A 16-channel integrated circuit charge sensitive preamplifier has been developed for a PET detector module that uses an 8/spl times/8 array of PIN photodiodes to identify the crystal of interaction. The amplifier, which is made using 1.2 /spl mu/m CMOS technology, produces an output of 100 mV per 1000 e/sup -/ input, and its noise performance is optimized for 10 pF detector capacitance. The rise time, fall time, bias current through the first FET, and detector current compensation are each controlled by a dc current applied to the 2 mm square chip. The Johnson noise (e/sup -/ fwhm at 1 /spl mu/s peaking time) is 173+13C, where C is the input capacitance in pF, and the shot noise (e/sup -/ fwhm) is 16.4/spl radic/(IT), where I is the detector dark current in pA and T is the amplifier shaping time in /spl mu/s. With this amplifier, the target noise of 300 e/sup -/ fwhm can nearly be met with 300 /spl mu/m depletion thickness photodiodes (3 pF, 200 pA per 3/spl times/3 mm element). >