Nature Of State Research Articles

Literature review and preliminary analysis of cassava by-products potential use in particleboards

Particle panels for construction are environmentally favorable, as they allow the combination of different components (as is the case with agro-industrial waste from the production and processing of food and products derived from agricultural activities). The objective of this article is to analyze studies focused on the use of cassava by-products in the production of panels for civil construction/furniture in the last 10 years through a bibliographical survey, as well as to present a preliminary analysis of the feasibility of using cassava by-products to manufacture particle panels in their natural state. As a result, the theoretical search detected the gap created by the scarcity of published studies on the topic. On the other hand, the experimental analysis indicated the promising potential of using the cassava by-product for panel production, provided that the weaknesses initially indicated in this research can be addressed.

De Novo Atomistic Discovery of Disordered Mechanical Metamaterials by Machine Learning.

Architected materials design across orders of magnitude length scale intrigues exceptional mechanical responses nonexistent in their natural bulk state. However, the so-termed mechanical metamaterials, when scaling bottom down to the atomistic or microparticle level, remain largely unexplored and conventionally fall out of their coarse-resolution, ordered-pattern design space. Here, combining high-throughput molecular dynamics (MD) simulations and machine learning (ML) strategies, some intriguing atomistic families of disordered mechanical metamaterials are discovered, as fabricated by melt quenching and exemplified herein by lightweight-yet-stiff cellular materials featuring a theoretical limit of linear stiffness-density scaling, whose structural disorder-rather than order-is key to reduce the scaling exponent and is simply controlled by the bonding interactions and their directionality that enable flexible tunability experimentally. Importantly, a systematic navigation in the forcefield landscape reveals that, in-between directional and non-directional bonding such as covalent and ionic bonds, modest bond directionality is most likely to promotes disordered packing of polyhedral, stretching-dominated structures responsible for the formation of metamaterials. This work pioneers a bottom-down atomistic scheme to design mechanical metamaterials formatted disorderly, unlocking a largely untapped field in leveraging structural disorder in devising metamaterials atomistically and, potentially, generic to conventional upscaled designs.

Profesionalisme Guru dalam Pengembangan Mutu Pendidikan di Era Milenial

This article aims to discuss teacher professionalism in developing the quality of education in the millennial era. This research is a field research study, in which the preparation of data is carried out in the field to make observations of phenomena in a natural state. Data collection techniques use field observation, interview, and documentation methods. The data analysis method is to use stages starting from data refining, data reduction, data presentation, and conclusion. Test the validity of data through credibility tests, transferability tests, dependability tests, and comformability tests. The results of the data analysis show that teacher professionalism is an effort made to improve the level or degree of a teacher's profession concerning teacher abilities, both mastery of teaching material or mastery of teaching methodology, as well as teacher professional attitudes regarding teacher motivation and commitment in carrying out duties as teachers. Teachers must develop their profession in accordance with the quality of education in this millennial era which provides flexibility for teachers to be able to freely choose, create, use, and develop their learning

Impacts, Potential Benefits and Eradication Feasibility of Aquatic Alien Species in an Integral Natural State Reserve.

Riverine wetlands are stepping-stone environments for the protection of local biodiversity, but they are particularly vulnerable to biological invasions. In order to take action against biological invasions, it is crucial to assess the impacts of alien species. However, it is also important to assess the potential benefits on ecosystem services that alien species could have. Once it has been verified that negative impacts are higher than potential benefits, it is important to propose feasible actions to contrast them. In this study, we assessed eight freshwater alien species recorded in an integral protected wetland using the Invasive Species Effects Assessment Tool (INSEAT) to quantify their negative impacts and potential benefits on ecosystem services. Moreover, for each species, we evaluated the feasibility of the main eradication techniques currently proposed in the literature using the Non-Native Risk Management scheme (NNRM), with the final aim of suggesting effective actions for their management. The INSEAT results indicated that all the assessed species had more impacts than benefits while NNRM provided useful indications on the best practical conservation actions to use for reducing the density, and therefore, the negative impacts on ecosystem services and the local biodiversity of the assessed alien species.

Use of immuno-flow cytometry and real-time PCR disclose the epidemiological behaviour of Erwinia amylovora populations during the winter in Portuguese pear orchards

AbstractThe persistence and progression of Erwinia amylovora in naturally infected orchards is still not fully understood and the majority of studies have been carried out under controlled or artificial infections. A major hurdle stems from the inability to characterize the viability of the bacterium in its natural state. Most standard tests, including real-time qPCR, fail to differentiate live from dead cells, while culture dependent methods lack sensitivity. Even in orchards with recurring infections, the detection of E. amylovora is erratic. Immuno-flow cytometry (IFCM) is considered a high throughput tool in clinics and food industry but has been rarely used as diagnostic test for plant pathogens. Two pear orchards with fire blight history, located in the central part of Portugal, were selected for epidemiological monitoring between February and June, from 2019 to 2022. A total of 440 samples were tested using EPPO standard diagnostic protocols. To address the epidemiological behaviour of E. amylovora, we devised an IFCM test using specific monoclonal antibodies and viability dyes, validated in a subset of 149 samples, testing positive in routine diagnostic tests. Our IFCM test was able to differentiate live and dead E. amylovora in naturally infected samples with concentrations as low as 3.54 × 104 cell·mL−1, confirming positive results for 91% these samples, while 19.4% were considered positive by isolation, 38% using conventional PCR and 95% for real-time qPCR. Temporal analysis showed the highest number of positive samples regardless of the method employed in April, May and June, while viability values measured with IFCM were the highest in April, coinciding with the exit of dormancy and early flowering of pear trees. Integrative analysis of E. amylovora viability and population dynamics over the growing season allowed identification of distinct outbreak risks associated with these Portuguese pear orchards.

Rejection sampling and agent-based models for data limited fisheries

Many of the world’s fisheries are “data-limited” where the information does not allow precise determination of fish stock status and limits the development of appropriate management responses. Two approaches are proposed for use in data-limited stock management strategy evaluations to guide the evaluations and to understand the sources of uncertainty: rejection sampling methods and the incorporation of more complex socio-economic dynamics into management evaluations using agent-based models. In rejection sampling (or rejection filtering) a model is simulated many times with a wide range of priors on parameters and outcomes are compared multiple filtering criteria. Those simulations that pass all the filters form an ensemble of feasible models. The ensemble can be used to look for robust management strategies, robust to both model uncertainties. Agent-based models of fishery economics can be implemented within the rejection framework, integrating the biological and economic understanding of the fishery. A simple artificial example of a difference equation bio-economic model is given to demonstrate the approach. Then rejection sampling is applied to an agent-based model for the hairtail (Trichiurus japonicas) fishery, where an operating model is constructed with rejection/agent-based methods and compared to known data and analyses of the fishery. The usefulness of information and rejection filters are illuminated and efficacy examined. The methods can be helpful for strategic guidance where multiple states of nature are possible as a part of management strategy evaluation.

The influence of the hydrometeorological factors on the CO2 fluxes from the oligotrophic bog surface.

The influence of the hydrometeorological factors on the CO2 fluxes from the oligotrophic bog surface.

Dipolar Spin Ice Regime Proximate to an All-In-All-Out Néel Ground State in the Dipolar-Octupolar Pyrochlore Ce2Sn2O7

The dipolar-octupolar (DO) pyrochlores, R2M2O7 (R=Ce,Sm,Nd), are key players in the search for realizable novel quantum spin liquid (QSL) states as a large parameter space within the DO pyrochlore phase diagram is theorized to host QSL states of both dipolar and octupolar nature. New single crystals and powders of Ce2Sn2O7, synthesized by hydrothermal techniques, present an opportunity for a new characterization of the exchange parameters in Ce2Sn2O7 using the near-neighbor XYZ model Hamiltonian associated with DO pyrochlores. Utilizing quantum numerical linked cluster expansion fits to heat capacity and magnetic susceptibility measurements, and classical Monte Carlo calculations to the diffuse neutron diffraction of the new hydrothermally grown Ce2Sn2O7 samples, we place Ce2Sn2O7’s ground state within the ordered dipolar all-in-all-out (AIAO) Néel phase, with quantum Monte Carlo calculations showing a transition to long-range order at temperatures below those accessed experimentally. Indeed, our new neutron diffraction measurements on the hydrothermally grown Ce2Sn2O7 powders show a broad signal at low scattering wave vectors, reminiscent of a spin ice, in striking contrast from previous powder neutron diffraction on samples grown from solid-state synthesis, which found diffuse scattering at high scattering wave vectors associated with magnetic and suggested an octupolar quantum spin ice state. We conclude that new hydrothermally grown Ce2Sn2O7 samples host a finite-temperature proximate dipolar spin ice phase, above the expected transition to AIAO Néel order. Published by the American Physical Society 2024

Petty's instruments: the Down Survey, territorial natural history and the birth of statistics.

William Petty's work has usually been regarded as an epistemic break in the history of statistical and politico-economic thought. In this paper, I argue that Petty's statistical notions stemmed from the natural-historical techniques he originally implemented to manage the Down Survey. Following Bacon, who viewed the description of trades as a paramount branch of natural history, Petty approached the art of surveying itself as an object of natural-historical analysis. He partitioned the surveying work into individual tasks and implemented a meticulous division of labour, employing hundreds of disbanded soldiers as surveyors and using questionnaires to calibrate the responses of his 'instruments', as he called his specialized workers. By borrowing these methods from natural history to organize surveying work, Petty was able to conceptualize Ireland as a political body defined by tables of aggregate data. I then compare the Down Survey with John Graunt's observations on the bills of mortality to show that both are representative of a particular style of natural history, aimed at describing the natural and political state of a circumscribed territory. I close by considering other manifestations of 'territorial natural history', indicating a continuity between this research tradition and the appearance of statistics in the British Isles.

Effects of restoration years on soil nitrogen and phosphorus in inland salt marshes.

Inland salt marsh wetlands have very important ecological functions in semi-arid areas. However, degradation and soil desertification have impacted these areas, making it necessary to study the impact of wetland restoration years on the soil quality of salt marsh wetland. We used remote sensing methods, field surveys, and inquiries to examine the seasonal profile effects of two-, four-, and six-year restoration periods on total nitrogen (TN), total phosphorus (TP) and the ratio of nitrogen to phosphorus (N:P) in P. australis and S. triqueter wetland natural states. Our results showed that soil TN in P. australis wetland in restored conditions was higher than that in natural conditions. The average soil TP of the S. triqueter wetlands at 0-10 cm, 10-20 cm, 20-30 cm, and 30-40 cm layers was 0.36 g/kg, 0.31 g/kg, 0.21 g/kg, and 0.17 g/kg s in September, respectively. The soil TP of the S.triqueter wetland increased slightly over the entire growing season. The restoration years had a great influence on the soil TP of the S. triqueter wetland from May to July. The soil TN in the P. australis wetland was almost restored to its natural condition in each layer during the six-year restoration period. The soil TP of the S. triqueter wetland was higher in the restored two-year period and showed a decreasing trend with an increased soil depth. Our conclusions can significantly guide the restoration of inland salt marsh wetlands.

Laboratory Liquid-Jet X-ray Microscopy and X-ray Fluorescence Imaging for Biomedical Applications.

Diffraction-limited resolution and low penetration depth are fundamental constraints in optical microscopy and in vivo imaging. Recently, liquid-jet X-ray technology has enabled the generation of X-rays with high-power intensities in laboratory settings. By allowing the observation of cellular processes in their natural state, liquid-jet soft X-ray microscopy (SXM) can provide morphological information on living cells without staining. Furthermore, X-ray fluorescence imaging (XFI) permits the tracking of contrast agents in vivo with high elemental specificity, going beyond attenuation contrast. In this study, we established a methodology to investigate nanoparticle (NP) interactions in vitro and in vivo, solely based on X-ray imaging. We employed soft (0.5 keV) and hard (24 keV) X-rays for cellular studies and preclinical evaluations, respectively. Our results demonstrated the possibility of localizing NPs in the intracellular environment via SXM and evaluating their biodistribution with in vivo multiplexed XFI. We envisage that laboratory liquid-jet X-ray technology will significantly contribute to advancing our understanding of biological systems in the field of nanomedical research.

Mapping adipocyte interactome networks by HaloTag-enrichment-mass spectrometry.

Mapping protein interaction complexes in their natural state in vivo is arguably the Holy Grail of protein network analysis. Detection of protein interaction stoichiometry has been an important technical challenge, as few studies have focused on this. This may, however, be solved by artificial intelligence (AI) and proteomics. Here, we describe the development of HaloTag-based affinity purification mass spectrometry (HaloMS), a high-throughput HaloMS assay for protein interaction discovery. The approach enables the rapid capture of newly expressed proteins, eliminating tedious conventional one-by-one assays. As a proof-of-principle, we used HaloMS to evaluate the protein complex interactions of 17 regulatory proteins in human adipocytes. The adipocyte interactome network was validated using an in vitro pull-down assay and AI-based prediction tools. Applying HaloMS to probe adipocyte differentiation facilitated the identification of previously unknown transcription factor (TF)-protein complexes, revealing proteome-wide human adipocyte TF networks and shedding light on how different pathways are integrated.

Geological detection of hard rocks by GPR and signal time-frequency characteristics analysis in urban underground trenchless construction

Abstract The hard rocks in the stratum can pose safety risks and hinder the progress of urban underground tunnel construction using shield and jacking methods, thereby reducing construction efficiency and increasing construction costs. This paper utilizes wavelet scale energy spectrum, wavelet packet theory and statistical methods to conduct research on the detection of special geological formations such as hard rocks and voids, as well as the analysis of their signal time-frequency characteristics based on the ground-penetrating radar (GPR) technique. On the basis of calibrating the permittivity of different types of rock blocks, we established a forward model for detecting hard rocks and voids, and the simulated signals were analyzed in the time and frequency domains. Subsequently, laboratory experiments were conducted to perform GPR tests on different types of hard rocks in natural and water-saturated states and voids, to explore the time-frequency characteristics, frequency band energy variations, and statistical patterns of typical single-trace signals. The results show that the granite detection signal contains more low-frequency components, the sandstone detection signal contains more medium-low frequency components, while the limestone detection signal contains more medium-high frequency components in their natural state; the signal from the karst cave has relatively more low-frequency components than the signal from the empty cavity. The geometric shape of the rock has no influence on the dominant frequency and time-frequency distribution of its reflection signal. Generally, rocks with higher rebound values (hardness) also exhibit larger variance and standard deviation in frequency band energy. The research has important theoretical significance and practical value for the measurement and assessment of special geological features such as hard rocks and voids in urban underground trenchless construction.

Natural degradation of polypyrrole nanowires in NaOH solutions and its degradation kinetics

The polypyrrole (PPy) nanowires doped with p-toluenesulfonate ions (PPy/pTS NWs) are prepared and degraded in aerated and deaerated NaOH solutions (CNaOH=0.02 - 0.5 M) for different times to examine their natural degradation behavior and kinetics. After degradation, the fluffy PPy/pTS NWs network film generally exhibits a uniform natural degradation state with apparent damaged areas on the nanowires' surface, decreased nanowire diameter, and increased film thickness. The electroactivity degradation of PPy/pTS NWs still follows the first-order degradation kinetics, like the bulk-structured PPy/pTS films. The natural degradation kinetics model established from the bulk-structured PPy films is proven to apply to PPy/pTS NWs. The rate equations for the chemical and electrochemical degradation of PPy/pTS NWs in NaOH solutions are determined. Additionally, it is confirmed that the electrochemical degradation process is the dominant factor, while CNaOH significantly impacts the chemical degradation process. The structural features of PPy/pTS NWs do not alter the chemical and electrochemical degradation processes but significantly accelerate the degradation rates. This research will contribute to our understanding of the degradation kinetics of PPy nanomaterials and support their practical applications.

Beauty and Dao: The Transcendental Expressions of Nature from Emerson’s Prose and the Zhuangzi

As an aesthetic resource in ancient China, the Zhuangzi’s description of Dao is similar to the American philosopher Emerson’s experience of beauty, and both reveal that the essence of beauty lies in its inherent vitality, spiritual transcendence, and the unity of multidimensional connotations. Emerson defines beauty as the constitution of all things in the world and believes it to be an expression of the universe. The Zhuangzi proposes the thought of tiandi damei 天地大美 (lit. Great Beauty of heaven and earth) as a manifestation of the function of the wordless Dao. Nature, intact from any human interference, becomes the common intermediary for Emerson and the Zhuangzi to elaborate on the connotations of beauty. The Emersonian definition of beauty originates from the philosophical implication of the world in ancient Greek, whereas the meaning of Great Beauty in the Zhuangzi, which embodies the worship of heaven in primitive religion, is very close to Emerson’s definition of beauty. The pattern of mei 美 consisting of da 大 (lit. great, equivalent to Dao) and yang 羊 (lit. auspice) signifies the natural celestial phenomena predicting good or bad luck and can be seen as synonymous with Dao illuminated by Daoism. By describing such natural imagery as forest, time sequence, dawn, and wilderness, Emerson reveals the vastness, harmony, brightness, and tranquility of beauty, which not only delights the spirit but also brings the human soul back to its natural state and improves personality. Emerson’s illumination of beauty conforms to those of Dao unraveled by the Zhuangzi. Despite the difference between the former’s poetic linguistic feature and the latter’s application of allegorical fables, both resort to visualized language to express internal aesthetic perceptions of the physical nature. Using the approaches of word tracing, textual comparison, and logical analysis, this article identifies the consistency in the original meanings of beauty in both Emerson’s essays and the Zhuangzi first and then goes on to analyze the similarities between their descriptions of natural imagery, so as to hint at the commonality in their understanding of natural beauty and verify the significance of literary language in cross-cultural comparative research.

Microwave-assisted Natural Gums for Drug Delivery Systems: Recent Progresses and Advances over Emerging Biopolymers and Technologies.

Natural polymers play a crucial role in a wide range of industries, allowing for extensive conjugation with a variety of materials and components to produce a vast multitude of products. Biomaterials have been extensively studied due to their application potential in pharmaceutical formulation development, tissue engineering, and biomedical fields. Despite this, many natural gums in their natural state have limitations in terms of microbial contamination, susceptibility, solubility, and stability. To surmount these limitations, chemical or physical modifications are made to the polymer to tailor its properties to particular applications. These polymer modifications integrate traditional elements of materials science, physics, biology, chemistry, medicine, and engineering. Microwave irradiation has become an established method for accelerating and facilitating chemical modification reactions over the past several decades. This method allows for the efficient execution of synthesis protocols by providing precise temperature and voltage control. In addition, microwave irradiation contributes to sustainable and environmentally friendly chemistry principles. This article highlights the importance of microwave-assisted natural gum modification in the production of novel dosage forms.

Investigating acoustoelasticity of plane elastic waves and second harmonics within isotropic solid media: A novel approach

This paper presents a novel approach to investigating the acoustoelasticity of plane elastic waves and second harmonics within isotropic solid media. The new contributions of this approach consist of providing an intuitive understanding of the essence of acoustoelasticity, offering a more straightforward method to deduce the expressions for acoustic velocities and pre-strains in natural coordinates compared to conventional theory of acoustoelasticity, and introducing a novel methodology for investigating acoustoelasticity of plane elastic waves and second harmonics. The core idea of this approach can be explained as follows: by introducing an intermediate state for describing predeformation between the natural state and the final state, the predefomation can be integrated into the nonlinear wave equation, and acoustoelastic equations of plane elastic waves and second harmonics can be deduced consequently by decomposing this nonlinear wave equation under the second approximation of perturbation theory. When applying this approach to study the acoustoelasticity of P wave and S wave of plane elastic waves, the validity and practicality of this approach are confirmed by contrasting expressions for acoustic velocities and pre-strains in natural coordinates to those found in previous research [8], which exhibit perfect consistency. Furthermore, this paper focuses on the acoustoelasticity of the free second harmonics and the driven second harmonics generated by self-excitation and interaction of plane elastic waves. The results concerning acoustoelasticity can be summarized as follows: firstly, pre-strain only influences wave vectors of plane elastic waves through the speed term in their expressions without altering their amplitudes; secondly, the acoustoelasticity of free second harmonics follows similar rules above; finally, Pre-strain affects the amplitudes and wave vectors of driven second harmonics through the speed terms in their expressions without changing the form of their expressions.

Sialic acid in human milk and infant formulas in China: concentration, distribution and type.

This study compared the concentrations, types and distributions of sialic acid (SA) in human milk at different stages of the postnatal period with those in a range of infant formulas. Breast milk from mothers of healthy, full-term and exclusively breastfed infants was collected on the 2nd (n 246), 7th (n 135), 30th (n 85) and 90th (n 48) day after birth. The SA profiles of human milk, including their distribution, were analysed and compared with twenty-four different infant formulas. Outcome of this observational study was the result of natural exposure. Only SA of type Neu5Ac was detected in human milk. Total SA concentrations were highest in colostrum and reduced significantly over the next 3 months. Approximately 68·7–76·1 % of all SA in human milk were bound to oligosaccharides. Two types of SA, Neu5Ac and Neu5Gc, have been detected in infant formulas. Most SA was present in infant formulas combined with protein. Breastfed infants could receive more SA than formula-fed infants with the same energy intake. Overall, human milk is a preferable source of SA than infant formulas in terms of total SA content, dynamics, distribution and type. These SA profiles in the natural state are worth to be considered by the production of formulas because they may have a great effect on infant nutrition and development.

Application of Prakriti in Understanding the Cause and Role of Treatment in Surgical Diseases

Prakriti can be defined as an individual's natural state, which is determined by their genetic constitution. According to Ayurveda, each person possesses a fixed Prakriti that is established at the moment of conception when the sperm and ovum unite in the womb. The predominance of one, two, or all three Doshas (Vata, Pitta, Kapha) in an individual's constitution dictates their Prakriti. As a result, Prakriti encompasses an individual genetically determined anatomical, physiological and psychological changes. It also influences how a person responds to environmental factors, medications, and their susceptibility to diseases. This concept of Prakriti is one of the earliest principles of preventive and personalized or genomic medicine. In contrast to Prakriti, there is Vikriti, which represents the diseased state of an individual. Understanding one's normal Prakriti is crucial for identifying abnormalities, underscoring its significance in the fields of diagnosis, preventive medicine and therapeutic interventions. Although Prakriti assessment should ideally take place at birth, its influence extends far into an individual's life. Within the realm of Shalya tantra, Prakriti plays a pivotal role. Despite limited literature explicitly addressing the significance of Prakriti in Shalya tantra but understanding and considering the Prakriti when determining treatment is particularly crucial in surgical and parasurgical techniques, as these procedures demand greater Manasika bala.

Human and Society in the Nature State and Civilized State from Hobbes Point of View

The Enlightenment philosophy, particularly the ideas of Thomas Hobbes and his concepts surrounding the State and Society, serves as a philosophical foundation for numerous subsequent discussions in the fields of social and political sciences. Hobbes’ perspective on human nature and his portrayal of the natural state versus civilization are undeniably among the central tenets of modern thought. He characterizes humanity as the ‘wolf-man’ and underscores the necessity of a social contract-based civilized state to ensure security and safeguard collective interests. Hobbes is primarily concerned with peace, and his political framework, rooted in a modern scientific sense, is designed with the explicit goal of establishing and preserving peace. In the natural state, where humanity exists in an uncivilized condition, each individual is self-interested and disconnected, resulting in a landscape fraught with danger and insecurity. However, a glimmer of hope arises from the fact that human awareness of this predicament serves as the very genesis of contemplation and thought directed towards salvation. The cornerstone of security in the natural state is the equality of all individuals within it. According to Hobbes, society does not represent the spontaneous formation of a fundamental condition for collective life but, rather, the conscious regulation of a potentially volatile state perpetually on the brink of conflict. Through surveys, Hobbes asserts that a majority of people within a society willingly delegate their power and authority to an individual or a group, enabling them to consolidate the various wills into a unified collective will through a voting process. This article aims to explore a fundamental shift in ethics as we transition from classical ethics centered around ‘good’ to modern social ethics founded on ‘security’ and ‘stability.’