In this paper, we construct a nonlinear regularized Hermitian and skew-Hermitian splitting (NRHSS) iteration method for a class of nonlinear saddle-point systems. The NRHSS iteration method can be seen as a generalization of the Peaceman-Rachford splitting method with monotone plus skew-symmetric splitting (PRSM/MSS). Besides, if the nonlinear operator reduces to the linear case, the NRHSS iteration method reduces to the regularized Hermitian and skew-Hermitian splitting (RHSS) iteration method. Hence, the NRHSS iteration method can also be seen as a generalization of the RHSS iteration method. To overcome the heavy workload when direct solution methods are used, we also propose an inexact version of the NRHSS iteration method. Detailed theoretical analysis regarding the convergence properties is given. Numerical experiments on image deblurring problems are carried out to illustrate the feasibility and efficiency of the NRHSS iteration method.