Statistical Program Research Articles

Pengaruh Kualitas Pelayanan dan Citra Destinasi terhadap Kepuasan Pengunjung dan Loyalitas Pengunjung Destinasi Pantai Lon-Malang

This research aims to determine the influence of service quality and destination image on visitor satisfaction and loyalty of visitors to the Lon Malang Beach destination. This research uses a quantitative approach with analytical methods Structural Equation Modeling (SEM), which is processed using a statistical program SmartPLS version 4. The population in this study consisted of tourists who visited Lon Malang Beach, with a sample size of 100 respondents selected randomly. The main instrument used in data collection was a questionnaire prepared using a Likert scale to measure respondents' perceptions of the variables studied. The research results show that service quality has a significant influence on visitor loyalty, making it the main factor that plays an important role in increasing tourist loyalty at Lon Malang Beach. In addition, destination image was found to have a smaller influence on visitor satisfaction and loyalty compared to service quality. Visitor satisfaction has also been proven to be an important variable in building loyalty, meaning satisfied visitors are more likely to return to visit in the future. Thus, this research highlights that service quality is a key factor in creating visitor loyalty, while destination image makes a more limited contribution to visitor satisfaction and loyalty at Lon Malang Beach.

Integration of Circular Economy and Urban Metabolism for a Resilient Waste-Based Sustainable Urban Environment

An unsustainable rate of resource production and consumption is evident in urban environments. The absence of innovative approaches in conjunction with the exponential urbanization and expansion of the global population will inevitably result in substantial environmental consequences. There are two emerging alternatives: circular economy (CE) and urban metabolism (UM). The integration of these principles into novel methodology casts doubt on the linear model of contemporary economic and urban systems, which includes extraction, production, utilization, and disposal. In the development of a distinctive urban framework known as circular urban metabolism, the current study has illustrated the application of these principles. We design this study to motivate urban planners and decision-makers to investigate, develop, and supervise ecologically sustainable cities. Scholars from a variety of academic disciplines, intrigued by the intricacies of urban planning, design, and administration, can foster interdisciplinary collaboration in the circular urban metabolism (CUM) region. To address the research question, we implemented a bibliometric analysis, which involved the examination of 627 pertinent research papers, utilizing the R (R 3.6.0+) statistical programming language. The results emphasize the fundamental characteristics and significance of CUM in the management of refuse. In addition, the findings underscore the importance of creating a novel framework that incorporates the principles of urban political ecology, CUM, sustainability, and the novel dimension of waste metabolism. It is the goal of this framework to emphasize the significance of recycling in the informal sector as a waste management strategy in low- and medium-income countries (LMICs).

체육전공 대학생의 전공만족도와 무경계진로태도가 진로탄력성에 미치는 영향

Objectives The purpose of this study is to investigate the impact of major satisfaction and boundary-less career attitude of college students majoring in physical education on career elasticity, suggest measures to promote employment of college students majoring in physical education, and provide basic data necessary for employment guidance for college students majoring in physical education. It is in Methods 450 students from the sports departments of three universities located in Daegu and North Gyeongsang Province were selected and sampled using the convenience extraction method, and 427 questionnaires were used for the final analysis. Descriptive statistical analysis, frequency analysis, correlation analysis, and multiple regression analysis were conducted using the Windows SPSS Ver 22.0 statistical program. Results First, positive and negative correlations were found between the major satisfaction perceived by college students majoring in physical education, their boundaryless career attitude, and career elasticity. Second, it was found that college students majoring in physical education had a positive effect on perceived major satisfaction and a negative effect on major dissatisfaction. Third, the borderless career attitude perceived by college students majoring in physical education was found to have a positive effect on the sub-factors of career elasticity. Conclusions If we can increase the level of major satisfaction and boundary-less career attitude of college students majoring in physical education, it is believed that this can increase the career elasticity necessary to promote employment of college students majoring in physical education, and it can be useful for leaders in guiding college students majoring in physical education toward employment. You will be able to use it.

The Impact of Foreign Direct Investment, Trade Value on the Economic Growth of Greater Mekong Subregion (GMS)

In the study entitled “The impact of foreign direct investment, trade value on the economic growth of the Greater Mekong Subregion countries” which aims to study the changes of foreign direct investment, trade value on the economic growth of the Greater Mekong Subregion countries (GMS) from 2005–2022, and analyze the impact of foreign direct investment, trade value on the economic growth of the Greater Mekong Subregion countries (GMS), The data used in the study is geographical data. This study uses descriptive statistics to analyze changes and uses the estimation method of ordinary least squares (OLS) through a statistical program. Through the analysis of changes in foreign direct investment, trade value, and gross domestic product of GMS, it was found that, since GMS was established in 1992, the condition of foreign direct investment, trade value, and gross domestic product of GMS has been changing continuously due to the influence of Chinese investment that has come to invest in the region in terms of transportation infrastructure and electricity. In terms of trade, there are trade relations among the group of GMS countries, focusing on facilities for transportation and trade in the region. Cooperation in the region, contributing to economic growth and reducing poverty, as well as responding to the demand for products in the region, developing agriculture in urban areas, promoting GMS as a tourist source, and making the total domestic product of the countries in the region grow. A temporary drop in foreign direct investment, trade value, and gross domestic product of the GMS is due to the Mekong Delta member countries being affected by the financial crisis in Asia, political unrest, the financial crisis in China, and the spread of the COVID-19 disease. Analysis of the effect of foreign direct investment and trade value on the economic growth of the GMS countries by testing the relationship found that both the value of foreign direct investment and the value of international trade are related in the same direction to economic growth: if the value of foreign direct investment in the GMS countries increases by 1%, it will result in an increase in the total domestic product by 0.1225%, and if the value of trade in the GMS countries increases by 1%, it will result in an increase in the total domestic product by 0.7566% through statistical significance of 0.01.

The Impact of Demographic Change on Economic Growth in ASEAN

To study the impact of Demographic Change on Economic Growth in ASEAN. This study uses panel data from 1993 to 2022 from ASEAN countries by collecting data from the World Development Indicator, World Bank 2023, consisting of GDP per capita, working age population, Youth dependency population, and Elderly dependency population. We utilize the statistical completion program as a tool to help with the Panel Autoregressive Distributed Lag Approach (ARDL) method analysis. The results of the study found that variables are stationary at I(0) and I(1) level. Moreover, the estimated coefficients of the variables with the Pooled Mean Group reveals that Working age population had a positive impact in long-run on the GDP per capita in ASEAN countries, Youth dependency population had a negative impact in long-run on the GDP per capita in ASEAN countries, and also had a speed of adjustment to long-run equilibrium and for Elderly dependency population were not statistically significant. The result of Mean Group and Dynamic Fixed Effect further shows that there were not statistically significant. By means of the Hausman test, the results can be concluded that Pooled Mean Group estimation is most suitable.

The Impact of Social Media Marketing on Consumer Purchase Intention and Customer Loyalty on E-commerce Websites

Thailand’s e-commerce industry has significantly improved in recent years, driven by widespread Internet access and smartphone adoption. The diverse online marketplace caters to the changing needs and preferences of Thai consumers. However, the impact of social media marketing on consumer purchase intention and loyalty to e-commerce sites has not received sufficient attention. This study focuses on online shopping platforms in Thailand to investigate the role of social media marketing in influencing consumer purchase intention and loyalty to e-commerce platforms. For this purpose, 400 online questionnaires were required for data collection and used for testing the hypothesis, based on the suitable statistics through the advanced statistical program. The findings indicated that demographic factors, consumer behavior, and social media engagement have significantly influenced consumer purchase intention. This research also highlighted implications for how e-commerce sites can enhance their marketing strategies and foster customer loyalty to their products. Keywords: social media marketing, purchase intention, customer loyalty

Participating in the Production of Silk Handicrafts in Phonxay Village, Luangprabang City

This study aim to study the participation in the production of silk handicrafts in Phon Xai Village, Luangprabang District, as a quantitative research which used questionnaires to collect data from a sample group of 98 people and analyze the data with the statistical program SPSS version 20. The results of the study found that people are most involved in the production and service of silk products, participation in marketing, participation in skills in silk production, and participation in administration and management Production of silk with the average total value is between 0.36-0.42 and the standard deviation is between 0.10-0.65. People are involved in the medium level of participation in the use of information technology and participation in the use of internal potential in production and services, with an average

8주간 유산소운동이 여고생의 신체구성과 정신건강에 미치는 영향

Objectives This study aims to investigate the effects of an 8-week aerobic exercise program on the body composition and mental health of high school girls. Methods To achieve the purpose of the study, a total of 35 high school girls participated, with 17 assigned to the exercise group and 18 to the control group through random allocation. The exercise group performed aerobic exercise three times a week for 60 minutes each session over an 8-week period, while the control group maintained their usual daily activities during the same period. Repeated measures ANOVA was conducted using the SPSS 23 statistical program to examine the differences between the groups, and the significance level was set at .05. Results The exercise group showed a statistically significant decrease in body fat percentage (p=.001) and a statistically significant improvement in mental health (p=.016). Conclusions Aerobic exercise positively impacts the body composition and mental health of high school girls, enhancing their overall well-being. It not only brings about physical changes but also helps to improve emotional stability. Therefore, in order to improve the health and quality of life of high school girls, various aerobic exercise programs are developed, and customized designs are needed considering interest and persistence. Such programs comprehensively support the physical and mental health of adolescents and contribute to building a healthier society in the long term.

WHOLE BRAIN RADIOTHERAPY FOR INTRACRANIAL METASTATIC DISEASE IN NON-SMALL CELL LUNG CANCER: THE WESSEX EXPERIENCE

Abstract AIMS The QUARTZ trial (2016) reported that corticosteroid therapy was non-inferior to whole brain radiotherapy(WBRT) for non-small cell lung cancer (NSCLC) with regards overall survival(OS). This is a single centre experience of WBRT for NSCLC in the post-QUARTZ era and in the context of the changes in clinical practice over the past 8 years. METHOD Single centre retrospective observational study. Patients included with NSCLC treated with WBRT for radiologically confirmed intracranial (IC) metastatic disease January 2018 to December 2022. OS, baseline tumour/patient characteristics and lines of treatment were recorded from medical records. Data compiled using Excel and statistical analysis using the R language for statistical programming. RESULTS 62 patients were included, median age 64 (37 -82). 29(46.8%) were Performance status 0-1. 50(80.6%) received 20Gy in 5 fractions, 12(19.4%) received 30Gy in 10 fractions. PDL1 >50% in 14(22.6%), EGFR mutation positive in 10(16.1%), 0(0%) ALK/ROS mutations. 9(14.5%) had received prior radiotherapy(RT) for IC disease (SRS:8, partial brain VMAT:1). 20(32.3%) had IC disease at presentation. Median OS 68 days (95%CI:58-111;range12-777) in keeping with QUARTZ results (median OS 65 days, 95%CI:50- 78). Univariate analyses demonstrated: subsequent systemic therapy (p=0.0022), receiving immunotherapy (p=0.002) and baseline performance status (p=0.0017) associated with improved OS. PDL1 >50%, EGFR mutation positive, RT dose, prior systemic therapy, histological subtype, presence of a targetable mutation, first or subsequent IC treatment did not predict survival. The chi-squared test was used to compare differences in the groups with OS>100days(n=22) and OS<100days(n=40). Systemic therapy after WBRT(p=0.0011) and immunotherapy treatment(p=0.0092) were significant differences between the cohorts and associated with improved survival. CONCLUSION This data supports conclusions of QUARTZ study and it remains difficult to define a role for WBRT in the management of IC disease in NSCLC. There is a cohort who have better OS, though we believe this may be related to systemic therapy (particularly immunotherapy) exposure.

Immunohistochemical expression of PD-L1 in esophageal carcinoma and its correlation with histopathological features

Background: Carcinoma of the esophagus poses a considerable medical and public health challenge in many parts of the world. Despite advances in screening and multimodal management of this disease, overall survival remains poor. There is an utmost need to find a marker for the establishment of targeted immunotherapy. One immunohistochemical marker that has surfaced with the advent of anti-PDL1 immunotherapy is PD-L1 which has been proven to be advantageous. This study aimed to determine PD-L1 expression and its correlation with the grade of tumor and other histopathological parameters in 50 patients. Materials and Methods: A cross-sectional study was conducted on 50 cases of histopathologically proven esophageal carcinoma. Antibody used for PD-L1 was rabbit monoclonal (CAL10) Biocare. PD-L1 expression was considered positive when a complete or partial membranous or cytoplasmic staining pattern was noted in more than 5% of tumor cells. Correlation between PD-L1 expression and clinicopathological parameters was calculated. Proper consent was taken. The findings of the study were statistically analyzed using Statistical Package for the Social Sciences (SPSS) software version 21.0, a statistical program for Microsoft Windows. Results: This study revealed that PD-L1 positivity increases as the histopathological grade of esophageal squamous cells increases. Conclusions: The expression of PD-L1 increases with grade and shows more positive expression in poorly differentiated tumors. This indicates that PD-L1 overexpression is associated with aggressive disease. Targeted therapy against PD-L1 may prove to be beneficial in such patients.

The Impact of Types of Financial Decisions on Strategic Flexibility (Analytical Study of a Sample of Iraqi Commercial Banks)

The current research aims to study the impact of financial decisions represented by in its dimensions (Dividend Distribution Resolution decision Planning and forecasting) and its effect on Strategic flexibility represented by its dimensions(Resource flexibility, Flexibility of capabilities) Through an analytical study of a sample of Iraqi commercial banks, and for the purpose of identifying financial decisions and the extent of their impact on strategic flexibility, in addition to the tireless efforts made by the banks’ management, this research came as a contribution in this field, and the purpose was to test the research hypotheses, and the researcher distributed (150) questionnaires to a sample of employees who are at the level of (General Manager, Assistant General Manager, head of Department, head of Division, Head of Financial Unit) in the aforementioned field. (119) questionnaires were retrieved from them, and some of them were not Valid. (23) one Valid questionnaires represent (96) of the total distributed questionnaires, and they were analyzed using the statistical program (23. SPSS V). The study concluded with a set of conclusions, the most important of which are: Flexibility Strategy The characteristics of the commercial banks included in the study came at an average evaluation level for the variable as a whole, as well as for both dimensions that make up this variable, which explains that these banks are characterized by an average degree of flexibility. Strategy Regarding the two dimensions that make up this variable: Based on the recommendations presented by this study and its results, the researcher presented a set of studies proposed to be conducted in the future, such as conducting a study on the complementary relationship between financial decisions and flexibility. ....

Physical attributes of the soil in an area under Forage Palm management in the Agreste of Alagoas

The objective was to evaluate soil density (Ds) and penetration resistance (RP) in an experimental area with forage palm management. The study was conducted in an experimental area belonging to the Federal University of Alagoas - Arapiraca Campus. To determine the Ds, undeformed samples were collected at three points within the plot, each point with three different depths (0-10; 10-20 and 20-30 cm). To determine the PR, the impact penetrometer was used at depths of 0-60 cm. For comparison purposes, samples were collected in a native forest area. The data were submitted to analysis through the statistical program R and Tukey test at 1 and 5% probability. Ds ranged from 1.59 to 1.63 g cm-3, not differing significantly. The lowest densities were obtained in the surface layer, influenced by the contribution of organic matter and greater presence of roots. In all depths evaluated, the Ds values were lower for the native forest area. In relation to PR, the values gradually increased up to the first 20 cm of depth for most treatments, reflecting the influence that the non-soil revolution causes in the most superficial layers. Therefore, Ds did not differ significantly. The 0-10 cm layer showed the lowest Ds values. The native forest showed the lowest Ds values at all depths when compared to the managed area. PR gradually increased to the first 20 cm of depth for most of the treatments analyzed.

The Effect of Pricing and Promotion on Online Advertising on Social Media on Buying Interest in Wedding packages at Alila Villas Uluwatu

The sample of this study consisted of 100 people who were selected as respondents. Data was collected through a questionnaire using a Likert scale. This study uses the SPSS version 25 statistical program to analyze the data. The analysis includes testing data quality (validity and reliability), fulfilling classical assumptions, and modeling the relationship between variables using multiple linear regression analysis. The t and F hypothesis tests were used to test the significance of the model and regression coefficients. The research findings found a positive and significant influence of pricing and online advertising on social media on the interest in buying a wedding package at Alila Villas Uluwatu. The results of this study indicate that the Price Variable (X1) and Online Advertising (X1) simultaneously have a positive and significant effect on buying interest (Y) wedding packages at Alila Villas Uluwatu. The sample of this study consisted of 100 people who were selected as respondents. Data was collected through a questionnaire using a Likert scale. This study uses the SPSS version 25 statistical program to analyze the data. The analysis includes testing data quality (validity and reliability), fulfilling classical assumptions, and modeling the relationship between variables using multiple linear regression analysis. The t and F hypothesis tests were used to test the significance of the model and regression coefficients. The research findings found a positive and significant influence of pricing and online advertising on social media on the interest in buying a wedding package at Alila Villas Uluwatu. The results of this study indicate that the Price Variable (X1) and Online Advertising (X1) simultaneously have a positive and significant effect on buying interest (Y) wedding packages at Alila Villas Uluwatu.

Knowledge and practices of interventional radiology staff regarding radiation protection

Interventional radiology (IR) has become a widespread medical imaging technique, offering minimally invasive treatment options. However, IR procedures can expose patients and staff to substantial radiation risks, necessitating enhanced radiation protection practices. This study aimed to survey the knowledge and practices of interventional radiology staff regarding radiation protection. A cross-sectional study with a descriptive aim, based on a questionnaire was done. The study subjects were all healthcare personnel of all specialties having practiced in interventional radiology between 2019 and 2022 at the University Hospital Center of Rabat. The statistical processing was carried out using Microsoft Excel 2013® and the IBM SPSS Statistical program version 20 (IBM Inc. NY, USA). The results indicated that 59.4% of participants had not received any specific training in radiation protection, and 45% were unaware of the radiation-induced risks associated with interventional radiology procedures. Regarding safety practices, 75% of participants maintained a distance of at least 1 meter from the x-ray source, while only 6% used the lowest possible exposure settings. Concerning the use of radiation protection devices, 87.5% of participants wore a lead apron, 75% used a thyroid shield, 6.3% wore lead glasses, and 37.5% utilized suspended mobile screens, whereas 12.5% did not use any radiation protection devices. Additionally, 84% of participants wore their personal dosimeter, though not consistently. The knowledge and practices of most interventional radiology personnel are inadequate for effective radiation protection. Regular, ongoing training in radiation safety is essential to improve adherence to protection standards and enhance overall safety in clinical practice.

Impact of childhood trauma history on premenstrual syndrome in women of reproductive age: A cross-sectional study.

Premenstrual syndrome is a women's health problem affecting women of reproductive age. Early traumas may have negative effects on women's health. Childhood traumas are thought to be an important risk factor for the emergence of premenstrual syndrome. The aim of this study was to investigate the relationship between premenstrual syndrome and childhood traumas in women. This is a cross-sectional study. This study was conducted online between September 2023 and January 2024. The sample of the study consisted of 437 women of reproductive age, between the ages of 18-49, who did not have any obstacles to participating in the study. Personal Information Form, Premenstrual Syndrome Scale and Childhood Trauma Scale were used to collect the data. SPPS statistical program was used to analyze the data. The prevalence of premenstrual syndrome was 55.6%. Emotional neglect, physical abuse, emotional abuse and sexual abuse levels were found to be higher in women with premenstrual syndrome (p < 0.05). It was determined that childhood traumas increased the level of premenstrual syndrome in women (ß = 0.266). Childhood trauma explained 6.8% of the total change in premenstrual syndrome level (R2 = 0.068). Emotional neglect (ß = 0.163) and physical abuse (ß = 0.121) increased the level of premenstrual syndrome. Childhood traumas were found to be an important factor affecting the occurrence of premenstrual syndrome and exacerbating its symptoms. Early detection of childhood traumas may prevent long-term problems that may occur in individuals.

Faktor Yang Memengaruhi Pertumbuhan Laba pada Sektor Industri Subsektor Food and Beverage di Indonesia

This study aims to analyze the impact of liquidity, profitability, solvency, and company size on profit growth. In this research, the independent variable liquidity is measured by CR, profitability is measured by NPM, solvency is measured by DER, and company size is measured by the logarithm of total assets. The dependent variable is profit growth. The objects of this research are food and beverage sub-sector companies listed on the Indonesia Stock Exchange. The sampling technique used is purposive sampling, with a total of 9 companies sampled over the period from 2020 to 2023. This study employs multiple linear regression analysis using the Statistical Program for Social Science (SPSS). The results indicate that the liquidity and company size variables negatively affect profit growth, while the profitability variable positively affects profit growth. However, the solvency variable does not impact profit growth. This research can provide insights for companies in formulating policies to enhance their performance by managing assets, debts, and receivables effectively and efficiently to boost profit growth.

The effect of viral anxiety experienced by nurses working in pediatric service on psychological factors during Covid-19 period

During the Covid-19 period, nurses, as healthcare professionals, have been under a great workload, and their anxiety levels have also increased their psychological effects. Therefore, this study was conducted to examine the effect of viral anxiety experienced by nurses working in the pediatric ward during the Covid-19 period on psychological factors. This is a descriptive study. Permission was obtained from Hakkari University Scientific Research and Publication Ethics Committee for research permission. Sociodemographic data were collected online from 1200 nurses working in the pediatric service who voluntarily participated in the study between October 13, 2023 and December 25, 2023 using the sociodemographic data collection form and the stress and anxiety scale for health workers due to virus epidemic-9 items (SAVE-9), Patient health questionnaire-9 (PHQ-9), Obsession with Covid-19 Scale (OCS), Reassurance-seeking behavior scale against coronavirus (CRBS). In order to compare SAVE, PHQ, OCS and CRBS scale scores according to sociodemographic information and vaccination status variables, independent groups t test one-way variance analysis Levene's F test was applied and data were analyzed using a statistical package program. It is understood that 59.9% of the participants are male and 40.1% are female. The proportion of married participants was 95.4%. The results of the scores obtained from the SAVE and PHQ scales show that the stress and anxiety related to the virus epidemic are above the middle level, the result of the OCS scale score shows that the dysfunctional thoughts associated with the coronavirus, and the scores obtained from the CRBS Total scale show that the assurance-seeking behavior is exhibited according to the results. The effect of viral anxiety on the psychological factor according to sociodemographic characteristics (gender, age, marital status, socioeconomic status, educational status, working area in pediatric service, vaccination status) showed significant and different results according to scale scores. It was concluded that the viral anxiety experienced by the nurses working in the pediatric service during the Covid-19 period showed different characteristics in terms of psychological factors and sociodemographic characteristics, and the nurses were not very effective due to the decrease in the effect of Covid-19.

Radiomics in the differential diagnosis of focal brain lesions: a retrospective study

INTRODUCTION: Glioblastoma and solitary metastases are the most common malignant neoplasms of the brain, characterized by high mortality and severe disability in patients. The method of choice for neuroimaging glioblastomas and metastases is contrast-enhanced magnetic resonance imaging. However, differentiation between the two is often difficult due to similar radiological features on MRI. Radiomics and machine learning can differentiate the primary origin of brain metastases and identify pathological tumor types noninvasively.OBJECTIVE: Application of texture analysis for differential diagnosis of glioblastomas and metastases of different etiologies.MATERIALS AND METHODS: 169 MRI studies from the RSCRR database were used in the study, 11 of which visualized morphologically differentiated glioblastoma of the brain, 55 lung cancer metastases and 103 breast cancer metastases. Segmentation of the regions of interest was performed semi-automatically in the free 3D-Slicer software with the ability to upload radiomic features from the regions of interest. For each lesion, 107 radiomic features were calculated from T1 and T2 sequences. Statistics: The calculation of statistical indicators was performed in a computer program for statistical data processing IBMSPSS Statistics 23. In statistical data processing, the Mann-Whitney statistical criterion for quantitative indicators and correlation analysis using the Pearson criterion were used to reduce the feature space. The reduction of the feature space and the selection of predictors by the feature_importances measure based on decision forests were carried out. Machine learning models were built in Python 3.10 using specialized libraries.RESULTS: For the model based on radiomic features extracted from T1 sequence, random forest showed the most efficient result, ROC-AUC=0.815 [0.749; 0.874]. For the model based on the radiomic features extracted from the T2 sequence, random forest showed the most effective result, ROC-AUC=0.817 [0.743; 0.873]. For the complex model based on radiomic features extracted from T1 and T2 sequences, random forest showed the most efficient result, ROC-AUC=0.855 [0.789; 0.906].DISCUSSION: The classification models and their metrics obtained by us indicate that the radiomic features extracted from T2 weighted MR images make it possible to differentiate breast cancer metastases from lung cancer metastases with higher sensitivity than the features extracted from T1 weighted MR images. We also identified a large number of significantly different indicators in the construction of models for the differentiation of glioblastomas from metastases, which demonstrates the prospects of this direction. It is planned to continue the study with the expansion of samples. Our conclusions are also confirmed by the research results of our foreign colleagues.CONCLUSION: The models we have obtained are highly accurate and sensitive to the differentiation of metastases of various etiologies and demonstrate significant potential in continuing this study with an expansion of samples.

Machine Learning Reveals Microbial Taxa Associated with a Swim across the Pacific Ocean.

Purpose: This study aimed to characterize the association between microbial dynamics and excessive exercise. Methods: Swabbed fecal samples, body composition (percent body fat), and swimming logs were collected (n = 94) from a single individual over 107 days as he swam across the Pacific Ocean. The V4 region of the 16S rRNA gene was sequenced, generating 6.2 million amplicon sequence variants. Multivariate analysis was used to analyze the microbial community structure, and machine learning (random forest) was used to model the microbial dynamics over time using R statistical programming. Results: Our findings show a significant reduction in percent fat mass (Pearson; p < 0.01, R = -0.89) and daily swim distance (Spearman; p < 0.01, R = -0.30). Furthermore, the microbial community structure became increasingly similar over time (PERMANOVA; p < 0.01, R = -0.27). Decision-based modeling (random forest) revealed the genera Alistipes, Anaerostipes, Bifidobacterium, Butyricimonas, Lachnospira, Lachnobacterium, and Ruminococcus as important microbial biomarkers of excessive exercise for explaining variations observed throughout the swim (OOB; R = 0.893). Conclusions: We show that microbial community structure and composition accurately classify outcomes of excessive exercise in relation to body composition, blood pressure, and daily swim distance. More importantly, microbial dynamics reveal the microbial taxa significantly associated with increased exercise volume, highlighting specific microbes responsive to excessive swimming.

Bibliometric Analysis on of the Impact of Screening to Minimize Maternal Mental Health on Neonatal Outcomes: A Systematic Review.

(1) Background: Prenatal depression, maternal anxiety, puerperal psychosis, and suicidal thoughts affect child welfare and development and maternal health and mortality. Women in low-income countries suffer maternal mental health issues in 25% of cases during pregnancy and 20% of cases thereafter. However, MMH screening, diagnosis, and reporting are lacking. The primary goals of the present study are twofold, as follows: firstly, to evaluate the importance of screening maternal mental health to alleviate perinatal depression and maternal anxiety, and, secondly, to analyze research patterns and propose novel approaches and procedures to bridge the current research gap and aid practitioners in enhancing the quality of care offered to women exhibiting symptoms of perinatal depression. (2) Methods: We conducted a bibliometric analysis to analyze the research topic, using the bibliometric tools Biblioshiny and VOSviewer, as well as the R statistical programming language. To accomplish our goal, we obtained a total of 243 documents from the Scopus and PubMed databases and conducted an analysis utilizing network, co-occurrence, and multiple correlation approaches. (3) Results: Most of the publications in the field were published between the years 2021 and 2024. The results of this study highlight the significance of shifting from conventional screening methods to digital ones for healthcare professionals to effectively manage the symptoms of maternal mental health associated with postpartum depression. Furthermore, the results of the present study suggest that digital screening can prevent maternal physical morbidity, contribute to psychosocial functioning, and enhance infant physical and cognitive health. (4) Conclusions: The research indicates that it is crucial to adopt and include a computerized screening practice to efficiently and immediately detect and clarify the signs of prenatal to neonatal depression. The introduction of digital screening has led to a decrease in scoring errors, an improvement in screening effectiveness, a decrease in administration times, the creation of clinical and patient reports, and the initiation of referrals for anxiety and depression therapy.