Spectral Compatibility Research Articles

Cognitive radar sequence design under the spectral compatibility requirements

Cognitive radar sequence design under the spectral compatibility requirements

Constrained radar waveform design algorithm for spectral coexistence

The design problem of radar waveform to enhance target delectability while ensuring spectral compatibility is considered. Precisely, an iterative sequential optimisation algorithm is developed to jointly optimise signal-to-interference-plus-noise ratio and stopband frequency energy. In each iteration of the proposed algorithm, the multidimensional optimisation problem is turned into multiple one-dimensional optimisation problems with closed-form solutions. Finally, the computational cost and objective value of the proposed algorithm in comparison with the existing method is assessed.

An optimised method for the proteomic profiling of full thickness human skin.

BackgroundThe skin is the largest organ of the human body and is the first line barrier defence against trauma, microbial infiltration and radiation. Skin diseases can be a result of multi-systemic disease or an isolated condition. Due to its proteolysis resistant properties there are relatively few human skin proteomic datasets published compared with other human organs or body fluids. Skin is a challenging tissue to analyse using traditional proteomic techniques due to its high lipid content, insolubility and extensive cross-linking of proteins. This can complicate the isolation and digestion of proteins for analysis using mass spectrometry techniques.ResultsWe have optimised a sample preparation procedure to improve solubilisation and mass spectral compatibility of full thickness skin samples. Using this technique, we were able to obtain data for the proteome profile of full thickness human skin using on-line two-dimensional liquid chromatography, followed by ultra-high definition label-free mass spectrometry analysis (UDMSE). We were able to identify in excess of 2000 proteins from a full thickness skin sample.ConclusionsThe adoption of on-line fractionation and optimised acquisition protocols utilising ion mobility separation (IMS) technology has significantly increased the scope for protein identifications ten-fold.Electronic supplementary materialThe online version of this article (doi:10.1186/s12575-016-0045-y) contains supplementary material, which is available to authorized users.

Synthesis of quenchers to control the fluorescence of Rhodamine B and improve the contrast ratio of blue filters for LCDs

In this study, seven quenchers (derived from either anthraquinone, phthalimidylazo, or dipyrromethene chromophores) were prepared as candidates for additives to suppress fluorescence in blue colour filters and thus improve their contrast ratio. To reduce fluorescence effectively, quenchers must have typical properties such as spectral compatibility by which the absorbance spectrum of the quencher overlaps the fluorescence emission spectrum, exhibit high molar extinction coefficients, and exert little influence on the colour of the blue filter. The seven quenchers possessed absorption maxima of approximately 570–620 nm and reduced fluorescence (by more than 24%). Those quenchers tested in filter coatings increased their contrast ratios by about 50%. They thus effectively quenched fluorescence of the blue filter but without greatly affecting the chromaticity coordinates of the filters.

A bacterial phytochrome-based optogenetic system controllable with near-infrared light.

Light-mediated control of protein-protein interactions to regulate metabolic pathways is an important approach of optogenetics. Here, we report the first optogenetic system based on a reversible light-induced binding between a bacterial phytochrome BphP1 and its natural partner PpsR2 from Rhodopseudomonas palustris bacteria. We extensively characterized the BphP1–PpsR2 interaction both in vitro and in mammalian cells, and then used it to translocate target proteins to specific cellular compartments, such as plasma membrane and nucleus. Applying this approach we achieved a light-control of cell morphology resulting in the substantial increase of cell area. We next demonstrated the light-induced gene expression with the 40-fold contrast in cultured cells, 32-fold subcutaneously and 5.7-fold in deep tissues in mice. The unique characteristics of the BphP1–PpsR2 optogenetic system are its sensitivity to 740–780 nm near-infrared light, ability to utilize an endogenous biliverdin chromophore in eukaryotes including mammals, and spectral compatibility with blue-light optogenetic systems.

Forcing Multiple Spectral Compatibility Constraints in Radar Waveforms

Radar signal design in spectrally dense environments is a very challenging and topical problem. This letter deals with the synthesis of waveforms optimizing radar performance while satisfying multiple spectral compatibility constraints. Unlike some counterparts available in the open literature, a specific control on the interference energy radiated on each shared bandwidth is enforced. To tackle the resulting NP-hard optimization problem, a polynomial computational complexity procedure based on semidefinite relaxation (SDR) and randomization is developed. Hence, some numerical results are shown to highlight the effectiveness of the new technique to devise high-performance radar waveforms complying with the spectral compatibility requirements.

Lead sulphide nanocrystal photodetector technologies

Light detection is the underlying principle of many optoelectronic systems. For decades, semiconductors including silicon carbide, silicon, indium gallium arsenide and germanium have dominated the photodetector industry. They can show excellent photosensitivity but are limited by one or more aspects, such as high production cost, high-temperature processing, flexible substrate incompatibility, limited spectral range or a requirement for cryogenic cooling for efficient operation. Recently lead sulphide (PbS) nanocrystals have emerged as one of the most promising new materials for photodetector fabrication. They offer several advantages including low-cost manufacturing, solution processability, size-tunable spectral sensitivity and flexible substrate compatibility, and they have achieved figures of merit outperforming conventional photodetectors. We review the underlying concepts, breakthroughs and remaining challenges in photodetector technologies based on PbS nanocrystals.

Luminescence efficiency of (Lu,Gd)2SiO5:Ce (LGSO:Ce) crystals under X-ray radiation

The aim of the present study was to investigate the absolute luminescence efficiency (AE) of mixed oxyorthosilicate (Lu,Gd)2SiO5:Ce (LGSO:Ce) single crystals, under X-ray irradiation. Six (Lu,Gd)2SiO5:Ce crystal samples, with dimensions of 3 × 3 × 5, 3 × 3 × 6, 3 × 3 × 10, 3 × 3 × 15, 10 × 10 × 10 and 10 × 10 × 20 mm3 were examined. The light emitted by the crystals, was evaluated by performing measurements of the AE under X-ray exposure conditions, with tube voltages ranging from 50 to 130 kV. Results were compared with previously published data for GSO:Ce and LSO:Ce crystals. The spectral compatibility of the (Lu,Gd)2SiO5:Ce crystal, with various existing optical detectors, was investigated after emission spectra measurements. Absolute efficiency was found maximum at 130 kVp for the 3 × 3 × 15 mm3 (Lu,Gd)2SiO5:Ce crystal (25.40 E.U). AE of the 10 × 10 × 10 mm3 (Lu,Gd)2SiO5:Ce crystal was found higher than both GSO:Ce and LSO:Ce crystals, in the whole X-ray tube range. The emission spectrum of (Lu,Gd)2SiO5:Ce is excellent matched with the spectral sensitivities of photocathodes and silicon photomultipliers often employed in radiation detectors. Considering the high luminescence efficiency values and the spectral compatibility with the various photodetectors, (Lu,Gd)2SiO5:Ce crystal could be considered for use in combined medical imaging detectors i.e. integrated PET/CT detectors.

A new radar waveform design algorithm with improved feasibility for spectral coexistence

Radar signal design in a spectrally crowded environment is currently a challenge due to the increasing requests for spectrum from both military sensing applications and civilian wireless services. The goal of this paper is to improve a previously devised algorithm for the synthesis of optimized radar waveforms fulfilling spectral compatibility with overlaid licensed radiators. The new technique achieves an enhanced spectral coexistence with the surrounding electromagnetic environment through a suitable modulation of the transmitted waveform energy, which was kept fixed at the maximum level in the previously devised algorithm. At the analysis stage, the waveform performance is studied in terms of trade-off among the achievable Signal to Interference Plus Noise Ratio (SINR), spectral shape, and the resulting Autocorrelation Function (ACF), also in situations where the previous technique cannot be applied.

Evaluation of Gd2O2S:Pr granular phosphor properties for X-ray mammography imaging

Phosphor materials are widely used in X-ray medical imaging detector applications, coupled with suitable photoreceptors. Upon the most demanding imaging modality is X-ray mammography, since the best defense against breast cancer is its early detection. A material suitable as a mammographic detector should efficiently absorb X-ray photons and transform them to optical photons, so as to minimize breast dose. The aim of the present study was to investigate the X-ray absorption efficiency and the absolute efficiency (AE), defined as the output optical photon power divided by the incident exposure, of Gd2O2S:Pr powder scintillator. For the purposes of this study, three scintillating screens with coating thicknesses, 34.1, 46.0 and 81.5mg/cm2 respectively, were prepared in our laboratory from Gd2O2S:Pr powder (Phosphor Technology, Ltd.) by sedimentation on silica substrates. The quantum detection efficiency (QDE), the energy absorption efficiency (EAE), the spectral matching factor and the absolute efficiency (AE) were evaluated for X-ray mammographic conditions. Furthermore theoretical models were utilized to investigate the optical photon transmission properties through the phosphor mass. Gd2O2S:Pr presented high X-ray absorption properties and good spectral compatibility with several photoreceptors. It may be utilized for X-ray mammographic imaging if it is put in conjunction with a sensitive photoreceptor, so as to enhance Gd2O2S:Pr light emission properties.

Ground Motion Record Selection Based on Broadband Spectral Compatibility

The increasing interest in performance-based earthquake engineering has promoted research on the improvement of hazard-consistent seismic input definition and on advanced criteria for strong motion record selection to perform nonlinear time history analyses. Within the ongoing research activities to improve the representation of seismic actions and to develop tools as a support for engineering practice, this study addresses the selection of displacement-spectrum-compatible real ground motions, with special reference to Italy. This involved (1) the definition of specific target displacement spectra for Italian sites, constrained—both at long and short periods—by results of probabilistic seismic hazard analyses; (2) the compilation of a high-quality strong ground motion database; and (3) the development of a software tool for computer-aided displacement-based record selection. Application examples show that sets of unscaled, or lightly scaled, accelerograms with limited record-to-record spectral variability can also easily be obtained when a broadband spectral compatibility is required.

Automatic standardization method for Raman spectrometers with applications to pharmaceuticals

An effective and practical method, based on automatic peak detection, Lorentzian fitting, and polynomial fitting, is developed for aligning spectra, which can significantly reduce or eliminate systematic differences between Raman spectrometers. In this work, Lorentzian fitting of the experimental spectra is performed to precisely locate the peak positions. Then the standardization procedure is illustrated on the spectra of a chemical standard measured on primary and secondary instruments, and the spectra can be successfully aligned to each other after shift correction. It is shown that the similarity of pharmaceutical spectra acquired on three Raman spectrometers is then considerably improved after removal of the Raman shift difference. The result shows that the similarity of the spectra between primary and secondary spectrometers increases dramatically from about 0.8 to 0.95 after spectra standardization. This means that the proposed standardization method can effectively reduce or eliminate systematical errors and enhance spectral compatibility across different instruments. Copyright © 2014 John Wiley & Sons, Ltd.

Measurement of the luminescence properties of Gd2O2S:Pr,Ce,F powder scintillators under X-ray radiation

The aim of the present study was to investigate the absolute luminescence efficiency of gadolinium oxysulfide powder scintillators, doped with praseodymium, cerium and fluorine (Gd2O2S:Pr,Ce,F). Gd2O2S:Pr,Ce,F is a non-hygroscopic material, emitting green light with short decay time. For the purposes of this study, two scintillating screens with coating thicknesses 35.7 and 71.2 mg/cm2, were prepared in our laboratory from Gd2O2S:Pr,Ce,F powder (Phosphor Technology, Ltd) by sedimentation on silica substrates. The light emitted by the phosphors under investigation was evaluated by performing measurements of the absolute efficiency under X-ray exposure conditions with tube voltages ranging from 50 to 130 kV. Results were compared with previously published data for Gd2O2S:Eu screens. The spectral compatibility of Gd2O2S:Pr,Ce,F with various existing optical detectors, was investigated after emission spectra measurements. Particle size and morphology parameters of the Gd2O2S:Pr,Ce,F powder phosphor were verified via scanning electron microscope (SEM) micrographs. Absolute efficiency was found to maximize at 60 kVp for the 71.2 mg/cm2 and at 90 kVp for the 35.7 mg/cm2 Gd2O2S:Pr,Ce,F screens. Absolute efficiency of the 71.2 mg/cm2 Gd2O2S:Pr,Ce,F screen was higher in the whole X-ray tube voltage range showing potential interest for non-CT medical imaging (i.e. dental radiology) or industrial digital radiography.

Selection of spectrum- and seismo-compatible accelerograms for the Tuscany region in Central Italy

This article illustrates the results of a study aimed at developing a methodology for the automatic identification of the seismic input at outcropping rock sites and flat topographic conditions necessary to carry out non-linear dynamic analysis of structures and geotechnical systems. The seismic input is provided in terms of a set of 7 natural accelerograms recorded on outcropping rock and satisfying the average spectral compatibility requirements prescribed by the Italian seismic code (NTC08).The study focuses on the territory encompassing Tuscany region in Central Italy and it has been carried out for six return periods, which are 50, 75, 101, 475, 712 and 949 years. The procedure involved four main steps: (1) grouping of the response spectra with similar features; (2) definition of the reference response spectrum for each group; (3) selection of spectrum-compatible accelerograms using the reference response spectrum of each group; and (4) linear scaling of the accelerograms to satisfy the compatibility requirement with respect to other response spectra of the group. The last step is implemented through an interactive, user-friendly program named SCALCONA 2.0, which provides the seismic input in agreement with the site location and return period specified by the user. The program is freely available at the following web site: http://www.rete.toscana.it/sett/pta/sismica/01informazione/banchedati/input_sismici/progettazione/index.htm.

Radar waveform design in a spectrally crowded environment via nonconvex quadratic optimization

Radar signal design in a spectrally crowded environment is a very challenging and topical problem due to the increasing demand for both military surveillance/remote-sensing capabilities and civilian wireless services. This paper deals with the synthesis of optimized radar waveforms ensuring spectral compatibility with the overlayed licensed electromagnetic radiators. A priori information, for instance, provided by a radio environmental map (REM), is exploited to force a spectral constraint on the radar waveform, which is thus the result of a constrained optimization process aimed at improving some radar performances (such as detection, sidelobes, resolution, tracking). The feasibility of the waveform optimization problem is extensively studied, and a solution technique leading to an optimal waveform is proposed. The procedure requires the relaxation of the original problem into a convex optimization problem and involves a polynomial computational complexity. At the analysis stage, the waveform performance is studied in terms of trade-off among the achievable signal to interference plus noise ratio (SINR), spectral shape, and the resulting autocorrelation function (ACF).

On the response of GdAlO3:Ce powder scintillators

The aim of the present study was to investigate the luminescence efficiency (XLE) of gadolinium aluminum perovskite (GdAlO3:Ce) powder scintillator. This powder phosphor, also known as GAP:Ce scintillator, is a non-hygroscopic material, emitting blue light with short decay time. For the purposes of this study, five scintillating screens with coating thicknesses, 14.7, 31.0, 53.7, 67.2 and 121.1mg/cm2, were prepared in our laboratory from GdAlO3:Ce powder (Phosphor Technology, Ltd) by sedimentation on silica substrates. The light emitted by the phosphors under investigation was evaluated by performing measurements of the absolute luminescence efficiency (AE), X-ray luminescence efficiency and detector quantum gain (DQG) under X-ray exposure conditions with tube voltages ranging from 50 to 140kV. The quantum detection efficiency (QDE) and energy absorption efficiency (EAE) were also evaluated. The spectral compatibility of GdAlO3:Ce, with various existing optical detectors, was investigated after emission spectra measurements. A theoretical model, describing radiation and light transfer, was used to fit experimental AE data. This has allowed the estimation of optical attenuation coefficients of the scintillator. GdAlO3:Ce exhibited higher QDE and EAE values, compared to aluminium perovskite (YAlO3:Ce) but lower absolute efficiency values. Absolute efficiency was found to increase with increasing X-ray tube voltage, although for values higher than 120kVp a decrease was observed.

Studying the luminescence efficiency of Lu2O3:Eu nanophosphor material for digital X-ray imaging applications

Scintillator materials are widely used in X-ray medical imaging detector applications, coupled with available photoreceptors like radiographic film or photoreceptors suitable for digital imaging like a-Si, charge-coupled devises (CCD), complementary metal-oxide-semiconductors (CMOS) and GaAs). In addition, scintillators can be utilized in non-medical imaging detectors such as industrial detectors for non-destructive testing (NDT) and detectors used for security purposes (i.e. airport luggage control). Image quality and dose burden in the above applications is associated with the amount of optical photons escaping the scintillator as well as the amount of optical photons captured by the photoreceptor. The former is characterized by the scintillator efficiency and the latter by the spectral matching between the emission spectrum of the scintillator and the spectral response of the photoreceptor. Recently, a scintillator material, europium-activated lutetium oxide (Lu2O3:Eu), has shown improved scintillating properties. Lu2O3:Eu samples of compact nanocrystalline non-agglomerated powder were developed in our laboratory using homogeneous precipitation from a water-toluene solution in the presence of polyvinyl alcohol as a surfactant. In order to test their light-emission properties, experimental measurements under the excitation of X-ray spectra with X-ray tube voltages between 50 kVp and 140 kVp were performed. This range of applied voltages is appropriate for X-ray radiology, NDT and security applications. Lu2O3:Eu was evaluated with respect to output yield and spectral compatibility of digital imaging photoreceptors (CCD-based, CMOS-based, amorphous silicon a:Si flat panels, ES20 and GaAs). High light yield and spectral compatibility increase the performance of the medical detector and reduce the dose burden to the personnel involved. In addition a theoretical model was used to determine the values for the Lu2O3:Eu optical photon light propagation parameters. The inverse diffusion length was found to be equal to 33 cm2/g. In addition Lu2O3:Eu was found to match well with several photoreceptors capable of digital imaging (i.e. GaAs).

Evaluation of the Red Emitting ${\rm Gd}_{2}{\rm O}_{2}{\rm S}\!\!:\!\!{\rm Eu}$ Powder Scintillator for Use in Indirect X-Ray Digital Mammography Detectors

The aim of the present study was to investigate the imaging transfer characteristics and the luminescence efficiency (XLE) of Gd2O2S:Eu powder scintillator for use in X-ray mammography detectors. Gd2O2S:Eu emits in the red part of the visible spectrum, having very good spectral compatibility with optical sensors employed in digital imaging systems. Three Gd2O2S:Eu powder scintillating screens, with coating thicknesses 33.1, 46.4 and 63.1 mg/cm2 , were prepared in our laboratory. The imaging performance of these screens was assessed by experimental determination of the modulation transfer function (MTF), the noise transfer function (NTF) and the detective quantum efficiency (DQE) as well as a single index image quality parameter such as the information capacity (IC). A theoretical model, describing radiation and light transfer, was used to fit experimental MTF data. This has allowed the estimation of optical attenuation coefficients of the scintillator. In addition, a previously validated Monte Carlo code, based on the X-ray attenuation properties and on the Mie light scattering theory, was used to estimate the X-ray detection efficiency, the Swank factor and the zero frequency DQE of the Gd2O2S:Eu scintillator. Results showed that Gd2O2S:Eu exhibits high MTF and DQE values, which are comparable to those of a commercially employed Gd2O2S:Tb screen. In addition Gd2O2S:Eu shows high compatibility (effective gain) to CCDs and to recently introduced CMOS based detectors. Considering our image quality parameters and luminescence efficiency results, this material can potentially be considered for use in digital X-ray mammography detectors.

Spectral shape-based assessment of SDOF nonlinear response to real, adjusted and artificial accelerograms

The simple study discussed in this paper compared different procedures to obtain sets of spectral matching accelerograms for nonlinear dynamic analysis of structures in terms of inelastic seismic response. Six classes of records were considered: original (unscaled) real records, real records moderately linearly scaled, real records significantly linearly scaled, real records adjusted by wavelets, and artificial accelerograms generated by two different procedures. The study is spectral shape-based; that is, all the considered sets of records, generated or selected, match individually (artificial and adjusted) or on average (real records) the same design spectrum for a case-study site in Italy. This is because spectral compatibility is the main criterion required for seismic input by international codes. Three kinds of single degree of freedom (SDOF) system, non-degrading and non-evolutionary, non-degrading and evolutionary, and both degrading and evolutionary, were used to evaluate the nonlinear response to the compared records. Demand spectra in term of peak and cyclic responses were derived for different strength reduction factors. Results of the analysis show that artificial or adjusted accelerograms may underestimate, in some cases, and at high nonlinearity levels, the displacement response, if compared to original real records, which are considered as a benchmark herein. However, this conclusion does not seem to be statistically significant. Conversely, if the cyclic response is considered, artificial record classes show a significant overestimation of the demand, which does not show up for wavelet-adjusted records. The two classes of linearly scaled records do not show systematic bias with respect to those unscaled for both types of response considered, which seems to confirm that amplitude scaling is a legitimate practice.

Evaluation of the Luminescence Efficiency of YAG:Ce Powder Scintillating Screens for Use in Digital Mammography Detectors

In the present study scintillating screens prepared from Y3Al5O12:Ce (YAG:Ce) powder phosphor were evaluated for use in digital mammography. YAG:Ce has never previously been used in X-ray medical imaging, however since it emits green light (i.e peak at 550 nm), it is expected to match well the spectral sensitivities of most photodetectors (photodiodes, CCDs and amorphous silicon sensors) incorporated in various digital mammography detectors. YAG:Ce was purchased in powder form and was used in order to prepare test screens in the laboratory. Screens were evaluated by determining the quantum detection efficiency (QDE), the energy absorption efficiency (EAE), the absolute luminescence efficiency, the X-ray luminescence efficiency (XLE), the light emission spectrum, the X-ray to light intrinsic conversion efficiency and the spectral compatibility with various photodetectors. Results were compared with phosphor materials commercially employed in X-ray imaging such as CsI:Tl and Gd2O2 S:Tb. Maximum YAG:Ce emission efficiency was observed for the 63 mg/cm2 screen at 49 kVp. The spectral compatibility with amorphous silicon photodiodes (0.93) and CCDs (0.95) was found to be very high, better than the corresponding compatibility of the CsI:Tl screen, mostly used in current digital radiography detectors. Taking into account the YAG:Ce overall performance, its short decay time as well as its spectral compatibility with amorphous silicon detectors and CCDs, YAG:Ce could be of interest for further investigation for applications in digital mammography.