Herbicides are used for integrated management of melaleuca (Melaleuca quinquenervia) trees to kill existing trees. Products with the herbicide active ingredients glyphosate, imazapyr, triclopyr, and hexazinone are used depending on the application method and other factors, including presence of non-target vegetation in the application area. Four application methods, foliar, frill-and-girdle, cut stump, and basal (applied to the soil) are used depending on extent of the population and other factors. Helicopter, truck, or all terrain vehicle (atv)-mounted sprayers, backpack sprayers, and hand-held spray bottles, and dropper bottles are used for application of herbicide. Various adjuvants may be added to the spray mixture to aid or modify the action of the herbicide or the physical characteristics of the mixture. A marker dye is often added to the spray solution to help visualize where herbicide is applied. This document is SS-AGR-258, one of a series of the Agronomy Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Original publication date October 2005.