Spray Type Research Articles

The COPD Foundation's COPD360Net Initiative Approach to Patient-Centric Drug Development: A Case Study in Using Patient Surveys to Inform New Treatments for Viral Respiratory Infections.

Patient-centric drug development is crucial to creating treatments that address unmet patient needs but is often ignored. The COPD Foundation's COPD360Net® includes a multistakeholder approach for operationalizing patient-centric development of treatments where patients, caregivers, scientists, and clinicians review opportunities based on scientific merit, potential to address an unmet need, and feasibility of adoption. COPD360Net deploys large-scale online community surveys to review profiles of potential therapies based on those criteria. This approach was implemented to inform the development of an intranasal spray to prevent viral respiratory infections (VRIs), a major cause of exacerbations in people with chronic lung diseases. Insights included: Of the 376 respondents with COPD surveyed, frequent exacerbators reported strong interest in a new type of antiviral nasal spray to prevent VRI.Patient survey and advisory committee insights demonstrated that a pan antiviral nasal spray has potential high value to both clinicians and patients and informed the COPD360Net decision to partner on its development.Including patient perspectives from the outset can be conducted efficiently by mobilizing an engaged online patient community.

Tiered human health risk assessment of antibacterial quaternary ammonium compounds (QACs) in dishwashing detergents

Quaternary ammonium compounds (QACs) are widely used in consumer products because of their unique antibacterial properties, and dishwashing detergents are a major source of exposure through oral, inhalation, and dermal routes. The three classes of QACs, including benzalkonium chloride (BAC), n-alkyldimethylethylbenzylammonium chloride (ADEBAC), and di-n-alkyldimethylammonium chloride (DDAC), in spray and non-spray types of dishwashing detergents were quantified by high-performance liquid chromatography-mass spectrometry. A tiered risk assessment approach was also considered. In the Tier 1 assessment, the mean and worst-case exposure were estimated to screen for rough exposure and risk levels. In the Tier 2 assessment, mean and upper-tail exposure levels were calculated based on the exposure parameters of Korean consumers using Monte Carlo simulation. QACs had a low frequency of detection of up to 20% in dishwashing detergents, and the contents of detected QACs varied depending on the individual samples. Based on the results of the Tier 1 assessment, BACs and DDACs posed potential health risks via inhalation and dermal routes. Tier 2 assessment suggested that the current level of oral and dermal exposure of Korean consumers to QACs in dishwashing detergents is unlikely to pose a health risk, even for upper-tail exposure groups. However, the present results suggest that spray-type DDACs may pose a health risk in the upper-tail inhalation exposure group, and further investigation is required to clarify this risk.

Investigation on Water Immersing and Spraying for Cooling PV Panel

The use of photovoltaic cells has increased dramatically in recent years. However, the photovoltaic cells convert most of the solar radiation into heat, and this heat negatively affects the PV productivity. Therefore, a cooling system can get rid most of this heat. An experimental and theoretical examination is conducted for the augmentation of PV power and efficiency by using two different water cooling systems. The PV cooling has been equipped with two types of water-cooling systems, i.e. immersion, and spraying. For the immersion cooling, the temperature decrease is achieved but the power output has been low. On the other hand, the water spraying cooling has been studied at three different chilled water flow rates. The solar simulator having an average radiation of 1300 W/m2 is generated through 50 W halogen lights for testing. It has been found out that a 60% temperature reduction has been achieved, with a remarkable increase in power output by 59% and efficiency by 8%. However, no remarkable difference has been achieved by varying water flow rates. Therefore, cooling by spraying system has given better results than immersion. Finally, the experimental results have been found to be consistent with the numerical results.

전기자동차용 구동모터 오일 냉각 순시해석

Typical traction motors of electric vehicles utilize water jacket-based or air-based cooling. Currently, lightweight traction motors are preferred to extend the range of electric vehicles. As a result, direct cooling techniques have garnered significant attention from researchers. Direct coil-based cooling methods are of two types: oil injection type and oil spraying type. Direct oil-based cooling methods exhibit high cooling capacities. In this study, we investigate the transient increments in temperature in 160 KW traction motors. To this end, the power losses of motors were estimated using JMAG software . Using two-phase computational fluid dynamics (CFD) simulation over a duration of 18 s, the transient increase in temperature was predicted . The CFD predictions agreed well with the experimental observations, with an error less than 5%. We expect that the conclusions of this study will contribute to the improvement of the cooling performance of 160 KW traction motors.

Targeted drug delivery to the inferior meatus cavity of the nasal airway using a nasal spray device with angled tip

Background and Objective: Nowadays, by advancement in computational tools, Computational Fluid and Particle Dynamics (CFPD) technique can be used more than ever. The main aim of this study is using a nasal spray device with angled tip to deliver drug particles to the inferior meatus cavity for treatment purposes. In the present study, the drug delivery to the lower regions of the nasal cavity will be improved that has been considered less in the literature.Methods: For this purpose, a spray with an angled tip was used, and the deposition of sprayed particles was compared with a spray with a straight tip. Based on the objectives presented above, a realistic model of the nasal route, including facial geometry, and paranasal sinuses obtained from a series of Computed tomography (CT) scan images, as well as the geometry of a nasal spray with two types of tip were developed.Results: It is observed that by using the spray with the straight tip, particles were mainly deposited in the middle and superior regions of the nasal cavity and no particles entered the inferior meatus airway. The results proved that the spray with the angled tip improved the regional deposition percentage in the inferior meatus cavity up to 2.4% of the total sprayed particles and 1 mg drug mass delivered to this region. The majority of these particles had a diameter between 15–55 µm and that could be considered by spray designers to produce more compatible sprays with the targeted region. Also, most particles were deposited near the inferior meatus cavity and so there is a strong chance to be absorbed and delivered to this region.Conclusion: The deposition pattern and particle size contour due to the spray with the angled tip can give sight to the designers and producers of nasal sprays to build more efficient types for better targeted drug delivery purposes. With this spray type, deposited particles were observed in the inferior meatus that never happened with the straight type. Also, the angled tip of the nasal spray shows the benefit of the ease of use for the user.

The Effect of Post-Heat Treatment on The Mechanical Properties of FeCrBMnSi Coatings Prepared by Twin Wire Arc Spraying (TWAS) Method on Pump Impeller From 304 Stainless Steel

The Twin Wire Arc Spray (TWAS) is one of the most widely used types of thermal spray coating because of its low cost, high efficiency and can also be used for mass production. However, heat treatment after the Fe-based amorphous coating process uses the TWAS method on pump impellers made of 304 stainless steel are not well documented. The purpose of this study is to determine the effect of post heat treatment after FeCrBMnSi coating with the TWAS method to increase wear resistance on pump impeller materials made of 304 stainless steel. In this study, NiAl and FeCrBMnSi were used as bond coats and top coats. Before the coating process, the substrate materials were sandblasted to obtain a surface roughness of 75 - 100 µm. The coating process is carried out by setting parameters of current spraying (A), voltage spraying (V), compressed air pressure (Bar), and standoff distance (mm) each of 150; 28.4; 5; and 400. Post heat treatment was carried out at a temperature of 500°C and 700°C for 3 hours using Furnace Chamber Thermolyne F6010. Tests of thickness, microhardness (ASTM 92-82), wear rate (ASTM G99-95A), micrography (ASTM E3), SEM, and adhesive strength (ASTM D- 4541) have been completed. The results of this study indicate specimens with post-heat treatment produce a coating layer with better mechanical properties than specimens without post-heat treatment. Specimens with post-heat treatment at a temperature of 700°C for 3 hours resulted in the smallest total wear rate of 6.6x10-4 mm3/s.

RESEARCH OF OPTIMIZATION OF LAMES OF THE LASER SENSOR OF VIBRATION TO COUNTER LASER INTELLIGENCE SYSTEMS

One of the most vulnerable issues in the technical protection of information is the receipt of data, private or confidential, due to leakage through the optoelectronic channel, the main source of data is laser acoustic intelligence systems or laser microphones. There are active and passive methods of protection against laser acoustic reconnaissance systems (ACS). Active methods use various noisy or vibrating devices that pose a danger to human health. With passive protection, it is recommended to use either special corrugated windows or completely closed shutters, which create some inconvenience now. Detecting a working laser microphone is very difficult and in some cases technically impossible. For example, the removal of information using ACS occurs through glass building structures, usually windows. This article is devoted to the analysis of the principle of operation of laser systems of acoustic intelligence and passive methods of reading acoustic information. Triangulation laser sensors are designed for non-contact measurement and control of position, movement, size, surface profile, deformation, vibration, sorting, recognition of technological objects, measuring the level of liquids and bulk materials. Accordingly, they can be used to study the vibrational properties of glass and films applied to them. It is described the method of working with laser triangulation vibration sensors, which allows to study the deviations of glass from different manufacturers from sound vibrations, thereby investigating the anti-laser properties of existing glass, as well as different types of spraying and films. In addition, this method allows you to conduct and test deviations from sound vibrations for new types of glass, films and spraying, proving the results of spectral studies and their impact on the amplitude of vibration of the glass. The vibration sensor was adjusted and the software parameters were experimentally optimized to obtain the truest deviation values ​​required to work with sprayed samples for passive protection.

Synergistic effect of acidic environmental exposure and fatigue loads on FRP tendons

The synergistic effect of acidic environmental exposure and fatigue loads on fiber-reinforced polymer (FRP) tendons was investigated in this study. The fatigue behavior of basalt FRP tendons under cyclic loads and exposed to air, water, and acid was evaluated. Three types of fatigue tests, that is, air, water spraying, and acid spraying tests, were performed at 40 °C. Another set of preconditioned specimens was prepared by immersing in an acid solution without stress for a designated period. Fatigue stresses of 25%fu–65%fu (where fu is the tensile strength) were applied at a stress ratio of 0.5. The failure mechanism was analyzed at macroscopic and microscopic scales. The results showed that water spraying had the most negligible impact on fatigue behavior, and the acid spraying specimens exhibited 58% faster degradation than the water spraying specimens. Moreover, the synergistic effect of the acid and cyclic stress facilitated the failure process of the acid spraying specimens by 43% compared to the preconditioned specimens. The internal pressure generated by the ingress liquid accelerated resin cracking and fiber–matrix interface debonding. Furthermore, the synergistic effect of the acid and fatigue loads accelerated degradation, owing to the combined effect of internal pressure and chemical corrosion.

Development of an Artificial Neural Network Utilizing Particle Swarm Optimization for Modeling the Spray Drying of Coconut Milk.

Spray drying techniques are one of the methods to preserve and extend the shelf-life of coconut milk. The objective of this research was to create a particle swarm optimization–enhanced artificial neural network (PSO–ANN) that could predict the coconut milk spray drying process. The parameters for PSO tuning were selected as the number of particles and acceleration constant, respectively, for both global and personal best using a 2k factorial design. The optimal PSO settings were recorded as global best, C1 = 4.0; personal best, C2 = 0; and number of particles = 100. When comparing different types of spray drying models, PSO–ANN had an MSE value of 0.077, GA–ANN had an MSE of 0.033, while ANN had an MSE of 0.082. Sensitivity analysis was conducted on all three models to evaluate the significance level of each parameter on the model, and it was discovered that inlet temperature had the most significant influence on the model performance. In conclusion, the PSO–ANN was found to be more effective than ANN but less effective than GA–ANN in predicting the quality of coconut milk powder.

Determination of granule (prill) movement modes in the prilling tower for mineral fertilizer production

The object of research is the mode of movement of the granules of mineral fertilizers obtained in the towers. The subject of research is the effect of the physical and chemical properties of granules, their size and initial hydrodynamic parameters on the speed of movement of the granules in the tower. The fertilizer industry is characterized by high requirements for the production of mineral fertilizers, which makes it promising to use granulation plants of large unit capacity, tower production. The resulting product must have a stable physical and chemical composition, be monodisperse with a spherical shape of granules, which allows long-term storage in bulk without the use of auxiliary equipment and meet international quality standards. The main granulation equipment that is used in the tower production of mineral fertilizers is spray type granulation equipment. In such towers, there is a likelihood of crossing pellet flares, getting pellets into the walls of the pelletizing tower and adhesion of the melt on this surface in industrial conditions, which leads to negative consequences. Therefore, the determination of the modes of motion of granules is still important. Methods of mathematical modeling of the movement of granules under different conditions were used in the work. Numerical methods were used to solve the equations of differential equations. As a result, an equation was obtained to determine the speed components along the x and y axes. The calculation of the horizontal speed of the granule and the determination of the time of its movement in the working area of the prilling tower makes it possible to determine the length of the granule path in this direction, to determine the diameter of the spray torch of the granules. Provides information on preventing the ingress of granules into the walls of the prilling tower and adhesion of the melt on this surface in industrial conditions, which leads to negative consequences. The magnitude of the speed, especially for the vertical component, changes its value several times over time due to a change in the mode of motion of the granules when moving from the granulator down the tower. This indicates the need to also take into account the change in the value of the resistance coefficient over time. When deriving the equations, simplifications were used, and the motion of a solid granule was considered. However, a drop begins to move from the granulator (disperser), which then crystallizes into a granule. Comparing the obtained results, allowing to predict by calculation the behavior of the spray plume of granules, with the initial ones obtained in industrial conditions, it is possible to conclude that the error of the equations obtained is 10.5%. Therefore, work on improving the obtained equations describing the mode of motion (speed) of the granules will be continued.

Hygienic evaluation of the most common methods of agricultural crops treatment with chemical protection products (literature review)

Global strategies, including application of chemical plant protection products, are important in the cultivation of safe corps and preservation of human health. A promising area of preventive medicine, agronomy, agroecology and agroengineering is the optimization of methods of pesticide formulations application. The aim of the work was a hygienic assessment of the most common and latest methods of crops treatment with chemical pesticides. Results. The biological effectiveness of different types of pesticides is achieved by different application rates of the working solution. The most common method of pesticide application is spraying, which ensures the application of pesticides in the drop-liquid state and is characterized by low consumption of active substance per unit area, variable-controlled distribution on the treatment surface, provides good adhesion and retention on facilities, allows the use of combined formulations. One of the most effective ways to minimize the negative impact of chemical plant protection products and achieve economic success is a rational approach to the choice of pesticide application, as it takes into account the hazard class of pesticides, the presence of water protection zones, the sensitivity of target crops, etc. Conclusion. Rational application of pesticides includes minimizing the overall effect of pesticides on human health and the environment and achieving high-targeted biological efficiency. Adherence to the methodology of choosing the type of pesticide application and selection of the type of spray is a key point in optimizing the rational use of chemical plant protection products, which requires a detailed study from the standpoint of both efficiency and safety. Control over compliance with the recommendations should be included in sanitary-hygienic and sanitary-ecological monitoring.

Control of growth and flowering of chrysanthemum (Dendranthema x grandiflorum Kitam.) using day length extension and Red Light Night Break

Abstract In tropical areas, since the day length (DL) is shorter than the critical DL for chrysanthemum (Dendranthema x grandiflorum Kitam.), chrysanthemum flowers before reaching the required stem length (SL) for cut flower. Two experiments were conducted with the aim of determining critical DL for vegetative growth of chrysanthemum genotype; to attain a required SL and promote vegetative growth of chrysanthemum using night break (NB) with red light for spray type of chrysanthemum. In the first experiment, DL was extended by one, two, and three hours using white fluorescent light (WL) after sunset. In the second experiment, red light (RL) was applied at the middle of the night for 15, 30, or 45 minutes to break the night. The experiments were laid out in completely randomized design with four replications. The results indicated DL extension with WL and RL night breaks had significant effect on vegetative characters and biomass yield. Similarly, flower bud initiation, coloring and blooming were significantly affected. NB using RL had a significant effect on flower diameter. The three hours DL extension (12+3 hours) totally inhibited flowering of chrysanthemum genotype, which can be considered a critical DL for Hawa1. NB with RL for 15, 30, or 45 minutes effectively inhibited flowering of chrysanthemum. In conclusion, breaking the night with RL at the middle of the night for 15 minutes with small amount of intensity (9.42 µmolm-2s-1) is enough to inhibit flowering and promote stem elongation of chrysanthemum Hawa1.

Effect of the Different Soil Types on Chrysanthemum Cut Flower Quality

Cultivating annual crops in the high upland has the potential to increase avalanche and land erosion. Therefore, chrysanthemum extensification from high upland to medium upland can create sustainable agriculture. The differences between high upland and medium upland are microclimate and soil type. Meanwhile, the effect of soil type between the high upland and the medium upland on the chrysanthemum spray type quality is unknown. The study aimed to determine the effect of different soil types on the quality of chrysanthemums when planted in high upland. The study used a split plot design with two factors. The first factor was the type of soil, such as Andosol from the high upland and Latosol from the medium upland. The second factor was the chrysanthemum varieties, such as Yastayuki (white flower), Arosuka Pelangi (yellow flower) and Socakawani (red flower). The results showed that both Andosol and Latosol soil types could produce the same quality of chrysanthemum in all varieties when planted in high upland. The quality aspects of chrysanthemum were the plant height, the stem diameter, the number of flowers and flower color. Consequently, we could extend the cultivation of chrysanthemum in medium upland by using Latosol type soil.

Effects of pressure decay on Non-Methane Volatile Organic Compounds (NMVOC) species distribution in domestic aerosol sprays with LPG propellants

Conventional aerosols sprays contain different Volatile Organic Compounds (VOC). These organic compounds have different properties and can have detrimental impact on air quality. This study investigated the spray performance and variation of the types of Non-Methane VOCs (NMVOCs) expelled over the life of pressurised aerosol spray can. Three types of aerosol sprays – hair sprays, deodorants, and antiperspirants were selected from the solvent-based cosmetic products. Mass Ratio (MR) of solvent (ethanol) to propellant (LPG) for all the products was analysed at pressure decay sequences of 4, 3, 2, and 1.5 bar. It was found that the MR in hair sprays expelled was significantly higher than that of antiperspirants and body sprays by 53% and 54% respectively at 4 bar. As the pressure depleted, however, the antiperspirant and body sprays’ MR decreased while that of the hair spray increased. At the lower pressures (2 bar), the hair spray had the highest MR and antiperspirant had the lowest. This finding is important in evaluating the performance of the delivery pathways of aerosol spray products and will provide insight into the effective design of atomisers with alternative “green” propellants like compressed air replacing LPG as the primary propellant in spray products.

Development and Utilization of a Model System to Evaluate the Potential of Surface Coatings for Protecting Grapes from Volatile Phenols Implicated in Smoke Taint

Due to the increasing frequency of wildfires in recent years, there is a strong need for developing mitigation strategies to manage the impact of smoke exposure of vines and occurrence of ‘smoke taint’ in wine. One plausible approach would be to prevent or inhibit the uptake of volatile phenols from smoke into grape berries in the vineyard. In this study we describe a model system we developed for evaluating under controlled conditions the effectiveness of a range of surface coatings (including existing horticultural sprays) for reducing/preventing the uptake of volatile phenols and their subsequent conversion to phenolic glycosides. Grapes were coated with the materials to be tested and then exposed to gaseous phenols, via evaporation from an aqueous solution, in a semi-closed glass container. Analysis of volatile phenols and their glycosidic grape metabolites demonstrated that the treatments typically did not provide any significant protection; in fact, some resulted in higher concentrations of these compounds in the grapes. The highest concentrations of volatile phenols and their glycosides were observed after application of oily, hydrophobic materials, suggesting that these materials may enhance the adsorption or transfer of volatile phenols into grape berries. Therefore, it is important to consider the types of sprays that are being applied in the vineyard before and during smoke events to prevent the potential of exacerbating the uptake of smoke compounds by grape berries.

Visualization of Commercial Coating Penetration into Fagus crenata Blume Wood Using a Non-Destructive X-ray Microtomography

Coatings can be used as a preservative method to protect the wood, especially the wood surface. The different component of the coating’s dependence of the purpose of it. The Japanese beech (Fagus crenata Blume) applied by several Japanese commercials coating materials. The coatings application used were spray type and brush type. X-ray microtomography in Fuji, Japan was used for visualized the coating samples. The X-ray target used were Cu, and Mo with Al filter. The X-ray image analysis in 2D and 3D were conducted using image J and VGStudio Max, respectfully. The coating’s containing materials and the concentration of it strongly affected the image result of X-ray microtomography visualization. The different X-ray target shows the different image results. The larger energy of X-ray (Mo with Al filter) is recommended to use for visualization. The X-ray images shows the penetration phenomena, which can be applied to calculate the penetration depth.

Nozzle Type and Driving Speed Effects on Spray Density of Aerial Application According to the Wind Tunnel Measurements

Spray density (Number of droplets/cm2) is an important component of agricultural spraying processes. In the field, assessment of the spray density under effect of a number of variables such as nozzle type and driving speed without take in account the effect of cross wind speed is insufficient. In this study, to simulate field spray operation, tests were carried out in wind tunnel using automatic spraying mechanism to investigate and to clarify effect of three types of flat fan nozzle tip spray at three driving speeds under effect three cross wind speeds on spray density. Water sensitive papers (WSPs) were used to collect spray density data. Spray density was calculated through image processing program software. Performance of spray nozzles was validated relative to experimental data of a TP11003 reference nozzle. Results indicated that XR11003 nozzle behavior was to some extent similar to that TP11003 nozzle under effect slow wind speed. It is also noticed that the spray density value decreased with increasing driving speed and wind speed, the spray density value with driving speed of 2.2 m/s and wind speed of 1 m/s was the best, reaching 64.3 droplet /cm2. While the spray density value with driving speed of 5.5 m/s and wind speed of 3 m/s was the least, reaching 3.8 droplet /cm2. The current study presents that the use of DG11003 nozzle gives the best control spray density data under effect very windy conditions to the reference nozzle.

Peptides on a rescue mission against the hazardous cidal chemicals used in Eastern Indian Agriculture: An in-silico approach based on field survey in 2020

Background: The use of poisonous agrochemicals is both necessary and menacing for a farmer. The long-term hazards of chemicals can even be life-threatening to many people. Recently, the adverse effects of such chemicals on the environment and human health received serious attention throughout the world. In an Indian context, the usage of the chemical sprays has costed many lives and influenced vital organs to the greatest extent. This serious situation advocates the search for ways to prevent the inhalation and absorption of these chemicals into the body. The present study was conducted to evaluate different types of chemical sprays, their impact, and explore remedial ways to neutralize their toxic effects. Methods: Alpha-cypermethrin, phorate, fenobucarb, buprofezin, and mancozeb were selected for binding based on the feedback of severity in actions reported by the respondents and statistical analysis of different physical and chemical parameters. Chemical similarity analysis of the 39 cidal chemicals was performed to predict the binding similarity with respect to the above-mentioned 5 seed molecules. These five chemicals were docked with three different proteins 121p GTPase HRas, Torpedo acetylcholinesterase, and trypanosoma phosphoglycerate kinase, selected based on the common target prediction. Results: Common target prediction revealed that these chemicals have an affinity to bind these proteins with a higher binding interaction towards the aromatic amino acid residues and those capable of H-bonding, escorted by a predilection towards acetylcholinesterase. Conclusion: The in-silico findings are the basis to propose that acetylcholinesterase can be considered as a potential binding agent to trap fatal agrochemicals.

Solvent evaporation kinetics in spray drying and how to consider heat loss

Real (diabatic) spray drying processes have heat loss that affects drying kinetics. The heat loss depends on process parameters and on the type of spray drying equipment. Practically, heat loss can be determined by evaporating the solvent of a specific spray drying process with measurement of the outlet temperature after process equilibration. In this work, models to calculate the droplet evaporation time from an adiabatic (perfectly insulated) spray drying process are further developed to take heat loss into account. Comparison of different calculation models from water evaporation trials on a modified Büchi lab spray dryer with results from ANSYS 13.0 CFD simulations, show a good agreement for the introduced equations where heat loss is considered.The advantage of knowing the droplet evaporation time is that it condenses all relevant parameters of a specific spray drying process including material properties of the solvent to one single parameter affecting evaporation kinetics. The knowledge of the droplet evaporation time is of significant importance for scale-up activities, process transfers and optimizations as well as for particle engineering purposes.

Analysis of the performance of direct contact heat exchange systems for application in mine waste heat recovery

Due to their relatively high thermal effectiveness and ease-of-use, direct contact heat exchange units are a favorable choice in heat recovery applications. Today, spray-based direct heat exchangers are commonly used for a variety of applications, including evaporative cooling and heat recovery. Yet in spite of their versatility, these heat exchangers are not well-understood, mainly due to their complex liquid/gas interactions, which may deem poorly-designed systems as undesirable and infeasible. Spray nozzle height and type (hollow and full cone), droplet diameter distribution, inlet air velocity and humidity, and water spray velocity are key parameters required to establish a clear understanding of direct heat exchange performance. To better understand such a multivariable phenomenon, this article offers a comprehensive study of the impact of these key factors. The main purpose of this study is to evaluate the validity of two different methods proposed for evaluating the performance of heat and mass transfer in large-scale direct contact heat exchangers, namely one-dimensional and three-dimensional approaches. The results of the present study show that while the one-dimensional approach is able to capture the experimental data within 10% of agreement with experiment, the three-dimensional approach reduces this error to 5%. In addition, this study aims to provide a framework to conduct future parametric studies with the goal of highlighting key performance factors understanding of which are a necessity for improved design of direct contact heat exchangers used in mine waste heat recovery applications. Novelty Statement To investigate the performance of an industrial-scale direct (spray) heat exchange system with a vertical configuration for application in mine waste heat recovery, two different models, namely; ‘1-D’ and ‘3-D’, are developed. Accuracy of two models in predicting heat transfer is evaluated through comparison with experimental data. A series of parametric studies are conducted to examine the impact of various operating parameters on the performance of heat exchange system.