This work is concerned with the influence of the finite-amplitude distortion of a driving diagnostic ultrasonic field on the collapse and rebound of a gas-filled spherical microbubble, present in the exposed compressible liquid. Such an analysis is especially important since one of the mechanisms for cavitation damage comes from the very large gas pressures generated at bubble collapse and in the subsequent pressure wave formed by bubble rebound. Gilmore's model [F.R. Gilmore, "The growth or collapse of a spherical bubble in a viscous compressible liquid," Hydrodynamics Lab. Rep. No. 26-4, California Institute of Technology, Pasadena, CA (1952)] for bubble dynamics is used to obtain the motion of the bubble interface when subjected to a pulsed diagnostic ultrasonic field of large amplitude. Knowledge of the bubble motion allows one to derive the pressure distribution around the bubble. Numerical results over a range of initial bubble sizes, acoustic pressures, and frequencies relevant to medical use show that the strength of the pressure spikes radiated by the rebounding bubble depends upon (i) the acoustic frequency (f), (ii) the initial bubble size (R0), and (iii) the magnitude of the pressure amplitude of the fundamental (PF) in a Fourier series description of the distorted pulse. As the pressure spikes propagate outward from the bubble wall, their strength is attenuated as the reciprocal of the distance from the center of collapse.