Effectiveness Of Stabilization Research Articles

Effectiveness of Dynamic Neuromuscular Stabilization and Flexibility Exercises for Non-Specific Low Back Pain in Bharatanatyam Dancer: A Case Study

Effectiveness of Dynamic Neuromuscular Stabilization and Flexibility Exercises for Non-Specific Low Back Pain in Bharatanatyam Dancer: A Case Study

STABILZED RAMMED EARTH- A REVIEW

Rammed earth construction has gained prominence as a sustainable building technique due to its eco-friendly nature and aesthetic appeal. However, ensuring the long-term durability of rammed earth structures remains a critical challenge. This paper investigates the efficacy of incorporating stabilizers, including cement, bagasse ash, and glass fibers, to address these concerns and enhance the performance of rammed earth structures. Drawing upon extensive research and experimentation, the paper examines the impact of stabilizers on material composition, structural integrity, and long-term durability. Through comparative analysis and empirical studies, the effectiveness of various stabilizers in improving compressive strength and resistance to weathering is evaluated. The role of cement as a traditional stabilizer is scrutinized, alongside emerging alternatives such as bagasse ash, a byproduct of sugarcane processing, and innovative additives like glass fibers. Furthermore, the paper investigates the influence of stabilizer incorporation on construction practices and life cycle considerations. Key factors such as cost-effectiveness, sustainability, and compatibility with traditional rammed earth methods are analyzed to provide comprehensive guidance for practitioners and researchers. The findings highlight promising avenues for enhancing the durability and compressive strength of rammed earth structures through stabilizer utilization. Practical recommendations are offered for implementing these strategies in real-world construction projects, emphasizing the potential for innovation and sustainability in contemporary architectural practice. Keywords: · Stabilized Rammed Earth · Un-Stabilized Rammed Earth

Throughflow effect on bi-disperse convection in Rivlin-Ericksen fluid

In this investigation, we delve into the influence of throughflow on the phenomenon of bi-disperse convection within Rivlin-Ericksen fluid. In the context of examining bi-disperse convection within this specific type of fluid, the throughflow effect is considered to have a uniform vertical distribution. The primary focus of this study centers on evaluating the system’s linear stability. To achieve this, we employ normal mode analysis to compute the Darcy-Rayleigh number at the onset of convection. This Darcy-Rayleigh number is computed for both stationary and oscillatory convection modes. Furthermore, we conduct a comprehensive analysis and present the results in graphical form to illustrate the impact of various parameters, including Peclet number and kinematic viscoelastic parameter, on both stationary and oscillatory convection. Our research findings demonstrate that when Peclet number Pr1 < 0, it leads to destabilising effect on both stationary and oscillatory convections. Conversely, when Peclet number Pr1 > 0, it induces stabilising effect on both stationary as well as oscillatory convections.

Development of spray‐dried oat milk powder with improved stability

AbstractBackground and ObjectivesOat milk is a plant‐based milk alternative and rich in various nutrients, however, the liquid product with a shorter shelf life limits its sales and consumption. This study is designed to develop an oat milk powder (OMP) using spray drying and improve the stability of reconstituted OMP by adding stabilizers.FindingsResults revealed that the optimal spray drying temperature was 160°C and the feed rate was 14 mL/min. The developed OMP showed higher bulk density compared to commercial soymilk powder. Furthermore, OMP maintained high contents of nutrients, including total phenol, β‐glucan, and various essential amino acids. The addition of stabilizers in OMP significantly decreased the turbidity and increased the pH stability, thermal stability, and freeze‐thaw stability of reconstituted OMP.ConclusionThe developed OMP product has abundant nutrients as well as stable physiochemical properties. Xanthan gum is the most effective stabilizer in improving the stability of reconstituted OMP across a wide range of pH and temperature.Significance and NoveltyThis study was the first to process oat milk into powder products and compare the effectiveness of different stabilizers in improving its stability. Our results suggest that OMP is a promising plant‐based beverage with stable physiochemical properties.

Effect of hydrolysis stabilizers on anti-aging performance of PET under pressure cooker test

Polyethylene terephthalate (PET) is extensively utilized in various industries due to its good properties. However, as a kind of polyester, PET is apt to hydrolysis when exposed to moisture and heat, which severely affects its performance and service life. Hence, the incorporation of hydrolysis stabilizers is a common mitigation method. In this work, the PET specimens modified by two types of hydrolysis stabilizers were subjected to the pressure cooker test to evaluate the improvement effect, and the resultant changes in appearance, mechanical properties, and thermal characteristics were studied. Additionally, the crystallinity and infrared peaks were detected to assess the effectiveness of the hydrolysis stabilizers and to reveal the aging mechanisms of PET. The results indicated that PET underwent three distinct aging processes during the pressure cooker test, including crystallization, water plasticization and hydrolysis, and the inhibitory effect of the hydrolysis stabilizers mainly reflected in the crystallization and hydrolysis processes while the effectiveness depended on their types and concentrations.

Use of Paper Ash and Lime as a Sustainable Stabilized Materials for Lateritic Soil

This research investigates the effectiveness of paper ash and lime for stabilizing lateritic soils in road construction applications. We assessed varying concentrations of paper ash and lime (0%, 3%, 6%, and 9%) to evaluate their effectiveness for soil stabilization. Initial analyses, including grain size distribution through wet sieving, specific gravity, moisture content, and Atterberg limits, were conducted to classify the soil. Following this, strength and compaction tests utilized standard proctor compactive energy, a method well-suited for field application. The findings indicated a general reduction in Atterberg limits (liquid limit, plastic limit, and plasticity index), an increase in maximum dry density (MDD), and a decrease in optimum moisture content (OMC) with increased concentrations of paper ash and lime. A thorough analysis of the results, along with a comparison to established standards, demonstrated significant improvements in soil properties. Specifically, the study found that 6% paper ash provided optimal stabilization, while 9% lime was effective as a stabilizing agent. These materials are suitable for use in the construction of subgrades and subbases for roads, aligning with AASHTO standards.

Evaluation of PEGylation efficacy of curcumin-loaded nanoemulsions using complementary methods to assess protein interactions and physicochemical properties

Nanoemulsions (NEs) are frequently used in the food, cosmetics and pharmaceutical industries to deliver nutraceuticals, pharmaceutical or cosmetic active ingredients. When administering NEs parenterally, various stabilisers are added to prevent rapid plasma clearance and to successfully deliver the active ingredient to the target site. For this purpose, PEGylation is often used to prolong the circulation time of the droplets. However, the problem is to determine the optimal concentration of the PEGylating agent – the PEGylation efficacy – that ensures adequate surface protection. This is a particular challenge when the active ingredient is incorporated into the stabilising layer, where any changes could disrupt the stability of the droplet. For this reason, we aimed to determine the optimal concentration of PEG2000-DSPE for surface protection of curcumin-loaded NEs for parenteral administration using electron paramagnetic resonance (EPR) spectroscopy. NEs were prepared using the high pressure homogenisation technique with 0.1 %, 0.3 % or 0.6 % of the PEGylated phospholipid. A droplet size of approximately 100 nm and polydispersity index below 0.25 indicated suitability for parenteral application. EPR analysis showed that PEG2000-DSPE had a stabilising effect on selected NEs, which was most pronounced in the part of the stabilising layer closest to the aqueous phase. To confirm these results, protein interaction studies were carried out using dynamic light scattering, UV–Vis spectroscopy, atomic force microscopy and release studies from protein-enriched media – bovine serum albumin (BSA) or foetal bovine serum (FBS) in phosphate-buffered saline. These analyses confirmed that the addition of PEG2000-DSPE reduced protein binding to the droplets as a function of concentration, with 0.3 % providing the best protection for the droplets. Our conclusions from the EPR spectroscopy study demonstrate the usefulness of EPR in determining the optimal concentrations of PEGylating agents for surface coverage and its usefulness in the formulation development phase.

Evaluating Stabilizing Effects of Geosynthetics in Flexible Airport Pavement Structures by FE Analyses

Evaluating Stabilizing Effects of Geosynthetics in Flexible Airport Pavement Structures by FE Analyses

Modification and Stabilization of Collapsible Loess Using Diammonium Phosphate Solution

The collapsible loess will rapidly soften and lose its bearing capacity when soaked in water. Under a mild condition (20 °C), the biomimetic inorganic agent, diammonium phosphate (DAP), reacts with calcite in the collapsible loess, producing a stronger bonding material, hydroxyapatite (HAP), to modify and stabilize the soil. Uniaxial compression, permeability tests, and morphological analysis using X-ray diffraction and scanning electron microscopy equipped with an energy X-ray dispersive system were used to assess the effectiveness of DAP stabilization on the collapsible loess. The results indicated that HAP improved the inter-particle bonding within the loess, filled the pores within particles, reduced the permeability, and consequently mitigated the collapsibility of the loess. The compressive strength of the DAP-treated loess increased as DAP concentration increased. Following 28 days of curing, the compressive strength of the loess treated with a 3.0 mol/L DAP solution was six times greater than that of the untreated group. DAP’s reinforcement effect on the loess was superior to that of cement. The compressive strength of the DAP-treated loess was about double that of the cement-treated loess and the permeability coefficient was reduced by more than 50% at equivalent solid content. Furthermore, DAP generated 82% fewer carbon emissions compared to Portland cement. Considering eco-friendly and sustainable development, DAP offers a more competitive alternative for modification and stabilization of loess.

Clinical case of management of a patient with Duchenne muscular dystrophy caused by deletion of exons 50–52 of the DMD gene against the background of pathogenetic therapy with viltolarsen

Duchenne muscular dystrophy (DMD) is the most common lumbar-limb muscular dystrophy with an X-linked recessive type of inheritance. It is characterized by a debut at an early age, rapidly progressive atrophy of the striated musculature of the limbs, trunk, heart muscle, which leads to loss of motor skills, severe cardiovascular and respiratory complications.
 Currently, a number of new drugs have appeared for the pathogenic therapy of MDD, the effectiveness of which is the most during its early initiation in the ambulatory stage of the disease. One of the new methods of MDD treatment is antisense oligonucleotide therapy. The application of this type of therapy is possible for certain mutations in the DMD gene and is recommended immediately after diagnosis. At the moment, the duration of this method of treatment in the Russian Federation is only a few years.
 In our article we discuss a clinical case of the study of a patient suffering from Duchenne muscular dystrophy caused by the deletion of 50–52 exons in the DMD gene, who is on therapy with steroids and Viltolarsen.
 A special feature of the case is the late application of Viltolarsen from the age of 9 years. The results of the observation demonstrate a significant effect in stabilization of motor skills, of the functioning of the cardiovascular and respiratory systems, which gives a chance to slow down the course of the disease, improve the quality of life and increase its duration, even taking into account the late initiation of pathogenic therapy.

Collection and transportation of SARS-CoV-2 and influenza A virus diagnostic samples: Optimizing the usage of guanidine-based chaotropic salts for enhanced biosafety and viral genome preservation

Many virus lysis/transport buffers used in molecular diagnostics, including the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA, contain guanidine-based chaotropic salts, primarily guanidine hydrochloride (GuHCl) or guanidine isothiocyanate (GITC). Although the virucidal effects of GuHCl and GITC alone against some enveloped viruses have been established, standardized data on their optimum virucidal concentrations against SARS-CoV-2 and effects on viral RNA stability are scarce. Thus, we aimed to determine the optimum virucidal concentrations of GuHCl and GITC against SARS-CoV-2 compared to influenza A virus (IAV), another enveloped respiratory virus. We also evaluated the effectiveness of viral RNA stabilization at the determined optimum virucidal concentrations under high-temperature conditions (35°C) using virus-specific real-time reverse transcription polymerase chain reaction. Both viruses were potently inactivated by 1.0 M GITC and 2.5 M GuHCl, but the GuHCl concentration for efficient SARS-CoV-2 inactivation was slightly higher than that for IAV inactivation. GITC showed better viral RNA stability than GuHCl at the optimum virucidal concentrations. An increased concentration of GuHCl or GITC increased viral RNA degradation at 35°C. Our findings highlight the need to standardize GuHCl and GITC concentrations in virus lysis/transport buffers and the potential application of these guanidine-based salts alone as virus inactivation solutions in SARS-CoV-2 and IAV molecular diagnostics.

Effect of antipsychotics and mood stabilisers on metabolism in bipolar disorder: a network meta-analysis of randomised-controlled trials

Antipsychotics and mood stabilisers are gathering attention for the disturbance of metabolism. This network meta-analysis aims to evaluate and rank the metabolic effects of the commonly used antipsychotics and mood stabilisers in treating bipolar disorder (BD). Registries including PubMed, Embase, Cochrane Library, Web of Science, Ovid, and Google Scholar were searched before February 15th, 2024, for randomised controlled trials (RCTs) applying antipsychotics or mood stabilisers for BD treatment. The observed outcomes were twelve metabolic indicators. The data were extracted by two reviewers independently, and confirmed by another four reviewers and a corresponding author. The above six reviewers all participated in data analyses. Data extraction was based on PRISMA guidelines, and quality assessment was conducted according to the Cochrane Handbook. Use a random effects model for data pooling. The PROSPERO registration number is CRD42023466669. Together, 5421 records were identified, and 41 publications with 11,678 complete-trial participants were confirmed eligible. After eliminating possible sensitivity, risperidone ranked 1st in elevating fasting serum glucose (SUCRA=90.7%) and serum insulin (SUCRA=96.6%). Lurasidone was most likely to elevate HbA1c (SUCRA=82.1%). Olanzapine ranked 1st in elevating serum TC (SUCRA=93.3%), TG (SUCRA=89.6%), and LDL (SUCRA=94.7%). Lamotrigine ranked 1st in reducing HDL (SUCRA=82.6%). Amisulpride ranked 1st in elevating body weight (SUCRA=100.0%). For subgroup analyses, quetiapine is more likely to affect indicators of glucose metabolism among male adult patients with bipolar mania, while long-term lurasidone tended to affect glucose metabolism among female patients with bipolar depression. Among patients under 18, divalproex tended to affect glucose metabolism, with lithium affecting lipid metabolism. In addition, most observed antipsychotics performed higher response and remission rates than placebo, and displayed a similar dropout rate with placebo, while no between-group significance of rate was observed among mood stabilisers. Our findings suggest that overall, antipsychotics are effective in treating BD, while they are also more likely to disturb metabolism than mood stabilisers. Attention should be paid to individual applicability in clinical practice. The results put forward evidence-based information and clinical inspiration for drug compatibility and further research of the BD mechanism. The National Key Research and Development Program of China (2023YFC2506200), and the Research Project of Jinan Microecological Biomedicine Shandong Laboratory (No. JNL-2023001B).

Sliding mode controller with neural network compensation for tank

The control effectiveness of the all-electric tank stabilizers directly affects the firing accuracy of the tank gun. In order to improve the firing accuracy of the moving tank, this paper proposes a sliding mode control (SMC) strategy using neural network feed-forward compensation for the tank bidirectional stabilizers. SMC technology can quickly and effectively deal with uncertainties, unmodeled terms, and external disturbances in complex tank systems. Neural networks possess the advantage of approximating arbitrary continuous functions in finite time, realizing the estimation of SMC control errors with feed-forward compensation. The Lyapunov stability analysis proves that the designed controller can achieve asymptotic stabilization in finite time. Finally, both co-simulation and physical experiments are conducted. The results show that the proposed control strategy possesses better tracking speed and tracking accuracy compared to the conventional controller and exhibits strong robustness.

Diversification strategies have a stabilizing effect for income and food availability during livelihood shocks: Evidence from small-scale aquaculture-agriculture systems in Myanmar during the COVID-19 pandemic

CONTEXTDiversification is an important strategy used by millions of small-scale food producers globally to improve yields, farm profitability, and food security. Diversification can also enable small-scale producers to cope better with livelihood shocks. However, it is not always clear through which pathways diversification practices can stabilize livelihoods and food security in small-scale production systems, especially in the context of the recent COVID-19 pandemic. OBJECTIVEIn this study we examined whether and how diversification practices stabilized income and food availability in small-scale food production systems during the COVID-19 pandemic. The diversification practices explored in this study included fish polyculture and integrated aquaculture-agriculture (IAA), and their combination. We compared small-scale systems employing different combinations of these diversification strategies, with systems that did not contain them. METHODSWe analyzed 300 surveys of small-scale aquaculture producers in Myanmar. Structural equation modeling was applied to examine the multivariate relationships between the adoption of diversification practices among the small-scale producers, and whether and how the adoption stabilized their livelihoods during the COVID-19 pandemic in Myanmar. RESULTS AND CONCLUSIONSWe find that the integration of diversification practices in different small-scale aquaculture-agriculture (SSAA) production systems had generally positive effects for the stabilization of income, food availability or both during the COVID-19 pandemic. The novelty of the study is the unraveling of the differentiated pathways between production models that enabled these stabilization processes emerge. We find major divergences in the stabilization potential between polyculture and IAA, both in terms of the magnitudes of the stabilization effects and the pathways. Polyculture generally offered more significant stabilizing effects than IAA. Surprisingly the highest and more significant positive effects for the stabilization of food availability came through the purchase of food items from extra fish/crop income, rather than their increased self-consumption. SIGNIFICANCEOverall, the SSAA production systems combining different diversification practices could form proactive strategies to help small-scale food producers cope with livelihood shocks.

Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery

ObjectivesTo investigate the mechanism by which intestinal epithelial cell (IEC) death induces arthritis.MethodsIEC death was assessed by staining for necroptosis and apoptosis markers and fluorescence in situ hybridisation at different...

Use of Dynamic Spinal Instruments (Dynesys) in Adult Spinal Deformities According to Silva-Lenke and Berjano-Lamartina Classifications.

Adult spinal deformities (ASD) present complex challenges in spine surgery. The diverse nature of these deformities requires a comprehensive understanding of their classification and treatment options. Traditional approaches, such as fusion and rigid stabilization are associated with complications, including screw loosening, breakage, proximal junctional kyphosis (PJK), and pseudoarthrosis. Dynamic stabilization techniques have emerged as promising alternatives, to reduce these complications and preserve spinal motion. This study investigated the effectiveness of dynamic stabilization using the Dynesys system in the surgical treatment of adult degenerative spinal deformities, with a particular emphasis on their classification. ASDs were classified according to the Berjano-Lamartina (BL) and Silva-Lenke (SL) classifications. We analyzed the efficacy of the Dynesys system in enhancing sagittal balance, radiological parameters, and clinical outcomes in this context. Dynamic stabilization of patients with ASDs using the Dynesys system significantly improved the visual analog scale and Oswestry Disability Index scores and decreased the complication rates. Patients with BL types 2, 3, and 4 experienced a significant improvement in sagittal balance followed by sagittal vertical axis measurements (p = 0.045, p = 0.015, and p < 0.0001, respectively). The SL and BL classifications, which were originally developed for rigid spinal stabilization, can be applied in dynamic stabilization. Furthermore, dynamic stabilization using the Dynesys system can be used as an alternative to rigid stabilization in SL levels 2 and 3, and BL types 1, 2, and 3, and in some patients with type 4 ASDs.

Re-purposing the built environment of urban China: Residential eldercare and David Harvey's capital switching in a new era

In urban China, institutional eldercare interacts with local land markets in ways that present special analytical problems in critical political economy. It is a new sector: home-based eldercare and childcare have formed complementary parts of intergenerational household strategies that are coming under system-wide pressure for the first time. Growth in Chinese institutional eldercare has increasingly contributed to the repurposing of a wide range of disused buildings, with noteworthy state encouragement. We read this post-reform feature of urban transformation to deploy David Harvey’s concept of ‘capital switching’ in new ways that are emerging in studies of China's urban geography. Harvey’s framework has already been used in analysing China’s multi-decade boom in the built environment. It exposed the stabilising effects of diverting capital from overaccumulation in single turnover and realisation cycles into deferred returns in the multi-cycle built environment albeit complicated by complex and distinctive interpenetrations of consumption fund and fixed capital, for-profit and not-for-profit sectors, state and non-state interests, and so on. This certainly speaks to the origins of contemporary Chinese urbanisation booms. But repurposing for institutional eldercare now appears to be playing a role in abating mounting overaccumulation and potential devalorisation in the built environment, pairing these unprofitable buildings with for-profit eldercare services operating and yielding profits in repeated single turnover cycles. We experiment with bundled commodity theory to understand repurposing buildings for residential eldercare in this new context.

Global potential energy surface survey of pentanitrogen cation

We reported hitherto the most extensive isomeric, interconversion and decomposition landscape of the pentanitrogen cation (N5 +) at the CCSD(T)_CBS//MP2/cc-pVTZ, CBS-QB3 and CCSD(T)_CBS//CCSD/cc-pVTZ levels. A maximum number of eleven isomers and fourteen transition states were located, among which three and eight were reported for the first time. Moreover, the counterion stabilisation effect by the model BF4 − anion as well as the solvation effect in anhydrous HF solvent at different temperatures were investigated. Notably, although 01 is rather well known, a new type of N2-extrusion process for the 01 salt (with BF4 − counterion) was identified.

Analysis of the effectiveness of landslide stabilization in a near-dam reservoir area

The geological conditions of the landslide area in a near-dam reservoir area of a water conservancy hub project are complicated, and the stability problem of the landslide body is prominent, which is not only directly related to the safety of the adjacent office building and highway, but also poses a threat to the normal operation of the water conservancy hub. According to the latest geological data of the landslide area, the results of the stability calculation of the landslide body are analyzed, and the reinforcement design scheme of circular chair type anti-slide piles &amp; prestressed anchor cables is proposed for the landslide body to solve the problem of anti-slide stability of the landslide body. Numerical analysis results show that: the safety factor under each working condition after reinforcement is within the permissible range and meets the relevant normative requirements, the landslide body has good control effect on deformation after reinforcement, and the reinforcement measures can provide certain reference value for the design and construction of similar projects.

Effectiveness of dynamic neuromuscular stabilization, neurodevelopmental techniques and proprioceptive neuromuscular facilitation on trunk and gait parameters in patients with subacute stroke: A three-arm parallel randomised clinical trial

Background Today, stroke is the principal cause of demise in both developed and developing countries. There are different techniques used to treat patients with sub-acute stroke. Trunk muscles play a key role, i.e. in keeping the spine and trunk in place. This stabilization requires moving the head and extremities freely and selectively. The aim of this study is to compare the effectiveness of dynamic neuromuscular stabilization (DNS), neurodevelopmental techniques (NDT) and proprioceptive neuromuscular facilitation (PNF) on trunk and gait parameters in the subacute phase of stroke. This study is intended to ascertain the efficacy of all three approaches individually and to compare the effectiveness of DNS, NDT and PNF on trunk and gait parameters. Furthermore, the findings of this study could be used to assist post-stroke survivors in their early recovery and improve their level of independence. Methods In this interventional study, participants will be divided into three groups, and in each group, 20 patients will be assigned randomly to each group using the sequentially numbered opaque sealed envelope method. Group A patients will be given DNS, Group B will be given NDT, and Group C will be given PNF. The patients will be given treatment for five days for four consecutive weeks. Outcome measures that will be used are trunk impairment scale (TIS), dynamic gait index (DGI) and gait parameters. Data will be collected before and after the 4-week treatment period. Conclusions After the study, a conclusion will be drawn regarding which treatment technique is most suitable among all the three strategies for treating stroke patients if the hypothesis of the study is found valid. Clinical Trials Registry – India (CTRI) reference no. CTRI/2022/06/043037; date of registration 22/05/2022.