This study addresses the pressing issues of groundwater depletion and drought problems in the Erbil basin, a vital resource region in the Middle East. Focused on an area of strategic importance due to its large size and critical water resources, the study employs the Groundwater Modeling System (GMS) software to create a detailed 3D hydrogeological model based on extensive borehole data. With over 240 boreholes analyzed, the study strategically selects 70 accurate wells drilled by the Groundwater Directorate. The construction of the 3D stratigraphic models for the Erbil basin relies on three main historical data including boreholes, geological formations and a comprehensive approach, incorporating deep well logging data and the definition of distinct geological layers. By discerning the presence of previous and impervious layers, the model effectively categorizes the aquifer types within the Erbil basin. The aquifer system is delineated based on stratigraphic units, designating materials with high conductivity (silt, sand, and gravel) as aquifers and clay (or claystone) as aquitards. A 3D steady-state groundwater flow model is successfully executed, employing PEST pilot point for automated parameter estimation. The model, validated with a coefficient of determination (R2) of 0.9998, reveals hydraulic conductivity values ranging from 0.000980705 to 100 m/day and a recharge value of 0.000976443 m/day. The study classifies Erbil's aquifer types as unconfined, confined, and semi-confined, providing a valuable foundation for groundwater management. The primary objective of this study is to construct a calibrated numerical groundwater model for the multi-aquifer system in the Erbil basin. The model aims to serve as a robust tool for analyzing the sustainability of diverse groundwater infrastructure development strategies within the region. The Erbil basin poses unique challenges for groundwater modeling, marked by a scarcity of critical data such as monitoring well information, pumping rates, recharge rates, and flow budgets. In response to these limitations, the study adopts an innovative approach by integrating in situ data with earth observation data. The integration of these datasets seeks to overcome data constraints and enhance the accuracy of the groundwater model. By achieving calibration and validation of the numerical model, this research strives to provide a valuable resource for decision-makers, planners, and stakeholders involved in groundwater management in the Erbil basin. Ultimately, the study aims to contribute to the development of sustainable and effective strategies for the utilization and preservation of groundwater resources in this vital region and also to enhance practical management strategies for the Erbil groundwater basin, ensuring sustainable utilization of the crucial sub-surface water resources, an objective successfully achieved through this research.