Kuosheng Nuclear Power Plant in Taiwan is a GE-designed twin-unit BWR/6 plant, each unit rated at 2894 MWt. In this study, we presented the calculated results of the containment pressure and temperature responses after the main steam line break accident, which is the design basis for the containment system. During the simulation, a power of SPU range (105.1%) was used and a model of the Mark III type containment was built using the containment thermal-hydraulic program GOTHIC. The simulation consists of short and long-term responses. The drywell pressure and temperature responses which display the maximum values in the early state of the LOCA were investigated in the short-term response; the primary containment pressure and temperature responses in the long-term response. The blowdown flow was provided by FSAR and used as boundary conditions in the short-term model; in the long-term model, the blowdown flow was calculated using a GOTHIC built-in homogeneous equilibrium model. In the long-term analysis, a simplifier RPV model was employed to calculate the blowdown flow. Finally, the calculated results, similar to the FSAR results, indicate the GOTHIC code has the capability to simulate the pressure/temperature response of Mark III containment to the main steam line break LOCA.