This study aims to conduct a bibliometric analysis of the literature on the relationship between breast cancer and exercise using Citespace software, in order to explore the research hotspots, trends, and deficiencies in this field. Relevant literature including keywords such as “breast cancer” and “exercise” was retrieved from the Web of Science database and analyzed using Citespace software for data processing and visualization. The main conclusions of this study are as follows: In co-occurrence analysis of keywords, researchers mainly focus on the prevention, rehabilitation, and treatment of breast cancer, as well as the effects of different types of exercise on breast cancer. Meanwhile, the cooccurrence patterns of keywords in studies related to exercise and breast cancer indicate an increasing attention to the relationship between breast cancer and exercise, making it gradually one of the hotspots in breast cancer research. The timeline of keywords and burst detection analysis show that researchers have increasingly focused on the relationship between breast cancer and exercise in recent years, with research intensity showing an increasing trend year by year. Furthermore, in recent years, researchers have begun to emphasize the role of exercise in breast cancer rehabilitation, rather than just prevention and treatment. Discipline analysis indicates that research in this field involves multiple disciplinary areas, including medicine, oncology, sports science, nutrition, etc. Additionally, an analysis of papers published by country reveals that the United States leads in research on the relationship between breast cancer and exercise, followed closely by the United Kingdom, China, Canada, Australia, and other countries. Conclusion: Literature on the relationship between breast cancer and exercise shows a trend of increasing quantity year by year. However, there are still some deficiencies in this field, such as lack of uniform research methods, overly limited research samples, and insufficient rigor in research results. Therefore, further strengthening research on the relationship between breast cancer and exercise is highly necessary.