Adjara (South Kolkheti), located in the southwestern part of Georgia, it is characterized by warm and humid climate and subtropical climate, which is due to the proximity of the Black Sea. Adjara is remarkably rich in the diversity of flora not only in Georgia, but throughout the Caucasus. At present there are 1837 plant species in the flora of Adjara, 72 of which contain essential oils, they are distributed in 22 families and in 52 genera. Plants containing essential oil belongs: Lamiaceae - 18 species, Asteraceae-17 types, Apiaceae - 9, Cupressaceae-3, Pinaceae-3, Myrtaceae-3. Vital forms are 7 species of trees, 5 species of bushes, 1 species of tree or bushes, 49 species of perennial grass, 6 species of annual grass. According to the geographical coordinates from the sea level up to 0-500 m are spread 36 species containing essential oils, from the sea level up to 500-1000 m 28 species, from the sea level up to 1000 m 2200 m 33 species. According to the origin of species, 48 species are wild relatives, 7 is cultivated as vegetables, 3 species are introduced, 3 species are invasive. According to the percentage content of essential oils there are: 1 species - 0,025-0,04%, 4 species - 0,1-0.44%, 37 species - 0,2-0,4%, 21 Species - 0,7-1,0%, 7 species - 1,0-3,0%, 3 species - 4,0-6,0%. In the studied species the essential oils structure is complex and diverse. Monotarpens are distributed in 10 species, Sesquitterpaces in 5 species, α-pinene in 7 species, β-pinene in 3 species, α- and β- pinene in 16 species, cineol in 8 species, menthol in 6 species, lemonene in 3 species, in single species are found geraniol, borneol, apiol, thujone, karvakrol and others. In the studied species has been identified 3 prospective invasive species, which are distinguished by great resource, not used Georgia as per officinal medicine, but in their home countries (USA, Japan, China) are valuable medicinal plants, these species produced oils containing quantitative analysis, analysis revealed that, Artemissia vulgaris of upper part of the ground contain 0,9% essential oils, with components korizin, tuion, cineol. Perilla nancinensis of upper part of the ground contain 0,88% essential oils; the main component of the essential oil are perilla-ceton and carophylen, Erygeron canadensis upper part of the ground contain 0,93% essential oils and its mainc components are limonene and terpineol. It also contains alcaloyds, flavonoids and tanner materials