In this paper, the statistical inference of the stress-strength reliability for a K-out-of-N: G mixed standby system with switching failure is investigated. It is assumed that the strength of the component itself and the external stress to which it is subjected are random variables that obey the same distribution. If an operating component fails, the warm standby component will be immediately switched to the operating one. During this switchover, the warm standby component is subject to switching failure with a certain probability. Based on Weibull distribution and generalized half-logistic distribution, the reliability indices of stress-strength model under two different distributions are derived, respectively. For the two types of distribution of stress and strength, the maximum likelihood estimator, maximum spacing estimator, Bayesian estimator, asymptotic confidence interval and bootstrap-p confidence interval of the reliability are obtained, respectively. The Monte Carlo method is applied in the numerical simulation to realize the simulation inference of the system reliability. The performance of the above inference methods is analyzed and compared. The influence of parameters of stress and strength on the system reliability is analyzed graphically.