Specific Rate Research Articles

Shoulder Injury Incidence and Epidemiology in Youth, High School, and Collegiate Fastpitch Softball Players: A Systematic Review and Future Research Perspectives.

Fastpitch softball is one of the most popular sports in the United States among young female athletes. Softball players regularly subject their shoulders to extreme range of motion and high velocity movements. To date, no systematic review has reported on the epidemiology and incidence of shoulder injuries in softball players. To describe the incidence and epidemiology of softball-related shoulder injuries in youth, high school, and collegiate female softball players. PubMed, Web of Science, and Embase were searched for relevant English language articles from 1980 to 2023. Studies selected based on predefined inclusion criteria. Studies were required to be available full text, in English. Systematic review. Level 4. A preliminary screening was performed based on study title and abstract. In the subsequent screening, the full text versions of the remaining articles were evaluated by 2 reviewers for the fulfillment of the inclusion criteria. A total of 7 articles met criteria for inclusion. All studies evaluated injuries among softball players for at least 1 season. In total, there were 1107 softball-related shoulder injuries reported in the 7 studies included in this systematic review. Of the 3 studies that included a shoulder injury rate, a mean rate of 4.01 shoulder injuries per 10,000 athlete-exposures was calculated. The 2 most common shoulder injuries were shoulder muscle-tendon strains (297) and shoulder/biceps tendinitis (220). High-level prospective studies reporting injury incidence and risk factors among female softball players are extremely limited. Only 2 studies eligible for inclusion in this systematic review were prospective in nature, with neither of these reporting the specific injury rate for shoulder injuries among softball players.

A comprehensive study on dry sliding wear and in-vitro degradation of AZ31 composite with 6 wt% Sn and 1.5 wt% TiO2 fabricated by stir casting

Abstract This experimental study investigates the dry sliding wear behaviour of novel AZ31 composite with 6 wt% Sn and 1.5 wt% TiO2 samples, focusing on the influence of sliding distance and normal load. Additionally, the research examines degradation rates during a 120-hour immersion period in simulated body fluid (SBF). The wear volume loss increased significantly with higher loads and longer sliding distances, showing a 142% rise from 1000 m to 2000 m and 76% from 2000 m to 3000 m under a 5 N load, peaking at a 25 N load over 5000 m. The specific wear rate dropped by 39% from 5 N to 15 N but increased with distance due to thermal softening, while the coefficient of friction decreased from 0.284 at 1000 m to 0.213 at 5000 m under 5 N. FESEM analysis revealed a transition from abrasive to delamination wear, with a protective oxide layer forming during sliding. Sn in the composite formed hard Mg2Sn intermetallic compounds, affecting crack formation and propagation under higher loads. Wear debris analysis showed both abrasive and delamination wear mechanisms, highlighting the protective role of the oxide layer. The degradation rate increased rapidly during the initial immersion stage in simulated body fluid (SBF), reaching 15.9 mm year−1 after 24 h, and then stabilizing after 48 h. Hydrogen evolution rose sharply from 0.28 ml cm−12 at 2 h to 7.6 ml cm−12 within 24 h, with a 92% increase by 48 h and an additional 38% increase from 48 to 72 h. Post-immersion FESEM analysis showed corroded surfaces with protective layers, cracks, and pitting corrosion. Magnesium hydroxide (Mg(OH)2) and hydroxyapatite played crucial roles in inhibiting corrosion. This analysis provides insights into the wear, and degradation dynamics of the AZ31-6Sn/1.5TiO2 composite, with implications for engineering applications and the development of biodegradable implants in biomedical fields.

Phonocardiogram Signal Analysis Based Premature Cardiac Influence Detection using Resnet50 CNN for Public Health Protection

Phonocardiogram (PCG) signal analysis plays a crucial role in the early detection of cardiac abnormalities, which is essential for public health protection. The premature disease prediction is tedious because the feature analysis takes place dimensionality problems which leads poor accuracy. The prevailing ensemble learning models’ methods doesn’t concentrate disease margin facts and properties during classification produce higher false rate because for adjusting feature margins gets lower accuracy. To resolve this problem, we propose a efficient Fuzzy c-means feature modality based Resnet50-RNN to detect premature cardiac influence detection for improving public health. The research proposes a method for premature cardiac influence detection using a ResNet50 Convolutional Neural Network (CNN) model for early prediction of heart disease. To address the issue of imbalanced data, Synthetic Minority Oversampling Technique (SMOTE) is employed for preprocessing. The Cardiac Disease Influence Rate (CDIR) is then used to identify the maximum deficiency-affected feature margins. Fuzzy c-means is utilized to select the mutual features associated with the heart disease influence rate. The ResNet50 CNN model is employed for classification, enabling the prediction of disease margins by risk category. The proposed system effectively identifies the disease based on the disease-affected scaling margin, leading to early disease impact prediction with higher accuracy, specificity, F1-measure, and lower false rates compared to other existing systems. The implementation also demonstrates reduced time complexity.

Superlubricity of multilayer titanium doped DLC coatings by using low SAPS organic additives in base oil

This study systematically investigates the tribological performance of titanium doped diamond-like carbon monolayer and multilayer coatings with superior mechanical properties. The coatings were lubricated in poly alpha olefin grade 4 (PAO4) base oil, containing three concentrations of two organic, ashless, and sulfur free (low SAPS) antiwear, and extreme pressure additives with different amounts of phosphorus and nitrogen (Duraphos® 178 and Duraphos® OAP). The multilayer Ti-doped DLC coatings exhibited superior tribological performance compared to uncoated steel, undoped DLC, and monolayer Ti-DLC coatings. They exhibited coefficient of friction values which were in the range of 0.013 and 0.006 (superlubricity) for formulations with Duraphos® OAP. Duraphos® 178 significantly lowered the specific wear rates of both the monolayer and multilayer coatings.

An optimized and intelligent metaverse intrusion detection system based on rough sets

The convergence of the Internet of Things (IoT) and the Metaverse is revolutionizing the digital world by providing immersive, interactive environments as well as new data transmission opportunities. However, this rapid integration raises complex security issues, including an increased risk of unlawful access and data breaches. Strong cybersecurity measures are required to identify and prevent these attacks, preserving the security and confidentiality of users. Finding significant features for recognizing malicious attacks and enhancing the accuracy of network intrusion detection in general, and particularly in the virtual environment, are some of the significant research needs. This paper introduces an intelligent intrusion detection system (IIDS) based on rough set-based electric eel foraging optimization (RSEEFO) in conjunction with the AdaBoost-based classification algorithm. The main objective of this system is to detect and recognize different types of attacks on the interaction and connectivity between the IoT and the metaverse. The proposed IIDS-RSEEFO consists of three phases, which are data pre-processing, multi-IoT attack classification, and evaluation. The main problems associated with the adopted dataset are handled in data pre-processing. Then, in the second phase, a one-versus-all approach is employed along with RSEEFO and AdaBoost to handle the multi-class classification problem. Finally, several evaluation metrics are employed to assess the reliability and robustness of the proposed IIDS-RSEEFO. The proposed IIDS was tested on CIC-IoT-2023 and validated on UNSWNB-15. It achieved high accuracy across all attack types of CIC-IoT-2023, with accuracies of 99.7 %, 100 %, 100 %, 99.8 %, 100 %, 100 %, 99.8 %, and 100 % for benign traffic, DDoS, brute force, spoofing, DoS, Mirai, recon, and web-Based respectively, accompanied by robust sensitivity, F1-Score, Specificity, G-Mean, and crossover-error rate metrics demonstrating its effectiveness in accurately predicting each attack type. Additionally, it obtained high accuracy for all attack types of UNSWNB-15, with accuracies of 96.48 %, 99.12 %, 99.24 %, 93.78 %, 92.55 %, 92.55 %, 92.55 %, 94.73 %, 94.73 %, 98.09 %, 98.39 %, 99.50 %, and 99.95 % for analysis, backdoor, DoS, exploits, fuzzers, generic, normal, reconnaissance, shellcode, and worms, respectively. In addition, the results evaluated that the proposed model is superior compared to the existing intrusion detection systems.

Impact of N loading on Microbial Community Structure and Nitrogen Removal of an Activated Sludge Process with Long SRT for municipal wastewater treatment

Biological nutrient removal process is pivotal in controlling nitrogen and phosphorus from municipal wastewater treatment and reclamation plants in the water environment. The efficiency of municipal wastewater treatment is affected by the fluctuation of influent quality. In this study, the impact of N loading on the removal efficiency and the microbial community structure of activated sludge with long sludge retention time were investigated. The results showed that the effluent NH4+-N and NO2--N concentration were lower than 0.5 mg/L, and the TN removal efficiencies were 79.77% and 65.80%, respectively. The dehydrogenase activity, specific oxygen uptake rate, specific nitrification rate, and specific denitrification rate increased as the N loading increasing. At the phylum level, the most dominant bacterial was affiliated with Proteobacteria in the two systems, accounting for 60.65% and 48.62%, respectively. At the genus level, Acinetobacter, Thauera, and Zoogloea played significant roles in denitrification. The ammonia oxidation bacteria and nitrite-oxidizing bacteria were of the genus Nitrosomonas (r-strategist) and Nitrospira (K-strategist).

Tribology of Ti2/Cr2 and (TiCr)2AlCx MAX Phase Ceramics

The MAX phase ceramics namely Ti2AlCx, Cr2AlCx, and (TiCr)2AlCx were examined under dry sliding conditions against stainless steel ball at room temperature and 5 N applied normal load using a Ball-on-disk tribometer. At 5 N, 100 m sliding distance and 20 cm/s sliding velocity, Cr2AlCx, and (TiCr)2AlCx ceramic samples exhibited low specific wear rate (3.2 × 10-7 cm3/Nm and 4.2 × 10-7 cm3/Nm), while the coefficients of friction were 0.31 and 0.10, respectively. At 5 N, 100 m and increasing velocity from 5 cm/s to 20 cm/s, Ti2AlCx sample the coefficients of friction decreases from 0.25 to 0.14. The specific wear rate of Ti2AlCx sample was 6.7 × 10-7 cm3/N m at 5 N, 100 m and 5 m/s, and decreases with increasing velocity (3.3 × 10-7 cm3/N m at 20 m/s). The correlations between observed tribological properties and tribo-film characteristics were discussed.

Item-validity analysis of the SED-S in a multicentre study of adults with intellectual disabilities.

Valid and reliable instruments for measuring emotional development are critical for a proper diagnostic assignment in individuals with intellectual disabilities. This exploratory study examined the psychometric properties of the items on the Scale of Emotional Development-Short (SED-S). The sample included 612 adults with intellectual disabilities (Mage = 37.35, SDage = 13.27; 59.8% males). Item validity analysis comprising sensitivity and specificity rates and discriminatory power were determined. The relative mean frequency of 'yes' answers to all 200 items was 29.5%. The mean sensitivity rate was 67.5% and the mean specificity rate was 79.3%. Most items (85.0%) showed good discriminatory power with the adjacent stage(s), especially between SED-1, SED-2, SED-3 and SED-4. Particularly in SED-4 some items showed weaknesses in the differentiation between these stages. This study adds to previous validation studies by showing that most SED-S items have psychometrically sound properties.

Rule-based natural language processing to examine variation in worsening heart failure hospitalizations by age, sex, race and ethnicity, and left ventricular ejection fraction

BackgroundPrior studies characterizing worsening heart failure events (WHFE) have been limited in using structured healthcare data from hospitalizations, and with little exploration of sociodemographic variation. The current study examined the impact of incorporating unstructured data to identify WHFE, describing age-, sex-, race and ethnicity-, and left ventricular ejection fraction (LVEF)-specific rates. MethodsAdult members of Kaiser Permanente Southern California (KPSC) with a HF diagnosis between 2014-2018 were followed through 2019 to identify hospitalized WHFE. The main outcome was hospitalizations with a principal or secondary HF discharge diagnosis meeting rule-based Natural Language Processing (NLP) criteria for WHFE. In comparison, we examined hospitalizations with a principal discharge diagnosis of HF. Age-, sex-, and race and ethnicity-adjusted rates per 100 person-years (PY) were calculated among age, sex, race and ethnicity (non-Hispanic (NH) Asian/Pacific Islander [API], Hispanic, NH Black, NH White) and LVEF subgroups. ResultsAmong 44,863 adults with HF, 10,560 (23.5%) had an NLP-defined, hospitalized WHFE. Adjusted rates (per 100 PY) of WHFE using NLP were higher compared to rates based only on HF principal discharge diagnosis codes (12.7 and 9.3, respectively), and this followed similar patterns among subgroups, with the highest rates among adults ≥75 years (16.3 and 11.2), men (13.2 and 9.7), and NH Black (16.9 and 14.3) and Hispanic adults (15.3 and 11.4), and adults with reduced LVEF (16.2 and 14.0). Using NLP disproportionately increased the perceived burden of WHFE among API and adults with mid-range and preserved LVEF. ConclusionRule-based NLP improved the capture of hospitalized WHFE above principal discharge diagnosis codes alone. Applying standardized consensus definitions to EHR data may improve understanding of the burden of WHFE and promote optimal care overall and in specific sociodemographic groups.

Birds of a Feather: Resolving Stellar Mass Assembly with JWST/NIRCam in a Pair of Kindred z ∼ 2 Dusty Star-forming Galaxies Lensed by the PLCK G165.7+67.0 Cluster

We present a new parametric lens model for the G165.7+67.0 galaxy cluster, which was discovered with Planck through its bright submillimeter flux, originating from a pair of extraordinary dusty star-forming galaxies (DSFGs) at z ≈ 2.2. Using JWST and interferometric mm/radio observations, we characterize the intrinsic physical properties of the DSFGs, which are separated by only ∼1″ (8 kpc) and a velocity difference ΔV ≲ 600 km s−1 in the source plane, and thus are likely undergoing a major merger. Boasting intrinsic star formation rates SFRIR = 320 ± 70 and 400 ± 80 M ⊙ yr−1, stellar masses of log[M⋆/M⊙]=10.2±0.1 and 10.3 ± 0.1, and dust attenuations of A V = 1.5 ± 0.3 and 1.2 ± 0.3, they are remarkably similar objects. We perform spatially resolved pixel-by-pixel spectral energy distribution (SED) fitting using rest-frame near-UV to near-IR imaging from JWST/NIRCam for both galaxies, resolving some stellar structures down to 100 pc scales. Based on their resolved specific star formation rates (SFRs) and UVJ colors, both DSFGs are experiencing significant galaxy-scale star formation events. If they are indeed interacting gravitationally, this strong starburst could be the hallmark of gas that has been disrupted by an initial close passage. In contrast, the host galaxy of SN H0pe has a much lower SFR than the DSFGs, and we present evidence for the onset of inside-out quenching and large column densities of dust even in regions of low specific SFR. Based on the intrinsic SFRs of the DSFGs inferred from UV through far-infrared SED modeling, this pair of objects alone is predicted to yield an observable 1.1 ± 0.2 core-collapse supernovae per year, making this cluster field ripe for continued monitoring.

Reframing Confidence Instructions to Child Eyewitness Reduces Overconfidence but Does Not Improve Confidence–Accuracy Calibration

ABSTRACTChildren are well‐documented to exhibit poor confidence–accuracy calibration on lineup identification tasks. Children tend to report overconfidence in their (often inaccurate) lineup identification decisions. This research explored the extent to which school‐aged children's (N = 142; 6‐ to 8‐year‐old) confidence reports are implicitly driven by perceived social pressure to provide a specific confidence rating. Children were randomly assigned to two different confidence instruction conditions: the neutral (n = 69) or the reframed conditions (n = 73). The reframed instructions encouraged honesty and instructed children to ignore perceived pressure when reporting confidence. Results revealed that the reframed instructions resulted in more conservative confidence judgments; however, this shift did not translate into those confidence ratings better reflecting children's identification accuracy. Overall, these findings provide evidence that, while external or social factors play a contributing role, other aspects of development are likely contributing more to the poor confidence–accuracy calibration observed with child eyewitnesses.

The H i Reservoir in Central Spiral Galaxies and the Implied Star Formation Process ∗ ∗ This is the fourth paper in the “From Halos to Galaxies” series.

The cold interstellar medium (ISM) as the raw material for star formation is critical to understanding galaxy evolution. It is generally understood that galaxies stop making stars when, in one way or another, they run out of gas. However, here we provide evidence that central spiral galaxies remain rich in atomic gas even if their star formation rate (SFR) and molecular gas fraction have dropped significantly compared to “normal” star-forming galaxies of the same mass. Since H i is sensitive to external processes, here we investigate central spiral galaxies using a combined sample from the Sloan Digital Sky Survey, Arecibo Legacy Fast ALFA survey, and the extended GALEX Arecibo SDSS Survey. After proper incompleteness corrections, we find that the key H i scaling relations for central spirals show significant but regular systematic dependence on stellar mass. At any given stellar mass, the H i gas mass fraction is about constant with changing specific star formation rate (sSFR), which suggests that H i reservoir is ubiquitous in central spirals with any star formation status down to M * ∼ 109 M ⊙. Together with the tight correlation between the molecular gas mass fraction and sSFR for galaxies across a wide range of different properties, it suggests that the decline of SFR of all central spirals in the local Universe is due to the halt of H2 supply, though there is plenty of H i gas around. These hence provide critical observations of the dramatically different behavior of the cold multiphase ISM, and a key to understand the star formation process and quenching mechanism.

Ocular adnexal lymphoma - a retrospective study and review of the literature.

To review the characteristics of all Slovenian patients with ocular adnexal lymphoma (OAL) in the period of 24 years with the aim of evaluating demographic data, lymphoma location and type, disease stage, treatment modality, local control rate and survival rate. All patients with histologically diagnosed OAL in the main tertiary centre of Slovenia, Eye Hospital, University Medical Centre Ljubljana, who were treated at Institute of Oncology Ljubljana were included in the study. Patients' data were collected from October 1995 through April 2019. Seventy-four patients were included in the study having a median age of 68 years at diagnosis. The majority of lymphomas were of B-cell origin (98.6%). The most frequent type was the extranodal marginal zone B-cell lymphoma (MALT) (71.6%). Orbital lymphomas were diagnosed in 56 cases (75.7%) and conjunctival in 18 cases (24.3%). Ocular manifestation was the first sign of the disease in 78.4% of patients and in 67.6% of patients ocular adnexa were the only disease location. Fifty-one patients (68.9%) were treated with radiotherapy, 7 patients (9.4%) with systemic treatment, 5 patients (6.8%) with combined radiotherapy and systemic treatment and in 11 patients, biopsy and active surveillance strategy was applied (14.9%). Local control of the disease was achieved in 96.6% of treated patients. Median overall survival of the whole study group has not been reached yet. Five-year overall survival rate was 80.1% (95% CI 68.1% - 88.5%) and 5-year lymphoma specific survival rate was 87.2% (95% CI 83.2%-91.2%). OALs comprise a group of heterogeneous diseases with variable outcomes depending predominately on the patient's age and lymphoma type, with low grade lymphomas carrying good prognosis even in elderly patients.

SiO2 decorated wood nanocomposite with enhanced mechanical performance, flame and water resistance

Development of lightweight and strong structural material using fast-growing poplar wood is promising for green and sustainable engineering. Herein, the overall performances of fast-growing natural poplar wood (NPW) are significantly enhanced via delignification, in situ growth of SiO2 followed by densification. The SiO2/compressed-delignified-wood (SiO2/CDW) nanocomposite obtained exhibits outstanding mechanical properties including a bending strength of 395.6 ​MPa, a tensile strength of 253.4 ​MPa, and a toughness of 7.1 ​MJ/m3, which is improved by 1548 ​%, 240 ​% and 590 ​%, respectively compared with NPW. In addition, the ignition time and burning time of SiO2/CDW nanocomposite are prolonged by 700 ​% and 112 ​% compared to those of NPW. Moreover, the specific wear rate of SiO2/CDW is 18 ​× ​10−6 mm3/Nm, which is 72.6 ​% lower than that of NPW. Moreover, the spring-back ratios of SiO2/CDW in 95 ​% and in water are 45.2 ​% and 66.7 ​%, which are lower than those of CDW (64.6 ​% and 92.4 ​%). The SiO2/CDW nanocomposite with enhanced mechanical, flame/water retardant and wear performances are promising to meet the needs of modern engineering as green and sustainable materials.

Computational investigation of both geometric and fluidic compressible turbulent thrust vectoring, using a Coanda based nozzle

This study addresses the challenge of enhancing aircraft maneuverability, particularly for vertical landing and takeoff, focusing on the fluidic aerial Coanda high efficiency orienting jet nozzle that employs the Coanda effect to achieve thrust vectoring. This research advances understanding of the interplay between geometric and fluidic factors in thrust vectoring. Stationary, turbulent, and compressible flow conditions are assumed, employing Favre-averaged Reynolds-averaged Navier–Stokes approach with the standard k-ε model. Computational solutions were obtained using a pressure-based finite volume method and a structured computational grid. The key findings include thrust vectoring enhancement due to an increase in the total mass flow rate, septum position (at no shock wave-related issues), and Reynolds number. In addition, shock wave formation (at specific mass flow rates and septum positions) considerably affects thrust vectoring. These insights are crucial for optimizing Coanda-based nozzle design in advanced propulsion systems, including in unmanned aircraft vehicles.

Lidocaine pre-treatment for Succinylcholine induced postoperative myalgia and associated factors: Longitudinal study

IntroductionPostoperative myalgia in surgical patients is mainly caused by the routinely administered depolarizing muscle relaxant, Succinylcholine. There are many proposed strategies but no one were indicated as ideal preventive mechanisms for Succinylcholine induced post-operative myalgia. Even if data were sparse, Lidocaine pretreatment can reduce postoperative myalgia which requires further supportive evidences urging the initiation of this study. MethodsProspective longitudinal cohort study was conducted from March to May 2021 at Dessie Comprehensive Specialized Hospital on 208 adult surgical patients. Patients pretreated with Lidocaine preoperatively were grouped as exposed and others as unexposed. Patients meeting the inclusion criteria during the study period were selected sequentially from the daily operation schedule list. Postoperative myalgia level was measured using post-operative myalgia survey repeatedly. The result was analyzed by Cochran's Q test and generalized estimating equation (GEE). Adjusted odds ratio with 95 % confidence interval and p value < 0.05 was used to show the difference, direction and strength of association. ResultExposure specific incidence rate showed that 22 %, 22 % and 29.8 % of patients exposed to Lidocaine and 40.6 %, 42.7 % and 34 % not exposed to Lidocaine developed myalgia at 12, 24, and 48 h respectively. There is no significant difference in the incidence of myalgia over time between the repeated measurements in Lidocaine exposed patients (p = 0.513) but in non-exposed patients (p = 0.003). Also, there is no difference in the distribution of other predictors between Lidocaine exposed and non-exposed groups (p > 0.05). Exposure to Lidocaine reduces postoperative myalgia significantly [AOR = 0.33, 95 % CI = (0.17,0.66)]. Multimodal analgesia [AOR = 0.32, 95 % CI = (0.18,0.55)], non-steroidal anti-inflammatory drugs alone [AOR = 0.47, 95 % CI = (0.29,0.76)], postoperative immobility [AOR = 0.61, 95 % CI = (0.47,0.8)], and being male [AOR = 0.48, 95 % CI = (0.26,0.87)] were other determinants in reducing Succinylcholine induced postoperative myalgia. ConclusionLidocaine pretreatment can significantly reduce the occurrence of Succinylcholine induced postoperative myalgia. Additionally, usage of multimodal analgesia with non-steroidal anti-inflammatory drugs or even only non-steroidal anti-inflammatory drugs in the intraoperative and postoperative period can reduce Succinylcholine induced postoperative myalgia.

Reliability and relevance of the ES®-RHE model for in vitro skin irritation test application

IntroductionIn vitro methods have been widely used to assess adverse effects. Reconstructed Human Epidermis (RHE) poses as a fascinating test system employed to assess the dermal irritation hazard potential of chemicals. Although several RHE models are reported in the OECD Test Guideline No. 439, the OECD Document No. 220 encourages the scientific community to develop and validate new RHE test systems due to its relevance for socio-economic advancement. MethodsFollowing the criteria documented in the OECD No. 220, a blind study for skin irritation (OECD 439) was conducted employing the Minimum List of Reference Chemicals for Determination of Reproducibility and Predictive Capacity using ES®-RHE. Structural and functional characteristics were assessed alongside the prediction model. ResultsThe model has shown reproducibility of optical density and barrier function, similarly to internationally validated methods. Furthermore, it shows the cell layers' development and differentiation ability due to Cytokeratin14, Cytokeratin10, and filaggrin expression. The prediction model resulted in sensitivity, specificity and accuracy rates of 100, 70, and 77 %, respectively. ConclusionsThe ES®-RHE demonstrated reliability and relevance, with similar structural and functional characteristics comparable to internationally validated models, in addition to the accepted predictive capacity according to OECD required minimum criteria, thus confirming the suitability of the national ES®-RHE in the hazard prediction of dermal irritation based on OECD Test Guideline No. 439.

Study of Life Feed in Cantang Grouper Hatcheries (Epinephelus fuscoguttatus x Epinephelus lanceolatus)

Abstract Cantang grouper (Epinephelus fuscoguttatus x Epinephelus lanceolatus) is a cross between female tiger grouper (Epinephelus lanceolatus) and male tiger grouper (Epinephelus fuscoguttatus), according to statistical data from the Ministry of Maritime Affairs and Fisheries (KKP) it has a production value of 4,406 tons in 2022 and experienced an increase in growth of 33.92%. Fulfilling this need can be done by maximizing the hatchery process, the key to which is natural food, namely for broodstock (flying fish, tuna and squid) and larvae (chlorella, artemia, rotifers, rebon shrimp). The aim of this article is to study natural feed in the hatchery of cantang grouper (Epinephelus fuscoguttatus x Epinephelus lanceolatus). This study was conducted at the Pecaron Brackish Water Aquaculture Fisheries Center (BPBAP), Situbondo, East Java on 19 June - 19 August 2023. The work method used was a descriptive method with primary and secondary data collection. The study results showed that the Hatching Rate (HR) was 73.25%, the Survival Rate (SR) was 15.98%, the Specific Grow Rate (SGR) was 0.24 g/day. Water quality measured is temperature ranging from 28-30°C, pH between 7.78-8.44, salinity between 31-32 ppt, dissolved oxygen (DO) between 5.72-6.20 mg/L, ammonia between 0.001-0.031 mg/L, nitrite is 0.001 mg/L. Natural feed has complete amino acids, fatty acids, enzymes and minerals which function in the maturation of the parent gonads and larval growth.

Massive Quiescent Disk Galaxies at 0.5 ≤ z ≤ 1 in CANDELS: Color Gradients and Likely Origin

A rare population of massive disk-dominated quiescent galaxies has recently drawn much attention, which intrudes the red sequence (RS) population without destroying the underlying stellar disks. In this study, we have carefully identified 48 RS, disk-dominated galaxies with M * > 1010 M ⊙ between redshift 0.5 and 1.0 in all five CANDELS fields. These galaxies are well fitted by a two-component bulge plus disk model, and have the bulge-to-total ratio B/T < 0.4 in the both F814W and F160W bands. The fitting results indicate that these galaxies generally have extended stellar disks (∼3 kpc on average) and tiny bulge components (∼0.5 kpc on average). To understand their possible origins, we have also selected two control samples of 156 green valley (GV) and 309 blue cloud (BC) disk-dominated galaxies according to the same selection criteria. We study the UVI(U − V versus V − I) color gradients of these galaxies to infer their specific star formation rate (sSFR) gradients out to the maximum acceptable radii. We show that on average the disks in disk-dominated RS galaxies are fully quenched at all radii, whereas both the BC and GV disks are not fully quenched at any radii. We find that all the BC, GV, and RS disk galaxies generally have nearly flat sSFR profiles. We propose a potential formation mechanism, acknowledging that various other mechanisms (e.g., central compaction and active galactic nucleus feedback) might contribute, where massive quiescent disk-dominated galaxies are predominantly formed via a process of secular disk fading.

Effects of Low-Dose X-Ray Exposure on Hematological Parameters In Vivo

Background: High levels of IR are known to induce cancer and disrupt biological processes through oxidative damage primarily driven by reactive oxygen species (ROS) overproduction. This study aims to investigate the effects of low-dose X-ray exposure on Hematologic parameters in Wistar albino rats, contributing to the limited literature on low-dose X-ray exposure and its impacts on liver health. Methods: Adult male Wistar albino rats, averaging 150 ± 25 g, were divided into four experimental groups. The rats underwent irradiation using a 6 MV linear accelerator, and blood samples were collected for biochemical analysis. Hematologic parameters, including Red Blood Cells (RBCs), platelets (PLTs), hemoglobin (Hb), white blood cells (WBCs), lymphocytes (LY), and granulocytes (GRAN), were assessed. Results: Significant variations in hematologic parameters were observed based on the method and dosage of radiation. The RBC count decreased from 9.15 ± 0.21 (control) to 3.32 ± 0.25 (higher dosage), a reduction of 58.93%. Platelet counts dropped by 51.43% and 32.46% for single and fragmented dosage approaches, respectively. Moreover, WBC and granulocyte counts were significantly reduced, with hemoglobin levels declining by 47.52% and 57.34% following specific irradiation rates (p &lt; 0.001). Conclusion: The findings underscore the adverse effects of ionizing radiation on hematologic parameters, indicating that low-dose X-ray exposure does not promote an adaptive response in hematology when followed by higher radiation doses.