In this paper, we describe an approach for building a hybrid Bayesian network-based multi-agent system for drug crime knowledge management. We use distributed artificial intelligence architecture to create a multi-agent information system that integrates distributed knowledge sources and information to aid decision-making. Our comparison of the hybrid system with a previously developed stand-alone expert system Sherpa, which was in use at a large drug crime investigation facility, shows that the current system compares similar to the existing system in terms of efficiency and effectiveness of knowledge management. We illustrate how the proposed hybrid bayesian network-based can be implemented in the distributed computing network environment.