Specific Ability Research Articles

YENİYETMƏ MƏKTƏBLİLƏRİN SOSİALLAŞMASI

Socialization of Teens of School for Summary Article deals with the research of school’s social effectiveness are not high enough. There is considerable discrepancy between the formal level of education and the actual level. The social effectiveness of education not only depends on the amount and quality of the knowledge people receive, but also their degree of application, the practical realization of people's labor and social activities. Education is both symbolic and practical. The practical significance of education is reflected in specific knowledge, skills and abilities. Symbolism appears in the public domain of education. Key words: socialization of education, conflict-emotional relations, teenage identity formation, “imitation” and “dentification” mechanisms, socialization

Delivery of mRNA Using Biomimetic Vectors: Progress and Challenges.

Messenger RNA (mRNA) is an emerging class of therapeutic agents for treating a wide range of diseases. However, due to the instability and low cell transfection rate of naked mRNA, the expression of delivered mRNA in target cells or tissues in vivo requires delivery strategies. Biomimetic vectors hold advantages such as high biocompatibility, tissue specific targeting ability and efficient delivery mechanisms, potentially overcoming challenges faced by other delivery vectors. In this review, biomimetic vector-based mRNA delivery systems are summarized and discuss the possible challenges and prospects of such delivery systems, which may contribute to the progress and application of mRNA-based therapy in the biomedical field.

Fencing Training with Reaction Time Lights

Authors Rafael Barañano-Alcaide Msc, PhD student for Complutense University of Madrid.(Spain). Corresponding author . rafabara@ucm.es Dr. Manuel Sillero-Quintana, Titular professor of Universidad Politécnica de Madrid (UPM), Faculty of Physical Activity and Sport Sciences (INEF), Sports Department, Madrid, (Spain). Dr. Ricardo-Bernardez, Titular professor of optometry department of the University Complutense of Madrid.(Spain). Jimena Barañano-Perez, student of I.E.S Luis de Gongora of Córdoba (Spain). Rut Gonzalez-Jiménez Msc, PhD student for Complutense University of Madrid.(Spain). Abstract Objective: evaluate different reaction times in fencing training with reaction time lights Method: This manuscript proposes four specific exercises for evaluating the simple reaction time (SRT), the elective reaction time (ERT), the go/no-go response time (G/NG) and the decision decision-making after lunge (DML), march (DMM) and braking (DMB) in fencers. The sample consisted of 48 fencers (22 males and 17 females; age: 21 ± 13 years) from several fencing clubs in the region of Andalusia, competing at amateur (10 athletes), regional (17 athletes), national (7 athletes), and international (5 athletes) in the three official fencing weapons: Epee (E), Saber (S), and Foil (F). The exercises were developed for the Queling Sport lighting system, connected by Bluetooth with the ReactionX android application, which controlled the activation of the lights and recorded the reaction time and the correction of the execution for each trial. Results: The results by gender did not show significant differences. Considering the results by weapon, the foil fencers were fastest than saber fencers, in all the exercises, but they were only significantly faster in the DML and DMM exercises. The performance in all the exercises was directly related with the competition level of the fencer, but only significantly better in foil fencers than in sable fencers when the exercise required decision-making processes. Conclusions: We propose a reference scale to evaluate the perceptive ability of the fencers that could be applied in talent detection processes and for evaluating the specific perceptive ability of the fencers.

Selective extraction of captafol from blood and river water samples using molecularly imprinted polymers

In this study, the captafol molecularly imprinted polymers were first prepared using the precipitation polymerization method, using captafol as the template molecule and acrylamide (Am) as the functional monomer. The synthesized polymers have spherical particles with a loose, porous surface, as determined through scanning electron microscopy. The polymer was analyzed using BET, Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM), and Fourier Transform Infrared Spectroscopy (FTIR). The polymers demonstrated a high adsorption efficiency of up to 90 % and specific recognition ability towards captafol, based on the results of the dynamic and static adsorption assays. The factors affecting MIPs’ binding efficiency were carefully optimized. Studies were established to analyze captafol in water and human blood serum samples under optimal conditions. Through adsorption kinetics, adsorption isotherms, and selectivity tests, this suggested approach demonstrated good MIP adsorption characteristics for captafol. The resulting Cap-MIPs showed notable selectivity for captafol as compared to folpet, high adsorption capacity (90 %), and good reusability, with the ability to reach adsorption equilibrium in less than 60 min. The results showed that the Cap-MIPs strategy exhibited high selectivity, good consistency, and high sensitivity, making it an efficient way to enrich and recognize captafol in a complex blood serum matrix.

Contributions Regarding the Improvement of Specific Physical Training in 14 – 16 Year-Old Handball Players

By carefully watching the handball games both in the domestic championship and the games from the World and European Championships, we come to the conclusion that great performances are only achieved by teams that have a very good physical training, so implicitly a general and specific motor ability excellently doubled by a preparation on training factors: technical, theoretical, tactical and psychological. The choice of plyometric exercises must imitate handball skills, to maximize the strengthening of the muscles that trigger the movement and, in certain cases, to generate "motor memory", consolidating the technical skills involved.

A NIR iridium(III) complex-based luminescence probe for imaging mitochondria pyruvate dehydrogenase kinase 1 in triple-negative breast cancer cells

The aberrant expression of mitochondrial pyruvate dehydrogenase kinase 1 (PDK1) is highly associated with tumorigenesis and metastasis of triple-negative breast cancer (TNBC). However, because of the dearth of highly sensitive and targetable probes for PDK1, the precise imaging of mitochondrial PDK1 in TNBC cells remains challenging. We herein describe the first near-infrared (NIR) luminescence probe for visualizing PDK1 in TNBC living cells through conjugating a PDK1 inhibitor, dichloroacetic acid (DCA), to an iridium(III) complexes. This probe retains not only the favorable optical characteristics of iridium(III) complexes, but also the specific binding ability of DCA for PDK1. The probe can sensitively and specifically detect mitochondria PDK1 in TNBC cells, as verified by cellular thermal shift assay (CETSA), knockdown and selectivity experiments. Moreover, complex 1 has the capability for imaging TNBC spheroids and zebrafish models with good imaging contrast and penetration, presumably benefiting from its PDK1 target ability and NIR property. Importantly, the probe shows negligible luminescence in normal cell lines with low expression of PDK1, demonstrating its ability to discriminate TNBC cells from normal cells. This probe, which acts through the interplay of both low oxygen diffusion and a rigid microenvironment upon binding to PDK1, could provide mechanistic insights into the biological roles of PDK1 in TNBC and support the development of PDK1-based TNBC diagnostic probes in vivo.

How (not) to write a B♭ french horn beginners method book

Name: Isabelle Roelofs Main subject: Master Natural Horn Research supervisor: Daniel Salbert Title: How (not) to write a Bb French Horn beginners method book Research question: How (not) to write a Bb French Horn beginners method book Summary of the results: As a horn teacher, I realize that the existing Dutch method books seem not to be written from the perspective of a beginning, young horn player. They show little consideration for the specific physical abilities of children at a young age when learning to play the horn, probably because those methods are mostly not written by a horn player. Therefore, I have researched the do's and don'ts behind writing a method book. If playing the exercises in a method is not physically feasible, it can lead to frustration for the student, which, in my opinion, is detrimental to the learning process. I have always learned that moments of success are crucial for the development and maintenance of motivation. I find these moments of success lacking in existing Dutch-language horn methods. I also believe that they progress too quickly to emphasize reading notation. I notice that my own students often prioritize correctness over musicality. I have critically examined and compared the available Dutch horn method books. Additionally, I interviewed fellow horn teachers to gather their perspectives. Furthermore, I attended a lesson for young horn players at BASIS (Royal Conservatory of the Hague) where auditory learning takes precedence. I am not the first to consider writing my own method. Other horn teachers have embarked on this journey, each with their unique motivations. My research has revealed that I am not the only one who has critical thoughts about the existing horn method books. A significant part of the interviewed teachers also emphasized this same point. Based on the obtained results, I have outlined the initial steps that, in my opinion, are necessary for a starting young horn player, along with the corresponding range of tones. Biography: Isabelle Roelofs, an accomplished horn player and dedicated music teacher, earned degrees in French Horn and Music Education from Codarts University. Graduating with honors from the Royal Conservatory of Antwerp, she is currently pursuing a Master's in Natural Horn at The Hague Conservatory with Teunis van der Zwart. Isabelle is the founder of Belle Musique (2018), where she imparts her musical knowledge through personalized horn lessons, shaping the future of horn players step by step.

Evaluation of the Stereochemistry of Staphyloferrin A for Developing Staphylococcus-Specific Targeting Conjugates.

Bacteria in the genus Staphylococcus are pathogenic and harmful to humans. Alarmingly, some Staphylococcus, such as methicillin-resistant S. aureus (MRSA) and vancomycin-resistant S. aureus (VRSA) have spread worldwide and become notoriously resistant to antibiotics, threatening and concerning public health. Hence, the development of new Staphylococcus-targeting diagnostic and therapeutic agents is urgent. Here, we chose the S. aureus-secreted siderophore staphyloferrin A (SA) as a guiding unit. We developed a series of Staphyloferrin A conjugates (SA conjugates) and showed the specific targeting ability to Staphylococcus bacteria. Furthermore, among the structural factors we evaluated, the stereo-chemistry of the amino acid backbone of SA conjugates is essential to efficiently target Staphylococci. Finally, we demonstrated that fluorescent Staphyloferrin A probes (SA-FL probes) could specifically target Staphylococci in complex bacterial mixtures.

Bismuthene nanosheets as a photodynamic and photothermal antibacterial agent under NIR light illumination

Bacterial infections remain a significant public health burden due to the emergence of antibiotic resistance and their non-specific cytotoxic effects, leading to the search for novel antibacterial agents. Two-dimensional (2D) pnictogens, which stand out with their advantegeous properties such as large surface areas, compatibility with biological systems, and permeability across biological membranes, have emerged as potential materials in the fight against bacterial infections. By considering all these advantages, here for the first time, the antibacterial activity of 2D bismuth (Bismuthene, Biene) on Gram-negative Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa), Gram-positive Staphylococcus aureus (S. aureus) and Methicillin-Resistant Staphylococcus aureus (MRSA) were examined under NIR light illumination. A growth curve analysis was conducted with a concentration of 256 μg*mL−1 of exfoliated Biene nanosheets to assess the inhibition effect and corresponding antibacterial effect (%) against each bacterial strain. The photodynamic theraphy (PDT) and photothermal therapy (PTT)-mediated antibacterial mechanisms were explored by analyzing the generation of reactive oxygen species (ROS) via Glutathione (GSH) oxidation assay while a photothermal camera monitored temperature dynamic changes during irradiation. The high specific surface area-dependent membrane damage ability of Biene and morphological changes of the bacteria were visualized by field emission scanning electron microscope (FESEM). The exciting growth inhibition activity of Biene nanosheets for all bacterial strains was increased during irradiation, and breathtakingly the inhibition rate reached up to ≥ 99.1 % for P. aeruginosa, S. aureus, and MRSA. Besides, S. aureus and MRSA are more susceptible to Biene than E. coli and P. aeruginosa.

Resilience and tolerance to uncertainty among military journalists in new information and communication conditions

RELEVANCE. In the conditions of constant, constantly changing wars, hostilities and armed conflicts, the role of military journalists, or war correspondents, who broadcast to the whole world from the battlefield, transmit timely and high-quality information from battlefields. These are professionals who are subject to many demands in terms of psychological qualities, resilience and tolerance for uncertainty. A person who does not possess such qualities cannot perform this extremely dangerous and traumatic work. In addition, military journalists are under pressure in modern information and communications conditions, which makes their already difficult work more difficult. At the same time, at the moment there is very little research on the topic of what specific qualities and abilities war correspondents should have to successfully carry out their professional activities. The purpose of the study is to study the factors of resilience and tolerance of uncertainty among military journalists.MATERIALS AND METHODS. An empirical study was conducted on the resilience and tolerance of uncertainty of 54 war correspondents and 50 journalists who are not involved in covering military events. We studied used the methods of “Vitality Test” by D.A. Leontyev and E.I. Rasskazova and “Uncertainty Tolerance Scale” by T.V. Kornilova.RESULT AND DISCUSSION. Statistically significant differences in indicators of resilience and tolerance to uncertainty were identified between groups of war correspondents and journalists, and significant relationships between indicators of resilience and tolerance to uncertainty in groups of war correspondents and journalists were identified and described.CONCLUSION. The conducted research makes it possible to form a picture of what personal characteristics war correspondents have and to highlight those traits that help them cope with dangerous and stressful working conditions

Application of molecularly imprinted polymers in the water environmental field: A review on the detection and efficient removal of emerging contaminants

The emerging contaminants in the environment pose a threat to ecological security and human health. At present, traditional technologies are difficult to detect and remove existing trace emerging contaminants in water bodies. Therefore, efficient removal of low concentration emerging contaminants is a key issue in ensuring water safety. As an emerging technology, molecular imprinting technology (MIT) can synthesize polymers with specific recognition ability for target pollutants, providing a new approach for efficient removal of emerging contaminants. It is worth noting that combining MIT with traditional catalysts is an effective method to improve detection limits and removal efficiency. This review mainly introduced the research progress of using MIT to detect pollutants in various sensors and using advanced oxidation technology to remove pollutants in recent years, focusing on the preparation and application of MIT-based photocatalysts, electrocatalysts, and Fenton-like catalysts. In addition, possible interactions between the target analyte and MIT were discussed, as well as the reusability and stability of imprinted catalysts in water treatment, and their potential ecological toxicity risks were analyzed. Finally, the challenges of MIT based pollutant mitigation and the application prospects of molecular imprinting technology in environmental analysis were elaborated from multiple perspectives.

A comparative study on cadmium tolerance and applicability of two Solanum lycopersicum L. cultivars.

Solanum lycopersicum L. can be classified into low Cd-accumulating and high Cd-accumulating types based on their accumulation characteristics of cadmium (Cd). There are many common S. lycopersicum varieties available in the market, but their specific Cd tolerance and enrichment abilities are not well understood. This article uses two S. lycopersicum cultivars, Yellow Cherry and Yellow Pearl, as experimental materials. The experimental method of soil pot planting was adopted, and Cd concentrations in the soil were added at 0, 0.6, 1.5, 2.5, 5, and 10 mg/kg. The changes in Cd content, biomass, photosynthetic pigment content, and photosynthetic parameters of the two S. lycopersicum cultivars were analyzed to screen for low-accumulation S. lycopersicum cultivars. The results showed that S. lycopersicum are Cd-sensitive plants. The Cd accumulation, photosynthetic parameters, and other basic indicators of Yellow Cherry basically showed significant differences when the soil Cd concentration was 0.6 mg/kg, and the biomass showed significant differences when the soil Cd concentration was 1.5 mg/kg. Except for the Cd accumulation in the roots and leaves of Yellow Pearl, which showed significant differences at a soil Cd concentration of 0.6 mg/kg, the other indicators basically showed significant differences when the soil Cd concentration was 1.5 mg/kg. When the soil Cd concentration was 0.6 mg/kg, the Cd accumulation in the fruit of Yellow Pearl was 0.04 mg/kg, making it a low-accumulation S. lycopersicum variety suitable for promoting cultivation in Cd-contaminated soil at 0.6 mg/kg. In conclusion, the Cd accumulation in the fruit of Yellow Pearl is significantly lower than that of Yellow Cherry and even below the Cd limit value for fresh vegetables specified in GB2762-2017. Therefore, Yellow Pearl can be grown as edible crops in soils with Cd concentrations ≤0.6 mg/kg. Furthermore, Yellow Cherry demonstrate strong Cd tolerance and can be used for the remediation of Cd-contaminated soils.

Evaluation of genetic markers for the metabarcoding of Australian marsupials from predator scats

Context DNA recovered from predator faeces (scats) can be used to determine the presence of fauna and shed light on their life histories and inter-species interactions. DNA metabarcoding, which involves concurrent amplification and sequencing of DNA from multiple taxa, represents an important advance by enabling the simultaneous detection of multiple species from such samples. Although an attractive proposition, metabarcoding requires ‘universally’ applicable genetic markers that can discriminate among a broad range of taxa, while also targeting sequences that are sufficiently short to be amplified from degraded DNA. Aims To identify, evaluate, and test metabarcoding DNA markers suitable for the detection of marsupials and other Australian fauna from terrestrial predator scats found in nature. Methods We apply a bioinformatic approach using publicly available DNA databases and a locally derived and marker-specific reference-DNA database to evaluate the diagnostic ability and likelihood of amplification of candidate metabarcoding markers for marsupials and other taxa that may be consumed by predators. Key results We identify two markers (12SV5 and 16SMam) that are suitable for use and successfully identify marsupial sequences at a high level of resolution. These markers work best in combination because they bring complementary levels of primer specificity and diagnostic ability in detecting multiple prey species as well as the predator. We also show that these samples work well in predator scats sampled from the wild in Tasmania. Conclusions These markers provide a useful tool for surveying mammalian predators and their prey and could also be applied to eDNA analyses from other sample types. Improvements to the reference database and further development of markers targeting different taxonomic groups will improve the resolution and usefulness of this approach. Implications Metabarcoding of predator scats provides a potent approach to non-invasive wildlife survey that offers the opportunity for the detection of multiple species across all vertebrates.

Aptamer-Modified Nb2C Multifunctional Nanomedicine for Targeted Photothermal/Chemotherapy Combined Therapy of Tumor.

The poor delivery efficiency of nanotherapeutic drugs and their potential off-target toxicity significantly limit their effectiveness and extensive application. An active targeting system with high efficiency and few side effects is a promising strategy for tumor therapy. Herein, a multifunctional nanomedicine Nb2C-PAA-DOX@Apt-M (NDA-M) was constructed for targeted photothermal/chemotherapy (PTT/CHT) combined tumor therapy. The specific targeting ability of aptamer could effectively enhance the absorption of nanomedicine by the MCF-7 cell. By employing Apt-M, the NDA-M nanosheets demonstrated targeted delivery to MCF-7 cells, resulting in enhanced intracellular drug concentration. Under 1060 nm laser irradiation, a rapid temperature increase of the NDA-M was observed within the tumor region to achieve PTT. Meanwhile, CHT was triggered when DOX release was induced by photothermal/acid stimulation. The experimental results demonstrated that aptamer-mediated targeting achieved enhanced PTT/CHT efficacy both in vitro and in vivo. Notably, NDA-M induced complete ablation of solid tumors without any adverse side effects in mice. This study demonstrated new and promising tactics for the development of nanomaterials for targeted tumor therapy.

Changing the Education Paradigm to adapt to the Labor Market

The article explores an urgent problem in modern professional education — the imbalance between the spheres of practical experience and academic education. Education is still focused on academic knowledge, whereas employers are interested in hiring employees capable of quality work immediately after the graduation. The integration of Armenia into the general European educational space makes the problem of education quality even more urgent. The labor market’s shifts, which require specialists to possess specific professional abilities rather than a wealth of information or experience in order to successfully and quickly adjust to a new work environment, worsen this process. This has changed the educational paradigm from a qualification-based model to a competency-based model imperative, which can only be achieved through the recalibration of educational programs to be more adaptive to changing the needs of the labor market. This process has been ongoing for a long time, but the mechanisms for developing and validating programs are still far from perfect and do not always provide for extensive discussion with employers. This article discusses the conceptual principles of recalibration of bachelor’s and master’s degree programs based on the Dublin descriptors and Tuning methodology.

Deficits of the "Good" Eye in Amblyopia: Processing Geometric Properties.

Although fellow eyes of amblyopia are typically considered normal, recent studies have revealed impairments in certain aspects of vision. However, it remains unclear at which level of object processing these impairments occur. This study aims to investigate the functional level of visual perception impairment in the fellow eye of children and adults with amblyopia using the geometric functional hierarchy discrimination task based on Klein Mathematics methodology. Seventy-six patients with amblyopia (40 children and 36 adults) and 77 age-matched healthy controls (40 children and 37 adults) were recruited for this study. The participants completed four sets of geometric hierarchies (in ascending order of stability: Euclidean, affine, projective, and topology) and one set of color discrimination tasks. They were instructed to rapidly and accurately select a distinct shape from the four quadrants. The participants' performance was evaluated using the inverse efficiency (IE) score (IE = response time (RT)/accuracy). The results of IEs show that the fellow eye of children with amblyopia exhibits normal topological processing, yet displays higher IEs in other geometric properties and color processing, suggesting impairments in these specific discrimination abilities. However, adults with amblyopia did not show deficits on any discrimination types compared with adult controls. The lack of compromised topological processing suggests that amblyopia may not have inflicted any damage to the subcortical visual pathways. Furthermore, these deficits observed in the fellow eye tend to diminish significantly during adulthood, implying that amblyopia may potentially hinder the maturation process of the fellow eye.

Enhancing electrochemical performance of lithium-ion batteries with diverse nanomaterials

Abstract Although lithium-ion batteries (LIBs) can be widely used, there are some challenges such as safety risks, lower energy density compared to fossil fuels, high cost, long charging times and limited range in electric vehicles. Nanomaterials, with their unique properties and surface effects, can effectively address these challenges and improve the electrochemical performance of LIBs. This research introduces six types of nanomaterials used in LIBs, including TiS3 nanoflakes, ZnMn2O4 nanobundles, ZrO2 surface-modified cathode material, nitrogen-doped carbon fibers with tin (Sn) nanoparticles, carbon nanosheets, and nanostructured bismuth-carbon composites. These recent advancements in nanomaterials can improve electrochemical performance of LIBs, such as specific capacity, cycling ability and stability. The study offers some innovative insights and approaches in using nanomaterials and synthesizing them for emerging battery technologies. In addition, this research is wished to provide a fresh perspective and methodology that can advance the performance and design of LIBs, and provide a new design approach for nanomaterials.

Specific Game Abilities and their Significance for Determining the Prospects of Youth National Basketball Team Players

Specific Game Abilities and their Significance for Determining the Prospects of Youth National Basketball Team Players

Consistency of Merdeka Curriculum Towards the Profile of Pancasila Students at the Various Education Levels: A Contextual Study

There are various perspectives on the consistency of the Merdeka Curriculum Towards Pancasila profiles at various eds that still need to impact learner efficacy. This article discusses and examines the consistency of the Merdeka Curriculum towards Pancasila Profiles at Various Education Levels. This article used a theoretical study based on a qualitative and quantitative approach. This approach prioritizes theoretical studies, articles, and other sources that are considered very relevant to the discussion. The discussion method uses five levels: In-depth description, holistic approach, qualitative analysis, use of primary data, and limited data generalization. Meanwhile, the quantitative approach uses a questionnaire distribution with 57 items and involves 45 respondents using purposive random sampling. Based on the study of this article, it was found that curriculum consistency Towards the Profile of Pancasila Students at the education level can be categorized as high, with an average score of 75.5. It could be done by prioritizing various positive perspectives to develop a specific ability to achieve the Golden Indonesia in 2045 goal. This research implies that it can be the solution alternative for making future education decisions.

МАТЕМАТИЧЕСКОЕ МОДЕЛИРОВАНИЕ В ДИФФЕРЕНЦИАЛЬНОЙ ДИАГНОСТИКЕ АНЕМИИ ХРОНИЧЕСКИХ ЗАБОЛЕВАНИЙ И ЖЕЛЕЗОДЕФИЦИТНОЙ АНЕМИИ У ПАЦИЕНТОВ С ВОСПАЛИТЕЛЬНЫМИ ЗАБОЛЕВАНИЯМИ СУСТАВОВ

Aim. To develop based on the indicators of clinical blood tests, some biochemical markers, iron metabolism and cytokines a mathematical model that allows with high sensitivity and specificity to conduct differential diagnosis of anemia of chronic diseases (AHD) and iron deficiency anemia (IDA) in patients with inflammatory joint diseases (rheumatoid arthritis (RA), psoriatic arthritis (PSA), ankylosing spondylitis (AS)). Material and methods. The study included 104 patients with inflammatory joint diseases and anemic syndrome (37 males/67 females, age 48.4±5.42 years old), of which 54 patients with RA, 27 patients with PSA and 23 patients with AS. The control group consisted of 22 patients with inflammatory diseases of the joints without anemia (13 males/9 females, age 47.8±3.55 years old), of which 7 patients with RA, 10 with PSA, 5 with AS. For all patients, in addition to hemogram parameters, the concentrations of interleukin-6, interleukin-10, interleukin-1β, interferon-gamma, tumor necrosis factor alpha, ferritin, C-reactive protein, hepcidin, transferrin, soluble transferrin receptor were determined. For quantitative indicators, the median, standard error of the mean, and interquartile range was calculated. The significance of differences between several unrelated groups was determined using the Kruskal-Wallis test. The calculation of a mathematical model for the differential diagnosis of ACD and IDA was carried out using discriminant analysis. Results. As a result of the study, a canonical linear discriminant function (CLDF) was obtained: CLDF = 1.612171-0.002725× Hepcidin -0.005429× Ferritin The coordinates of the centroids are calculated, for ACD it is -1.44222008, and for IDA it is 1.52705656. A patient whose CLDF value is determined based on ferritin and hepcidin concentrations should be classified into the ACD or IDA group based on the minimum distance to the corresponding centroid. The resulting mathematical model has 100% sensitivity and 80% specificity. Conclusions. The equation based on hepcidin and ferritin (obtained from the results of discriminant analysis) allows, with high sensitivity, specificity and information ability, to carry out differential diagnosis of ACD and IDA in patients with inflammatory joints diseases instantly at the stage of initial contact with the doctor. Using of the equation will make it possible to more effectively diagnose and correct these types of anemia in this pathology, including for the purpose of more effective treatment.