Starting from February 2022, with the beginning of the russian federation’s unprovoked aggression against Ukraine, the time requirements for the direction of the trainings and the contingent for which they are intended have changed significantly. In addition, the issue of rapid spread of knowledge and skills in providing first aid to the injured persons has become very acute. The active help of the international community of higher medical education institutions contributed to the quick and effective training of our teachers as trainers for Basic Life Support (BLS), Stop Bleeding and PHTF courses. The use of innovative digital technologies, modeling of clinical situations, in particular, with the help of distance learning tools, the possibilities of modern simulation technologies and simulators allowed applicants to acquire the necessary theoretical knowledge and master practical skills quickly and at the best level. The objective: to perform a comparative assessment of the quality of conducting simulation trainings on providing pre-medical care to persons without basic medical education using various teaching techniques. Materials and methods. The trainings were conducted in two formats - traditional offline study with the participation of an instructor and using the HybridLab method (introduced by the Lithuanian University of Medical Sciences, Kaunas, Republic of Lithuania) for 112 schoolchildren and 27 teachers. 58 students and 14 teachers were trained according to the usual method in groups of 5-6 persons, according to the HybridLab method – 54 schoolchildren and 13 teachers in groups of 3-4 individuals. The duration of the trainings was 42 hours. Efficiency was evaluated according to two criteria: the average score of the final test and the indicator of acquiring new knowledge. Results. A unique combination of methods of organizing the educational process, such as HybridLab, trainings on pre-medical care, which were developed on the basis of the trainings “First on the scene”, “Stop the bleeding” and BLS, and modern tools that allow to evaluate the effectiveness of training, contributed to the achievement a high level of mastery of all the necessary skills by as many people as possible in the shortest time, which is the leading goal of today. Conclusions. We consider the experience of implementing these knowledge/skills and training methods, as well as the further evaluation of their effectiveness, to be the second task of all medical education institutions and training centers operating in Ukraine, after teaching training on tactical medical training of combatants and emergency tactical medical assistance for medical specialists.