Stable Sites Research Articles

Electronic and light absorption properties of metal adsorbed In2Se3 monolayer

With its excellent optical and electrical characteristics, two-dimensional (2D) In2Se3 has a lot of potential uses in flexible electronics, photodetectors, and phase-change memory, and so on. In this study, we have systematically investigated the electronic structure and light absorption properties of a metal atom adsorbed monolayers of In2Se3 using density functional theory. The findings indicate that the most stable sites of different metal adsorbed In2Se3 monolayer materials are different. All metal atoms adsorbed In2Se3 (M-In2Se3) systems have good stability. After the adsorption of metal atoms on all M-In2Se3 systems, it can be seen by their energy band structures that all systems exhibit metallic behavior. It is illustrated that the adsorption of metal atoms can modulate the change of In2Se3 material from semiconductor to metal. Similarly, the densities of states plots show the metallic nature of the M-In2Se3 system structure and indicate that adsorbed metal atoms can change the properties of the In2Se3 material itself. And interestingly, in the M-In2Se3 system, the ultraviolet (UV) region exhibits significantly enhanced absorption peaks, demonstrating that the addition of metal atoms can improve the In2Se3 material’s ability to absorb light. Finally, reference light absorption spectrum, it is found that placing spherical metal nanoparticles on top of 100 nm thick In2Se3 nanosheets could excite the localized surface plasmon resonance. And among them, Au nanoparticles have the most impact on the localization of electric fields. It indicates that the introduction of Au significantly enhances the absorption properties of the material. This suggests that the metal atom adsorbed In2Se3 system will be favorable for its application in optical devices as well as electronic devices.

Highly dispersed and stable NiSn subnanoclusters encapsulated within Silicalite-1 zeolite for efficient propane dehydrogenation

Propane dehydrogenation (PDH) is one of the most effective methods for intentional (“on-purpose”) propylene production. Isolated Sn sites on open supports exhibit considerable PDH performance comparable to that of industrial Pt- and Cr-based catalysts, but the loss of Sn is inevitable. Herein, highly dispersed and stable NiSn subnanoclusters encapsulated within the channels of silicalite-1 zeolite are fabricated through a one-step hydrothermal synthesis in this work. The as-prepared Ni1Sn1@S-1 zeolite catalyst exhibits outstanding PDH performance with considerable propylene formation rate (ca. 12.3 mmol∙gcat-1∙h−1) and high propylene selectivity (>88 %). Most significantly, no Sn loss is detected after three regeneration cycles. Structural elucidation of NiSn sites on catalysts, by HRTEM, H2-TPR, FTIR and XPS characterizations confirms that the Ni sites embedded in the geminal silanols of zeolitic framework play a vital role in anchoring Sn species and preventing the active sites from losing and sintering. The cooperative action of robust NiSn subnanoclusters is conducive to the selective C–H activation and the propylene desorption. A plausible dehydrogenation mechanism is revealed by in situ infrared spectroscopy. This study on siliceous zeolite confined NiSn catalysts delivers an insight into the nature of selective and stable NiSn sites involved in the PDH reaction.

Solvent-free Synthesis of Transition Metals Nanoparticles Decorated Foamy Flakes-like Nitrogen-doped Carbon as Bifunctional-catalyst for High-performance Rechargeable Zn-air Batteries

Transition metal-nitrogen-carbon (M/NC) demonstrates a promising effective electrocatalyst for enhancing oxygen evolution/reduction reactions (OER/ORR). However, synthesizing these catalysts is often complex, time-consuming, and involves hazardous solvents while producing a low yield. This work introduces a versatile, eco-friendly, and straightforward solvent-free method to produce M/NC (M = Co, Ni, and Fe) catalysts in ~3 h using a glucose, urea, and metal nitrate hydrate mixture. The high-yield M/NC catalysts exhibit a porous architecture and uniform distribution of metal nanoparticles within a foaming flakes-like nitrogen-doped carbon matrix. The metal nanoparticles are wrapped with protective nitrogen-doped carbon layers, producing stable active sites. Possessing these unique properties, the obtained M/NC catalysts show high-performance and stable bifunctional OER/ORR. As the best result, Co/NC presents an OER/ORR potential difference (ΔE) of 0.78 V and retains 96% and 89% of its OER and ORR performance after a 10 h stability test. In practical application, the Co/NC-based Zn-air battery depicts a high power density of 184 mW cm−2 and good rechargeability of up to 120 h, outperforming the battery with noble metal-based catalysts. This work sheds light on the versatile, eco-friendly, and scalable synthesis of M/NC catalysts while presenting a strategy to accelerate the generation of inexpensive and highly effective bifunctional OER/ORR catalysts.

A dataset of JLS-5-20M black soil image in Northeast China

This is a dataset of the surface reflectance data covering some black soil areas in the three northeastern provinces of China, based on the L1 data of the JL1GP satellites’ multispectral imager with a spatial resolution of 5-20 meters. Specifically, we adopted the on-orbit absolute calibration technology based on multiple stable sites to ensure that the on-orbit absolute radiometric calibration accuracy of the JL1GP satellites’ multispectral imagers is no less than 7%. Then, we selected the L1 data of JL1GP satellite multispectral imager that imaged in the three provinces of Northeast China with clear weather and no clouds are as the input image of atmospheric correction process. Finally, the L1-level image data are atmospherically corrected and orthorectified by the atmospheric correction algorithm based on the atmospheric radiative transfer model, to generate the reflectance product dataset covering some black soil areas in the three northeastern provinces of China with an absolute accuracy of no less than 7%. This dataset takes advantage of the domestic JL1GP satellites’ advantages of high spatial resolution, a large number of bands, and stable imaging quality, hence it can provide reliable support for quantitative remote sensing applications in the black soil areas of the three northeastern provinces in China.

Nanoparticulate WN/Ni3C Coupling in Ceramic Coatings for Boosted Urea Electro‐Oxidation

AbstractUrea electrolysis can convert urea from urea‐rich wastewater to hydrogen for environmental protection and sustainable energy production. However, the sluggish kinetics of urea oxidation reaction (UOR) requires valence‐variable sites that are generally active at high anodic overpotentials. Herein, a robust ceramic coating is constructed with coupled tungsten nitride (WN)/nickel carbide (Ni3C) nanoparticles to achieve valence‐stable catalytic sites with outstanding UOR performance. Various characterization results indicate strong interfacial electron transfer from WN to Ni3C in coupled nanoparticles, which enables reservation of Ni2+ sites without self‐oxidation during UOR, quite distinct from the kinetically slow Ni3+OOH‐catalyzed UOR pathway. Theoretical calculations show that the coupled effect in WN/Ni3C leads to enhanced electron transfer from catalytic sites to adsorbed urea, and W sites are thermodynamically favorable for UOR. This efficiently lowers the barrier of rate‐determining step (RDS: *CO‐N2 → *CO·OH), thus enabling fast UOR kinetics and a low potential of 1.336 V at 100 mA cm−2, which identifies this ceramic coating as one of the best UOR electrocatalysts. This work opens a new avenue for design of stable and active sites in ceramics coatings toward advanced electrocatalytic applications.

Enhanced electronic, optical, and mechanical properties of penta-BCN by doping metal elements

In this wrok, the electronic structure, optical and mechanical properties of penta-BCN doped with Cu, Ag and Au at different point sites are investigated based on first principles method. The results show that X @ N system has the smallest binding energy, which indicates that the N site is the most stable doping site. The band gap of all doping systems becomes smaller and the conductivity is enhanced. The Cu@C system and Au@C system introduce magnetism, and the Ag@C system undergoes a transition from semiconductor to metal. The optical properties of the X @ N system show that doping enhances the response of system to photoelectrons in the infrared region. The real part, imaginary part, refractive index and reflectance of doping system are all enhanced compared to penta-BCN, especially the Au@N system. The research of mechanical properties indicates that the Young's modulus of Au@N system decreases, showing that the hardness of Au@N is smaller, but the Poisson 's ratio is larger compared to penta-BCN. The stress-strain curve shows that its ideal strength is 22 %. The results will provide theoretical help for the research of nano-spintronic devices and infrared photodetectors.

Cobalt Stabilization through Mesopore Confinement on TiO2 Support for Fischer-Tropsch Reaction.

Cobalt supported on mesostructured TiO2 catalysts has been prepared by a wet-impregnation method. The Co/TiO2 catalytic system showed better catalytic performance after support calcination at 380 °C. Co nanoparticles appeared well distributed along the mesopore channels of TiO2. After reduction pretreatment and reaction, a drastic structural change leads to mesopore structure collapse and the dispersion of the Co nanoparticles on the external surface. Along this complex process, Co species first form discrete nanoparticles inside the pore and then diffuse out as the pore collapses. Through this confinement, a strong metal-support interaction effect is hindered, and highly stable metal active sites lead to better performance for Fischer-Tropsch synthesis reaction toward C5+ products.

Surface evolution of AlGaN nanowire decorated by cesium atoms: A first principle study

Surface decoration with cesium on the photocathode is an effective method to reduce surface barriers and promote electron emission. In this study, we investigated the changes in surface properties of AlGaN nanowire coated with Cs atoms using first-principle calculations. The N bridge site is the most stable site for a single atom deposition. As more Cs atoms are deposited on the surface, the average adsorption energy increases along with the weakened ionization of Cs adatoms. The Bader charge of surface Al and Ga atoms undertake significant changes in comparison with tiny alteration of N atoms, especially for Al atom with a decrease of 0.41 |e|/atom. The variation in surface work function reaches a maximum of 2.3 ∼ 2.5 eV at Cs coverage of 0.5 ∼ 0.75 ML, which can be attributed to the synergistic effect of dipole length and charge redistribution. The donor states underneath CBM induced by the orbital overlap of Al-p, Ga-p and Cs-d electrons accompanied by the downward band bending in the band structures. This work provides theoretical insight into the surface evolution of Cs-decorated AlGaN nanowires and offers guidance for the development of state-of-the-art nanostructured vacuum devices.

Angular dependent potential for Al-Zr binary system to study the initial heterogeneous nucleation behavior of liquid Al on L12-Al3Zr

A new binary Al-Zr angular dependent potential (ADP) is developed with force-matching method based on the ab initio reference data. The potential can predict the accurate properties for pure Al, such as lattice constant, elastic constants, point defects, especially the melting point. It can also ensure that the L12-Al3Zr crystal is in solid state when the Al crystal is in liquid state. The interfacial stability (work of adhesion, Wad) of Al/ L12-Al3Zr interfaces calculated with this potential agrees well with the first-principles’ results. The initial heterogeneous nucleation behavior of liquid Al on L12-Al3Zr crystal was studied with molecular dynamics based on this potential. Liquid Al atoms preferred to nucleate on the AlZr-terminated L12-Al3Zr(100) surface, due to the fact that there is only one stable adsorption site for Al atoms on this surface. The growth behavior of liquid Al atoms is decided by the orientation of L12-Al3Zr crystal surface.

Adsorption capacity of a hydrogen atom on the 2D silicon carbide surface

Hydrogen adsorption on two-dimensional (2D) silicon carbide (SiC) was studied using molecular dynamics and ab initio calculations. By investigating a converged density functional theory (DFT) calculation, the stable adsorption sites of a hydrogen atom on the 2D SiC were found at the top sites (T­Si and T­C, of which the most stable adsorption site is T­Si). The adsorption of a hydrogen atom on 2D silicon carbide led to local structural changes in silicon carbide.

Density functional theory study on the interactions between H4POx (X = 6,7,8) groups and F,Si-doped reduced CeO1.979(111) surfaces

The structure of F,Si-doped reduced CeO1.979(111) surfaces were studied using DFT+U method, and the interaction between F,Si-doped CeO1.979(111) surfaces and H4POx (X = 6,7,8) groups on KDP surfaces was studied. The adsorption potential energy surface, bonding structure and electronic structure of stable adsorption of H4POx groups in the interaction systems were calculated and analyzed. The results indicate that the oxygen vacancy formation energy on the Ce0.979Si0.021O1.979(111) surface decreases by 1.396 eV, while on the CeO1.958F0.021(111) surface increases by 0.271 eV. The most stable adsorption sites of H4PO6, H4PO7, and H4PO8 groups have changed to the Cebri, Ot, and Ot sites on reduced surfaces. Two Si-O bonds and two Ce-O bonds on Ce0.979Si0.021O1.979(111) surface are broken to form a cavity. The number of Ce-O(H4POx) bonds and H bonds between Ce0.979Si0.021O1.979(111) surface and H4POx groups decreases by one. The number of Ce-O(H4POx) bonds and H bonds between the CeO1.958F0.021(111) surface and H4POx groups is still 3 and 2, but the bonding length is shortened. After the interaction between three reduced surfaces and H4POx groups, the band gaps all narrow and exhibit semi-metal properties. There was no charge transfer between Si and O(H4POx) in Si-doped system, while Bader charge transfer between O(H4POx) and Ce increase in F-doped system. The density of states of Ce0.979Si0.021O1.979(111) and CeO1.958F0.021(111) surfaces with H4POx groups move towards lower energy levels, and the latter moves more and is more stable.

Efficient olefin epoxidation with high turnover rates over ordered mesoporous silica nanoparticles with uniform manganese sites

Olefin epoxidation has been studied over a series of mesoporous manganese silicate nanoparticles and tBuOOH. Partial substitution of Si by Mn in silica framework leads to highly dispersed, distorted Mn(III) sites, confirmed by various physicochemical analyses. High conversion and stable styrene oxide, stilbene oxide and epoxy cyclohexane yield have been achieved with MS75 with 1:1.5 ratio of olefin: oxidant. However, at faster reaction rates lower styrene oxide yield is observed at lower Mn-containing catalyst (MS100). High TON, TOF over manganese sites shows accessible monomeric Mn sites. Attributed to high reactant density at redox-active Mn silicate sites due to facile diffusion across shallow pore depth channels of nanoparticulate om-MSx and surface hydrophobic characteristics. The catalysts were found to be stable under recycling and filtration experiments. The excellent stability against leaching of active manganese species indicates stable sites and good textural properties in om-MSx, essential for extended activity.

An optimal method for quantifying the facial sebum level and characterizing facial sebum features.

Evidence suggests that sebum content is important in skin disorders such as acne. However, sebum levels change depending on the external environment, and quantifying skin sebum levels is challenging. Here, we propose an optimal method for quantifying the facial sebum level. Four hundred and sixty participants (160 males and 300 females) aged 20-40 were enrolled in this study. A Sebumeter SM 810 was used to measure the sebum level at five facial locations: the forehead, the chin, the left cheek, the right cheek, and the nose. The participants were divided into two groups; one group underwent a one-time measurement (n=390, male: female=120: 270), and the other underwent three consecutive measurements (n=70, male: female=40: 30). The casual sebum level (CSL) was measured in all patients after a 30-min acclimatization; subsequently, the sebum removal process was conducted, followed by a resting period of 1h to determine the sebum excretion rate (SER). Spearman's correlation analysis and the Wilcoxon signed-rank test were used to compare the sebum level consistency and differences between the groups. Although three consecutive measurements better reflected the sebum content, the one-time measurement also represented the relative sebum level. One hour after sebum removal, the sebum level recovered to 70%-90%; thus, this method was applicable for use in SER quantification. Of the five testing points, the sebum content was highest in the nose and lowest in the cheeks (both left and right). In addition, the cheeks were the most stable sites in terms of testing points, testing times, and CSL/SER values. A one-time measurement of the CSL could represent the SER 1h after the sebum removal. In our cohort, the sebum level of males with oily skin was decreased at age 32-35, and that of males with non-oily skin increased at 28-35. The opposite trend was observed in female participants. Sebum measurement methods were assessed, including testing times, indices (interval of time) and sites in a conditioned external environment. A one-time measurement of the CSL 1h after sebum removal was sufficient to determine the sebum level and SER, and the cheeks are recommended as the testing site. Sex and skin type differences were observed in sebum level changes with age.

Phosphate (Bio)mineralization Remediation of 90Sr-Contaminated Groundwaters.

Historical operations at nuclear mega-facilities such as Hanford, USA, and Sellafield, UK have led to a legacy of radioactivity-contaminated land. Calcium phosphate phases (e.g., hydroxyapatite) can adsorb and/or incorporate radionuclides, including 90Sr. Past work has shown that aqueous injection of Ca-phosphate-generating solutions into the contaminated ground on both laboratory and field scales can reduce the amount of aqueous 90Sr in the systems. Here, two microbially mediated phosphate amendment techniques which precipitated Ca-phosphate, (i) Ca-citrate/Na-phosphate and (ii) glycerol phosphate, were tested in batch experiments alongside an abiotic treatment ((iii) polyphosphate), using stable Sr and site relevant groundwaters and sediments. All three amendments led to enhanced Sr removal from the solution compared to the sediment-only control. The Ca-citrate/Na-phosphate treatment removed 97%, glycerol phosphate 60%, and polyphosphate 55% of the initial Sr. At experimental end points, scanning electron microscopy showed that Sr-containing, Ca-phosphate phases were deposited on sediment grains, and XAS analyses of the sediments amended with Ca-citrate/Na-phosphate and glycerol phosphate confirmed Sr incorporation into Ca-phosphates occurred. Overall, Ca-phosphate-generating treatments have the potential to be applied in a range of nuclear sites and are a key option within the toolkit for 90Sr groundwater remediation.

Nanoscale Investigation of Bubble Nucleation and Boiling on Random Rough Surfaces.

Surface roughness is one of the significant factors affecting liquid-vapor phase change heat transfer. This paper explores the effect of surface roughness on bubble nucleation and boiling heat transfer, as well as the microscopic mechanism, by constructing random rough surfaces using molecular dynamics (MD) simulation. Bubbles randomly nucleate on a flat surface and tend to nucleate in pits on rough surfaces. The pits on the random rough surface gather more argon atoms than the protrusions, forming low potential energy regions on the surface, thus providing stable nucleation sites for bubbles. As the surface roughness increases, bubble generation, merging, and growth are advanced. In addition, rough surfaces offer a larger effective heat transfer area for the heat transfer process, increase the strength of solid-liquid coupling, and obtain smaller solid-liquid interaction energy. The critical heat flux (CHF) value positively correlates with surface roughness. As the roughness increases, the surface superheat at the onset of CHF decreases accordingly. This paper provides new insights into the mechanism of heat transfer enhancement on rough surfaces and surface design in thermal management.

Dynamic Metastable Characteristics of Carbon Cages Embedded with Er2C2.

Novel endohedral metallofullerenes (EMFs), namely, Er2C2@C2v(5)-C80, Er2C2@Cs(6)-C82, Er2C2@Cs(15)-C84, Er2C2@C2v(9)-C86, Er2C2@Cs(15)-C86, and Er2C2@Cs(32)-C88, had been experimentally synthesized, and the unique structures and many fascinating properties had also been widely explored. Nevertheless, the position of the Er atoms inside the cage shows a severe disorder within the stable EMF monomer, which is difficult to understand and explain from the experimental point of view. In this work, based on the density functional theoretical calculations, the Er2C2@Cs(6)-C82 has 73 directional isomers and 2 Er atoms that are far beyond from Er-Er single bonding and tend to be close to the cage side (marked as "shell"), and the core (Er2C2 units) takes on a butterfly shape as generally revealed. The energy difference between any two of the isomers is in the range of 0.05 to 25.6 kcal/mol, indicating a relatively easy thermodynamic transition between the isomers. The other five Er carbide cluster EMFs (Er2C2@C2v(5)-C80, Er2C2@Cs(15)-C84, Er2C2@C2v(9)-C86, Er2C2@Cs(15)-C86, and Er2C2@Cs(32)-C88) are also studied in the same way, and 30, 37, 39, and 43 most stable Er-oriented sites inside the cage, respectively, are obtained. In addition, the shape of the Er2C2 gradually changed from butterfly to linear. Moreover, the electronic structure and molecular orbital analyses show that it is easy for Er2C2@C80-88 to form a charge transfer state of [Er2C2]4+@[C80-88]4- via the dynamic core-shell coordination equilibrium. Er2C2 with a steep drop in chemical stability is restricted to forming varying degrees of metastable states in the shell, determined by the shell size, to ensure the overall stability. The lowest unoccupied molecular orbital energy level of these EMFs is increased by 0.5-1.1 eV compared with fullerenes C80-88, potentially providing favorable conditions for suitable energy level matching with EMF as an electron acceptor used in organic solar cell devices.

Electronic-ferry in metal element migration promoting deep activation of NiFe based phosphide for high efficient and stable oxygen evolution reaction

The design principle of high-efficient water electrolysis catalysis in oxygen evolution reaction (OER) has been primarily focused on the construction of multi-metal active centres. However, the spatial barrier between nonadjacent metal sites restricts the electron transfer, thus limits the activation and stability of active sites for improving the OER performance. Herein, a concept of electronic-ferry strategy by metal element migration in OER reconstruction is adopted to form dynamic electron-bridge between heterogeneous metal ions, which synchronously improves the OER kinetics and the corrosion resistance of metals centres. By designing layered NiCrP@NiFeP with concentration gradient, Cr element stepwise-release from the core part endows electron-ferry along the path of Ni2+-Cr4+/Ni3+-Cr6+ and Cr3+-Fe4+, achieving deep activated Ni(Fe)OOH layer with highly stable Fe sites in OER reconstruction process. The reconstructed NiCrP@NiFeP electrode shows 270 mV overpotential at 100 mA cm−2 current density with steady working more than 2600 h.

Localized ultrafine Cu clusters within MOF-derived metal oxides for collective photochemical and photothermal H2 generation

The ability to prepare ultrafine metal cluster (UMC) in supported catalysts, which exhibit extraordinary physical and chemical properties offers exciting opportunities to tailoring catalytic performance. However, the fabrication of singly-dispersed metal cluster catalysts that are both catalytic stable and active remains challenging. In this work, ultrafine Cu clusters has been spatially immobilized within the MOF derived photocatalyst matrix to realize a unitary photocatalyst with high density and stable active sites for charge separation and photothermal co-functions. Furthermore, the embedded Cu is capable of overcoming challenges related to porous structure collapse, disparate material interfaces and incompatibility between light absorption and charge transfer processes. Resultantly, the photocatalyst (m-TiO2/Cu) exhibits a high and stable H2 generation rate of 17.8 mmolg−1h−1 that is ∼69 times higher compared to the control. In essence, this study presents an efficient approach to immobilize ultrafine metal active sites for the development of high-performance heterogeneous catalysts for energy applications.

Proteomic profile of human gingival crevicular fluid reveals specific biological and molecular processes during clinical progression of periodontitis.

There is no clear understanding of molecular events occurring in the periodontal microenvironment during clinical disease progression. Our aim was to explore qualitative and quantitative differences in gingival crevicular fluid (GCF) protein profiles from patients diagnosed with periodontitis between non-progressive and progressive periodontal sites. Five systemically healthy patients diagnosed with periodontitis were monitored weekly in their progression of the disease and GCF samples from 10 candidate sites were obtained. Two groups of five sites, matched from an equal number of teeth, were selected from the five patients: Progression (PG) and Non-Progression (NP). Global protein identification was performed with high-throughput proteomic approaches and label-free analysis determined their relative abundances. Proteins were identified by Proteome Discoverer v2.4 and searched against human SwissProt protein databases. Enrichment bioinformatic analyses were performed in STRING-DB and ShinyGO environment. 1504 and 1500 proteins were identified in NP and PG respectively. Forty-eight proteins were exclusively identified in PG, while 52 were identified in NP. Moreover, 35 proteins were more abundant in PG and 29 proteins in NP (twofold change, p < .05). The NP group was mainly represented by proteins from "response to biotic stimuli and other organisms," "processes of cell death regulation," "peptidase regulation," "protein ubiquitination," and "ribosomal activity" GO categories. The most represented GO categories of the PG group were "assembly of multiprotein complexes," "catabolic processes," "lipid metabolism," and "binding to hemoglobin and haptoglobin." There are quantitative and qualitative differences in the proteome of GCF from periodontal sites according to the status of clinical progression of periodontitis. Progressive periodontitis sites are characterized by a protein profile associated with catabolic processes, immune response, and response to cellular stress, while stable periodontitis sites show a protein profile mainly related to wound repair and healing processes, cell death regulation, and chaperone-mediated autophagy. Understanding the etiopathogenic role of these profiles in progressive periodontitis may help to develop new diagnostic and therapeutic approaches.

Advances of Sulfonated Hyaluronic Acid in Biomaterials and Coatings—A Review

Hyaluronic acid (HA) is a non-sulfated glycosaminoglycan (GAG) that is a versatile material whose biological, chemical, and physical characteristics can be deeply tuned to modifications. However, HA is easy to decompose by hyaluronidase in vivo, and this process will reduce its structure and function stability during application. The sulfonation of HA can improve its stability under the action of hyaluronidase. Sulfated hyaluronic acid (S-HA) can be synthesized by many methods, and it shows significantly slower degradation by hyaluronidase compared with HA. In addition, negatively charged S-HA has other advantages such as anti-adhesive activity, anti-inflammatory, macromolecules by electrostatic interactions, stable site absorption of positively charged molecules, and enhancement of growth factor binding ability. It has numerous applications in medical (anti-aging, inflammation, tissue regeneration, cancer therapy, wound healing, and drug delivery) and cosmetics as biomaterials and coatings. In this article, the advances of S-HA for potential application of biomaterials and biomedical coatings will be reviewed and comprehensively discussed.