using a polished, tapered cemented femoral stem. The polished, tapered cemented femoral stem is vulnerable to displacement when exposed to traction forces. Six days after bipolar hemiarthroplasty, the patient experienced her first dislocation, and immediate reduction of the dislocated hip was easily achieved. However, on the ninth postoperative day, redislocation occurred, and this time, reduction was not achieved. Subsequent radiographs revealed an unreduced state with posterosuperior dislocation of the hip and dissociation of the femoral stem at the cement-stem interface with proximal migration. Open reduction was then performed, and it was noted that the bipolar prosthesis had dislocated posterosuperiorly, the neck of the femoral stem was incarcerated between the short external rotators, and the femoral stem had migrated proximally by approximately 8 cm. The femoral stem was repositioned by freeing it from the short external rotators and gently tapping it into the cement mantle. Our surgical solution is questionable, because the stability of the stem is likely to be inadequate. According to the established study, no difference in stuffiness was observed before extraction and after reinsertion, which supports the surgical solution we chose. Pre-reduction analysis should be conducted to determine the cause and status of a dislocation, and open reduction should be performed if closed reduction fails when treating dislocated bipolar hemiarthroplasty patients.

Random damage and characteristics of debris particles are two important and yet ignored factors in the mechanical integrity of the stem-cement interface of a total hip replacement: influence of the surface finish of the metal stem

The importance of the conditions at the stem-cement interface in cemented total joint replacements (THRs) with regard to the in vivo longevity of the implant is well recognized. In the present study, we used a simplified model of one part of a cemented THR (alloy rectangular beam bonded to rectangular cement plate) to study the influence of surface finish of the alloy beam (stem) on two measures of the evolution of random damage at the alloy beam-cement plate interface (stem-cement interface), under quasi-static direct shear load. Three surface finishes of the beams were used: satin-finish, grit-blasted, and plasma-sprayed. The random damage events were monitored from the emitted acoustic signals, with the two measures computed from these signals being the intensity of random damage events (IRDE) and the mean damage event energy (MDEE). Large number of random damage events (higher values of IRDE and low value of MDEE) occurred with grit blasted specimens, suggesting a high probability for the generation of debris particles at the interface. These findings, in conjunction with details on the size and shape of the debris particles, obtained using scanning electron microscopy, lead to the suggestion that satin-finish stems are desirable for use in cemented THRs.

Nondestructive evaluation of bone cement and bone cement/metal interface failure

To quantify the failure mechanisms related to the loosening of cemented hip joint replacements, novel techniques, capable of monitoring, nondestructively, the initiation and progression of failure during in vitro fatigue tests, were employed. Fatigue testing of model cement and cement-stem test pieces was monitored using acoustic emission (AE) sensors. Once damage was detected, an ultrasonic imaging system was used to obtain an image of the damage site and to measure the stiffness of the affected region. This method of examination provided a detailed insight into the internal crack propagation and delamination patterns. Initial work was conducted on bulk cement specimens subjected to bending and tension. The second stage of the work examined a model stem-cement interface under tensile opening loading conditions. A novel ultrasonic technique was used to measure the bond quality at the cement-metal interface. Progressive delamination was identified over time, and the AE technique was able to identify critical areas of delamination before they could be identified conclusively by ultrasonic imaging. The work has demonstrated the potential of the AE technique as a tool for the preclinical assessment of total hip replacements.

Investigation of relative micromotion at the stem—cement interface in total hip replacement

Cemented total hip replacement has become a standard surgical technique to treat patients with osteoarthritis and osteonecrosis. The stem-cement interface experiences fretting wear in vivo due to low-amplitude oscillatory micromotion under physiological loading, and this wear is currently becoming important as a potential mechanism for the overall wear of cemented total hip replacements. However, the relative micromotion at the stem-cement interface has not been widely reported. In the present study, a new micromotion sensor is developed that is based on the deformation of a strain gauge, and this sensor is used to probe the migration of a polished Exeter stem within a Simplex P cement mantle through an in vitro wear simulation. It is demonstrated that the stem migration value generally increases with an increase in the number of loading cycles, with a gradual decrease of migration rate. Additionally, fretting wear is successfully replicated on the stem surface, and the micropores in the cement surface are considered to contribute to initiation and propagation of the fretting damage on the stem. This is confirmed by the observation that no evidence of fretting wear is detected on the stem where the surface is in contact with the pore-free areas on the cement. This study allows a deep insight into the micromotion at the stem-cement interface, and provides evidence highlighting the significance of the micropores in the cement surface in the generation of fretting wear on a polished femoral stem.

The influence of cement mantle thickness and stem geometry on fatigue damage in two different cemented hip femoral prostheses

Experimental models can be used for pre-clinical testing of cemented and other type of hip replacements. Total hip replacement (THR) failure scenarios include, among others, cement damage accumulation and the assessment of accurate stress and strain magnitudes at the cement mantle interfaces (stem-cement and cement-bone) can be used to predict mechanical failure. The aseptic loosening scenario in cemented hip replacements is currently not fully understood, and methods of evaluating medical devices must be developed to improve clinical performance. Different results and conclusions concerning the cement micro-cracking mechanism have been reported. The aim of this study was to verify the in vitro behavior of two cemented femoral stems with respect to fatigue crack formation. Fatigue crack damage was assessed at the medial, lateral, anterior and posterior sides of the Lubinus SPII and Charnley stems. All stems were loaded and tested in stair climbing fatigue loading during one million cycles at 2 Hz. After the experiments each implanted synthetic femur was sectioned and analyzed. We observed more damage (cracks per area) for the Lubinus SPII stem, mainly on the proximal part of the cement mantle. The micro-cracking formation initiated in the stem–cement interface and grew towards the direction of cortical bone of the femur. Overall, the cement–bone interface seems to be crucial for the success of the hip replacement. The Charnley stem provoked more damage on the cement–bone interface. A failure index (maximum length of crack/maximum thickness of cement) considered was higher for the cement–stem interface of the Lubinus SPII stem. For a cement mantle thickness higher than 5 mm, cracking initiated at the cement–bone interface and depended on the opening canal process (reaming procedure and instrumentation). The analysis also showed that fatigue-induced damage on the cement mantle, increasing proximally, and depended on the axial position of the stem. The cement thickness is an important factor for the success of THR and this study evidenced that cement thickness higher than 2 mm apparently does not affect the mechanical behavior of the cement mantel and induce more crack formation on the cement–bone interface.

The importance of a thick cement mantle depends on stem geometry and stem—cement interfacial bonding

The thickness of the cement mantle around the femoral component of total hip replacements is a contributing factor to aseptic loosening and revision. Nevertheless, various designs of stems and surgical tooling lead to cement mantles of different thicknesses. Opinion is divided on whether a thick mantle enhances implant longevity. This study investigates the effect of cement mantle thickness on accumulated damage in the cement, and how this is influenced by the presence or absence of a proximal collar and on whether the stem-cement interface remains bonded. Three-dimensional finite element simulations incorporating creep and non-linear damage accumulation were performed to investigate cracking in the cement mantles around Stanmore Hips under physiologically informed stair-climbing and gait loads. Cement mantle thickness, stem-cement interfacial bonding, and collar design were varied to assess the interactive effects of these parameters. In all cases, damage levels were three to six times higher when the stem-cement interface remained bonded. Cement mantle thickness had little effect on cement damage accumulation around debonded collared stems but was critical in both bonded and collarless cases, where a thicker mantle reduced cement cracking. Damage around a smooth debonded stem with a collar is thus much less sensitive to cement thickness than around bonded or collarless stems.

What results in fretting wear on polished femoral stems

Fretting wear on polished femoral stems has previously been observed in retrieval studies, and it is showing an increasing significance in the overall wear of cemented total hip replacement. However, the initiation and propagation process of this wear has not been fully understood, with shrinkage bumps and micropores in the cement surface being potential participants. In the present study, these two factors are investigated through a finite element analysis to determine which contributed more to fretting wear. A 2D finite element model was created to represent the stem–cement interface, and physiological loading was applied on the femoral stem to simulate the situation during patient walking. The analysis indicated that the functionality of the shrinkage bumps was incidental in comparison with the micropores as the relative micromotion between the femoral stem and the shrinkage bumps was significantly lower than that between the femoral stem and the micropores. Additionally, the influence of micropore size and loading level on generation of fretting wear was further investigated, and an effective method was proposed to retard fretting wear and to improve the survivorship of cemented total hip replacement. This study theoretically validated the potential contribution of the micropores to generation of fretting wear.

In vitro fatigue crack analysis of the Lubinus SPII cemented hip stem

Fatigue damage of cement mantle of cemented hip replacements has been extensively studied. Different conclusions concerning the micro-cracking mechanism has been reported. An in vitro study on commercial cemented synthetic femurs was conducted to determine if micro-cracking formation of the cement mantle would preferentially be at the cement–stem interface or at the bone–cement interface. A stair climbing fatigue loading cycle was applied during one million cycles at 2 Hz on commercial stems. Three hip replacements with the Lubinus SPII cemented stem were studied. After the experiments each femur was sectioned at eleven sections, with an average of 5 and 10 mm of offset between each one of them and analysed with dye liquid penetrates. The results (micro-cracking and debonding) were influence by the geometries of the reamer and the stem and by technical replacement procedure. The micro-cracking formation initiated at the stem–cement interface towards the cortical bone of the femur. For a cement mantle thickness of more than 5 mm, cracking initiated at the cement–bone interface and depended on the geometry of the reamer. At the medial side of the femur more significant cracks and accumulated damage was observed at the stem–cement interface. Correlation between the formation of cracks and minimum cement thickness was determined. A critical cement mantle thickness was observed for 0.5 mm, where a relevant sign of damage was assessed. The analysis of crack-density and accumulated damage showed that fatigue induced cement damage and depended on the axial position of the stem and increase proximally.

Measurement of transient and residual stresses during polymerization of bone cement for cemented hip implants

The initial fixation of a cemented hip implant relies on the strength of the interface between the stem, bone cement and adjacent bone. Bone cement is used as grouting material to fix the prosthesis to the bone. The curing process of bone cement is an exothermic reaction where bone cement undergoes volumetric changes that will generate transient stresses resulting in residual stresses once polymerization is completed. However, the precise magnitude of these stresses is still not well documented in the literature. The objective of this study is to develop an experiment for the direct measurement of the transient and residual radial stresses at the stem–cement interface generated during cement polymerization. The idealized femoral-cemented implant consists of a stem placed inside a hollow cylindrical bone filled with bone cement. A sub-miniature load cell is inserted inside the stem to make a direct measurement of the radial compressive forces at the stem–cement interface, which are then converted to radial stresses. A thermocouple measures the temperature evolution during the polymerization process. The results show the evolution of stress generation corresponding to volumetric changes in the cement. The effect of initial temperature of the stem and bone as well as the cement–bone interface condition (adhesion or no adhesion) on residual radial stresses is investigated. A maximum peak temperature of 70 °C corresponds to a peak in transient stress during cement curing. Maximum radial residual stresses of 0.6 MPa in compression are measured for the preheated stem.

Understanding initiation and propagation of fretting wear on the femoral stem in total hip replacement

The femoral stem–bone cement interface in total hip replacement is supposed to experience low amplitude oscillatory micromotion under physiological loading, consequently leading to fretting wear on the stem surface, which nowadays is considered to play an important part in the overall wear of cemented prosthesis. However, initiation and propagation of fretting wear has been poorly documented and a better understanding concerning this issue has not been established as yet. This present study, on the basis of a profound surface investigation of a polished Exeter V40™ femoral stem and Simplex P bone cement obtained from an in vitro wear simulation, demonstrated that the edges of the micropores in the cement surface matched pretty well to the boundaries of the worn areas on the stem surface. This would indicate that these micropores contributed significantly to the fretting process at the stem–cement interface.

Femoral stem wear in cemented total hip replacement

The great success of cemented total hip replacement to treat patients with endstage osteoarthritis and osteonecrosis has been well documented. However, its long-term survivorship has been compromised by progressive development of aseptic loosening, and few hip prostheses could survive beyond 25 years. Aseptic loosening is mainly attributed to bone resorption which is activated by an in-vivo macrophage response to particulate debris generated by wear of the hip prosthesis. Theoretically, wear can occur not only at the articulating head-cup interface but also at other load-bearing surfaces, such as the stem-cement interface. Recently, great progress has been made in reducing wear at the head-cup interface through the introduction of new materials and improved manufacture; consequently femoral stem wear is considered to be playing an increasingly significant role in the overall wear of cemented total hip replacement. In this review article, the clinical incidences of femoral stem wear are comprehensively introduced, and its significance is highlighted as a source of generation of wear debris and corrosion products. Additionally, the relationship between femoral stem surface finish and femoral stem wear is discussed and the primary attempts to reproduce femoral stem wear through in-vitro wear testing are summarized. Furthermore, the initiation and propagation processes of femoral stem wear are also proposed and a better understanding of the issue is considered to be essential to reduce femoral stem wear and to improve the functionality of cemented total hip replacement.

Integrity of the stem‐cement interface in THA: Effects of stem surface finish and cement porosity

No consensus exists for the optimal surface finish on cemented total hip prosthesis stems. The purpose of this study was to determine the effects of stem finish and interfacial cement porosity on the integrity of the stem-cement interface. Simulated stems made of Co-Cr, having polished or matte surfaces, at room temperature or heated to 37 degrees C, were cemented into Sawbones simulated femurs. Push out testing of the stem-cement interface was performed immediately after cement polymerization and after two aging periods in 37 degrees C saline or 37 degrees C air, and the extent of interfacial porosity at the stem-cement interface was determined. Polished stems exhibited an average 60% greater interfacial strength than that of matte stems initially and up to 240% after aging treatments. Cement porosity at the stem-cement interface and incomplete cement interdigitation into surface asperities on matte stems likely allowed saline penetration into the stem-cement interface during wet aging, resulting in a rapid decrease of shear strength. Stem preheating to 37 degrees C virtually eliminated interfacial pores and resulted in greater shear strengths regardless of surface finish. Polished stem surfaces with stem preheating provided the best interfacial shear strength and sealing ability against saline penetration into the stem-cement interface and could result in increased longevity of stem fixation.

Collarless polished tapered stem

We retrospectively reviewed 175 patients (191 hips) who had undergone primary cemented total hip replacement between November 1992 and November 1995 using a collarless polished double-tapered femoral component after a minimum of ten years (mean 11.08; 10 to 12.8). All stems were implanted using contemporary cementing techniques with a distal cement restrictor, pressurised lavage, retrograde cementing with a gun and proximal pressurisation. Clinical outcome was assessed using the Harris Hip score. Radiological analysis was performed on calibrated plain radiographs taken in two planes. Complete radiological data on 110 patients (120 hips) and clinical follow-up on all the surviving 111 patients (122 hips) was available. The fate of all the hips was known. At final follow-up, the mean Harris Hip score was 86 (47 to 100), and 87 of 116 patients (75%) had good or excellent scores. Survival with revision of the stem for aseptic loosening as the endpoint was 100%; and survival with revision of the stem for any reason was 95.9% (95% confidence interval 87.8 to 96.8) at ten years. All the stems subsided vertically at the stem-cement interface in a predictable pattern, at an overall mean rate of 0.18 mm per year (0.02 to 2.16), but with a mean rate of 0.80 mm (0.02 to 2.5) during the first year. The mean total subsidence was 1.95 mm (0.21 to 24). Only three stems loosened at the cement-bone interface. There was excellent preservation of proximal femoral bone stock. There was a high incidence of Brooker III and IV heterotopic ossification affecting 25 patients (22%). The collarless polished tapered stem has an excellent clinical and radiological outcome at a minimum of ten years' follow-up. The pattern and magnitude of subsidence of the stem within the cement mantle occurred in a predictable pattern, consistent with the design philosophy.

Fatigue failure analysis of a specific total hip prosthesis stem design

In an attempt to achieve initial stability and lack of motion at the cement stem interface, a specific design of the hip prosthesis femoral component was conceived. This design incorporated a specific geometrical feature in the prosthesis stem, namely a screw-like cross section profile. This feature was employed to avoid axial motion as well as stem subsidence into the cement mantle. Based on the numerical simulation results, this investigation reveals that the prosthesis unique design was not responsible for the stem loosening. Once the stem has been loosed, however, the concentration of stress at the geometrical feature root was sufficient to nucleate and propagate a fatigue crack, which eventually culminate in the femoral component catastrophic failure.

Reproduction of fretting wear at the stem—cement interface in total hip replacement

The stem-cement interface experiences fretting wear in vivo due to low-amplitude oscillatory micromotion under physiological loading, as a consequence it is considered to play an important part in the overall wear of cemented total hip replacement. Despite its potential significance, in-vitro simulation to reproduce fretting wear has seldom been attempted and even then with only limited success. In the present study, fretting wear was successfully reproduced at the stem-cement interface through an in-vitro wear simulation, which was performed in part with reference to ISO 7206-4: 2002. The wear locations compared well with the results of retrieval studies. There was no evidence of bone cement transfer films on the stem surface and no fatigue cracks in the cement mantle. The cement surface was severely damaged in those areas in contact with the fretting zones on the stem surface, with retention of cement debris in the micropores. Furthermore, it was suggested that these micropores contributed to initiation and propagation of fretting wear. This study gave scope for further comparative study of the influence of stem geometry, stem surface finish, and bone cement brand on generation of fretting wear.

Vacuum-mixing cement does not decrease overall porosity in cemented femoral stems

The role of vacuum mixing on the reduction of porosity and on the clinical performance of cemented total hip replacements remains uncertain. We have used paired femoral constructs prepared with either hand-mixed or vacuum-mixed cement in a cadaver model which simulated intra-operative conditions during cementing of the femoral component. After the cement had cured, the distribution of its porosity was determined, as was the strength of the cement-stem and cement-bone interfaces. The overall fraction of the pore area was similar for both hand-mixed and vacuum-mixed cement (hand 6%; vacuum 5.7%; paired t-test, p = 0.187). The linear pore fractions at the interfaces were also similar for the two techniques. The pore number-density was much higher for the hand-mixed cement (paired t-test, p = 0.0013). The strength of the cement-stem interface was greater with the hand-mixed cement (paired t-test, p = 0.0005), while the strength of the cement-bone interface was not affected by the conditions of mixing (paired t-test, p = 0.275). The reduction in porosity with vacuum mixing did not affect the porosity of the mantle, but the distribution of the porosity can be affected by the technique of mixing used.

Influence of femoral stem surface finish on the apparent static shear strength at the stem–cement interface

The stem–cement interface has long been implicated in failure of cemented total hip replacement. Much research has been performed to study the factors affecting the bond strength between the femoral stem and the bone cement. The present study aims to further investigate the influence of femoral stem surface finish on the apparent static shear strength at the stem–cement interface through a series of pull out tests, where stainless steel rods are employed to represent the femoral stem. The results demonstrated that there was a general tendency for the apparent static shear strength to be increased with the rise of surface roughness. The polished and glass bead-blasted rods illustrated a slip-stick-slip failure whereas the shot-blasted and grit-blasted rods displayed gross interface failure. Following pull out test, cement transfer films were detected on the polished rods, and there was cement debris adhered to the surface of the grit-blasted rods. Micropores, typically 120 μm in diameter, were prevalent in the cement surface interfaced with the polished rods, and the cement surfaces in contact with the shot-blasted and grit-blasted rods were greatly damaged. There was also evidence of metal debris embedding within the cement mantle originating from the tests of the grit-blasted rods, indicating an extremely strong mechanical interlocking at the interface. In summary, this present research demonstrated that the grit-blasted rods with the highest surface roughness were the best in terms of apparent static shear strength. However, it seemed to be most applicable only to the stem designs in which mechanical interlocking of the stem in the initial fixed position was essential.

Static shear strength between polished stem and seven commercial acrylic bone cements

The stem-cement interface is one of the most significant sites in cemented total hip replacement and has long been implicated in failure of the whole joint system. However, shear strength at this interface has rarely been compared across a range of commercially available bone cements. The present study seeks to address this issue by carrying out a comparative study. The results indicated that the static shear strength was more dependent on cement type than cement viscosity and volume. However, both cement type and viscosity were contributory factors on porosity and micropore size in the cement surface. There was no significant difference between Simplex P and Simplex P with Tobramycin. Although the bone cements were all hand mixed in this study, the static shear strength was significantly larger than the values recorded by other researchers, and the porosity and micropore size showed much lower values. Bone cement transfer films were detected on the stem surface, typically about 4-10 mum thick. They were considered to be an important factor contributing to high friction at the stem-cement interface after initial debonding.