Aiming to improve the structural behavior of high-rise buildings, a steel-plate encased concrete shear wall with parallel circular concrete-filled steel tube columns (P-CFST-SCSW) is proposed and investigated by experiments and numerical studies in this study. All seven specimens were conducted and tested under reversed cyclic force to explore the influences of different design parameters, including axial compression ratios, steel tube thicknesses, spacing-thickness ratios, and shear span ratios. The failure modes, hysteresis behavior, strength and stiffness degradation, energy dissipation were thoroughly recorded and compared in detail. Results indicated that all specimens have experienced the failure process of boundary steel tubes buckling, steel plates buckling and concrete crushing. Results also showed that the bearing capacity and deformation capacity of proposed composite walls was excellent. The peak force and initial stiffness of P-CFST-SCSWs were improved by reducing the shear span ratio and increasing the axial compression ratio, while the stiffness degradation and ductility quickly deteriorated. The increased thickness of circular steel tubes considerably improves the seismic behavior of P-CFST-SCSWs. Finally, the numerical model was established to further investigate the effect of the concrete strength, steel yielding strength, and circular CFST columns number on lateral behavior of P-CFST-SCSWs.