Start-up Research Articles

Emprendimiento opción para reactivar la economía y el desarrollo sostenible en comuna Santa Elena

El mundo globalizado nos expone día a día ante productos y servicios nuevos, la economía difícil de ciertos segmentos de la población, el auge que en los últimos tiempos ha tomado el concepto de emprendimiento, exige a las universidades el apoyo y el acompañamiento a los habitantes de las comunidades y sectores vulnerables, a fin de hacer realidad las ideas de emprendimiento como una opción para reactivar la economía del sector y, contribuir a enriquecer aspectos personales de los integrantes de la comunidad y mejorar las dinámicas en términos de desarrollo social, económico y ambiental, para ello fue necesario fomentar la generación de ideas de emprendimientos locales, asistirlos en el manejo de los recursos financieros y en la capacitación de personas para la puesta en marcha del negocio, que permita el impulso de la economía del sector; el papel activo en este proceso lo desempeñan los gobiernos locales, pues son ellos los catalizadores de las iniciativas de desarrollo económico local; La metodología utilizada fue de tipo cualitativa y cuantitativa, se aplicó el método inductivo y deductivo y análisis estadístico mediante el análisis de frecuencia y la aplicación de encuestas a las personas que viven en la comunidad de Santa Elena, el objetivo de este trabajo permitió identificar el aporte a la economía de las familias y de la sociedad que generan los emprendimientos, en función de que éste se ha constituido en una herramienta para la reactivación económica en beneficio del desarrollo sostenible del sector, llegando a la conclusión de que el apoyo a través de diferentes ejes es fundamental para que los emprendimientos generen bienestar, comodidad, fuentes de trabajo en el entorno familiar y social y que por ende mejoren las condiciones de vida.

Pressure-driven dynamic simulation of distillation columns in air separation units

At the moment, the change in power generation from fossil energy sources to renewables poses several challenges to the energy system and major energy consumers such as cryogenic air separation plants. Due to a more volatile power generation and the lack of storage systems, the energy price fluctuates and power intensive processes need to adapt regarding their operational agility and flexibility.Currently, air separation units are designed for steady state operation at their optimal operating point with a minimum amount of load change procedures during their lifetime.Within this work, detailed dynamic models of all plant components are developed which are an important tool to get a deeper understanding of flexible plant operations. Based on this, the process design can be adapted to allow for a more flexible mode of operation. In addition, those models can be used to develop and optimise advanced load change control strategies, which are more agile and consume less equipment lifetime compared to the state-of-the-art load change procedures. Hence, air separation plants are able to perform more frequent load changes and participate in a fluctuating energy market. Furthermore, these tasks are particularly challenging for air separation units, since they are mainly characterised by a high degree of process integration, high demands on product purity and non-linear column responses during plant start-up.The “warm” start-up procedure is chosen as a representative scenario for any load change procedure, since it is the numerically most challenging simulation. “Warm” start-up means to initialise the model inventory at ambient conditions with zero flow. Based on this scenario, more technically relevant scenarios like the “cold” start-up after a plant shutdown as well as advanced control strategies can be investigated to allow a more flexible and agile operation.

Design of a fatigue test bench in rotary flexion to evaluate the behavior to cyclical loads

The development of this article shows the process of design, construction and start-up of a fatigue machine in rotary flexion. Fatigue is a subject of considerable relevance and requires adequate equipment for its study, therefore it is sought to contribute to educational and research growth through the development of a functional fatigue machine and where a variety of materials can be studied. The main results were the development of a machine that can carry out a totally inverted stress of 977 Mpa, therefore it can arrive to study steels of high resistance. This machine follows the standards of the normative ASTM E-466 regarding the dimensions of the test specimen. The design of the machine is divided into 3 systems, mechanical system, electrical system and electronic system. When joining these systems obtained a functional and autonomous machine where can make serious and reliable investigations.

Chemogenetics start-up launches

Chemogenetics start-up launches

Insight into start-up, its action and surroundings

Insight into start-up, its action and surroundings

Process Integration Accounting Fouling in Heat Exchanger Network: A Case Study of Crude Oil Distillation Retrofit

This paper presents the approach to predict the future performance of a heat exchanger network based on Pinch retrofit design and detailed historical performance of the unit to improve the operation efficiency, save an energy and increase a throughput. The main input is a finding of a profitable solution of heat exchanger network based on Pinch Analysis, fouling predictive management and a start-up and shut-down time. The approach demonstrates the importance of a dynamic assessment of the retrofit design and operation modes. The case study was developed for crude oil distillation unit with annual capacity of 6 Mt. Dynamic fouling models were built to assist with designing and revamping of heat exchanger network, to reduce the fouling and increase the throughput. Rigorous modelling of refinery heat exchangers network and Pinch Analysis were executed to achieve increased throughput, reduce operation cost and harmful emissions. A new heat exchangers network with improved operation conditions predicting efficient exchanger cleaning schedules under various economic and operational constraints was obtained. The calculations use an HTRI shell-and-tube heat exchanger models, operation data, properties of crude oil and cleaning schedule. Process Integration steps were done by HILECT software and new operation schedule of efficient heat exchangers network was created by HTRI software. The strategy and recommendations for the optimal operation of the retrofitted network were proposed taking into account the economic and process constraints such as exchanger by-passes, operation budget, furnace duty and pumping limit.

Supporting Diverse Challenges of Ageing with Digital Enhanced Living Solutions.

By the 2050, it is estimated that the proportion of people over the age of 80 will have risen from 3.9% to 9.1% of population of Organisation for Economic Cooperation and Development countries. A large proportion of these people will need significant help to manage various chronic illnesses, including dementia, heart disease, diabetes, limited physical movement and many others. Current approaches typically focus on acute episodes of illness and are not well designed to provide adequately for daily living care support. In our rapidly ageing society, a critical need exists for effective, affordable, scalable and safe in-home and in-residential care solutions leveraging a range of current and emerging sensor, interaction and integration technologies. Key aims are to support the ageing to live longer in their own homes; make daily challenges associated with ageing less limiting through use of technology supports; better support carers - both professional and family - in providing monitoring, proactive intervention, and community connectedness; enable in-home and in-residential care organisations to scale their support services and better use their workforces; and ultimately provide better quality of life. Deakin University researchers have been investigating a range of emerging technologies and platforms to realise this vision, which we in broad terms coin Digital Enhanced Living, in the ageing space but also supporting those with anxiety and depression, sleep disorders, various chronic diseases, recovery from injury, and various predictive analytics. A Smart Home solution, carried out in conjunction with a local start-up, has produced and trialled a novel sensor, interaction, and AI-based technology. Virtual Reality (VR) solutions have been used to support carers in the set-up of dementia-friendly homes, in conjunction with Alzheimers Australia. Activity and nutrition solutions, including the use of conversational agents, have been used to build dialogue to engage and change behaviour. Predictive analytics, in conjunction with major hospitals, have been applied to large medical datasets to better support professionals making judgements around discharge outcomes. A set of lessons have been learned from the design, deployment and trialing of these diverse solutions and new development approaches have been crafted to address the challenges faced. In particular, we found that there is a need to consider user emotional expectations as first-class citizens and create methodologies that consider the user needs during the creation of the software solutions. We find that quality and emotional aspects have to be engineered into the solution, rather than added after a technical solution is deployed.

Proceso de paz entre gobierno colombiano y las FARC-EP: camino hacia la reincorporación de combatientes

Los estándares internacionales de Desarme, Desmovilización y Reintegración son recomendaciones hechas por la Organización de las Naciones Unidas para el desarrollo de modelos de reincorporación, que deben ser adaptados de acuerdo a cada contexto. Colombia hoy los aplica en la fase de implementación del acuerdo de paz entre el gobierno nacional y la insurgencia Fuezas Armadas Revolucionarias de Colombia - Ejército del Pueblo, con el objetivo de reincorporar a la vida civil a los excombatientes. De esta manera, el punto dos del acuerdo se enfoca en la participación política y la ampliación democrática, exponiendo la pertinencia de revisar los lineamientos generales pactados en dicho acuerdo para la creación y adecuación de instituciones que se encarguen de acompañar y vigilar la reincorporación política de los excombatientes; así como también de la puesta en marcha del tránsito a la vida, identificando así los retos a los que se enfrentan los excombatientes y las medidas que se deben tomar.

Application of intraoperative MRI and microelectrode recording in deep brain stimulation of subthalamic nucleus for the treatment of Parkinson's disease

Objective To investigate the value of intraoperative MRI (iMRI) and microelectrode recording (MER) in the deep brain stimulation (DBS) of subthalamic nucleus (STN) for the treatment of Parkinson＇s disease. Methods A total of 65 patients with Parkinson’s disease treated with STN-DBS were enrolled in this retrospective study including 54 cases of bilateral operations and 11 cases of unilateral operations. A total of 119 leads were implanted. The iMRI and 1-week postoperative MRI as well as intraoperative MER were applied. Results Two leads were found to be obviously deviated from the planned targets by iMRI and were then re-implanted. No intracranial hemorrhage was found by iMRI scanning. The MRI taken 1 week post operation showed that 50 of 119 (42.0%) leads were away from planned targets (1-2 mm) in X axis and Y axis and 12 (10.1%) leads were as deep as 3 mm in the z axis. Minor hemorrhage in 5 sides and localized brain edema in 14 sides were found near the lead tips. Obvious brain edema on 1 side was found surrounding the lead by the MRI taken 1 week post operation. In bilateral operation, the number of MER tracks at the first operation side (right) were 1~3 tracks (63 tracks in total), and the number of MER track at the posterior operation side (left) were 1~5 tracks (90 tracks in total) (P=0.018). There was no significant difference in start-up voltage and UPDRS-III improvement rate between different groups in terms of electrode deviation at 1 month after operation(P=0.964, P=0.130), and there was no correlation between electrode deviation and UPDRS-III improvement rate(r=0.006, P=0.968). There was a correlation trend between the electrode deviation and the start-up voltage. Conclusions The techniques of iMRI and MER can be safely applied in DBS procedures. The iMRI could help discover apparent lead shift and complications timely and MER may facilitate the real-time fine adjustment of lead position. The electrode deviation of less than 2 mm might not affect the therapeutic effect, which, however, might needs higher stimulation voltage. Key words: Parkinson disease; Deep brain stimulation; Subthalamic nucleus; Magnetic resonance imaging; Microelectrode recording

Waste materials superuse and upcycling in architecture: design and experimentation

The research programme on the implementation of circular economy in the built environment, whose urgency is acknowledged both at national and at EU level, works on two complementary approaches: reuse ( superuse ) and recycling ( upcycling ). The first, theoretical and applied to a pilot case, is one of the first attempts to transpose to Italy the waste materials scouting and harvest mapping process as part of the design project. The second, with the start-up Atlante Inerti Project, which, with EIT funds, experiments an original use of recycled aggregates for the production of urban furniture elements with additive 3D printing and prefabrication of vibration compressed concrete, developing mixes with convincing performances of interest for further applications in the building industry.

Calumet acquires biolubricants start-up

Calumet acquires biolubricants start-up

An Empirical Study on the Quality Reliability of the Start-up performance of the Fixed Wing Aircraft at low temperature

An Empirical Study on the Quality Reliability of the Start-up performance of the Fixed Wing Aircraft at low temperature

AI start-up Atomwise raises $45 million

AI start-up Atomwise raises $45 million

Exelon invests in storage startup.

Exelon invests in storage startup.

Stop the Insanity — Startup and Commissioning Begin on Day One

Stop the Insanity — Startup and Commissioning Begin on Day One

Key Success Factors for ICT Service Startup Team : Team Creativity, Knowledge Sharing and Absorptive Capacity

Key Success Factors for ICT Service Startup Team : Team Creativity, Knowledge Sharing and Absorptive Capacity

Research of public supply system reorganization plan for Businesss Start-up company and Medium and small enterprises

Research of public supply system reorganization plan for Businesss Start-up company and Medium and small enterprises

A study on the crowdfunding strategies of start-up businesses -focusing on the impact of perceived justice on customer satisfaction and loyalty-

A study on the crowdfunding strategies of start-up businesses -focusing on the impact of perceived justice on customer satisfaction and loyalty-

Start-up training opens to all

Start-up training opens to all

Proposals to improve government funding of domestic start-up businesses through Living Lab: Focus on Korea Credit Guarantee Fund

Proposals to improve government funding of domestic start-up businesses through Living Lab: Focus on Korea Credit Guarantee Fund