Breast Cancer Research Articles

Interactions between the diet, The gut microbiota and hormonal therapy in breast cancer

Interactions between the diet, The gut microbiota and hormonal therapy in breast cancer

Breast cancer with cervix, lung and neck metastases: a case report and literature review

Breast cancer with cervix, lung and neck metastases: a case report and literature review

Synergistic response of PEG coated manganese dioxide nanoparticles conjugated with doxorubicin for breast cancer treatment and MRI application

In this research work, we designed a smart biodegradable PEG-coated MnO2 nanoparticles conjugated with doxorubicin (PMnO2-Dox NPs) for dual chemo-photodynamic therapy and magnetic resonance imaging (MRI) application. This highly sensitive pH-responsive PMnO2-Dox NPs causes effective drug release under acidic pH environment. PMnO2-Dox NPs not only improves the efficacy of chemo-photodynamic therapy due to synergistic response as well as improved MRI imaging via boosting T1 MRI contrast. Manifold characterization techniques have been employed for materials investigation. Crystallography of PMnO2-Dox NPs were performed by using XRD analysis, which confirmed tetragonal crystal structure with an approximate crystallite size of 20–30 nm. Surface morphology was confirmed via SEM analysis, results indicated the spherical and asymmetric agglomerated nanocluster of PMnO2-Dox NPs. In in vitro bioassay, the anticancer activity of PMnO2-Dox NPs were tested against breast cancer (MCF-7) cell line using MTT test. Moreover, it can also inhibit the growth of primary and secondary cancers without light exposure. Results suggested that PMnO2-Dox NPs not only convenient for cancer treatment via combined chemo-photodynamic therapy but also address the way towards a comprehensive strategy for MRI application via bright contrast agent T1 after overcoming the problem of multidrug resistance (MDR) and synergistic response of therapeutic analysis.

A Remotely Delivered, Aerobic And Resistance Exercise Training Program For Mental Health In Women Living With And Beyond Breast Cancer

A Remotely Delivered, Aerobic And Resistance Exercise Training Program For Mental Health In Women Living With And Beyond Breast Cancer

Accurate determination of body composition of patients with breast cancer through MRI image analysis

Accurate determination of body composition of patients with breast cancer through MRI image analysis

Artificial intelligence in action: Improving breast disease management through surgical robotics and remote monitoring

ObjectivesThis article aims to discuss the transformative impact of artificial intelligence (AI) on the identification and management of breast diseases, with a specific focus on breast cancer. Materials and methodsHealthcare providers have integrated AI technologies such as surgical robots and remote monitoring systems to improve the accuracy and efficiency of breast disease diagnosis and treatment. ResultsSurgical robots equipped with AI algorithms provide real-time guidance to surgeons, analyze imaging data, and ensure precise procedures for better outcomes in breast cancer surgeries. AI-driven remote monitoring systems allow for close monitoring of patient health data, disease progression prediction, and personalized treatment recommendations. ConclusionsThe incorporation of AI technology into healthcare practices for breast diseases has revolutionized patient care delivery, enhancing outcomes, promoting patient engagement, and improving overall quality of care. These advancements offer personalized and tailored healthcare strategies that meet the unique needs of each patient, reshaping the healthcare industry.

Association between body composition and toxicities among patients with metastatic breast cancer (BC) treated with CDK4/6 inhibitors

Association between body composition and toxicities among patients with metastatic breast cancer (BC) treated with CDK4/6 inhibitors

Impact Of Multimodal Exercise Intervention On Sarcopenia In Breast, Prostate And Colorectal Cancer Survivors

Impact Of Multimodal Exercise Intervention On Sarcopenia In Breast, Prostate And Colorectal Cancer Survivors

Examining the feasibility of a dietetic intervention on body composition in irish breast and gynaecological cancer survivors: The LYSA trial

Examining the feasibility of a dietetic intervention on body composition in irish breast and gynaecological cancer survivors: The LYSA trial

Every Day Counts- a Randomized Nutrition and Physical Activity Pilot Intervention for Women with Metastatic Breast Cancer

Every Day Counts- a Randomized Nutrition and Physical Activity Pilot Intervention for Women with Metastatic Breast Cancer

Changes In Health-related Fitness After Breast Cancer Treatment In The AMBER Cohort Study

Changes In Health-related Fitness After Breast Cancer Treatment In The AMBER Cohort Study

Breast Cancer Survivors Exhibit Normal T-Cell Mobilization But Divergent Intracellular Cytokine Expression With Acute Exercise

Breast Cancer Survivors Exhibit Normal T-Cell Mobilization But Divergent Intracellular Cytokine Expression With Acute Exercise

Cardiometabolic Responses To Exercise Differ By Exercise Type And Intensity In Breast Cancer Patients

Cardiometabolic Responses To Exercise Differ By Exercise Type And Intensity In Breast Cancer Patients

The Effect Of Exercise-conditioned Human Serum On The Viability Of Breast Cancer Cells In Vitro

The Effect Of Exercise-conditioned Human Serum On The Viability Of Breast Cancer Cells In Vitro

Associations Between Domain-specific Physical Activity Levels And Physical Characteristics Of Behavior In Newly Diagnosed Breast Cancer Patients

Associations Between Domain-specific Physical Activity Levels And Physical Characteristics Of Behavior In Newly Diagnosed Breast Cancer Patients

Overcoming Exercise Barriers In The Early Recovery Phase Among Breast Cancer Patients

Overcoming Exercise Barriers In The Early Recovery Phase Among Breast Cancer Patients

Changes in body weight are associated with miRNAs modulation in patients with newly diagnosed breast cancer

Changes in body weight are associated with miRNAs modulation in patients with newly diagnosed breast cancer

Cold exposure therapy combined with bionic type I aggregation-induced emission photosensitizer for enhanced immunotherapy of breast cancer

Cold exposure therapy (CE), as an inexpensive method, has shown great potential in cancer therapy. Exploring the combined anti-tumor mechanism of CE and traditional therapies (such as photodynamic therapy (PDT)) is exciting and promising. Here, we have designed a bionic type I aggregation-induced emission photosensitizer system (named THL) for combined CE to explore the mechanism of combined therapy and enhance anti-tumor immune research. THL inherits the homologous targeting ability of tumor derived exosomes, promoting the enrichment of THL at the tumor site. Under external illumination, THL generates hydroxyl radicals and superoxide anions through type I PDT. In addition, mice were pretreated with cold exposure, which reduced the glucose and glutathione and enhanced THL mediated PDT and reactive oxygen species (ROS) generation. The results of experiments indicated this combination therapy increased production of ROS within the tumor, inhibited the growth of distant tumors, recurrent and rechallenged tumors and increased the number of cytotoxic CD8+T and memory T cells. Compared to PDT alone, combination therapy has shown greater advantages in tumor immunotherapy. The combination therapy strategy we designed has opened up a new paradigm of PDT and CE and provided new ideas for cancer immunotherapy.

Changes In Peak Oxygen Uptake, Ventilatory Anaerobic Threshold, And Power Output During Treatment Of A Stage II Breast Cancer Patient

Changes In Peak Oxygen Uptake, Ventilatory Anaerobic Threshold, And Power Output During Treatment Of A Stage II Breast Cancer Patient

Consumption of Fish High in Omega-3 Fatty Acids Is Associated with Less Peripheral Inflammation and Better Cognitive Function in Breast Cancer Survivors

Consumption of Fish High in Omega-3 Fatty Acids Is Associated with Less Peripheral Inflammation and Better Cognitive Function in Breast Cancer Survivors