Specific Test Research Articles

Basic instruments for measuring the quality of life in patients after stroke (literature review)

Improvements in drug therapy have led to an increase in the number of patients surviving after the acute period of the stroke. A significant proportion of stroke patients experience consequences such as impaired motor function, psychological and social disorders. This affects the quality of life (QoL) of patients. General and specialized tests are used to assess the QoL in patients after a stroke. The purpose of the study. Systematization of information about the main questionnaires used in assessing QoL in patients after the acute period of stroke. The search for relevant sources devoted to the topic of work was carried out in the bibliographic database Pubmed / Medline and the Google information system. The following keywords were used in the search queries: “quality of life”, “stroke”, “indicators” etc. Test names were also used as keywords. The characteristics of a number of general and specialized questionnaires that allow analyzing QoL in patients after a stroke are considered. Key practical information about the main questionnaires used abroad is summarized. Information on their applicability in domestic studies of QoL in patients who have suffered from a stroke is presented. The instruments that are most widely used in foreign practice are noted. The tests reviewed (general and specific) have usually acceptable psychometric properties (validity and reliability), although none are ideal or suitable for all situations. Continuing the development of comprehensive methods for assessing QoL in patients with stroke consequences at are best suited for everyday clinical practice remains one of the important tasks of medicine. Further development and widespread introduction of promising methods of QOL analysis into regular medical practice will increase the information content of assessments of the outcomes of therapy and rehabilitation.

When and What to Test for Diarrhea: Focus on Stool Testing.

To review stool diagnostic tests in acute and chronic diarrhea. Narrative review of published literature. (A). In acute diarrhea, stool tests are indicated when there is strong pre-test probability of infectious etiology or C. difficile infection (CDI) suggested by >3 unformed bowel movements per 24h, symptoms lasting >7 days, and circumstances that are suggestive of infection. Several commercially available rapid tests for bacterial, viral or protozoal infections may be offered in addition to traditional methods (e.g. culture, microscopy), and provide a result within 6 hours. For CDI infection, a highly sensitive test such as glutamate dehydrogenase test is required; however, this does not distinguish infection from carrier state. That differentiation requires specialized nucleic acid amplification test (for toxin B) or enzyme immunoassays for toxin A or B, which are unfortunately not generally offered by microbiology labs. (B). Chronic diarrhea may result from inflammatory, fatty, osmotic or secretory causes; the commonest causes are IBS-D/functional diarrhea. Current recommendations in societal guidelines or clinical practice updates regarding stool tests in IBS-D/functional diarrhea in the absence of alarm symptoms include testing for giardia, calprotectin, fecal immunochemical test (FIT), and bile acid diarrhea (BAD). Comprehensive stool biochemical analyses (osmolality, pH, electrolytes) differentiate osmotic from secretory diarrhea and identify laxative abuse. Specific stool diagnostic tests for BAD and exocrine pancreatic insufficiency can lead to specific diagnosis and treatments. Surrogate markers associated with high fecal output and rapid transit in chronic diarrhea are stool form and colonic transit. Fecal testing is still very relevant in the practice of gastroenterology and deserves introduction of advanced microbiological and biochemical tests.

A Statistical Method for EEG Channel Selection

A new statistical analysis of medical signals is proposed based on information extracted for diagnosis. Several specialized tests can be run on electroencephalography (EEG) signal due to its nonlinear behavior. Epileptic EEG signals are the main topic of this research. A statistics-based approach is proposed for the automatic selection of the relevant channels that will not only provide more accurate characterization but also require fewer computing resources. Moreover, the outcomes given by specific electrode pairs might indicate epileptic focus. By selecting the most efficient electrode placement, alarms for detecting inappropriate medical behavior could then be triggered.

Investigating the influence of bending stiffness and processing parameters on single-leg bending geometries of additively manufactured composites

In less than a decade, additive manufacturing technologies have been developed so successfully that they already produce small and medium-sized lot sizes of prototypes or customised components in the industry. With its new possibilities such as combining materials and technologies, the benefits of different technologies can be merged and broaden future application fields. One way is to print with one technology on a part produced by another. Thus, a thermally bonded part composed of, e.g., selectively sintered and material-extruded components can be created. This combination of technologies was considered in this study to investigate the bonding strength of extrusion-based layers on selectively sintered surfaces and the impact of nozzle temperature, orientation, and thickness of imprinted materials. The extrusion-based layers covered stiff (fibre-reinforced polyamide) and soft (thermoplastic polyurethane) material properties with pre-cracked single-leg bending (SLB) specimens to study their effect on delamination tendencies. This combination of materials and additive manufacturing technologies has not yet been studied for the SLB testing method. The scope of this study is to obtain more information on how relatively hard-hard and hard-soft combinations behave for this special testing method. The results of this testing method were evaluated using two different fracture mechanical approaches to determine the energy release rate. A clear trend towards an improved bonding, thus, higher values, was found for higher nozzle temperatures. Furthermore, a limitation regarding the required bending stiffness of the composites was found. Overall, the single-leg bending testing method enables a relative ranking for material combinations with a certain bending stiffness.

Changes in the diagnostic landscape of transthyretin amyloid cardiomyopathy (ATTR-CM): a comparison of tests ordered and test Intervals in 2020 Q4 and 2023 Q4

Abstract Background Transthyretin Amyloid Cardiomyopathy (ATTR-CM) is a genetic disease caused when misfolded transthyretin protein is deposited in the myocardium. Amyloidosis driven stiffness in heart muscles results in heart failure symptoms. ATTR-CM is underdiagnosed, requiring specialized tests to identify the condition. Purpose This paper examines and compares diagnostic tests and the time intervals between rounds of testing conducted to identify ATTR-CM in 2020 Q4 and 2023 Q4 in France (FR), Germany (DE), Italy (IT), Spain (ES) and the United Kingdom (UK). Methods A multi-centre online medical chart review was performed between November and December 2020, with 210 (FR: 46, DE: 40, IT: 43, ES: 42, UK: 39) cardiologists/internists providing data on 320 (FR: 71, DE: 63, IT: 64, ES: 63, UK: 59) patients diagnosed with ATTR-CM; and between October and November 2023, with 225 (FR: 45, DE: 48, IT: 48, ES: 45, UK: 39) cardiologists/Internists providing data on 780 (FR: 151, DE: 163, IT: 172, ES: 175, UK: 119) patients. Participants were screened for ATTR-CM patient management. We analysed the diagnostic tests ordered and tracked the intervals between batteries of tests to understand how the timing of diagnosis has changed across the EU4+UK. Results The average number of ATTR-CM diagnostic tests received by reported patients rose from 5.9 in 2020 to 7.4 in 2023, with ECHO with strain imaging (87%), Genetic tests (78%), Cardiac MRI (74%), Laboratory tests (67%), and Scintigraphy tests (65%) as the top 5 tests in Q4 2023. There was a notable increase in the use of ECHO with strain imaging, Laboratory tests, and Scintigraphy tests recorded in the Spanish patient cohort (p<0.01). Reported patients in Italy, Spain & UK received an increased average number of tests (p<0.05) [Table 1]. The recorded interval between the 1st and 2nd test batteries remained consistent between Q4 2020 and Q4 2023 (4.8-4.9 wks.), but the interval between the 2nd to 3rd rounds increased from 4.3 to 5.0 weeks. Timings between batteries increased in the France, Germany, Italy and UK data. Reported patients in Germany continue to experience the shortest intervals between batteries of tests (4.1 wks. between 1st and 2nd; 4.4 wks. between 2nd and 3rd batteries). Between Q4 2020 and Q4 2023, reported patients in Spain had an increase in the average number of tests received from 5.2 to 7.2, and were the only group with decreased time intervals (7.3 to 4.5 wks. between 1st and 2nd; 5.8 to 5.1 wks. between 2nd and 3rd batteries) Conclusion Results indicate that the use of certain diagnostic tests as well as the number of tests used to diagnose ATTR-CM has increased, however, intervals between testing batteries have also increased. This suggests that the increase in the number of tests used to diagnose ATTR-CM is possibly negating the necessity for more frequent testing. Further research in needed to confirm this and assess its impact on early detection of ATTR-CM.Table 1:Diagnostic Procedures by RegionTable 2:Testing battery intervals

A novel spine tester TO GO.

Often after large animal experiments in spinal research, the question arises-histology or biomechanics? While biomechanics are essential for informed decisions on the functionality of the therapy being studied, scientists often choose histological analysis alone. For biomechanical testing, for example, flexibility, specimens must be shipped to institutions with special testing equipment, as spine testers are complex and immobile. The specimens must usually be shipped frozen, and, thus, biological and histological investigations are not possible anymore. To allow both biomechanical and biological investigations with the same specimen and, thus, to reduce the number of required animals, the aim of the study was to develop a spine tester that can be shipped worldwide to test on-site. The "Spine Tester TO GO" was designed consisting of a frame with three motors that initiate pure moments and rotate the specimen in three motion planes. A load cell and an optical motion tracking system controlled the applied loads and measured range of motion (ROM) and neutral zone (NZ). As a proof of concept, the new machine was validated and compared under real experimental conditions with an existing testing machine already validated employing fresh bovine tail discs CY34 (n = 10). The new spine tester measured reasonable ROM and NZ from hysteresis curves, and the ROM of the two testing machines formed a high coefficient of determination R 2 = 0.986. However, higher ROM results of the new testing machine might be explained by the lower friction of the air bearings, which allowed more translational motion. The spine tester TO GO now opens up new opportunities for on-site flexibility tests and contributes hereby to the 3R principle by limiting the number of experimental animals needed to obtain full characterization of spine units at the macroscopic, biomechanical, biochemical, and histological level.

Experimental determination of damping coefficient of a support with elastic ring under harmonic loading

The article describes the possibility of determining the damping coefficient of a support with an elastic ring based on dry friction forces using a special test bench. The forced excitation force is set by the oscillations of a compact speaker installed on top of the oscillating mass through a U-shaped crossbar. The object of the study is a damper with an elastic ring, that is a thin-walled ring with evenly distributed bulges inside and outside, arranged in a checkerboard pattern. The damping coefficient is estimated using a device for simulating a rotor support, an acceleration sensor, an exciter speaker, a controller and a processing station. The amount of damping is estimated according to the width of the peak at the resonant frequency. A comparison is given of the magnitude of the damping coefficient obtained from the analysis of the resonance peak and from the decay rate during the impact experiment.

Prevalence of lateral epicondylitis among housewives in Lahore: a cross-sectional study

BackgroundLateral epicondylitis (LE) is characterized by pain, inflammation and local tenderness over the bony prominence of the lateral epicondyle and is exacerbated under stressful and repetitive movements such as prolonged supination and pronation movements, twisting (wringing, turning) and rolling activities (stirring and mixing). Lateral Epicondylitis ranks as the second most commonly diagnosed musculoskeletal condition. Females, especially housewives, are more affected by LE. It can lead to persistent elbow pain, reduced grip strength, limited arm movement, and difficulty performing daily tasks.ResultsAll of our 150 participants were women aged 25–50 + years. We found that 86% of housewives reported some level of pain (mild, moderate and severe) according to the PRTEE questionnaire but 39.33% (59/150) showed positive lateral epicondylitis cases assessed physically by special test (Cozen, Mills, Maudsley’s test). Among the individuals diagnosed with lateral epicondylitis, a significant majority, 71.19% (42 out of 59), reported pain in their right arm while only 16.95% were experiencing pain in their left arm, however, 11.86% (7 out of 59) reported pain in both arms. The odds ratio estimates of age groups suggested that the 25–30 years group had higher odds of getting LE about 0.95 than the reference group. Among the individuals with lateral epicondylitis, 59.32% (35 out of 59) were experiencing chronic pain, while 40.67% (24 out of 59) were dealing with acute pain. 54.24% (32/59) of individuals with lateral epicondylitis experienced functional disability in specific activities, while 28.81% (17/59) reported functional disability in routine activities.ConclusionWe found a high prevalence of 39.33% lateral epicondylitis among housewives. There is a dire need to raise awareness among housewives for changing their lifestyle and activities regimen in order to avoid any such disorders like L.E. Robust studies with larger sample sizes are needed to establish conclusive evidence.

Machine learning interpretability methods to characterize the importance of hematologic biomarkers in prognosticating patients with suspected infection

ObjectiveTo evaluate the effectiveness of Monocyte Distribution Width (MDW) in predicting sepsis outcomes in emergency department (ED) patients compared to other hematologic parameters and vital signs, and to determine whether routine parameters could substitute MDW in machine learning models. MethodsWe conducted a retrospective analysis of data from 10,229 ED patients admitted to a large regional safety-net hospital in Cleveland, Ohio who had suspected infections and developed sepsis-associated poor outcomes. We developed a new analytical framework consisting of seven data models and an ensemble of high accuracy machine learning (ML) algorithms (accuracy values ranging from 0.83 to 0.90) to predict sepsis-associated poor outcomes (3-day intensive care unit stay or death). Local Interpretable Model-Agnostic Explanation (LIME) and Shapley Additive Value (SHAP) interpretability methods were utilized to assess the contributions of individual hematologic parameters. ResultsThe ML interpretability analysis indicated that the predictive value of MDW is significantly reduced when other hematological parameters and vital signs are considered. The results suggest that complete blood count with differential (CBD-DIFF) alongside vital signs can effectively replace MDW in high accuracy machine learning algorithms for screening poor outcome associated with sepsis. ConclusionMDW, although a newly approved biomarker for sepsis, does not significantly enhance prediction models when combined with routinely available parameters and vital signs. Hospitals, especially those with resource constraints, can rely on existing parameters with high accuracy machine learning models to predict sepsis outcomes effectively, thereby reducing the need for specialized tests like MDW.

LABORATORY DIAGNOSIS OF VON WILLEBRAND DISEASE

The aim of the study. To determine the frequency of Willebrand disease (VWD) in patients which turned to the SI IBPTM of the NAMS of Ukraine with hemorrhagic manifestations. Research metods. Object and research methods. The object of the study were 298 people with hemorrhagic syndrome aged from 7 months to 66 years old who have turned to the specialists of the institution since 01.01.2021, of which 198 (66,4%) came in for the first time. Coagulation hemostasis was investigated by methods that meet international standards and recommendations. Ristocetin-cofactor activity of factor Willebrand (VWF: RCo), content of the antigen VWF (VWF: AG), and coagulant activity of factor VIII (FVIII: C) were performed for the diagnosis of VWD. Results and Conclusions. VWD were found in 29 patients (9,7%) of the 298 people with hemorrhagic syndrome. VWD was revealed in 7,6% of patients from the 198 patients who were first investigate. The 15 (51,7%) VWD patients was diagnosed for the first time. In 48 (24,2%) was first diagnosed with hereditary or caused by various factors of disaggregational thrombocytopathy. Von Willebrand disease is the most common type of congenital hemostasis disorders (0,6-1,3% of the population), the type of inheritance is autosomal recessive/dominant. An algorithmic approach should be applied to diagnosis. Laboratory diagnosis consists of screening coagulological tests and three levels special tests. To establish the diagnosis, the necessary tests are determined by VWF: RCo, VWF: Ag and FVIII: C.

Molecular diagnosis of E.coliO157:H7 Which Isolated from Children with Diarrhea by using Multiplex PCR

A total of 96 stool samples were collected from children with bloody diarrhea from two hospitals in Baghdad. All samples were surveyed and examined for the presence of the Escherichia coli O157:H7 and differentiate it from other Non -Sorbitol Fermenting Escherichia coli (NSF E. coli). The Bacterial isolates were identifed by using morphological diagnostic methods, Samples were cultured on liquid enrichment medium, incubated at 37C? for 24 hrs, and then cultured on Cefixime Tellurite -Sorbitol MacConkey Agar (CT- SMAC). 32 non-sorbitol fermenting bacterial isolates were obtained of which 11 were identified as Escherichia coli by using traditional biochemical tests and API20E diagnostic system without differentiation between serotype O157:H7 and other NSF E. coli isolates . Four special biochemical tests were done for serotype O157:H7 differentiation from other NSF bacteria. Only 3 isolates belonging to the serotype O157:H7 were obtained . Latex agglutination test for O157 and H7 showed that the 3 isolates gave positive results with both tests. The Bacterial isolates were identifed by using Multiplex Polymerase Chain Reaction (MPCR) technology for the presence or absence of 4 genes (Stx1, Stx2, hlyA and eaeA) that encode for main virulence factors to diagnose E. coli O157:H7 isolated By using specific primers in MPCR . The result showed that one E. coli O157:H7 isolates contain all 4 genes , other isolates contain 3 genes: Stx2, hlyA & eaeA.

Current regulatory requirements for stability studies of biological medicinal products: a review

INTRODUCTION. The stability assessment of biological medicinal products (BMPs) requires special approaches and regulatory requirements. Therefore, BMPs require relevant national guidelines, which are an important prerequisite for the assurance of the safe and effective use of BMPs.AIM. This study aimed to analyse national and international requirements for the stability assessment of BMPs in order to use the results to inform future development of a unified regulatory approach to estimating and confirming shelf-life periods for BMPs.DISCUSSION. Most biotechnological medicinal products (BTMPs) are proteins and are highly sensitive to environmental factors by nature. Therefore, the shelf life of a BTMP is established on the basis of real-time stability studies. Stability testing under accelerated and stress conditions is conducted to support shelf-life claims and to characterise the mechanism of protein structure degradation. The results of accelerated and stress studies can be used to select the most sensitive stability-indicating parameters and testing methods. National and international regulatory authorities have developed specialised guidelines for stability studies of BMPs of various origins, and the stability assessment approaches in the regulatory system of the Eurasian Economic Union (EAEU) are harmonised with international standards. Special considerations associated with the stability of vaccines imply that stability studies of vaccines should not only establish shelf life but also investigate stability after reconstitution and after short-term temperature excursions from the recommended cold-chain conditions.CONCLUSIONS. Special stability testing considerations for various groups of BMPs (including BTMPs and immunobiologicals) indicate the need to develop and improve the system of requirements for BMP stability assessment. This will facilitate the optimisation of the life cycle of BMPs in the Russian Federation and the other EAEU member states.

Comparison of standard Bayesian methods and PINNs for the reconstruction of acoustic fields in 'in situ' combustion chambers

Acoustic measurements, utilizing sensors such as microphones strategically placed, are commonly employed to monitor acoustic systems and extract quantities of interest, such as acoustic reflection coefficients. Typically, a specialized test rig must be constructed to allow for external harmonic acoustic forcing via loudspeakers. In this study, we propose two different methods: physics-informed neural networks (PINNs) and the extended Kalman filter, to reconstruct the acoustic field of a system and assess the acoustic reflection coefficient at a defined boundary. We demonstrate numerically that a single external broadband forcing signal suffices for these methods. This implies that these methods can be applied to 'in situ' configurations, such as industrial combustion chambers, where the broadband nature of combustion noise serves as the acoustic forcing element. Furthermore, we investigate the performance of the two aforementioned methods in reconstructing the acoustic systems and corresponding acoustic boundaries.

A-283 Serologic and molecular testing for the diagnosis of Rickettsia, Ehrlicha, and Anaplasma infections in patients in Maryland

Abstract Background Rickettsia, Anaplasma, and Ehrlichia are underrecognized tick-borne pathogens of increasing human importance. As tick habitats are expanding and populations are increasing, human exposure to these pathogens is also increased in recent years. Unfortunately, while treatment is usually simple, diagnosis can be difficult as it requires specialized testing for clinical diagnosis - generally performed only at reference laboratories. Methods To better understand the prevalence, diagnosis, and testing patterns for Rickettisal infections, Anaplasmosis, and Ehrlichiosis in Maryland, a retrospective analysis of all serologic and molecular testing for Rickettsia, Anaplasma, and Ehrlichia species performed for the University of Maryland Medical System from 2018-2022 was conducted. Eight hospitals within the University of Maryland Medical System (Central Maryland and Maryland’s Eastern Shore) diagnose Rickettsia, Anaplasma, and Ehrlichia infections using serologic and molecular testing. Results Between 2018-2022, an average of 413 individuals were tested for Rickettsia, Anaplasma, and Ehrlichia each year. On average 315 serologic tests for Rocky Mountain Spotted Fever (RMSF) group Rickettsia, 195 serologic tests for Ehrlichia chaffeensis (Anaplasma serology is not available), and 165 molecular tests for the detection of Anaplasma and Ehrlichia species were ordered each year. Clinical indications for testing included tick bite, fever, chills, severe headaches, muscle aches, and rash. Overall, 17% of individuals tested were positive for IgG antibodies to RMSF group Rickettsia, however only 1% were positive for IgM antibodies. Further, 20% of individuals tested were positive for IgG antibodies to Ehrlichia chaffeensis, while <1% were positive for IgM. Acute and convalescent samples were not tested for any individuals. Molecular evidence of infection was found in 8% of individuals tested. Nineteen precent were positive for Anaplasma phagocytophilum and the remaining 81% were positive for Ehrlichia chaffeensis. Interestingly, only two individuals had positive results from both molecular and serologic testing. Conclusions Results from serologic and molecular testing show that Rickettsia, Anaplasma, and Ehrlichia are important human pathogens with the potential to cause significant morbidity. However, lack of follow-up serology, and laboratory tests that confirm acute infection make definitive diagnosis difficult. Increased awareness of Rickettsial diseases and appropriate diagnostics is needed.

Assessing subscapularis tears: Relationship between special tests and pain & tear severity

BackgroundThe objective of this study is to examine the association between special tests for subscapularis tears and both pain and tear severity. MethodsNine hundred and two patients (145 with isolated lesions and 757 with combined lesions) diagnosed with arthroscopically confirmed subscapularis tears between 2010 and 2022. Subscapularis tear severity was classified according to Lafosse classification type I, II, III and IV. Preoperative Visual Analogue Scale (VAS) pain score at rest of the patients, flexion and abduction range of motion (ROM) of the shoulder and the results of the Lift-off test (LOT), Belly Press test (BPT), Bear Hug test (BHT), and Empty Can test (ECT) were documented. ResultsThe sensitivity of LOT in isolated and combined tears was 70.3 % and 69.5 %, 45.6 % and 41.2 % of BPT, 72.1 % and 72.6 % of BHT, 81.2 % and 84.1 % of ECT, respectively. There was no association between the severity of the subscapularis tear and the sensitivity in all special tests (p > 0.05). Only the ECT was observed to be associated with pain in the multivariate logistic regression analysis (OR = 33.1, p < 0.001). ConclusionsThe special tests used to evaluate subscapularis tears are neither sensitive to the severity of the tear nor to pain except for ECT. BHT is the most successful test to detect any subscapularis tear in both isolated and combined tears. Pain severity was related to the presence of a rotator cuff lesion accompanying subscapularis lesion, but not with the severity of subscapularis or remaining rotator cuff tear. Study designLevels of Evidence III, cross-sectional archive study. Clinical trial registration numberSince the study was a retrospective archive study, there was no clinical trial registration.

Design and realization of multifunctional energy meter calibration station under extreme conditions

Abstract This paper designs a multifunctional calibration station that can be installed inside the temperature box in order to adapt to some of the special test requirements, which can be used for the testing of most types of energy meters on the market. Extreme environments such as high and low temperatures can easily cause cracks in equipment welds, aging of material insulation, and functionally cause sensitive components to drift affecting the accuracy of testing during the life cycle of the calibrator. This multifunctional calibration station designed and implemented in this paper is capable of maintaining its functionality without being destroyed under repeated experiences of extreme conditions. In this paper, a multifunctional calibration station is designed and realised. In order to verify the influence of the calibrator on the calibration error of the energy meter after repeatedly experiencing extreme conditions, a comparison test of 40 cycles was carried out by comparing the calibrator with the one placed at room temperature, and the difference between the two calibrators’ measurement results did not show a regular growth trend with the increase in the number of measurement cycles, which proves that the calibrator is able to keep its function undamaged under the repeated experience of extreme conditions.

Physiotherapy practices in the clinical assessment of lateral elbow tendinopathy: An international survey.

Understanding physiotherapy practices is important to identify variations from empirical evidence and highlight requirements for training. This survey explored international physiotherapy practices for assessment of lateral elbow tendinopathy (LET). Two hundred ninety-nine surveyed physiotherapists from eight member countries of the International Federation of Manual and Orthopaedic Physical Therapists completed the survey. Respondents rated their frequency of use (never, rarely, sometimes, often, and always) for items related to: patient history; diagnostic tests; grip and upper limb strength; cervical and neurological assessment; and medical imaging. To establish practices, the five response categories were dichotomised into routine practice (often, always) and not-routine practice (sometimes, rarely, never). A response rate of ≥70% for each dichotomy was used to determine whether an assessment item was deemed routine practice or not, with items not meeting either criterion considered neither routine nor not-routine practice. Most respondents were from United States (63%). The 'chair pick up test', 'cervical special tests', and 'plain radiograph' met our criteria for not routine practice (i.e., 70%, 72%, and 71%, respectively). All other assessment items did not meet the criteria to be considered routine or not-routine practice. The chair pick-up test, cervical spine special tests (e.g., Spurling's test), and plain radiography appear to not be routinely used in the assessment of LET. The finding that no assessment technique met the criteria for routine use may imply that physiotherapists adopt a nuanced approach to selecting clinical assessment items as opposed to routinely applying tests.

ОБ ИНДИКАТОРАХ ФИЗИЧЕСКОЙ КУЛЬТУРЫ ШКОЛЬНИКОВ И СТУДЕНТОВ (обзор)

The article analyzes the effectiveness of indicators of physical education programs for schoolchildren and students. It has been established that in order to evaluate the effectiveness of the educational process, it is necessary to develop standards for assessing changes in the indicators of general physical preparedness of students from the beginning to the end of the school year. The evaluation of schoolchildren mastering the physical education program exercises requires justification for the use of special tests and standards for assessing sports movements, as well as control exercises when performing certain sections of the program.

Relationship between the healing rate of post-extraction sites and the quantity of platelets present in the blood: a retrospective observational study.

In daily surgical practice, the dentist deals with various types of oral surgery. At the first visit, the patient fills out a questionnaire about their state of health. If the questionnaire does not reveal any particular hematological problems, no special tests are usually required to determine the platelet count. The aim of this prospective study was to evaluate the healing process of patients and its correlation with platelet levels before surgery. A total of 50 patients were included in whom blood chemistry tests were performed with special attention to the platelet count and before their mandibular eights were extracted .The type of healing (EHI) and pain on the second day (VAS) were assessed using methods validated in the literature. After the EHI and VAS scores were noted in the medical records, envelopes containing the platelet scores of the previously requested blood samples, which were not read at the time of observation, were opened. An increase in EHI scores and a decrease in VAS scores was observed that were statistically significantly correlated with increasing platelet scores. These results suggest that the dentist should request chemistry tests on preoperative blood, especially if the patient is to undergo a particularly demanding oral surgical procedure, such as implants, guided bone regeneration or complex extractions.

Optical communication in a turbulent atmosphere via the orbital angular momentum of a laser beam. II. Symbol error rate in a data line

A numerical simulation is applied to study the symbol error rate (SER) in an optical communication system with data modulation by the orbital angular momentum (OAM) of an optical beam propagating through a turbulent atmosphere. In this case, the OAM is calculated from pre-recorded powers of azimuthal modes, while the complex modes are the coefficients of expansion of the wave field of the beam into spiral harmonics. The SER is calculated as a function of turbulence conditions for the LG1 and LG4 beams and data line lengths, as well as the number of receiving channels (number of recorded powers of azimuthal modes) and size of the input aperture of the receiving telescope. It is shown that the range of angular harmonics can be optimized to diminish the SER. It is found that knowing the probability density of OAM fluctuations, with a pre-determined average OAM and its variance, we can estimate the SER without conducting special numerical tests.