This study examines relationship between the residents’ Socio-economic Status (SeS) and choices in the adoption of anti-burglary devices across the residential zones of Ogbomoso City. It surveys households’ houses and their environments across the Core, Intermediate and Suburb residential zones of the study area. The variables used to examine the analysis of installed anti-burglary devices include the adoption of iron / steel bar, electronic devices, wire mesh, ethno-medical, and others. The examination of the aforementioned devices in relation to the socio-economic status of residents using Spearman’s rho Correlation analysis revealed that there is positive correlation between monthly income of residents and all the housing anti-burglary devices adopted with the p-values of 0.000, 0.010, 0.000, and 0.014 for Iron/steel bar, electronic devices, wire mesh and ethno-medical devices respectively. It further revealed that education has a significant correlation but negative with ethno-medical devices due to the p-value of 0.051and r-value of -0.070. This implies that increase in education reduces the use of ethno-medical devices in the study area. The study concluded that Socio-economics Status of residents have a great influence on the type and choice of anti-burglary devices adopted in the fight against residential burglary and home invasion across the City.