Specific Intervals Research Articles

Social Interoception and Autonomic System Reactivity during Synchronization Behavior.

Within the social interoception field, little is known about the impact of interoception on autonomic system reactivity during synchronization tasks. The impact of social framing manipulation and Interoceptive Attentiveness (IA; defined as concentrated attention on the breath for a specific time interval) on autonomic responses during interpersonal synchronization was investigated in this research. Under two experimental interoceptive conditions-the concentration and no focus on the breath condition-participants completed two synchronization tasks. A social framing was given to participants by informing them that they needed to complete the tasks in unison to improve their collaboration abilities. Autonomic responses (electrodermal activity and cardiovascular indices) were collected throughout task performance. Two orders of results were observed: high cognitive engagement was detected during the focus on the breath condition and for the social frame. This effect was specifically observed for the motor compared to the linguistic synchronization task. Meanwhile, a potential lack of emotional control was observed in the no focus on the breath condition when the synchronization tasks were not socially framed. Such results encourage the use of the hyperscanning paradigm to deepen the impact of IA in real-time and ecological interpersonal synchronization dynamics.

Post-rifting uplift and inversion of an intra-plate basin: The Doseo basin, Central Africa

There is a growing recognition that the post-rifting phase of basin evolution is far from being tectonically quiescent, as it can involve episodic uplift. However, the dynamic mechanisms responsible for this phenomenon remain a subject of controversy, particularly for intra-plate basins situated distant from active plate boundaries. Accurately determining the timing and magnitude of uplift is essential for elucidating the driving model behind these processes. In this study, we document the thermal history of the Doseo basin within the West and Central Africa Rift System (WCARS) using a combination of apatite fission track analysis and vitrinite reflectance data. Our findings reveal a period of accelerated exhumation during the late Eocene to Miocene epoch (∼45-20 Ma), characterized by kilometer-scale uplift, which corresponds to the formation of angular unconformities, folds, and fault-related anticlines. This specific time interval appears to be critical for the Cenozoic petroleum system, coinciding with the peak maturation of source rocks and the simultaneous formation of compressional traps. When integrated with the seismic data and previously published thermochronological data, our research reveals two significant cooling and uplift events in WCARS: a Santonian extrusion event and a late Eocene exhumation event. Both of these events have the potential to impact the entire tectonic plate, and Tethys realm. Furthermore, this two-stage exhumation event aligns closely with the timing of the Africa-Europe convergence collision. Consequently, we come to conclude that far-field lateral compression emerges as the dominant driving mechanism for intra-plate uplift, outweighing the influence of the mantle model.

Comparison of the Effect of Ondansetron and Dexamethasone on Postoperative Shivering After Cesarean Section in Patients Undergoing Spinal Anesthesia

Background: Shivering is one of the most common problems after spinal anesthesia, which can cause many complications. Various methods and drugs have been used to prevent and treat postoperative shivering. In the present study, the pretreatment effect of ondansetron and dexamethasone in reducing the incidence of shivering after elective caesarean section by the spinal method has been investigated. Methods: In this study, 78 patients undergoing elective cesarean surgery who were eligible to enter the study were evaluated and randomly divided into two groups: 8mg of ondansetron and 4mg of dexamethasone 15 minutes before the end of surgery. Then, the incidence of shivering was measured at specific time intervals after surgery. Statistical analysis was done using SPSS software. Results: The two groups were similar in terms of age, height, weight, and BMI (p-value > 0.05). The incidence of shivering at the time of entering the recovery, 10, 20, and 30 minutes in the ondansetron group was 23.1%, 20.5%, 12.8% and 0% and in the dexamethasone, group was 20.5%, 15.4%, 5.2% and 0%, respectively. Statistical analysis showed that these differences are not significant at the significance level of 0.05. These two drugs have the same effectiveness in controlling shivering after cesarean section under spinal anesthesia (p-value > 0.05). Conclusion: Dexamethasone and ondansetron will be able to control shivering after caesarean section with spinal anesthesia.

The impact of submucosal PRP injection on wound healing after endoscopic sinus surgery: a randomized clinical trial

PurposeChronic rhinosinusitis (CRS) is a prevalent chronic disease observed on a global scale. The utilization of endoscopic sinus surgery (ESS) has gained significant recognition as an effective intervention for individuals with CRS and nasal polyps who have not responded to conventional treatments. The need (or not) for revision surgery frequently relies on the promotion of optimal wound healing. The impact of platelet-rich plasma (PRP) on tissue healing has been extensively examined in various surgical fields.MethodsThe present prospective study involved 30 patients suffering with nasal polyposis who underwent endoscopic sinus surgery. 15 patients were assigned to the PRP group, and 15 patients to the control group. The clinical follow-up of the patients took place at specific intervals, at weeks 1, 2, 3, 4, 8, and 12 after the surgical procedure. The evaluator identified the existence of adhesions, crusting, bleeding, granulation and infection using a visual analogue scale score. The patients also completed the SNOT 22 questionnaire prior to surgery and at each postoperative visit.ResultsThe present study observed a lower incidence of adhesion, infection, hemorrhage and granulation in the PRP group. Furthermore, a statistically significant difference was detected between the groups.ConclusionBased on the findings of the present investigation, it seems that platelet-rich plasma (PRP) is beneficial on wound healing during the early stages following the surgical procedure. The technique is characterized by its limited invasiveness, which contributes to its low risk profile and the achievement of clinically good outcomes.

Time-based prospective memory in preschoolers - the role of time monitoring behavior.

Time-based prospective memory (TBPM) refers to the ability to remember to perform an intended activity at a specific time in the future or after a specific time interval. This article reviews TBPM memory in preschool children and explores the role of time monitoring behavior in TBPM performance. A total of 242 preschool-aged children (aged 2-6) performed a prospective memory task, wherein prospective memory accuracy, ongoing task performance, and time monitoring activity were assessed. Additionally, the study examined the relationship of various cognitive abilities to TBPM performance through the use of appropriate cognitive tasks. The first signs of TBPM were observed in children as young as 2 years old. No significant age differences were identified; preschoolers can perform a delayed intention on their own initiative at a certain point in the future only to a minimal extent. The majority of variance in TBPM performance could be explained by time checking behavior. The current study indicated that even 2-year-olds can perform TBPM at a basic level when the task is sufficiently understandable. While many cognitive abilities are correlated with TBPM performance, it appears that only time checking behavior plays a significant role in TBPM among preschoolers.

Development of Analytical Profile of Ocimum sanctum L. leaves Powder prepared by Classical and Lyophilization method through Accelerated Stability Studies

Shelf life means the time period during which the potency of a drug remains unaffected from environmental factors or microbial contamination. Nowadays diverse procedures of making powder are available which affect on shelf life of them. Ocimum sanctum L. is most common household herb in Indian subcontinent. Hence, the present study is aimed to develop analytical profile of Ocimum sanctum L. leaves powder by classical and lyophilized method and compare the stability of both the samples. Materials and Methods: Ocimum sanctum L. leaves powder was prepared by two different drying methods and accelerated stability study was conducted as per ICH guideline Q1A (R2). Physicochemical analysis was repeated at interval of 0, 1, 3 and 6 months. Organoleptic parameters, microbial limits and heavy-metal analysis were observed at specific intervals. Result and Discussion: No significant changes were observed in organoleptic characters of both the samples up to storage of 6 months at accelerated condition. The values of physicochemical parameters of both the samples were within the prescribed limit specified in Ayurvedic Pharmacopeia of India. Results of Microbiological limit test were also below the limit and considerably decreased at specific intervals. Heavy metals namely arsenic, cadmium and mercury were not detected and lead was present below detectable limits. Conclusion: Analysis revealed that the classically prepared powder has better shelf life (3.08 years) than lyophilized powder (2.70 years) and also provides the modest and effective ways for optimal Eugenol extraction in accelerated conditions.

Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial.

Sinus augmentation procedures have become a valuable solution for patients with posterior maxillary edentulism. The objective of this study was to explore the efficacy and safety of porcine xenograft with collagen supplementation as a potential alternative to autologous bone grafts in lateral sinus augmentation over a three-year follow-up period. Twelve patients, each with bilateral posterior maxillary edentulism, were enrolled and randomly allocated to receive either a porcine xenograft or an autologous graft. Comprehensive assessments, including clinical and radiographic evaluations, were conducted at specific intervals, including implant stability, marginal bone loss, prosthetic and biological complications, and patient preferences. The results demonstrated no significant differences between the two graft materials in terms of implant survival, marginal bone loss, and patient preferences after three years of follow-up. Only one implant was affected by peri-implantitis, and prosthesis-related complications were present in one patient possibly due to bruxism. In conclusion, these findings suggest that a porcine xenograft with collagen supplementation may be a viable alternative to an autograft in lateral sinus augmentation procedures. The high implant survival rate, minimal complications, and patient satisfaction indicate the potential clinical relevance of this graft material and should be further investigated to confirm these promising results.

Performance evaluation of high-rise buildings using database-assisted design approach

In recent years, performance-based design (PBD) has gained attention and is sought to be the benchmark approach in the field of wind engineering. While the concept of performance-based design is well-accepted in earthquake engineering, it is yet to be embraced for the design of buildings to resist severe wind loads. This paper introduces a framework for the performance-based wind design (PBWD) of tall steel buildings using a time domain analysis that keeps the process of wind effects and the structural design process integrated, transparent, and fully auditable. From the perspective of PBWD, the main objective is to achieve a desirable performance level for a given hazard level, i.e., mean recurrence interval of extreme wind. The wind effects are directly related to the mean annual return of wind through a well-accepted simulation approach. A 180 m tall standard CAARC building is used for the case study to illustrate the proposed methodology. The wind load time histories are determined using the pressure tap data on exterior faces of the building measured in the wind tunnel. With the calculated wind loads, nonlinear dynamic analysis is conducted with various wind directions and mean wind speeds based on database-assisted design (DAD) approach. The key performance measures such as demand-to-capacity indices, inter-story drift, damage deformation index, and floor accelerations are calculated as a function of wind directions and mean wind speed. The obtained responses are used in conjunction with a local wind climatological database to determine the extreme wind effects for any specific mean recurrence interval. The performance of the steel building is evaluated for three performance criteria, including occupant comfort, operational, and continuous occupancy. The conducted performance assessment reveals that building fails to satisfy the serviceability requirement of drifts. However, the building satisfies the requirements for the occupant comfort and operational performance levels for strength design, while it also satisfies the continuous occupancy, limited interruption in Risk category II. The result reveals that the proposed framework provides realistic assessment of performance of the building incorporating the wind directionality and return period of the wind speeds.

Electric and Magnetic Fields Analysis of the Safety Distance for UAV Inspection around Extra-High Voltage Transmission Lines

The deployment of small unmanned aerial vehicles (UAVs), or drones, for transmission line inspections, has brought attention to the potential impact of electromagnetic fields (EMFs) on UAV operations. This work describes a mathematical model based on the finite elements method (FEM), designed to examine the electric and magnetic fields produced by extra-high voltage (EHV) conductors. The current study extends the analysis to encompass both electric and magnetic fields and evaluates the safe distances for UAVs operating near 345 kV, 500 kV, and 765 kV transmission lines. The electromagnetic environment around these EHV transmission lines was simulated using electrostatic, magnetostatic, and transient magnetic modules within the QuickField software 6.6. Electric and magnetic profiles were estimated using 2D finite element analysis, including a numerical simulation for phase-to-phase fault EMFs for the above transmission lines. These results were then cross-verified with theoretical calculations at specific intervals and further validated using the EMFACDC analytical method developed by the International Telecommunication Union. This comprehensive assessment concludes that precise distance considerations are necessary to ensure UAV safety during power line inspections, mitigating potential risks from EMF interference.

Potential benefits of climate change on navigation in the northern sea route by 2050

Climate change has been inducing a continuous increase in temperatures within the Arctic region, consequently leading to an escalation in the rates of Arctic ice depletion. These changes have profound implications for navigation along the Arctic Northern Sea Route (NSR). However, access to the NSR is constrained to specific temporal intervals when the sea ice thickness reaches a threshold that permits safe passage of ships. This research employs climate change model simulations and the Polar Operational Limit Assessment Risk Indexing System framework to investigate the navigational feasibility of diverse ship types along NSR during the calendar years 2030, 2040, and 2050, under SSP2-4.5 and SSP5-8.5 scenarios. Different ship categories were analyzed within the context of these two scenarios. Results indicate considerable variation in the navigability of different ship categories across different scenarios and years. In general, polar ships demonstrate a higher navigational potential throughout most of the year, while pleasure crafts are constrained to specific periods. These findings bear significant implications for the future of shipping along the NSR. As Arctic ice continues to melt, NSR is anticipated to become more accessible to ships, albeit with navigational availability remaining contingent on the ship category and seasonal considerations.

Automated hematological cell count using sysmex XN-1000V in Testudo hermanni: Agreement with manual count

Mediterranean area represents the main habitat of Testudo hermanni. Clinical signs of disease of these tortoises are non-specific, making the hematology results crucial in revealing underlying pathological conditions. However, accurate automated identification of blood cell populations is hampered by the presence of nucleated erythrocytes (NRBC) and thrombocytes (Thr), necessitating manual methods such as counting chambers. The aim of the study was to assess the performance of the novel automated hematology analyzer Sysmex XN-1000 V, which includes a a specific channel (WNR) for counting NRBC, in accurately identify and quantify the different blood cell populations of Testudo hermanni. Additionally, its agreement with manual counts was evaluated. Fifty heparinized blood samples were initially counted using the Neubauer improved chamber and then analysed twice with Sysmex XN-1000 V. Thirteen out of 50 samples were instrumentally counted again after 48 h to assess the inter-assay precision. All WNR scattergrams were re-analysed using an ad hoc gate panel to differentiate two populations: NRBCs (weak fluorescence signal) and WBC + Thr (high fluorescence signal). Sysmex XN-1000 V demonstrated optimal intra- and inter-assay precision for NRBCs (CV 0.98% ± 1.96; 1.31% ± 2.98) and moderate precision for WBC + Thr (CV 9.24% ± 16.61; 12.69% ± 10.35). No proportional nor constant errors were observed between the methods for both the populations. The instrumental NRBC counts were consistently slightly lower, while WBC + Thr counts were slightly higher compared to manual counts. These findings suggest that Sysmex XN-1000 V can be used for analyzing cell populations in heparinized blood of Testudo hermanni. However, specific instrumental reference intervals are suggested.

Where To Go at the Next Timestamp

The next Point of Interest (POI) recommendation is the core technology of smart city. Current state-of-the-art models attempt to improve the accuracy of the next POI recommendation by incorporating temporal and spatial intervals or by partitioning the POI coordinates into grids. However, they all overlook a detail that in real life, people always want to know where to go at an exact time point or after a specific time interval instead of aimlessly asking where to go next. Moreover, due to individual preferences, different users may visit different places at the same timestamp. Therefore, utilizing timestamp queries can enhance the personalized recommendation capability of the model and mitigate overfitting risks. These implies that using timestamp can achieve more precise recommendations. To the best of our knowledge, we are the first to use the next timestamp for next POI recommendation. In particular, we propose a Time-Stamp Cross Attention Network (TSCAN). TSCAN is a two-layer cross-attention network. The first layer, Time Stamp Cross Attention Block (TSCAB), uses cross-attention between the next timestamp and historical timestamps, and multiplies the attention scores on corresponding POI to predict the next POI that is most related to the history. The other layer, Cross Time Interval Aware Block (CTIAB), applies the time intervals between the next timestamp and historical timestamps to the POI obtained by TSCAB and historical POIs, allowing temporally adjacent POIs to have a greater similarity. Our model not only has a significant improvement in accuracy but also achieves the goal of personalized recommendation, effectively alleviating overfitting. We evaluate the proposed model with three real-world LBSN datasets, and show that TSCAN outperforms the state-of-the-art next POI recommendation models by 5~9%. TSCAN can not only recommend the next POI, but also recommend the possible POI to visit at any specific timestamp in the future.

Evaluation of Macular Neurovasculature and Choroidal Blood Flow Following Inferior Oblique Myectomy Using Optical Coherence Tomography Angiography.

To evaluate the short-term effects of inferior oblique myectomy on the retinal neurovasculature, choroidal thickness, and choroidal vascularity index at the macula. Patients older than 5 years who were candidates for inferior oblique muscle myectomy surgery participated in the study. Patients with any systemic or ocular disease that could affect the macular neurovasculature were not included in the study. After recording demographic data, including age and gender, and conducting a complete ophthalmic examination, macular optical coherence tomography (OCT), enhanced depth imaging OCT, and OCT angiography imaging (AngioVue software (V.2017.1.0.151; Optovue, Inc) were performed before (1 day to 1 week) and in the specific time intervals (1 week, 1 month, and 3 months) after the surgery for all participants. Eighteen patients (13 male and 5 female) who underwent inferior oblique muscle myectomy, with a mean ± standard deviation age of 24.22 ± 18.14 years, were included in this study. The baseline mean ± standard deviation of subfoveal choroidal luminal area and subfoveal total choroidal area were 0.390 ± 0.03 and 0.539 ± 0.04 mm2, respectively. The changing pattern of the subfoveal choroidal vascularity index and subfoveal choroidal luminal area was statistically significant (P = .013 and .035, respectively). Inferior oblique myectomy can lead to changes in choroid hemodynamics in the short term. However, these changes seem to be temporary. [J Pediatr Ophthalmol Strabismus. 2024;61(4):235-244.].

Dynamic neighbours: a proposal of a tool to characterize phase transitions

For molecular dynamics simulations of hard particles, we define dynamic neighbours as the distinct particles that collide with a given reference one during a specific time interval. This definition allows us to determine the distribution of the number of dynamic neighbours, its average, and its standard deviation. We will show that regardless of the time window used to identify dynamic neighbours, their distribution is correlated with diffusion coefficients, structure, and configurational entropy. Thus, it is likely that the distribution of the number of dynamic neighbours may be employed as another tool to gain insights into the dynamic behaviour of hard-core systems. We tested this approach on 2D and 3D systems consisting of monodisperse and binary mixtures of hard disks and spheres. Results show that implementing dynamic neighbours to define order parameters can sharpen the signals where transitions take place.

Let Us Manage BP Monitor Data Using WordPress Server and C#

Purpose: Nowadays, due to our unhealthy lifestyle, hypertension is a common and serious issue. We visit the doctor for a regular checkup at specific intervals. The doctor asks for a record of BP to review the medicine. Generally, we write our BP records on paper and carry them to show the doctor. There are a couple of disadvantages in this procedure. At first, most of the time, we did not find our paper at the time of the doctor's visit. Sometimes, the doctor is not able to read the handwriting. The doctor needs more time to estimate the high, low, and average BP record till the last visit. Sometimes, doctors prefer the BP curve. However, this procedure is more challenging. If any one of the events does not happen as expected, the treatment might go wrong. We need a good solution for the above all. We have the strength of various matured technologies. Applying those, we can solve the above situation quickly. Design/Methodology/Approach: Now, the solution is to record our BP data electronically rather than handwritten so that doctors can understand it easily. To store the bp data, we use a database. We will use a cloud database so that it can be accessible from anywhere. We can use a PC or mobile application to enter the BP data. We must enter the current reading whenever we measure BP using the apps. That is it. The application does the rest of the process. Findings/Result: As we describe, the procedure is primarily hectic. To enter bp data by opening is a time-consuming task. However, once familiar to us, it has excellent benefits. Once they adopt it, it will become a user-friendly tool to manage the BP data. Originality/Value: Several procedures are available to store and display the BP record. The smartwatch is a generic device that stores the data inside the application and then displays it according to our needs. However, it has serious drawbacks; in some ranges ( as observed in the high range), it does not provide an accurate value. Here, we are capturing the bp data from a dedicated bp instrument, which we can consider a reliable data source. Our application aims to provide as accurate data as possible to the doctors who need information. So, the application provides actual value to the user. Paper Type: Conceptual Research.

Transient responses of double core-holes generation in all-attosecond pump-probe spectroscopy

Double core-holes (DCHs) show remarkable and sensitive effects for understanding electron correlations and coherence. With advanced modulation of x-ray free-electron laser (XFEL) facility, we propose the forthcoming all-attosecond XFEL pump-probe spectroscopy can decipher the hidden photon-initiated dynamics of DCHs. The benchmark case of neon is investigated, and norm-nonconserving Monte-Carlo wavefunction method simulates non-Hermitian dynamics among vast states, which shows superiority in efficiency and reliability. In our scheme, population transfer to DCHs is sequentially irradiated by pump and probe laser. By varying time delay, Stark shifts and quantum path interference of resonant lines sensitively emerge at specific interval of two pulses. These ubiquitous multi-channel effects are also observed in phase-fluctuating pulses, derived from extra phases of impulsive Raman processes by pump laser. Non-perturbation absorption/emission verifies the uniquely interchangeable role of two pules in higher intensity. Our results reveal sensitive and robust responses on pulse parameters, which show potential capacity for XFEL attosecond pulse diagnosis and further attosecond-timescale chemical analysis.

Design and development of high-dose bioactive oil-loaded transdermal patch with the aid of natural waste as an adsorbent- optimization with SeDeM-SLA tool

PurposeRheumatoid arthritis (RA) is an autoimmune disease that affects joints significantly. Its prevalence varies globally, with more impact on females than males. Presently it is treated using NSAIDs which unfortunately show significant adverse effects on the liver and renal system after long-term use. Conventional topical use of bioactive oils like ginseng oil is one of the best natural options to treat RA, but poor retention time has limited its usefulness. By considering the involvement of ginseng oil in managing RA and the associated limitations, the proposed study investigated the impact of the transdermal patch prepared by ginseng oil loaded-natural biocompatible adsorbent in treating RA. MethodAt early stage of research, the flow property of ginseng oil-loaded adsorbent was optimized by using advanced technology, viz. Brookfield powder flow tester and SeDeM model. In the lateral stage, the transdermal patches of oil-loaded adsorbent were prepared by variable concentrations of HPMC and PEG using the solvent casting method. Prepared patches were evaluated for various parameters. ResultOptimized patch showed average thickness, average weight, folding endurance, tensile strength, and moisture content as 0.38 ± 0.10 mm, 0.215 ± 0.41 gm/ 2 sq. inch, 145 ± 0.20, 3.370 ± 0.16 MPA/mm and 3.770 ± 0.81 %, respectively, along with satisfactory skin adherence property. In vitro diffusion study showed increased ginseng oil release from the prepared patch at a specific interval of up to 10 h, and then release diminished. ConclusionAnti-inflammatory test and measurement of cytokines levels (IL-6 and TNF-α) on male Wistar rats showed a significant reduction in paw edema and notable control on the cytokines level compared to a conventional approach.

Inter-discharge optimization for fast, reliable access to ASDEX Upgrade advanced tokamak scenario

Rapid inter-discharge simulation and optimization using the RAPTOR code have allowed the development of a reliable and reproducible early heating strategy for an advanced tokamak (AT) scenario on ASDEX Upgrade. Solving for electron heat and current diffusion in RAPTOR with ad-hoc formulas for heat transport and electron cyclotron current drive (ECCD) efficiency is found to robustly recover the coupled dynamics of Te and q, while maintaining model parameters fixed for all discharges. The pedestal top boundary condition in pre-shot simulations is set by a newly derived scaling law for the electron pressure at ρ = 0.8, using a data set of previous AT discharges. RAPTOR simulations have allowed to develop an understanding of the onset of 3/2 tearing modes, which were observed to have a detrimental impact on confinement when low magnetic shear conditions are present at the rational surface during the high-β phase. Delaying the NBI heating, by a specific time interval found via simulations, has led to avoiding these modes. A non-linear optimization scheme has been applied to optimize the ECCD deposition radii to reach a stationary state with qmin>1 at the beginning of the flat-top phase, while ensuring a non-zero magnetic shear at q = 1.5 throughout the high-β phase, and has been successfully tested in experiment. However, further experiments, aiming for qmin>1.5 , have highlighted limitations of the present feedforward control approach in the presence of shot-to-shot variations that are not included in the applied model. Application of real-time model-based control is proposed to overcome model-reality mismatches in future work.

Effect of Beverage Solutions on Surface Roughness of PEEK CAD –CAM, 3D Printing Denture Base and Heat Cure Acrylic Resin Denture Base Materials

The Aim: The aim of this research was to investigate how distilled water, tea, coffee, and cola affected the surface roughness of poly ether ether ketone CAD-CAM, 3D printing, and heat cure acrylic resin denture bases at specific intervals (6 ,12days). Materials and Methods: Disk shape 10 mm (diameter) ×2 m m (thickness), manufactured from materials used which were PEEK, 3D printing and heat cure acrylic resin. Total number of samples are n= (75) samples, control samples not immersed in beverage media n= 15, experimental samples immersed in beverage solutions (distilled water, tea, coffee and cola) n=60 for evaluating the surface roughness at (6, 12 and 24 days) .Then all collecting data were statically analyzed by spss v ersion 25, by means of descriptive statistics, analysis of variance (ANOVA) and duncan multiple range tests at p ≤ 0.05. The Results: The results revealed a significant increase in surface roughness in all beverage solutions at p ≤ 0.0 5. Conclusions: All beverage solutions had a negative effect on surface roughness of all experimental materials, the surface roughness increased. cola had the most aggressive effect followed by coffee then tea and distilled water have the least ef fect.

Investigation of the efficacy of two different laser types in the treatment of lower lip paresthesia after sagittal split ramus osteotomy

Orthognathic surgery involves invasive and major surgical procedures commonly used to correct maxillofacial deformities. Bilateral sagittal split ramus osteotomy (BSSO) is often used to treat dentofacial anomalies related to the mandible, but it can result in various complications, the most common of which is inferior alveolar nerve damage. Nerve damage–induced paresthesia of the lower lip significantly affects patient comfort. Medical treatments such as steroids and vitamin B, low-level laser therapy (LLLT), and platelet-rich fibrin (PRF) can be used as supportive therapies for nerve regeneration after damage. This study aimed to investigate the effectiveness of two different types of lasers in treating lower lip paresthesia after BSSO. This clinical trial was a controlled, single-center, prospective, single-blind, randomized study. Thirty patients were included in the study and randomly assigned to three groups: Group I (laser GRR, n = 10) received transcutaneous and transmucosal GRR laser treatment, Group II (Epic10 laser, n = 10) received transmucosal and transcutaneous Epic10 laser treatment, and Group III (vitamin B, n = 10) received B-complex vitamin tablets orally once a day. Two-point and brush tests were performed six times at specific intervals, and a visual analog scale was used to evaluate pain and sensitivity. Both vitamin B and laser therapies accelerated nerve regeneration. The contribution of the laser groups to the healing rate was better than that of the vitamin B group. Although there was no statistically significant difference between the two laser groups, clinical observations indicated better results in the GRR laser group.