In this paper, a nonlinear three dimensional all-aspect guidance law, to intercept maneuvering target at pre-specified orientation, is presented. Without decoupling the engagement kinematics into two perpendicular planes, the proposed guidance law is derived in three dimensions directly. More importantly, the proposed strategy is an ‘all-aspect’ guidance law, which allows missile to intercept the target at the desired impact angle, even in the presence of very large initial pointing errors. First, in order to design a guidance law with all-aspect interception capability, the collision conditions analysis process is carefully developed and an additional necessary constraint condition is derived. Then, based on chattering reduction sliding mode control, a nonlinear three dimensional terminal impact angle constrained guidance law is derived considering maneuvering targets. After capturability analysis, an additional sliding mode surface and a switching logic are further designed, so that the all-aspect capability is guaranteed. Finally, numerical simulations are provided to demonstrate the effectiveness of the proposed guidance strategy.