Spontaneous Epileptic Seizures Research Articles

Circulatory and respiratory changes in spontaneous epileptic seizures in man.

Internal carotid artery (ICA) blood flow, mean arterial blood pressure (MABP), intracranial epidural pressure (EDP), and arterial blood gases were measured during spontaneous, generalized epileptic seizures in man. Concomitant with the clinical seizure there was a nearly threefold increase in ICA blood flow mainly caused by a rapid fall in cerebrovascular resistance (CVR). As changes in arterial blood gases after 30–45 sec of apnea and convulsions were moderate, the initial fall in CVR was attributed to local cerebral changes of either metabolic or neurogenic nature. Changes in MABP showed two different patterns during seizures, pattern 1 with a transient increase in pressure, and pattern 2 with a marked fall followed by an overshoot in pressure. The fall in MABP was probably caused by a Valsalva effect or a central nervous system vasodepressor response.

Intracerebral temperature changes in patients during spontaneous epileptic seizures

Intracerebral temperature changes in patients during spontaneous epileptic seizures

Spontaneous epileptic seizures and electroencephalographic changes in the course of phenothiazine therapy.

Spontaneous epileptic seizures and electroencephalographic changes in the course of phenothiazine therapy.

Sobressalto patológico: aspectos clínicos e eletrencefalográficos

Os autores relatam o caso de um paciente apresentando crises de sobressalto provocadas por estímulos auditivos, sensitivos e visuais, sem crises epilépticas espontâneas nem retardo psicomotor. Estudam os aspectos clínicos e eletrencefalográficos e revisam a situação da entidade entre as assim chamadas epilepsias reflexas.

FRACTURES OF THE SPINE COMPLICATING METRAZOL THERAPY

Convulsive therapy was first advanced by Ladislaus von Meduna of Budapest, Hungary. He conceived this form of therapy on the basis of reports as to the infrequency of the occurrence of both epilepsy and schizophrenia in the same individual and the fact that patients known to have schizophrenia had greatly improved or had recovered when spontaneous epileptic seizures developed. Meduna1said The theoretical basis for the therapy with cardiazol lies in the assumption that a certain biochemical antagonism exists between the convulsive state and the schizophrenic process. Meduna first experimented with animals, producing convulsions by injecting camphor. Jan. 2, 1934, he gave his first injection of a 25 per cent solution of oleum camphoratum to a patient for the purpose of producing a convulsion. He2found one patient in whom he could not produce a convulsion with camphor, so metrazol (cardiazol) was substituted. Cardiazol, or metrazol, is an