Statistical Correlation Research Articles

Long-term evolution of binary orbits induced by circumbinary disks

Circumbinary disks are found in a variety of astrophysical scenarios, spanning binary star formation to accreting supermassive black hole binaries. Depending on the characteristics of the system, the interaction with a circumbinary disk can either damp or excite the binary’s eccentricity and can also widen or shrink the orbit. To predict the outcome of the long-term disk-binary interaction, we present a new formalism based on the results of recent suites of hydrodynamic simulations, which resolve the complex geometry of the gas in the vicinity of the binary and fully account for the gravitational and accretion forces. We released a python package, spindler, that implements our model. We show that – under the assumed thin disk model with a fixed thickness and viscosity prescription – accretion onto the binary depletes the disk mass before inducing a significant change in the orbital separation or the mass ratio, unless the mass reservoir feeding the disk is comparable to the mass of the binary. This finding implies that, in most scenarios, an interaction with a circumbinary disk is not an efficient mechanism to shrink the orbit of the binary. However, the interaction can excite the eccentricity up to an equilibrium value, and induce a statistical correlation between the mass ratio and eccentricity, as long as the mass of the disk is at least a few percent of the mass of the binary. We consider the applicability of our model to a variety of astrophysical scenarios: during star formation, in evolved stellar binaries, triples, and in supermassive black hole binaries. We discuss the theoretical and observational implications of our predictions.

The Impact of Thyroid Surgery on Calcium and Magnesium Homeostasis: A Prospective Study.

Total thyroidectomy constitutes one of the bread-and-butter procedures of surgeons all over the world. Like with any surgical procedure, complications form a part and parcel of the postoperative course in the hospital. Hypocalcemia represents one such prevalent complication post-total thyroidectomy. This study aimed to evaluate the impact of total thyroidectomy on calcium and magnesium levels and to assess the role of magnesium in postoperative hypocalcemia. This study was carried out at a tertiary health center over a two-year period from 2022 to 2024. It involved 100 participants with thyroid conditions (benign/malignant) who required total thyroidectomy. Patients with pre-existing conditions affecting calcium levels (e.g., chronic renal failure, medullary carcinoma thyroid, etc.) were expressly excluded.Preoperative calcium, magnesium, and parathyroid hormone (PTH) levels were recorded. Intraoperative parameters such as time and fluid volume were also measured. Postoperatively, serum calcium and magnesium levels, PTH levels, and complications like hypocalcemia and hypomagnesemia were monitored. The descriptive statistics were computed to delineate the study sample. After completion of data collection, data analysis was achieved using IBM SPSS Statistics for Windows, V. 16.0 (SPSS Inc., Chicago, IL). The chi-squared test of significance was utilized to establish statistical correlations between calcium and magnesium levels post-total thyroidectomy. A p-value of less than 0.05 was considered statistically significant. The study analyzed 100 total thyroidectomy patients. The mean age of patients in our study was 50.7±8.86 years, with 97 females and three males. The most common pathology indicating total thyroidectomy was diffuse colloid goiter (46%), followed by multinodular goiter (38%). Only a single patient had preoperative biochemical hypocalcemia or hypomagnesemia, but none exhibited symptoms. After total thyroidectomy, 15% (n=15) developed hypocalcemia, and 11% (n=11) developed hypomagnesemia. Postoperative mean PTH levels slightly decreased to 28.8±11.75 pg/dl, indicating similar variability to preoperative levels. Patients who underwent intra-capsular dissection had a mean postoperative ionic calcium level of 4.89±0.54 mg/dl, while those who underwent extra-capsular dissection had a slightly lower mean ionic calcium level of 4.72±0.76 mg/dl. Hypocalcemia is one of the most prevalent complications associated with total thyroidectomy. The role of magnesium in maintaining calcium homeostasis after thyroidectomy should be further explored to improve the management of hypocalcemia. Additionally, the type of capsular dissection performed during the surgery can impact the occurrence of hypocalcemia, and using intra-capsular dissection whenever possible may help reduce the incidence of hypocalcemia.

Single nucleotide and copy number variants of cancer driver genes inform drug response in multiple cancers.

Due to the heterogeneity of cancer, precision medicine has been a major challenge for cancer treatment. Determining medication regimens based on patient genotypes has become a research hotspot in cancer genomics. In this study, we aim to identify key biomarkers for targeted therapies based on single nucleotide variants (SNVs) and copy number variants (CNVs) of genes. The experiment is carried out on 7 cancers on the Encyclopedia of Cancer Cell Lines (CCLE) dataset. Considering the high mutability of driver genes which result in abundant mutated samples, the effect of data sparsity can be eliminated to a large extent. Therefore, we focus on discovering the relationship between driver mutation patterns and three measures of drug response, namely area under the curve (AUC), half maximal effective concentration (EC50), and log2-fold change (LFC). First, multiple statistical methods are applied to assess the significance of difference in drug response between sample groups. Next, for each driver gene, we analyze the extent to which its mutations can affect drug response. Based on the results of multiple hypothesis tests and correlation analyses, our main findings include the validation of several known drug response biomarkers such as BRAF, NRAS, MAP2K1, MAP2K2, and CDKN2A, as well as genes with huge potential to infer drug responses. It is worth emphasizing that we identify a list of genes including SALL4, B2M, BAP1, CCDC6, ERBB4, FOXA1, GRIN2A, and PTPRT, whose impact on drug response spans multiple cancers and should be prioritized as key biomarkers for targeted therapies. Furthermore, based on the statistical p-values and correlation coefficients, we construct gene-drug sensitivity maps for cancer drug recommendation. In this work, we show that driver mutation patterns could be used to tailor therapeutics for precision medicine.

이주배경 독거청년노동자의 한국생활만족도에 영향을 미치는 요인분석

The purpose of this study is to examine factors that affect the satisfaction with life in Korea among young migrant workers living alone. To do this, this study used the 2022 Survey on Immigrant’s Living Conditions and Labour Force data conducted by Statistics Korea and Ministry of Justice. The sample consisted of 2,138 young migrant worker living alone between the ages of 15 and 39. The data were subjected to descriptive statistical analysis, T-test, one-way ANOVA, correlation analysis and hierarchical regression analysis using the SPSS 26.0 statistical program. The main results of this study are as follows: First, satisfaction with life in Korea was correlated with Korean language proficiency level, subjective health status, discrimination experience, and crisis helper. Second, ultimately factors affecting life satisfaction in Korea included subjective health status, experience discrimination, and crisis helper, excluding Korean language proficiency level. Based on those study results, this study discussed practical and policy implications for enhancing the satisfaction with life in Korea among young migrant workers living alone.

REMEDIAL PRACTICES AND STUDENTS COMPETENCES IN MATHEMATICS IN PUBLIC SECONDARY SCHOOLS IN RWANDA A CASE OF GICUMBI DISTRICT

Background: Mathematics plays a crucial role in both vocational success (Jetter, 2017) and everyday life (Umameh, 2011), yet many students face challenges in mastering it. Globally, educational equity remains a priority, with persistent disparities in math education, especially among low-SES students (UNESCO, OECD). Tanzania and Rwanda are actively addressing these challenges to enhance educational outcomes. Materials and Methods: This descriptive survey study involved 171 participants from 32 secondary schools in Gicumbi District: 105 mathematics instructors, 50 subject leaders, 35 head teachers, and 110 students. Data collection employed random sampling, with Slovenes method used to select the study sample. SPSS version 21.0 facilitated analysis, encompassing descriptive statistics (frequency, percentage, mean, standard deviation) and inferential statistics (correlation, regression coefficients). Results and Discussions: Findings revealed strong consensus among respondents on the efficacy of modifying instructional methods (80.0%), using personalized learning materials (63.1%), integrating visual and auditory resources (60.0%), and creating tailored exercises (68.0%) to improve math competencies. Key indicators such as problem-solving (64.3%), method application (96.6%), reasoning (92.3%), and mathematical representation (92.3%) demonstrated significant improvements. Enhanced physical facilities also correlated positively with student outcomes, underscoring the role of supportive environments in fostering mathematical competence. Conclusion: The study emphasizes the effectiveness of adapting teaching methods and environments to enhance students math skills. Customized approaches, including personalized materials and multimedia integration, proved instrumental in improving competencies like problem-solving and reasoning. Statistical analyses consistently supported these findings, highlighting the importance of personalized and diversified teaching strategies in enhancing math education in Gicumbi, Rwanda.

The utility of the child development review in Suriname: Validating a neurodevelopmental screener for use in a low- to middle- income Country

BackgroundAccess to efficient, culturally relevant, and validated measures of neurodevelopment in Low- and Middle-Income Countries (LMICs) remains a critical need. This study describes the validation and reliability of the Child Development Review (CDR), a parent report neurodevelopmental screening tool, for use in a cohort of Surinamese children aged 2–4 years. SubjectsComplete data from 355 Surinamese children through the Caribbean Consortium for Research in Environmental and Occupational Health were utilized for validation. Convergent validity was assessed using a subset of 31 children with concurrently administered CDRs and Bayley Scales of Infant and Child Development Third Edition (BSID-III). MethodsCronbach's alpha was used to assess subscale reliability. Cluster analyses were used to assess internal factor structure. Measures of convergent validity used Cohen's Kappa statistic and partial correlations between comparative CDR and BSID-III subscales. ResultsCronbach's Alpha values were acceptable for all CDR subscales (range 0.63 - 0.79). CDR subscale responses clustered into two distinct groups, representing milestones that were or were not achieved. Patterns of change indicate increased milestone achievement with increased age. Partial correlations indicated that the social, fine motor, and language subscales of the CDR and BSID-III subscales were significantly correlated. However, Cohen's Kappa was only significant for the gross motor CDR and BSID-III subscales. ConclusionsThe CDR has acceptable reliability, internal validity, and convergent validity. Use of the CDR should be considered as a screening tool for neurodevelopment in Suriname and may provide an efficient initial assessment of developmental delay in LMIC.

The technological revolution’s impact on business management

The rapid advancement of technology in the era of the fourth industrial revolution has significantly transformed organizational management practices. This study examines the influence of technological progress on organizational management, specifically analyzing the effects of data analysis and digital management methods in response to these changes. The main objective is to determine how these technological advancements impact enterprises of various sizes in the Czech Republic. The research employed comparative and analytical approaches, utilizing survey data collected from numerous organizations. Concrete methods used in the study include a comprehensive questionnaire survey, comparative analysis, and statistical correlation analysis to assess the significance of technologies based on the classification of enterprise size. The findings demonstrate substantial disparities in the implementation and advantages of technology contingent upon the magnitude of the organization, with smaller and larger enterprises exhibiting enhanced flexibility and deliberate assimilation of novel technologies. The main conclusion is that proficient administration of technology results in competitive advantages and operational efficiencies. Companies are advised to customize their technology strategies based on their available resources and market requirements. Further analysis explores the connections between investments in technology and other organizational elements such as financial resources and personnel, highlighting the importance of developing coherent plans that successfully incorporate technology into the overall structure of the organization.

A Correlational Analysis of Perceived Benefits of Exercise Participation with Executive Functioning Behaviors

Physical activity and exercise regularly can help you stay healthy, energetic, and independent as you age. Exercise is essential in the prevention of health problems such as stroke. Many studies have demonstrated the health advantages of regular exercise. Physical activity is defined as any bodily movement requiring energy expenditure produced by skeletal muscles. The terms “physical activity” and “exercise” are not synonymous. Exercise is a type of systematic, repeated, and deliberate physical exercise. “A sound body has a sound mind,” which suggests that if a person is weak, dull, or unwell, he will be unable to do his task properly and promptly. It is critical to have a clear mind before beginning any work, whether it is office work, study, or creative work [28]. As a contribution to the existing studies made, this research determined the extent of the significant relationship in terms of the perceived benefits of exercise participation and executive functioning behaviors of the Tertiary students. Specifically, researchers hypothesized that there is a significant relationship between the perceived benefits of exercise participation and executive functioning behaviors of Tertiary students. The researchers utilized a descriptive statistic and bivariate correlation coefficient also known as the Pearson correlation coefficient (or the Pearson r) to analyze the quantitative data collected to figure out the relationship between perceived benefits of exercise participation and executive functioning behaviors of the 3rd Year Tertiary students. One hundred ninety-three (193) students coming from the 3rd Year Tertiary Department were selected as the respondents of the study. The researchers used an online platform (Google Forms) to float the standardized survey questionnaires after debriefing the respondents. Participants were asked to answer two scales measuring the variables of interest wherein the scales are The Exercise Benefit Scale and the Executive Skills Questionnaire. The study found that there is a significant relationship between perceived benefits of exercise participation and executive functioning behaviors of the 3rd Year Tertiary students (r = .621; p = .00). It is vital to emphasize that exercising enhances a child’s self-esteem, social and emotional interactions in a group, and comprehensive knowledge about the world. Exercise approaches, dance, and relaxation learning may all aid in the development of a student’s executive behavior, which is why they should be incorporated into today’s education.

Global value chains and their impact on Ukraine’s agro-industrial complex

In the contemporary global economic environment, integration into global value chains is a crucial factor for a country’s economic growth. The aim of this research was to determine the impact of Ukraine’s participation in global value chains on the country’s agro-industrial complex. The study employed statistical analysis, regression analysis, econometric modelling, correlation analysis, and analysis of indices of a country’s participation and position in global value chains. It was established that during 2010-2011, the Ukrainian economy demonstrated high growth rates of gross domestic product and exports due to the growth of foreign value-added. Starting in 2012, growth rates began to decline due to economic crises, political instability, and the war that began in 2014. The COVID-19 pandemic also had a negative impact on the economic situation in 2020. Despite the full-scale war in 2022, a slow economic recovery was observed in 2023, driven by an increase in foreign gross value-added in exports. Regression analysis showed a strong correlation between Ukraine’s gross domestic product and indicators of foreign investment in exports and total exports. It was found that an increase in foreign gross value-added in exports has a negative impact on gross domestic product, while an increase in total exports has a positive impact on economic growth. Despite the complexity of the global value chain system, the results indicate Ukraine’s potential for further integration into global economic processes. It has been found that the agricultural sector is also affected by fluctuations in foreign gross value-added, which is reflected in the productivity and export capabilities of the agricultural sector. An analysis of the participation of key industries, including the agro-industrial complex, in GVCparticipation has shown a trend towards a decrease in the share of foreign value-added in the gross export of industrial products, indicating an increase in domestic value-added. The research results can be used to develop an effective strategy for Ukraine’s economic development by optimising participation in global value chains and reducing dependence on foreign value-added in exports

A new technique for percutaneous screw fixation for treating FFP IIIa and IIIb fragility fractures of the pelvis

To determine the presence of a consistent osseous corridor from the lateral-posterior aspect of the anterior inferior iliac spine to the sacral wing that could be used for safe trans percutaneous screw fixation for pelvic fragility fractures of the iliac wing and fracture dislocations of the sacroiliac joint (FFP types IIIa and IIIb). Computed tomography (CT) scans were obtained from 100 patients and imported to Mimics software for 3D reconstruction. Then, a cylinder was drawn to imitate the modified LC-II screw and adjusted to a maximum radius and length to obtain the feasible region. Thirteen parameters of the osseous corridor of the modified LC-II screw were measured. Differences between sex groups were compared, and significant statistical correlations were carefully studied to determine potentially important clinical relationships. The records of patients with FFP type IIIa and IIIb fragility fractures of the pelvis were extracted from our hospital. Patients who underwent modified LC-II screw fixation, LC-II screw fixation or reconstruction plate fixation were included. Patients’ operative characteristics and complications were recorded at follow-up. Fracture reduction quality was assessed using the Matta standard. Functional outcomes were evaluated using the Majeed grading system. The mean maximum diameters of the osseous corridors of the modified LC-II screw in males and females were 12.73 and 10.83 mm, respectively. The mean maximum lengths of the osseous corridors of the modified LC-II screw in males and females were 96.37 and 93.37 mm, respectively. In the treatment of patients with FFP IIIa and FFP IIIb fractures, the group of treatment by the modified LC-II screws fixation was shown significantly shorter operative time and fewer intraoperative blood loss in comparison to that by the reconstruction plates. In the present study, all the males and females had a complete osseous corridor of the modified LC-II screw. The clinical results of the patients who were treated with modified LC-II screw fixation suggest that the novel method has a good preliminary outcome.

Distribution of and Relationships between Epidemiological and Clinicopathological Parameters in Canine Leishmaniosis: A Retrospective Study of 15 Years (2009-2023).

Leishmaniosis is a vector-borne disease caused by protozoan parasites of the genus Leishmania, which are zoonotic and have an important impact on animal and public health globally. Between 2009 and 2023, blood samples from domestic dogs with clinical suspicion of leishmaniosis were received from 286 veterinary medical centres throughout mainland Portugal. An enzyme-linked immunosorbent assay (ELISA) was utilised to detect antibodies against Leishmania infantum antigens. Additionally, a complete blood count and tests for total proteins, urea, creatinine and alanine aminotransferase, as well as protein electrophoresis, were also performed. No significant relationship between sex and breed was observed. The age distribution was bimodal, with the highest prevalence of disease occurring at 2-5 years of age and a secondary peak occurring at 6 years or over (p < 0.001). No statistical correlation was observed between creatinine and urea across the ELISA serological groups. In contrast, both the gamma globulin levels (r = 0.45; p < 0.001) and the albumin/globulin ratio (r = -0.36; p < 0.001) exhibited moderate correlations with the ELISA. These findings support recent seroprevalence studies in dogs, with some geographical areas in Northern Portugal exhibiting the highest values, which may be the result of geographical shifts in parasite circulation due to climate change.

Hematological indices: potential markers of disease activity in ankylosing spondylitis patients treated with biological drugs

BackgroundSome important hematological indices implement acute phase reactions. They can be used to assess disease activity and therapeutic response in many inflammatory conditions. This work aimed to determine whether different hematological indices can be used to assess disease activity and therapeutic response in patients with ankylosing spondylitis (AS) on biological drugs.Patients and methodsNinety-seven AS patients and a similar number of controls were involved in the current study. The Ankylosing Spondylitis Disease Activity Score (ASDAS) was used to assess the disease activity. Different complete blood count parameters and indices were assessed.ResultsThere was a significant difference between the patients and controls as regards mean corpuscular volume, mean corpuscular hemoglobin, red blood cells count, red cell distribution width, mean platelet volume, platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII). Moreover, there was a statistical correlation between ASDAS on one side and hemoglobin (Hb), hematocrit (HTC), lymphocyte count, neutrophil-to-lymphocyte ratio (NLR), PLR, and SII on the other side. When the patient group was divided into 2 subgroups according to ASDAS, with patients with inactive and low disease activity in one subgroup and those with very high and high disease activity in another subgroup, there was a significant difference as regards Hb, HTC, mean corpuscular hemoglobin concentration, NLR, PLR, SII, and also ESR and CRP levels. Moreover, there was a significant correlation between PLR and SII levels on one side and ESR on the other side.ConclusionHematological indices such as PLR, NLR, and SII might be potential markers for follow-up of disease activity and therapeutic response in AS patients treated with biological therapy. This emphasizes the significance of a comprehensive approach for AS patient assessment and follow-up of therapeutic drugs, considering inflammatory markers, hematological indices, and disease activity scores.

Hubungan Indeks Massa Tubuh Terhadap Kelincahan Pemain Futsal Academy Al-Hadid Surabaya Usia 20 Tahun

The dominant characteristics of movement in futsal are fast and agile in changing direction of movement, which is explained as agility. To maximize the physical components of agility, an ideal body composition will certainly be needed, which can be seen through the body mass index. Body mass index is a measuring tool to determine a person's ideal body composition through the calculation of weight and height. This study investigates the relationship between body mass index and agility of futsal players at the AL-Hadid Academy Surabaya aged 20 years in 2024. This study uses a quantitative descriptive approach that focuses on correlation. The data collection method is carried out using 2 instruments, including measuring height and weight to calculate body mass index with the formula and conducting an agility test using the illinois agility test which is only measured once on each instrument. Body mass index is the independent variable in this study, and agility is the dependent variable. using descriptive statistical data analysis methods, linearity tests, and product moment correlation analysis. The results of data analysis show that body mass index has a linear relationship in the linearity test with a significant deviation form linearity value of 0.165&gt; 0.05. Then in the product moment correlation test, a significance value of 0.000 and a correlation coefficient value of 0.709 were obtained, which can be said to be correlated, the direction of the relationship is positive, and indicates a very strong degree of relationship. Based on the statistical results, it can be concluded that body mass index has a very strong relationship to the agility of futsal players.

Seismic performance and damage assessment of bridges during the 2023 Kahramanmaras, Türkiye earthquakes (Mw = 7.8, Mw = 7.6)

This article presents a summary of the damage observed in bridges in the regions affected by the 6 February 2023 Kahramanmaras, Türkiye earthquake sequence. A bridge database was developed based on the observations from multiple reconnaissance groups that visited the bridges. These reconnaissance groups collectively visited 140 individual bridges that were subjected to various intensities of ground shaking. The severity of the observed damage ranged from no damage to total collapse. The types of damage to bridge components mainly included cracking and shifting of abutments, failure of pier cap shear blocks, shifting or dislodging of bearing pads, cracking of girders and loss of prestress, plastic hinging at pier bases, residual pier drift, and distress to deck surfaces, handrails, and carried utilities. Recorded and estimated seismic intensity measures are presented for each bridge site, and statistical information and correlations were developed considering the intensity of shaking, bridge parameters, and observed damage. Observations from a few visited sites are presented as case studies to illustrate the common failure mechanisms. The bridge database and presented results are expected to serve as a reference for further analysis, such as statistical verification, correlation, or damage estimations, and discussion regarding the mitigation of the observed vulnerabilities of bridges in Türkiye and those with similar construction worldwide.

Dance Creation Based on the Development and Application of a Computer Three-Dimensional Auxiliary System

A three-dimensional auxiliary system serves as a foundational framework for spatial analysis and modeling in various fields. This system serves as a fundamental tool for visualizing and manipulating three-dimensional data, allowing researchers, designers, and engineers to accurately represent and analyze complex structures and environments. Dance creation is a multifaceted artistic process that involves choreographing movements, sequences, and gestures to convey ideas, emotions, and narratives through bodily expression. This paper uses the advanced automated application model for the dance creation with the 3D-auxiliary system for the choreography. The constructed model incorporates statistically integrated Principal Component Analysis (PCA) for the computation of features in the dance creation movement prediction. Finally, the estimation of the statistically integrated PCA model is applied over neural network modeling for the classification of features in the dance creation. With the estimated PCA model values statistical correlation between the PCA features are estimated and classified for the different dance types. The examination is based on the classification of dance movement dynamics, patterns, and stylistic elements for the dance creation. Simulation estimation demonstrated that a constructed statistical 3D auxiliary system was effectively involved in the dance movement prediction with the classification of features through a neural network for the dance movement prediction. The PCA model uses the 5 features to evaluate the auxiliary points of the dance movement in the reference human video. Through the analysis of the PCA features with the statistical values the outline sketch of the dance is framed and dance movement are created.

Comparability analysis of the HNT-1P Huvitz non contact tonometer for the measurement of intraocular pressure.

To evaluate the diagnostic validity of the HNT-1P non-contact tonometer (Huvitz) as a tool for accurately measuring intraocular pressure (IOP) in patients with healthy eyes, compared to the Goldmann applanation tonometer (GAT), which is the Gold Standard method for measurement of IOP. Observational, descriptive, transversal study using 148 eyes of 74 healthy patients without a diagnosis of glaucoma or other ophthalmological diseases. Three measurements of IOP were taken in each eye, using three tonometers: HNT-1P, ICR100, and GAT. The median IOP (quartiles) and mean IOP (SD) its statistical significance were calculated, and comparisons were made between the mean and median IOP values found in three groups: GAT-HNT, GAT-ICR, and HNT-ICR. The difference in mean and median IOP was analyzed in each of the three study groups, and its statistical significance and concordance correlation coefficient (CCC) were calculated. The median IOP with HNT-1P was statistically significantly lower than the median IOP with GAT, (1.1 mmHg, p < 0.001). The median IOP with HNT-1P was also lower than the median IOP with ICR100. As an additional result, the median IOP with GAT was lower than the median IOP with ICR. The CCC was moderate for HNT-ICR (0.72) and low for GAT-HNT and GAT-ICR (0.43 and 0.38, respectively). HNT-1P (Huvitz) provides statistically significantly lower IOP values than those obtained with GAT. HNT-1P could be used for screening of ocular hypertension in postoperative patients. The IOP measurement obtained with HNT-1P should be confirmed with GAT. HNT-1P yields lower IOP values than those obtained with ICR.

HNCGAT: a method for predicting plant metabolite-protein interaction using heterogeneous neighbor contrastive graph attention network.

The prediction of metabolite-protein interactions (MPIs) plays an important role in plant basic life functions. Compared with the traditional experimental methods and the high-throughput genomics methods using statistical correlation, applying heterogeneous graph neural networks to the prediction of MPIs in plants can reduce the cost of manpower, resources, and time. However, to the best of our knowledge, applying heterogeneous graph neural networks to the prediction of MPIs in plants still remains under-explored. In this work, we propose a novel model named heterogeneous neighbor contrastive graph attention network (HNCGAT), for the prediction of MPIs in Arabidopsis. The HNCGAT employs the type-specific attention-based neighborhood aggregation mechanism to learn node embeddings of proteins, metabolites, and functional-annotations, and designs a novel heterogeneous neighbor contrastive learning framework to preserve heterogeneous network topological structures. Extensive experimental results and ablation study demonstrate the effectiveness of the HNCGAT model for MPI prediction. In addition, a case study on our MPI prediction results supports that the HNCGAT model can effectively predict the potential MPIs in plant.

The role of the media in the formation of national (ethnic) identity

The public beliefs are formed under the significant influence of the media. Such an influence can have both positive consequences, in particular, strengthened national identity, and negative consequences — the sowing of enmity, doubts, the destruction of authority. Therefore, the aim of this study is to analyze the role of the media in the formation of national identity in terms of three components: the provision of information by the media, the reaction of citizens and state initiatives. The study employed statistical analysis, survey results, correlation analysis, and content analysis. The current state of the national (ethnic) identity of Ukrainians was described in the research, its significant growth during the period of independence (up to 84.6% in 2022) was noted. The role of the media in the formation of national identity was analysed according to the three identified vectors of influence. The academic novelty of this study is the approach to analysing the role of the media in the formation of national identity in terms of three components: information provided by the media; citizens’ reaction to this information; state initiatives that mediate the relationship between the media and society.

Detection of Trichomonas vaginalis by microscopy and molecular methods in women referred to health centers in Tabriz, Northwest Iran.

Trichomoniasis is a parasitic disease that affects the human reproductive and urinary systems, representing a substantial non-viral sexually transmitted infection worldwide. Given its impact on reproductive health, and the limited available information on the prevalence of Trichomonas vaginalis, this study aimed to evaluate the prevalence of T. vaginalis among women referred to health centers in Tabriz, Northwest Iran. Study was conducted on 448 suspicious women who attended to 29Bahman hospital in Tabriz, Northwest Iran, during September 2020 to September 2021. Demographic data were collected according to the study protocol. Vaginal discharges were obtained using sterile swabs, and the prevalence of T. vaginalis was determined using Papanicolauo staining and PCR method. Among the 448 cases studied, 48 (10.7%) samples were suspected as a T. vaginalis infection, while 4 (0.89%) confirmed using the PCR method. The mean age of infected individuals was 41.7 ± 9.4 years. No statistical correlation was observed between inflammation, method of contraception and infection (p = 0.8). The present study revealed a relatively low prevalence of T. vaginalis infection within the study population. Additionally, the utilization of the PCR method can be beneficial in confirming suspected samples.

Investigating the effect of fuel properties and environmental parameters on low-octane gasoline-like fuel spray combustion and emissions using machine learning-global sensitivity analysis method

The gasoline compression ignition mode is an advanced combustion mode that achieves high efficiency with low emissions. This study constructs a global sensitivity analysis (GSA) by coupling machine learning (ML) algorithms and conducts a comprehensive investigation into the statistical correlations between research octane number (RON), fuel sensitivity (S), three initial ambient parameters, and the spray combustion characteristics of gasoline-like fuels. Eighty sets of CFD numerical simulation data were used for training the machine learning model. Results show liquid length (LL) is most sensitive to changes in ambient pressure while ambient temperature significantly influences vapor penetration length (VPL). Regarding combustion behaviors, ignition delay (ID) and flame lift-off length (LOL) show the highest sensitivity to ambient temperature. The occurrence of distinct ignition points in the domain also advances from 1.75 ms to 0.42 ms as the ambient temperature rises from 1000K to 1200K. Additionally, the ambient temperature has higher-order interaction effects with ambient pressure on LOL. The production of NOx in the field is also more closely correlated with ambient temperature, with higher temperatures promoting its generation. Furthermore, ambient temperature exhibits a positive interaction effect with both ambient pressure and oxygen concentration on NOx emissions.