The article is based on the information published in foreign and Russian sources and media, as well as on the basis of the authors own research and interviews carried out in Syria. The aim of the work is to study the situation of Syrian Christians after the events of the Arab Spring-2011. This is the scientific novelty of the topic. The article is devoted to the problems that not only touched, but most dramatically affected the life of Christians in Syria, who traditionally presented at least 12% of its population (and much more in the past). They are representatives of the most indigenous religion in the Syrian Arab Republic (SAR). The work also traces the role of Christians in the history and socio-political life of Syria, analyzes their current situation, evaluates the events of recent years and draws appropriate conclusions. In particular, the author believes that the Arab Spring led not only to huge human and economic losses, but also to serious ethno-confessional structural changes in the society of the SAR. With the possible disappearance of this native part of the Syrian population, who lived here and represented almost all the inhabitants of that region before the Islam, the republic may lose not only 12 percent of the most educated and active part of its population, but also its tourist attractiveness in the eyes of the whole world. Although Syria has always been considered the cradle of Christianity it could lose its reputation as one of the most tolerant countries of the Arab world.