Specific Quality Research Articles

The Effect of Hypnotherapy Methods On The Quality Of Life Of Menopausal Women Through The Assessment Of The Menopause Specific Quality Of Life (Menqol) Modification Scale And Serotonin Biomarkers

Objective: This study was conducted to measure the potential of hypnotherapy in improving the quality of life of menopausal women, through an assessment study of the Menopause Specific Quality of Life (MenQoL) and Serotonin modification scale. Materials and Methods: The study uses a quasi-experimental design with a pretest-posttest group control approach. Data collection in Malang with menopausal female respondents (45-60 years old), treatment group 75 and control 75. Implantation is carried out 2 times with an interval of 4 mg. It will be carried out from March 2023 to May 2023. Results: Results of the assessment of the MenQoL modified scale questionnaire (44 items) with 30 respondents: The validity test of the questionnaire with an r value between 0.958-0.998 (meaning: Valid) and the reliability test (Cronbach's Alpha) r = 1.00 (meaning: Very High). Results of the Hypnotherapy Effect test on MenQoL (wilcoxon): p-value 0.000 (significantly different) in the experimental group and p-value 0.357 (no significant difference) in the control group. Results of the Hypnotherapy Effect test on Serotonin Biomarkers (wilcoxon test): p-value 0.000 (significantly different) in the experimental group and p-value 0.219 (no significant difference) in the control group. The results of the difference (∆) between the pre and post averages: MenQoL experiment -31.58 < MenQoL control 3.95 and Serotonin experiment -2,733.48 < Serotonin control 51,241.92. Results of the normalized gain test (strength) of MenQoL with decreasing value (improvement): 86.6% of the experimental group and MenQoL with increased value (deterioration): 57.3%. Serotonin with increased values (improvement): 100 % of the experimental group and Serotonin with decreased values (improvement): 52 %. Conclusion: Hypnotherapy provides improvement in the quality of life of menopausal women through improvement of MenQoL and improvement of Serotonin biomarkers.

Enhancing Power and Thermal Gradient of Solar Photovoltaic Panels with Torched Fly-Ash Tiles for Greener Buildings

Solar photovoltaic (PV) panels that use polycrystalline silicon cells are a promising technique for producing renewable energy, although research on the cells’ efficiency and thermal control is still ongoing. This experimental research aims to investigate a novel way to improve power output and thermal performance by combining solar PV panels with burned fly-ash tiles. Made from burning industrial waste, torched fly ash has special qualities that make it useful for architectural applications. These qualities include better thermal insulation, strengthened structural integrity, and high energy efficiency. Our test setup shows that when solar PV panels are combined with torched fly-ash tiles, power generation rises by 7% and surface temperature decreases by 3% when compared to standard panels. The enhanced PV efficiency is ascribed to the outstanding thermal insulation properties of fly ash tiles and their capacity to control panel temperature. To ensure longevity and safety in building applications, the tiles employed in this study had a water absorption rate of 5.37%, flexural strength of 2.95 N/mm2, and slip resistance at 38 km/h. Furthermore, we find improved structural resilience and lower cooling costs when up to 30% of the sand in floor tiles is replaced with torched fly ash, which makes this method especially appropriate for sustainable buildings. Key performance indicators that show how effective these tiles are in maximizing energy use in buildings include thermal emissivity (0.874), solar reflectance (0.8), and solar absorption (0.256). While supporting more ecofriendly building techniques, this study highlights the advantages of utilizing burned fly ash in solar PV systems: enhanced power generation and thermal comfort. The main results open a greater potential for fly ash use in different building materials. The use of torched fly ash in building materials enhances thermal insulation and structural integrity while lowering cooling costs, making it an ideal choice for eco-friendly construction and highlighting the potential for further research into environmentally responsible, energy-efficient solutions.

Application of Mass Spectrometry for Analysis of Nucleobases, Nucleosides and Nucleotides in Tea and Selected Herbs: A Critical Review of the Mass Spectrometric Data.

The main and most commonly known biological function of nucleobases, nucleosides, and nucleotides is usually associated with the fact that they are the building blocks of nucleic acids. However, these compounds also belong to plant secondary metabolites, although in that role they have attracted less attention than the others, e.g., terpenes, phenolics, or alkaloids. The former compounds are also important constituents of the human diet, e.g., as ingredients of tea and herbs, endowing them with specific taste qualities and pharmacological activities. Liquid chromatography-mass spectrometry seems to be the most important analytical method that permits the identification and determination of nucleobases, nucleosides, and nucleotides, along with the other metabolites. The main goal of this review is to discuss in detail the aspects of mass spectrometric detection of nucleobases, nucleosides, and nucleotides in tea and selected herbs. An important conclusion is that the identification of the compounds of interest should be performed not only on the basis of [M + H]+/[M - H]- ions but should also be confirmed by the respective product ions; however, as discussed in detail in this review, it may sometimes be problematic. It also clear that all difficulties that may be encountered when analyzing plant material are caused by the complexity of the analyzed samples and the need to analyze different classes of compounds, and this review absolutely does not debase any of the mentioned papers.

Democratic Revisability and the Legitimacy of Constitutional Entrenchments: A Content-Specific Approach

Abstract As modern constitutions bind democratic legislation to entrenched norms, they are in tension with the democratic idea that laws should be open to revision by new majorities. Against a widespread view, constitutional norms cannot be considered to be “more democratic” than ordinary laws due to specific qualities of the constitution-making process. Rather, the higher-level law of constitutions can fulfil a specific function as it may provide standards that ensure that laws made by the majority can be justified to everyone. On that basis, I evaluate for different types of constitutional norms whether there are good reasons for constraining legislation. In particular, entrenching cultural traditions and economic policy is more problematic than guarantees of the democratic process and rights ensuring respect for individuals. In sum, a two-tiered law-making system has important values, but people engaging in constitution-making and constitutional interpretation should be wary that the constitutional form is not abused.

Analytical Validation of Cxbladder® Detect, Triage, and Monitor: Assays for Detection and Management of Urothelial Carcinoma.

Background: Cxbladder® assays are reverse transcription-quantitative polymerase chain reaction (RT-qPCR) tests incorporating five genetic biomarkers (CDK1, MDK, IGFBP5, HOXA13, and CXCR2) to provide risk stratification for urothelial carcinoma (UC) in patients with hematuria or undergoing surveillance for recurrent disease. This study evaluated the analytical validity of the Cxbladder Detect, Triage, and Monitor assays. Methods: Pre-specified acceptance criteria, including the assays' fundamental aspects (sample and reagent stability, RNA extraction quality, RT-qPCR linearity, and analytical sensitivity and specificity), accuracy and precision, and reproducibility between laboratories. Results: Cxbladder had an analytical sensitivity of 12.5-31.1 RNA copies/mL urine for the CDK1, MDK, IGFBP5, and HOXA13 UC biomarkers and 68.9 RNA copies/mL for the inflammatory biomarker CXCR2. All the pre-specified analytical criteria were met. Cxbladder had diagnostic sensitivity, specificity, positive predictive value, and negative predictive values of 77%, 94%, 68%, and 96%, respectively, for Detect; 95%, 46%, 20%, and 98% for Triage; and 91%, 39%, 21%, and 96% for Monitor. Cxbladder had high analytical accuracy (≤10.63% inaccuracy across all biomarkers) and good reproducibility (>85% concordance between laboratories). Conclusions: Cxbladder accurately and reproducibly detects UC biomarker expression and can aid clinicians in risk stratification of hematuria patients or those undergoing surveillance for recurrent UC.

Топологические изоляторы в электронных и спинтронных устройствах

Background: Topological insulators (TIs) are materials with distinctive features, including insulating interiors and conducting surface states protected by time-reversal symmetry. These features make TIs extremely promising for electrical and spintronic device applications, where manipulating electron spin without charge transfer is advantageous. Objective: This study aims to investigate of TIs to improve the performance and efficiency of electrical and spintronic devices. We look at the special qualities of TIs that may be used to improve device functionality, such as reduced power consumption and higher operational speed. Methods: To investigate electron transport behaviour on the surfaces of different TIs, we used a mix of quantum mechanical models and experimental settings. Devices based on bismuth telluride (Bi2Te3) and thallium arsenide (TlAs) were built to test their performance in real-world applications. Results: TI devices showed considerable gains in spin transport efficiency and thermal stability compared to conventional materials. Spintronic devices based on TIs demonstrated a 50% reduction in energy usage and a 30% improvement in data processing speed. Conclusion: Including topological insulators in electrical and spintronic devices offers a promising path to more efficient and speedier technologies. Future research should concentrate on the scalable integration of TIs into commercial devices and the discovery of novel materials with topological insulating characteristic.

Deep Eutectic Solvents Enhancing Drug Solubility and Its Delivery.

Deep eutectic solvents (DES) are environmentally friendly solvents with the potential to dissolve bioactive compounds without affecting their characteristics. DES has special qualities that can be customized to meet the unique characteristics of a biomolecule/active pharmaceutical ingredient (API) in accordance with various therapeutic needs, providing a reliable approach in opening the door for the creation of cutting-edge drug formulations by resolving solubility issues in pharmaceutics. This study outlines newly developing approaches to solve the problem of inefficient API extraction due to poor solubility. These emerging strategies also have the capacity to alter the chemical and physical stability of API, which triggers drug's shelf life and their possible health benefits. It is anticipated that the highlighted methods and processes will be developed to capitalize on the DES potential to improve drug solubility and delivery in the pharmaceutical sector.

Development of Symptom Specific Dysphagia Quality of Life Questionnairein Tamil.

Swallowing intricately involves sensorimotor systems, pivotal for integrating upper digestive and respiratory functions. Dysphagia, challenging swallowing, often precipitates anxiety and depression, deeply affecting the quality of life (QOL). Understanding patient-centric symptoms is vital for assessing dysphagia's QOL impact. This study aimed at developing and validating the Symptom Specific Dysphagia Quality of Life Questionnaire in Tamil (SSDQOL-T). SSDQOL-T was developed in Tamil and underwent rigorous content validation. This questionnaire was administered to 120 normal individuals and 32 dysphagia patients, assessing various swallowing difficulties and their QOL impact. Results indicate SSDQOL-T's good internal consistency (Cronbach's α = 0.78). Significant differences in swallowing ability and QOL were noted across age groups, with older adults experiencing heightened symptoms. A high significance in mean score was obtained between healthy adults and dysphagia across all sub-domains with a 'p-value' of 0.0005. Symptoms that were found to have high significance were cough/gag reflex, regurgitation, odynophagia, globus sensation, heartburn and tiredness when compared between mechanical and degenerative dysphagia group. Strong correlations were found between SSDQOL-T scores and the Dysphagia Handicap Index in Tamil (r = 0.89). The SSDQOL-T questionnaire provides a robust tool for evaluating dysphagia-related QOL in the Tamil-speaking population. Its validation underscores its clinical relevance and utility for understanding the multidimensional impact of dysphagia. This study emphasizes the importance of culturally sensitive assessment tools in comprehensively evaluating dysphagia's QOL implications.

The Intermediary Role of Electronic Word of Mouth in the Relationship Between Digital Marketing Techniques and Purchasing Behaviour to Enhance Decent Work and Economic Growth: A Survey of Students at the University of Mosul

Purpose: An analysis of the digital marketing techniques literature shows growing of these techniques among students at the University of Mosul. In order to achieve this goal, the study model was designed initially to address changes and competitive challenges. Therefore, this research aims to study the effect of using digital marketing techniques on purchasing behavior through the mediating role of electronic word of mouth (e-WOM) to support the achievement of the Sustainable Development Goals. Design/methodology/approach: The descriptive analytical approach was adopted to test the proposed model of technique whose validity was verified using survey data from (350) individuals. This study used (Amos 24) which is a structural equation modeling (SEM) software and a statistical technique to assess factor relationships. Results: The results of the study variables and their dimensions indicate that there is a significant impact relationship between digital marketing techniques and purchasing behavior. There is also a significant impact relationship between digital marketing techniques and e-WOM. There is also a significant impact relationship between e-WOM and purchasing behavior. There is a significant impact of digital marketing techniques on purchasing behavior through the mediating role of e-WOM. This indicates the ability of the study sample individuals to diagnose and know the concepts adopted by the study and attempt to diagnose them through the field aspect. Originality/Value: The identified factors play a major role in individuals' intentions towards using digital marketing techniques in purchasing behavior through the mediating role of e-WOM. The results of this study contribute to helping individuals build their needs and desires with high quality and distinct specifications.

ThP3.12 - Assessing Photo-documentation Compliance in Oesophago-Gastroduodenoscopy: A Review of Adherence to BSG and AUGIS Recommendations

Abstract Aim In 2017, the British Gastroenterology Society (BSG) and the Association of Upper GI Surgeons of Great Britain and Ireland (ASGBI) issued a position statement outlining specific quality parameters for oesophago-gastroduodenoscopy (OGD), including photo-documentation of eight specified anatomical sites. This audit assesses the appropriate utilization of photo-documentation for diagnostic OGD. Methods A retrospective analysis of diagnostic OGD preformed in a single centre. General surgeons, gastroenterologist and nurse endoscopists performed OGDs. Patient with incomplete OGD or those carried out for therapeutic purposes were excluded. OGD report included photo-documentation was analysed. Results 250 OGD were included; 54.8% were male and median age was 61 years. Indications for OGD were: 28% for nausea/vomiting, 26% for dysphagia, 22.4% for upper GI bleed, 12.4% for abdominal pain, 12% for anaemia, 11.2% for weight loss and 8.4% for dyspepsia. 62% of OGDs had photo-documentation: 9.6% upper oesophagus, 45.2% gastro-oesophageal junction, 36.8% fundus in retroflexion, 26% body of stomach, 8% incisura in retroflexion, 30.8% antrum, 17.2% duodenal bulb and 36% distal duodenum. Overall, 1.2% of OGDs had all eight anatomical sites photo-documented, all by the same endoscopist. Conclusion Robust photo-documentation plays a crucial role in ensuring both accurate clinical assessments and meeting medico-legal requirements. Our audit indicates that the current level of photo-documentation in OGD is less than optimal. Enhancing endoscopist education and raising awareness about recommended practices may lead to improved results. Further research is imperative to explore the underlying factors contributing to suboptimal photo-documentation, fostering a deeper understanding and facilitating targeted interventions for improvement.

An Analysis Of Energy And Nutrient Content In High Energy Natural Isotonic Drink (Isopower)

Isotonic drink is the carbonated or non-carbonated drink product used to subtitute the fluid lost in the body. Lack of fluid in the body can cause muscle fatigue until causing the performance decrease in athlete. Isotonic drink can accelerate the return of body fluid compared to water. The purpose of this research was to analyze the content of energy, sodium, potassium, and Vitamin C in isotonic drink with raw material coconut water, pure coconut oil, bee bread, palm vinegar, and honey as high energy natural istotonic drink. The research design used was descriptive observation based laboratory test. The data analysis employed SPSS 22 programs namely by carrying out descriptive test until obtained the average for each isotonic namely 247,491 kkla, sodium 77,085 mg.kg, potassium 1000,785 mg/kg and Vitamin C 2,112 mg. This research concluded that the energy drink content has fulfilled the quality specification of isotonic drink, while the sodium and potassium level do not fulfill the quality specification of isotonic drink yet. Likewise with the Vitamin C content which also does not fulfill the Referrence of Nutrition Label namely 10%.

“When I Spoke, I Spoke From the Heart”: Empirical Insights and Therapeutic Lessons From an Indigenous Counseling Center

Indigenous Peoples in Canada experience inequities in behavioral health outcomes stemming from colonial subjugation, including tacit cultural assimilation through health care. Indigenous communities assert that culturally commensurate health interventions improve wellbeing. This study, conducted with clients and staff at a First Nations behavioral health treatment program, sought to identify how respondents conceived of the therapeutic endeavor with respect to possibilities for remedying colonial injuries such as the abuses of the Indian Residential Schools (IRSs). Thematic analysis of 32 interviews revealed that targeted therapeutic goals as well as specific counselor qualities were important for a positive therapeutic experience for those in the program. Ultimately, assimilative practices, such as the IRSs of the past and mainstream behavioral health treatment programs in the present may collectively contribute to the continuation of inequities in health outcomes for Indigenous Canadians. Decolonizing the therapeutic endeavor offers a potential avenue for positive change.

Designing, delivering and evaluating a specialty specific quality improvement course for the rheumatology multidisciplinary team

Abstract Objectives Quality improvement (QI) methodology aims to drive improvement in healthcare using a systematic approach. QI is an integral part of healthcare professional training curricula. However, many members of the rheumatology community have not accessed formal QI methodology training, including those expected to supervise QI activity. The BSR QI practical methodology workshop was created to address this knowledge gap in a specialty-specific course designed and delivered by, and for, the multidisciplinary team. Methods Course design centred on the Institute for Healthcare Improvement approach, ‘Model for improvement’, adapting materials from the well-established Trainees Improving Patient Safety through QI (TIPSQI) initiative. The course was delivered online (2021) and face-to-face (2022). Kolbs’ four stage experiential learning cycle informed course design utilising rheumatology-specific cases and facilitated breakout rooms to teach QI tools. Kirkpatrick’s four-stage model was used to design the course evaluation. Data from surveys completed before, immediately after, and six months’ following the courses were used to evaluate the course. Results Baseline knowledge of specific QI tools was limited. Post course evaluation demonstrated increased confidence to use and teach tools. Sustained confidence to contribute to and lead QI activity was reported. Course satisfaction was high; 100% of delegates would recommend the course to colleagues. Conclusion This successful, rheumatology specific QI course led to improved delegate knowledge of QI methodology and confidence in leading and teaching QI initiatives. It has contributed to building momentum in a growing rheumatology QI community of practice and to embedding a sustainable culture of improvement across the rheumatology community.

Maternal Depressive Symptoms and Children’s Behavioral Problems: The Moderating Roles of Emotion Regulation and Teacher-Student Relationship Quality

The detection rate of children’s behavioral problems is on the rise throughout the world, reaching 18.8% in China. Maternal depressive symptoms is one of the main causes of children’s behavioral problems. Our study explored the moderating roles and the specific moderating mechanism of children’s emotion regulation and teacher-student relationship quality in the association between maternal depressive symptoms and children’s behavioral problems based on the resilience framework and the multiple moderating model. A cross-sectional survey on mothers and teachers of Chinese primary school students in grades 1 to 3 in suburban Beijing was conducted to investigate children’s behavioral problems, emotion regulation, teacher-student relationship quality, maternal depressive symptoms, and demographic characteristics (n = 300) in this study. Pathway analysis and the Johnson-Neyman method were used to determine the moderating roles and the specific moderating mechanism of emotion regulation and teacher-student relationship quality. Results showed that emotion regulation and teacher-student relationship quality played moderating roles in the association between maternal depressive symptoms and children’s behavioral problems and the moderating mechanism was the additive moderating model. To be specific, emotion regulation and teacher-student relationship quality played moderating roles parallelly. Emotion regulation could moderate the negative effect of maternal depressive symptoms on both internalizing and externalizing behavioral problems in children. Meanwhile, teacher-student relationship quality could moderate the negative effect of maternal depressive symptoms on children’s externalizing behavioral problems. The study highlighted the value of children’s emotion regulation and teacher-student relationship quality against adverse family environments and gave an orientation for intervention.

A robust assessment method of point cloud quality for enhancing 3D robotic scanning

Point clouds are widely used to construct models of workpieces using 3D scanners, especially where high-quality robotic and automatic 3D scanning is required in industries and manufacturing. In recent years, Point Cloud Quality Assessment (PCQA) has garnered increasing attention as it provides quality scores for entire point clouds, addressing issues such as downsampling and compression distortions. However, current PCQA methods cannot provide specific and local quality scores, which are necessary to facilitate rescanning and recompletion in 3D robotic scanning. Additionally, 3D data produced by robotic view-planning algorithms are usually considered the final result, where PCQA is typically not involved. In this paper, we bridge the gap between PCQA methods and practical robotic 3D scanning. We propose a no-reference PCQA method that recognizes sparse regions during 3D scanning, providing both local and overall quality scores. Unlike traditional methods that primarily consider density as a key metric, our method assumes that an expected 3D scan will have a uniformly distributed point cloud on surfaces. We analyze the quality of points by using geometric information from surfaces fitted to these points, which are mapped to a 2D distribution based on specified distances and angles. We conducted experiments on various datasets, including both synthetic and public datasets, to evaluate the accuracy and robustness of our method. The results show that our method can represent the quality on surfaces more accurately and robustly than density calculation methods. Additionally, it outperforms most existing PCQA methods in scenarios of downsampling, which is a common challenge in high-quality 3D scanning applications. The performance of our quality enhancement experiments on practical 3D scanning, conducted towards the end of our study, demonstrates significant potential for real-world applications. The related code is released at https://github.com/leihui6/PQA.

Use of New and Light Materials in Automotive Engineering for Towing System

Towing systems are an important component in the automobile industry, having to meet specific quality and resistance conditions. In most cases, the towbar is made of steel. Decreases in vehicle weight and manufacturing price mean that, in this field, research is also being conducted in order to replace the materials that make up the towbar and replace the steel with composite materials or aluminum alloys. In this paper, research was performed on towing systems built from other materials, and the obtained results were compared with those of steel systems. Theoretical calculations and experimental results made it possible to obtain a database and recommendations for the use of new and composite materials. The experimental tests validated the theoretical results obtained. Five towing systems made of different materials were studied. The results of the research are emphasized through recommendations regarding the manufacturing of towing systems.

Identifying Applications of Wood Ash by Matching Its Characteristics with End-User Quality Requirements: A Case Study

Despite being a bio-based material, wood ash generated by pulp and paper mills is mainly landfilled in Canada. This is because it is perceived as waste material and the certification requirements and regulations controlling its use are complex. To promote wood ash utilization, ash samples from mills in British Columbia (BC), Canada were characterized, and the properties were compared to quality specifications for potential applications. Three types of ash samples were collected: bottom ash, multi-clone (MC) ash, and electrostatic precipitator (ESP) ash. The characteristics of each type of ash were analyzed, and their suitability for various applications was determined. The study found that ESP ash had a higher calcium carbonate equivalent (CCE) value than MC ash, making it more useful as a liming material in agricultural land. The study identified quality criteria for industries where wood ash can be used, such as construction, agriculture, composting, stabilization/solidification, liming, mining, and fire-retardant. Each type of ash was evaluated for its use in these industries, and the environmental regulations for each application were considered. It was observed that the quality criteria for one application could differ dramatically from those for another. Intuitively, an ash producer would cross-check the characteristics of their ash types against the quality requirements for potential uses near the ash source because different applications have different quality requirements This article is believed to help identify promising applications of ash thereby removing ash from landfilling and promoting the circular economy.

405. SELECTIVE ANTERIOR GASTROPEXY WITH OR WITHOUT FUNDOPLICATION FOR THE TREATMENT OF GRADE III/IV HIATAL HERNIA

Abstract Background The optimal approach to a paraoesophageal hernia (PEH) repair is unclear. Several steps during the procedure are still for discussion. Most surgeons dealing with PEH surgery agree on removal of the hernia sac from the mediastinum and a hiatoplasty with non-absorbable suture. Whether to perform an anti-reflux procedure or/and a gastropexy is unclear. Few studies exist on the subject but without clear favor of an anti-reflux procedure and/or a gastropexy. The aim of this upcoming study is to test if the anti-reflux procedure is redundant for patients suffering from PEH with obstructive rather than regurgitation symptoms. Methods We are setting up a pragmatic, prospective, multicentre, two-armed study. Study beginning June 2024. Sample size calculation with 108 patients in each arm. Both arms will do hernia sac excision, closure of hiatus and gastropexy. One arm will in addition do an anti-reflux procedure. Our objectives are 1) To assess safety of anterior gastropexy with and without fundoplication regarding peri- and postoperative complications. 2) To compare efficacy of anterior gastropexy with and without fundoplication regarding symptom control and clinical recurrence. 3) To assess health related quality of life pre- and post-surgery in patients treated with the two strategies for PEH. Results Our primary outcome is disease specific and health related quality of life before surgery and 3-6-12 months after surgery. Secondary outcomes are per- and post-operative complications according to the clavien-dindo score and radiological status/recurrence 12 months after surgery. Conclusion The study will add on to existing knowledge about essential technical steps of PEH surgery. Do the patients benefit from a fundoplication or is this potentially complicating procedure redundant regarding long-term symptom control.

Preharvest applications of monopotassium phosphate to improve fruit quality and volatilome composition in cold-stored cherry tomatoes

The experiment addressed the effects of preharvest KH2PO4 foliar spraying (20 mmol · L−1) on fruit quality and composition (including volatile organic compounds, VOCs) of cherry tomatoes (‘Caravaggio’, ‘Sugarland’ and ‘Top Stellina’) after 0 (S0), 7 (S7) and 14 days (S14) of storage at 8.0 °C. On the average of the 3 genotypes, the KH2PO4 treatment improved fruit pressure firmness, total soluble solids (TSS), titratable acidity (TA), total phenols and carotenoids concentrations, along with the fruits' antioxidant capacity (by up to 17% for FRAP assay). Within the S7–S14 period, control fruits showed the highest reductions in TSS, TSS/TA ratio and total carotenoids (−17, −12 and −45, respectively), whereas treated fruits proved the strongest increase in DPPH (+12%). Sixteen out of 32 VOCs were promoted following KH2PO4 application, including the aldehydes hexanal, (E)-2-hexenal and (Z)-3-hexenal and the apocarotenoids (E)-citral, (E)-β-ionone, geranylacetone and 6-methyl-5-hepten-2-one. Proceeding from S0 to S14, several VOCs decreased more strongly in control fruits, as for hexanal (−48%∖) and total aldehydes (−42%∖, whereas at S14 treated fruits had higher concentrations of linalool, geranylacetone and 6-methyl-5-hepten-2-one (1.06, 52.50 and 79.27 μg · kg−1, respectively). ‘Caravaggio’ demonstrated the strongest apocarotenoid reduction at S14, whereas ‘Top Stellina’ was more responsive to KH2PO4 (mainly for β-cyclocitral, geranylacetone and total terpenes/terpenoids), thus highlighting the central role of the genotype in responding to other experimental factors. Nonetheless, these results suggest that proper preharvest KH2PO4 applications can preserve specific commercial, nutritional and quality traits of cold-stored cherry tomatoes.

50182 Evaluating disease specific quality of life and chemoprevention utilization in patients with more than one lifetime skin cancer

50182 Evaluating disease specific quality of life and chemoprevention utilization in patients with more than one lifetime skin cancer